New Research In
Physical Sciences
Social Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
- Agricultural Sciences
- Anthropology
- Applied Biological Sciences
- Biochemistry
- Biophysics and Computational Biology
- Cell Biology
- Developmental Biology
- Ecology
- Environmental Sciences
- Evolution
- Genetics
- Immunology and Inflammation
- Medical Sciences
- Microbiology
- Neuroscience
- Pharmacology
- Physiology
- Plant Biology
- Population Biology
- Psychological and Cognitive Sciences
- Sustainability Science
- Systems Biology
Table of Contents
January 21, 2020; vol. 117 no. 3
This Week in PNAS
Inner Workings
An over-the-shoulder look at scientists at work.
- You have accessInner Workings: A massive star dies without a bang, revealing the sensitive nature of supernovae
- Front Matter
Ken Croswell
QnAs
- You have accessQnAs with Sangeeta N. BhatiaPrashant NairPNAS January 21, 2020 117 (3) 1243-1245; first published January 6, 2020. https://doi.org/10.1073/pnas.1922176117
Profile
- You have accessProfile of Mary Lou GuerinotJennifer ViegasPNAS January 21, 2020 117 (3) 1246-1248; first published January 13, 2020. https://doi.org/10.1073/pnas.1921933117
See companion article:
Letters
- You have accessFurther wet-taro evidence from Polynesia’s southernmost Neolithic production marginsIan G. BarberPNAS January 21, 2020 117 (3) 1257-1258; first published January 14, 2020. https://doi.org/10.1073/pnas.1918374117
- You have accessReply to Barber: Marginal evidence for taro production in northern New Zealand between 1200 and 1500 CEMatthew Prebble, Atholl J. Anderson, Paul Augustinus, Joshua Emmitt, Stewart J. Fallon, Louise L. Furey, Simon J. Holdaway, Alex Jorgensen, Thegn N. Ladefoged, Peter J. Matthews, Jean-Yves Meyer, Rebecca Phillipps, Rod Wallace, and Nicholas PorchPNAS January 21, 2020 117 (3) 1259-1260; first published January 14, 2020. https://doi.org/10.1073/pnas.1919037117
See companion article:
- Open AccessMaking inferences about racial disparities in police violenceDean Knox and Jonathan Mummolo
See companion article:
- You have accessYoung unarmed nonsuicidal male victims of fatal use of force are 13 times more likely to be Black than WhiteUlrich Schimmack and Rickard Carlsson
See companion article:
- You have accessReply to Knox and Mummolo and Schimmack and Carlsson: Controlling for crime and population ratesDavid J. Johnson and Joseph Cesario
See companion article:
Brief Reports
- Open AccessScientists’ incentives and attitudes toward public communicationKathleen M. Rose, Ezra M. Markowitz, and Dominique BrossardPNAS January 21, 2020 117 (3) 1274-1276; first published January 7, 2020. https://doi.org/10.1073/pnas.1916740117
See companion article:
- Open AccessEvidence of tool use in a seabird
- From the Cover
Annette L. Fayet, Erpur Snær Hansen, and Dora BiroPNAS January 21, 2020 117 (3) 1277-1279; first published December 30, 2019. https://doi.org/10.1073/pnas.1918060117See companion article:
- Evidence of tool use in a seabird- Dec 30, 2019
- Tool-using puffins prickle the puzzle of cognitive evolution- Jan 22, 2020
See companion article:
- Reply to Auersperg et al.: Puffin tool use is no fluke- May 19, 2020
- Open AccessHost protein glycosylation in nucleic acid vaccines as a potential hurdle in vaccine design for nonviral pathogensAhmet Ozdilek, Amy V. Paschall, Michelle Dookwah, Michael Tiemeyer, and Fikri Y. AvciPNAS January 21, 2020 117 (3) 1280-1282; first published January 6, 2020. https://doi.org/10.1073/pnas.1916131117
Physical Sciences
Applied Physical Sciences
- Open AccessIntermediate states of molecular self-assembly from liquid-cell electron microscopyHuan Wang, Bo Li, Ye-Jin Kim, Oh-Hoon Kwon, and Steve GranickPNAS January 21, 2020 117 (3) 1283-1292; first published January 7, 2020. https://doi.org/10.1073/pnas.1916065117
- You have accessShort solvent model for ion correlations and hydrophobic associationAng Gao, Richard C. Remsing, and John D. WeeksPNAS January 21, 2020 117 (3) 1293-1302; first published January 7, 2020. https://doi.org/10.1073/pnas.1918981117
Biophysics and Computational Biology
- Open AccessBiophysical principles of choanoflagellate self-organizationBen T. Larson, Teresa Ruiz-Herrero, Stacey Lee, Sanjay Kumar, L. Mahadevan, and Nicole KingPNAS January 21, 2020 117 (3) 1303-1311; first published January 2, 2020. https://doi.org/10.1073/pnas.1909447117
- You have accessBraiding topology and the energy landscape of chromosome organization proteinsDana Krepel, Aram Davtyan, Nicholas P. Schafer, Peter G. Wolynes, and José N. OnuchicPNAS January 21, 2020 117 (3) 1468-1477; first published December 30, 2019. https://doi.org/10.1073/pnas.1917750117
See companion article:
- You have accessStructures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filamentsAndrew R. Huehn, Jeffrey P. Bibeau, Anthony C. Schramm, Wenxiang Cao, Enrique M. De La Cruz, and Charles V. SindelarPNAS January 21, 2020 117 (3) 1478-1484; first published January 3, 2020. https://doi.org/10.1073/pnas.1915987117
See companion article:
- You have accessCotranslational folding allows misfolding-prone proteins to circumvent deep kinetic trapsAmir Bitran, William M. Jacobs, Xiadi Zhai, and Eugene ShakhnovichPNAS January 21, 2020 117 (3) 1485-1495; first published January 7, 2020. https://doi.org/10.1073/pnas.1913207117
- Open AccessA compartment size-dependent selective threshold limits mutation accumulation in hierarchical tissuesDániel Grajzel, Imre Derényi, and Gergely J. SzöllősiPNAS January 21, 2020 117 (3) 1606-1611; first published January 6, 2020. https://doi.org/10.1073/pnas.1913104117
Chemistry
- You have accessThe effector mechanism of siRNA spherical nucleic acidsGokay Yamankurt, Robert J. Stawicki, Diana M. Posadas, Joseph Q. Nguyen, Richard W. Carthew, and Chad A. MirkinPNAS January 21, 2020 117 (3) 1312-1320; first published January 3, 2020. https://doi.org/10.1073/pnas.1915907117
- You have accessAn anticancer gold(III)-activated porphyrin scaffold that covalently modifies protein cysteine thiolsKa-Chung Tong, Chun-Nam Lok, Pui-Ki Wan, Di Hu, Yi Man Eva Fung, Xiao-Yong Chang, Song Huang, Haibo Jiang, and Chi-Ming ChePNAS January 21, 2020 117 (3) 1321-1329; first published January 2, 2020. https://doi.org/10.1073/pnas.1915202117
- You have accessHighly efficient binary copper−iron catalyst for photoelectrochemical carbon dioxide reduction toward methaneBaowen Zhou, Pengfei Ou, Nick Pant, Shaobo Cheng, Srinivas Vanka, Sheng Chu, Roksana Tonny Rashid, Gianluigi Botton, Jun Song, and Zetian MiPNAS January 21, 2020 117 (3) 1330-1338; first published January 3, 2020. https://doi.org/10.1073/pnas.1911159117
- You have accessA unified machine-learning protocol for asymmetric catalysis as a proof of concept demonstration using asymmetric hydrogenationSukriti Singh, Monika Pareek, Avtar Changotra, Sayan Banerjee, Bangaru Bhaskararao, P. Balamurugan, and Raghavan B. SunojPNAS January 21, 2020 117 (3) 1339-1345; first published January 8, 2020. https://doi.org/10.1073/pnas.1916392117
- You have accessDesigning cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity in Streptococcus pneumoniaeYifang Yang, Jingjun Lin, Anthony Harrington, Gabriel Cornilescu, Gee W. Lau, and Yftah Tal-GanPNAS January 21, 2020 117 (3) 1689-1699; first published January 8, 2020. https://doi.org/10.1073/pnas.1915812117
Earth, Atmospheric, and Planetary Sciences
- You have accessThe role of saltwater and waves in continental shelf formation with seaward migrating clinoform
- Inaugural Article
Toshiki Iwasaki and Gary ParkerPNAS January 21, 2020 117 (3) 1266-1273; first published January 7, 2020. https://doi.org/10.1073/pnas.1909572117See companion article:
- QnAs with Gary Parker- Aug 17, 2020
- Open AccessAustralasian impact crater buried under the Bolaven volcanic field, Southern Laos
- From the Cover
Kerry Sieh, Jason Herrin, Brian Jicha, Dayana Schonwalder Angel, James D. P. Moore, Paramesh Banerjee, Weerachat Wiwegwin, Vanpheng Sihavong, Brad Singer, Tawachai Chualaowanich, and Punya CharusiriPNAS January 21, 2020 117 (3) 1346-1353; first published December 30, 2019. https://doi.org/10.1073/pnas.1904368116See companion article:
- You have accessFast oxidation of sulfur dioxide by hydrogen peroxide in deliquesced aerosol particlesTengyu Liu, Simon L. Clegg, and Jonathan P. D. AbbattPNAS January 21, 2020 117 (3) 1354-1359; first published January 3, 2020. https://doi.org/10.1073/pnas.1916401117
- You have accessOxidized micrometeorites suggest either high pCO2 or low pN2 during the NeoarcheanRebecca C. Payne, Don Brownlee, and James F. KastingPNAS January 21, 2020 117 (3) 1360-1366; first published January 6, 2020. https://doi.org/10.1073/pnas.1910698117
- You have accessGeographically divergent evolutionary and ecological legacies shape mammal biodiversity in the global tropics and subtropicsJohn Rowan, Lydia Beaudrot, Janet Franklin, Kaye E. Reed, Irene E. Smail, Andrew Zamora, and Jason M. KamilarPNAS January 21, 2020 117 (3) 1559-1565; first published December 16, 2019. https://doi.org/10.1073/pnas.1910489116
See companion article:
Engineering
- You have accessBioinspired sonar reflectors as guiding beacons for autonomous navigationRalph Simon, Stefan Rupitsch, Markus Baumann, Huan Wu, Herbert Peremans, and Jan SteckelPNAS January 21, 2020 117 (3) 1367-1374; first published January 6, 2020. https://doi.org/10.1073/pnas.1909890117
- You have accessInfrared optical and thermal properties of microstructures in butterfly wingsAnirudh Krishna, Xiao Nie, Andrew D. Warren, Jorge E. Llorente-Bousquets, Adriana D. Briscoe, and Jaeho LeePNAS January 21, 2020 117 (3) 1566-1572; first published January 9, 2020. https://doi.org/10.1073/pnas.1906356117
Environmental Sciences
- You have accessChannelization cascade in landscape evolutionSara Bonetti, Milad Hooshyar, Carlo Camporeale, and Amilcare PorporatoPNAS January 21, 2020 117 (3) 1375-1382; first published January 8, 2020. https://doi.org/10.1073/pnas.1911817117
- You have accessHigh productivity in hybrid-poplar plantations without isoprene emission to the atmosphereRussell K. Monson, Barbro Winkler, Todd N. Rosenstiel, Katja Block, Juliane Merl-Pham, Steven H. Strauss, Kori Ault, Jason Maxfield, David J. P. Moore, Nicole A. Trahan, Amberly A. Neice, Ian Shiach, Greg A. Barron-Gafford, Peter Ibsen, Joel T. McCorkel, Jörg Bernhardt, and Joerg-Peter SchnitzlerPNAS January 21, 2020 117 (3) 1596-1605; first published January 6, 2020. https://doi.org/10.1073/pnas.1912327117
Physics
- You have accessOptimizing Brownian escape rates by potential shapingMarie Chupeau, Jannes Gladrow, Alexei Chepelianskii, Ulrich F. Keyser, and Emmanuel TrizacPNAS January 21, 2020 117 (3) 1383-1388; first published December 16, 2019. https://doi.org/10.1073/pnas.1910677116
See companion article:
- Optimizing Brownian escape rates by potential shaping- Dec 16, 2019
- Enhancing transport by shaping barriers- Jan 14, 2020
Social Sciences
Social Sciences
- Open AccessA randomized trial of a lab-embedded discourse intervention to improve research ethicsDena K. Plemmons, Erica N. Baranski, Kyle Harp, David D. Lo, Courtney K. Soderberg, Timothy M. Errington, Brian A. Nosek, and Kevin M. EsterlingPNAS January 21, 2020 117 (3) 1389-1394; first published January 9, 2020. https://doi.org/10.1073/pnas.1917848117
Biological Sciences
Applied Biological Sciences
- You have accessBioinspired sonar reflectors as guiding beacons for autonomous navigationRalph Simon, Stefan Rupitsch, Markus Baumann, Huan Wu, Herbert Peremans, and Jan SteckelPNAS January 21, 2020 117 (3) 1367-1374; first published January 6, 2020. https://doi.org/10.1073/pnas.1909890117
- You have accessRetroconversion of estrogens into androgens by bacteria via a cobalamin-mediated methylation
- From the Cover
Po-Hsiang Wang, Yi-Lung Chen, Sean Ting-Shyang Wei, Kan Wu, Tzong-Huei Lee, Tien-Yu Wu, and Yin-Ru ChiangPNAS January 21, 2020 117 (3) 1395-1403; first published December 17, 2019. https://doi.org/10.1073/pnas.1914380117See companion article:
- Open AccessBioderivatization as a concept for renewable production of chemicals that are toxic or poorly soluble in the liquid phasePachara Sattayawat, Ian Sofian Yunus, and Patrik R. JonesPNAS January 21, 2020 117 (3) 1404-1413; first published January 8, 2020. https://doi.org/10.1073/pnas.1914069117
Biochemistry
- You have accessThe effector mechanism of siRNA spherical nucleic acidsGokay Yamankurt, Robert J. Stawicki, Diana M. Posadas, Joseph Q. Nguyen, Richard W. Carthew, and Chad A. MirkinPNAS January 21, 2020 117 (3) 1312-1320; first published January 3, 2020. https://doi.org/10.1073/pnas.1915907117
- You have accessActivation by substoichiometric inhibitionMelisa Merdanovic, Steven G. Burston, Anna Laura Schmitz, Steffen Köcher, Stefan Knapp, Tim Clausen, Markus Kaiser, Robert Huber, and Michael EhrmannPNAS January 21, 2020 117 (3) 1414-1418; first published January 6, 2020. https://doi.org/10.1073/pnas.1918721117
- Open AccessA de novo peroxidase is also a promiscuous yet stereoselective carbene transferaseRichard Stenner, Jack W. Steventon, Annela Seddon, and J. L. Ross AndersonPNAS January 21, 2020 117 (3) 1419-1428; first published January 2, 2020. https://doi.org/10.1073/pnas.1915054117
- Open AccessLong-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiationBridget Y. Huang and Israel S. FernándezPNAS January 21, 2020 117 (3) 1429-1437; first published January 3, 2020. https://doi.org/10.1073/pnas.1916436117
- Open AccessCryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycansTzu-Jing Yang, Yen-Chen Chang, Tzu-Ping Ko, Piotr Draczkowski, Yu-Chun Chien, Yuan-Chih Chang, Kuen-Phon Wu, Kay-Hooi Khoo, Hui-Wen Chang, and Shang-Te Danny HsuPNAS January 21, 2020 117 (3) 1438-1446; first published January 3, 2020. https://doi.org/10.1073/pnas.1908898117
- Open AccessRotary catalysis of bovine mitochondrial F1-ATPase studied by single-molecule experimentsRyohei Kobayashi, Hiroshi Ueno, Chun-Biu Li, and Hiroyuki NojiPNAS January 21, 2020 117 (3) 1447-1456; first published January 2, 2020. https://doi.org/10.1073/pnas.1909407117
- Open AccessTranslation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNAPeiyuan Zhang, Hye-Jin Park, Jie Zhang, Eunsung Junn, Ryan J. Andrews, Sai Pradeep Velagapudi, Daniel Abegg, Kamalakannan Vishnu, Matthew G. Costales, Jessica L. Childs-Disney, Alexander Adibekian, Walter N. Moss, M. Maral Mouradian, and Matthew D. DisneyPNAS January 21, 2020 117 (3) 1457-1467; first published January 3, 2020. https://doi.org/10.1073/pnas.1905057117
Biophysics and Computational Biology
- Open AccessIntermediate states of molecular self-assembly from liquid-cell electron microscopyHuan Wang, Bo Li, Ye-Jin Kim, Oh-Hoon Kwon, and Steve GranickPNAS January 21, 2020 117 (3) 1283-1292; first published January 7, 2020. https://doi.org/10.1073/pnas.1916065117
- You have accessBraiding topology and the energy landscape of chromosome organization proteinsDana Krepel, Aram Davtyan, Nicholas P. Schafer, Peter G. Wolynes, and José N. OnuchicPNAS January 21, 2020 117 (3) 1468-1477; first published December 30, 2019. https://doi.org/10.1073/pnas.1917750117
See companion article:
- You have accessStructures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filamentsAndrew R. Huehn, Jeffrey P. Bibeau, Anthony C. Schramm, Wenxiang Cao, Enrique M. De La Cruz, and Charles V. SindelarPNAS January 21, 2020 117 (3) 1478-1484; first published January 3, 2020. https://doi.org/10.1073/pnas.1915987117
See companion article:
- You have accessCotranslational folding allows misfolding-prone proteins to circumvent deep kinetic trapsAmir Bitran, William M. Jacobs, Xiadi Zhai, and Eugene ShakhnovichPNAS January 21, 2020 117 (3) 1485-1495; first published January 7, 2020. https://doi.org/10.1073/pnas.1913207117
- You have accessImproved protein structure prediction using predicted interresidue orientationsJianyi Yang, Ivan Anishchenko, Hahnbeom Park, Zhenling Peng, Sergey Ovchinnikov, and David BakerPNAS January 21, 2020 117 (3) 1496-1503; first published January 2, 2020. https://doi.org/10.1073/pnas.1914677117
- You have accessMolecular mechanism of the chitinolytic peroxygenase reactionBastien Bissaro, Bennett Streit, Ingvild Isaksen, Vincent G. H. Eijsink, Gregg T. Beckham, Jennifer L. DuBois, and Åsmund K. RøhrPNAS January 21, 2020 117 (3) 1504-1513; first published January 6, 2020. https://doi.org/10.1073/pnas.1904889117
Cell Biology
- You have accessA cell atlas of the adult Drosophila midgutRuei-Jiun Hung, Yanhui Hu, Rory Kirchner, Yifang Liu, Chiwei Xu, Aram Comjean, Sudhir Gopal Tattikota, Fangge Li, Wei Song, Shannan Ho Sui, and Norbert PerrimonPNAS January 21, 2020 117 (3) 1514-1523; first published January 8, 2020. https://doi.org/10.1073/pnas.1916820117
- You have accessLoss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAsDritan Liko, Andrzej Rzepiela, Vanja Vukojevic, Mihaela Zavolan, and Michael N. HallPNAS January 21, 2020 117 (3) 1524-1532; first published January 9, 2020. https://doi.org/10.1073/pnas.1918931117
- Open AccessQuantitative microscopy reveals dynamics and fate of clustered IRE1αVladislav Belyy, Ngoc-Han Tran, and Peter WalterPNAS January 21, 2020 117 (3) 1533-1542; first published December 23, 2019. https://doi.org/10.1073/pnas.1915311117
See companion article:
- Dynamics and clustering of IRE1α during ER stress- Feb 04, 2020
- Open AccessThe clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumoniaGareth B. Kitchen, Peter S. Cunningham, Toryn M. Poolman, Mudassar Iqbal, Robert Maidstone, Matthew Baxter, James Bagnall, Nicola Begley, Ben Saer, Tracy Hussell, Laura C. Matthews, David H. Dockrell, Hannah J. Durrington, Julie E. Gibbs, John F. Blaikley, Andrew S. Loudon, and David W. RayPNAS January 21, 2020 117 (3) 1543-1551; first published January 3, 2020. https://doi.org/10.1073/pnas.1915932117
Developmental Biology
- You have accessGlobal shape of Toll activation is determined by wntD enhancer propertiesNeta Rahimi, Shari Carmon, Inna Averbukh, Farzaneh Khajouei, Saurabh Sinha, Eyal D. Schejter, Naama Barkai, and Ben-Zion ShiloPNAS January 21, 2020 117 (3) 1552-1558; first published January 3, 2020. https://doi.org/10.1073/pnas.1918268117
Ecology
- You have accessGeographically divergent evolutionary and ecological legacies shape mammal biodiversity in the global tropics and subtropicsJohn Rowan, Lydia Beaudrot, Janet Franklin, Kaye E. Reed, Irene E. Smail, Andrew Zamora, and Jason M. KamilarPNAS January 21, 2020 117 (3) 1559-1565; first published December 16, 2019. https://doi.org/10.1073/pnas.1910489116
See companion article:
- You have accessInfrared optical and thermal properties of microstructures in butterfly wingsAnirudh Krishna, Xiao Nie, Andrew D. Warren, Jorge E. Llorente-Bousquets, Adriana D. Briscoe, and Jaeho LeePNAS January 21, 2020 117 (3) 1566-1572; first published January 9, 2020. https://doi.org/10.1073/pnas.1906356117
- You have accessLand-use history impacts functional diversity across multiple trophic groupsGaëtane Le Provost, Isabelle Badenhausser, Yoann Le Bagousse-Pinguet, Yann Clough, Laura Henckel, Cyrille Violle, Vincent Bretagnolle, Marilyn Roncoroni, Peter Manning, and Nicolas GrossPNAS January 21, 2020 117 (3) 1573-1579; first published January 6, 2020. https://doi.org/10.1073/pnas.1910023117
- Open AccessScaling the risk landscape drives optimal life-history strategies and the evolution of grazing
- From the Cover
Uttam Bhat, Christopher P. Kempes, and Justin D. YeakelPNAS January 21, 2020 117 (3) 1580-1586; first published December 17, 2019. https://doi.org/10.1073/pnas.1907998117See companion article:
- Open AccessRecovery of critically endangered Nassau grouper (Epinephelus striatus) in the Cayman Islands following targeted conservation actions
- From the Cover
Lynn Waterhouse, Scott A. Heppell, Christy V. Pattengill-Semmens, Croy McCoy, Phillippe Bush, Bradley C. Johnson, and Brice X. SemmensPNAS January 21, 2020 117 (3) 1587-1595; first published January 6, 2020. https://doi.org/10.1073/pnas.1917132117See companion article:
Environmental Sciences
- You have accessHigh productivity in hybrid-poplar plantations without isoprene emission to the atmosphereRussell K. Monson, Barbro Winkler, Todd N. Rosenstiel, Katja Block, Juliane Merl-Pham, Steven H. Strauss, Kori Ault, Jason Maxfield, David J. P. Moore, Nicole A. Trahan, Amberly A. Neice, Ian Shiach, Greg A. Barron-Gafford, Peter Ibsen, Joel T. McCorkel, Jörg Bernhardt, and Joerg-Peter SchnitzlerPNAS January 21, 2020 117 (3) 1596-1605; first published January 6, 2020. https://doi.org/10.1073/pnas.1912327117
Evolution
- Open AccessBiophysical principles of choanoflagellate self-organizationBen T. Larson, Teresa Ruiz-Herrero, Stacey Lee, Sanjay Kumar, L. Mahadevan, and Nicole KingPNAS January 21, 2020 117 (3) 1303-1311; first published January 2, 2020. https://doi.org/10.1073/pnas.1909447117
- Open AccessA compartment size-dependent selective threshold limits mutation accumulation in hierarchical tissuesDániel Grajzel, Imre Derényi, and Gergely J. SzöllősiPNAS January 21, 2020 117 (3) 1606-1611; first published January 6, 2020. https://doi.org/10.1073/pnas.1913104117
- Open AccessFin ray patterns at the fin-to-limb transitionThomas A. Stewart, Justin B. Lemberg, Natalia K. Taft, Ihna Yoo, Edward B. Daeschler, and Neil H. ShubinPNAS January 21, 2020 117 (3) 1612-1620; first published December 30, 2019. https://doi.org/10.1073/pnas.1915983117
Genetics
- Open AccessCystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditionsAaron C. Miller, Alejandro P. Comellas, Douglas B. Hornick, David A. Stoltz, Joseph E. Cavanaugh, Alicia K. Gerke, Michael J. Welsh, Joseph Zabner, and Philip M. PolgreenPNAS January 21, 2020 117 (3) 1621-1627; first published December 27, 2019. https://doi.org/10.1073/pnas.1914912117
See companion article:
- Open AccessLarge-scale contractions of Friedreich’s ataxia GAA repeats in yeast occur during DNA replication due to their triplex-forming abilityAlexandra N. Khristich, Jillian F. Armenia, Robert M. Matera, Anna A. Kolchinski, and Sergei M. MirkinPNAS January 21, 2020 117 (3) 1628-1637; first published January 7, 2020. https://doi.org/10.1073/pnas.1913416117
- Open AccessPresynaptic MAST kinase controls opposing postsynaptic responses to convey stimulus valence in Caenorhabditis elegansShunji Nakano, Muneki Ikeda, Yuki Tsukada, Xianfeng Fei, Takamasa Suzuki, Yusuke Niino, Rhea Ahluwalia, Ayana Sano, Rumi Kondo, Kunio Ihara, Atsushi Miyawaki, Koichi Hashimoto, Tetsuya Higashiyama, and Ikue MoriPNAS January 21, 2020 117 (3) 1638-1647; first published January 7, 2020. https://doi.org/10.1073/pnas.1909240117
Immunology and Inflammation
- You have accessStructural insight into T cell coinhibition by PD-1H (VISTA)Benjamin T. Slater, Xue Han, Lieping Chen, and Yong XiongPNAS January 21, 2020 117 (3) 1648-1657; first published January 9, 2020. https://doi.org/10.1073/pnas.1908711117
Medical Sciences
- Open AccessIdentification and characterization of extrachromosomal circular DNA in maternal plasmaSarah T. K. Sin, Peiyong Jiang, Jiaen Deng, Lu Ji, Suk Hang Cheng, Anindya Dutta, Tak Y. Leung, K. C. Allen Chan, Rossa W. K. Chiu, and Y. M. Dennis LoPNAS January 21, 2020 117 (3) 1658-1665; first published January 3, 2020. https://doi.org/10.1073/pnas.1914949117
- Open AccessHigh-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse modelRebecca A. Luchtel, Tushar Bhagat, Kith Pradhan, William R. Jacobs Jr, Mark Levine, Amit Verma, and Niraj ShenoyPNAS January 21, 2020 117 (3) 1666-1677; first published January 7, 2020. https://doi.org/10.1073/pnas.1908158117
- Open AccessExpansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytesEleftherios Michailidis, Koen Vercauteren, Liliana Mancio-Silva, Linda Andrus, Cyprien Jahan, Inna Ricardo-Lax, Chenhui Zou, Mohammad Kabbani, Paul Park, Corrine Quirk, Christina Pyrgaki, Brandon Razooky, Lieven Verhoye, Irene Zoluthkin, Wei-Yu Lu, Stuart J. Forbes, Luis Chiriboga, Neil D. Theise, Roland W. Herzog, Hiroshi Suemizu, William M. Schneider, Amir Shlomai, Philip Meuleman, Sangeeta N. Bhatia, Charles M. Rice, and Ype P. de JongPNAS January 21, 2020 117 (3) 1678-1688; first published January 8, 2020. https://doi.org/10.1073/pnas.1919035117
Microbiology
- You have accessDesigning cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity in Streptococcus pneumoniaeYifang Yang, Jingjun Lin, Anthony Harrington, Gabriel Cornilescu, Gee W. Lau, and Yftah Tal-GanPNAS January 21, 2020 117 (3) 1689-1699; first published January 8, 2020. https://doi.org/10.1073/pnas.1915812117
- You have accessBile acids and ceramide overcome the entry restriction for GII.3 human norovirus replication in human intestinal enteroidsKosuke Murakami, Victoria R. Tenge, Umesh C. Karandikar, Shih-Ching Lin, Sasirekha Ramani, Khalil Ettayebi, Sue E. Crawford, Xi-Lei Zeng, Frederick H. Neill, B. Vijayalakshmi Ayyar, Kazuhiko Katayama, David Y. Graham, Erhard Bieberich, Robert L. Atmar, and Mary K. EstesPNAS January 21, 2020 117 (3) 1700-1710; first published January 2, 2020. https://doi.org/10.1073/pnas.1910138117
- You have accessMitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistanceYeqi Li, Yuanwei Zhang, Chi Zhang, Hongchen Wang, Xiaolei Wei, Peiying Chen, and Ling LuPNAS January 21, 2020 117 (3) 1711-1721; first published December 6, 2019. https://doi.org/10.1073/pnas.1911560116
See companion article:
- You have accessA promiscuous inflammasome sparks replication of a common tumor virusEric M. Burton, Raphaela Goldbach-Mansky, and Sumita Bhaduri-McIntoshPNAS January 21, 2020 117 (3) 1722-1730; first published January 9, 2020. https://doi.org/10.1073/pnas.1919133117
- Open AccessRobust hepatitis E virus infection and transcriptional response in human hepatocytesDaniel Todt, Martina Friesland, Nora Moeller, Dimas Praditya, Volker Kinast, Yannick Brüggemann, Leonard Knegendorf, Thomas Burkard, Joerg Steinmann, Rani Burm, Lieven Verhoye, Avista Wahid, Toni Luise Meister, Michael Engelmann, Vanessa M. Pfankuche, Christina Puff, Florian W. R. Vondran, Wolfgang Baumgärtner, Philip Meuleman, Patrick Behrendt, and Eike SteinmannPNAS January 21, 2020 117 (3) 1731-1741; first published January 2, 2020. https://doi.org/10.1073/pnas.1912307117
Neuroscience
- You have accessMicroglial IRF5-IRF4 regulatory axis regulates neuroinflammation after cerebral ischemia and impacts stroke outcomesAbdullah Al Mamun, Anjali Chauhan, Shaohua Qi, Conelius Ngwa, Yan Xu, Romana Sharmeen, Amy L. Hazen, Jun Li, Jaroslaw A. Aronowski, Louise D. McCullough, and Fudong LiuPNAS January 21, 2020 117 (3) 1742-1752; first published December 31, 2019. https://doi.org/10.1073/pnas.1914742117
- You have accessImpaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in miceJan Wenzel, Cathrin E. Hansen, Carla Bettoni, Miriam A. Vogt, Beate Lembrich, Rentsenkhand Natsagdorj, Gianna Huber, Josefine Brands, Kjestine Schmidt, Julian C. Assmann, Ines Stölting, Kathrin Saar, Jan Sedlacik, Jens Fiehler, Peter Ludewig, Michael Wegmann, Nina Feller, Marius Richter, Helge Müller-Fielitz, Thomas Walther, Gabriele M. König, Evi Kostenis, Walter Raasch, Norbert Hübner, Peter Gass, Stefan Offermanns, Cor de Wit, Carsten A. Wagner, and Markus SchwaningerPNAS January 21, 2020 117 (3) 1753-1761; first published January 2, 2020. https://doi.org/10.1073/pnas.1907467117
- You have accessNK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathyRachael H. Earls, Kelly B. Menees, Jaegwon Chung, Claire-Anne Gutekunst, Hyun Joon Lee, Manuel G. Hazim, Balázs Rada, Levi B. Wood, and Jae-Kyung LeePNAS January 21, 2020 117 (3) 1762-1771; first published January 3, 2020. https://doi.org/10.1073/pnas.1909110117
Physiology
- You have accessInternal fluid pressure influences muscle contractile forceDavid A. Sleboda and Thomas J. RobertsPNAS January 21, 2020 117 (3) 1772-1778; first published December 26, 2019. https://doi.org/10.1073/pnas.1914433117
See companion article:
- Internal fluid pressure influences muscle contractile force- Dec 26, 2019
- Muscle force is modulated by internal pressure- Jan 08, 2020
- Open AccessSpecialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubulePablo Cabrero, Selim Terhzaz, Anthony J. Dornan, Saurav Ghimire, Heather L. Holmes, Daniel R. Turin, Michael F. Romero, Shireen A. Davies, and Julian A. T. DowPNAS January 21, 2020 117 (3) 1779-1787; first published January 6, 2020. https://doi.org/10.1073/pnas.1915943117
- You have accessCryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayerPramod Kumar, Yuhang Wang, Zhening Zhang, Zhiyu Zhao, Gisela D. Cymes, Emad Tajkhorshid, and Claudio GrosmanPNAS January 21, 2020 117 (3) 1788-1798; first published January 7, 2020. https://doi.org/10.1073/pnas.1906823117
Plant Biology
- You have accessThe maize heterotrimeric G protein β subunit controls shoot meristem development and immune responsesQingyu Wu, Fang Xu, Lei Liu, Si Nian Char, Yezhang Ding, Byoung Il Je, Eric Schmelz, Bing Yang, and David JacksonPNAS January 21, 2020 117 (3) 1799-1805; first published December 18, 2019. https://doi.org/10.1073/pnas.1917577116
See companion article:
- You have accessThe rhizobial autotransporter determines the symbiotic nitrogen fixation activity of Lotus japonicus in a host-specific mannerYoshikazu Shimoda, Yuki Nishigaya, Hiroko Yamaya-Ito, Noritoshi Inagaki, Yosuke Umehara, Hideki Hirakawa, Shusei Sato, Toshimasa Yamazaki, and Makoto HayashiPNAS January 21, 2020 117 (3) 1806-1815; first published January 3, 2020. https://doi.org/10.1073/pnas.1913349117
Corrections
- You have accessCorrection for Perkins, Core Concept: Albedo is a simple concept that plays complicated roles in climate and astronomyPNAS January 21, 2020 117 (3) 1816; first published January 13, 2020. https://doi.org/10.1073/pnas.1922493117
- You have accessCorrection for Mann, Core Concept: To improve weather and climate models, researchers are chasing atmospheric gravity wavesPNAS January 21, 2020 117 (3) 1817; first published January 13, 2020. https://doi.org/10.1073/pnas.1922468117
- You have accessCorrection for Porter et al., Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinomaPNAS January 21, 2020 117 (3) 1818; first published January 13, 2020. https://doi.org/10.1073/pnas.1922469117
- You have accessCorrection for Hu et al., Structural bases for F plasmid conjugation and F pilus biogenesis in Escherichia coliPNAS January 21, 2020 117 (3) 1819; first published January 13, 2020. https://doi.org/10.1073/pnas.1922471117
Commentaries
See companion article:
See companion article:
See companion article: