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Research Article

Brain-wide functional architecture remodeling by alcohol dependence and abstinence

View ORCID ProfileAdam Kimbrough, Daniel J. Lurie, Andres Collazo, Max Kreifeldt, Harpreet Sidhu, Giovana Camila Macedo, Mark D’Esposito, Candice Contet, and Olivier George
PNAS January 28, 2020 117 (4) 2149-2159; first published January 14, 2020; https://doi.org/10.1073/pnas.1909915117
Adam Kimbrough
aDepartment of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA 92093;
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  • ORCID record for Adam Kimbrough
Daniel J. Lurie
bHelen Wills Neuroscience Institute, University of California, Berkeley, CA 94720;
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Andres Collazo
cBeckman Institute, California Institute of Technology, Pasadena, CA 91125;
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Max Kreifeldt
dDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037
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Harpreet Sidhu
dDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037
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Giovana Camila Macedo
dDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037
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Mark D’Esposito
bHelen Wills Neuroscience Institute, University of California, Berkeley, CA 94720;
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Candice Contet
dDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037
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Olivier George
aDepartment of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA 92093;
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  • For correspondence: olgeorge@ucsd.edu
  1. Edited by Huda Akil, University of Michigan, Ann Arbor, MI, and approved December 16, 2019 (received for review June 10, 2019)

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Article Information

vol. 117 no. 4 2149-2159
DOI: 
https://doi.org/10.1073/pnas.1909915117
PubMed: 
31937658

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue January 28, 2020.
  • Published first January 14, 2020.

Article Versions

  • Previous version (January 14, 2020 - 08:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2020 Published under the PNAS license.

Author Information

  1. Adam Kimbrougha,
  2. Daniel J. Lurieb,
  3. Andres Collazoc,
  4. Max Kreifeldtd,
  5. Harpreet Sidhud,
  6. Giovana Camila Macedod,
  7. Mark D’Espositob,
  8. Candice Contetd, and
  9. Olivier Georgea,1
  1. aDepartment of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA 92093;
  2. bHelen Wills Neuroscience Institute, University of California, Berkeley, CA 94720;
  3. cBeckman Institute, California Institute of Technology, Pasadena, CA 91125;
  4. dDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037
  1. Edited by Huda Akil, University of Michigan, Ann Arbor, MI, and approved December 16, 2019 (received for review June 10, 2019)

Footnotes

  • ↵1To whom correspondence may be addressed. Email: olgeorge{at}ucsd.edu.
  • Author contributions: A.K. and O.G. designed research; A.K., A.C., M.K., H.S., G.C.M., and C.C. performed research; D.J.L. and M.D. contributed new reagents/analytic tools; A.K., D.J.L., M.D., and C.C. analyzed data; and A.K. and O.G. wrote the paper.

  • The authors declare no competing interest.

  • This article is a PNAS Direct Submission.

  • This article contains supporting information online at https://www.pnas.org/lookup/suppl/doi:10.1073/pnas.1909915117/-/DCSupplemental.

Cited By...

  • 5 Citations
  • 5 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats
    Adam Kimbrough, Jenni Kononoff, Sierra Simpson, Marsida Kallupi, Sharona Sedighim, Kenia Palomino, Dana Conlisk, Jeremiah D. Momper, Giordano de Guglielmo, Olivier George
    Psychopharmacology 2020 237 5
  • Chronic voluntary caffeine intake in male Wistar rats reveals individual differences in addiction-like behavior
    Christine H. Lee, Olivier George, Adam Kimbrough
    Pharmacology Biochemistry and Behavior 2020 191
  • Absence of effects of intermittent access to alcohol on negative affective and anxiety-like behaviors in male and female C57BL/6J mice
    Solal Bloch, Jennifer A. Rinker, Madison M. Marcus, Patrick J. Mulholland
    Alcohol 2020 88
  • Leveraging Neural Networks in Preclinical Alcohol Research
    Lauren C. Smith, Adam Kimbrough
    Brain Sciences 2020 10 9
  • Vulnerability to addiction
    R. Maldonado, P. Calvé, A. García-Blanco, L. Domingo-Rodriguez, E. Senabre, E. Martín-García
    Neuropharmacology 2021

Article usage

Article usage: January 2020 to January 2021

AbstractFullPdf
Jan 20203024474278
Feb 2020163416698
Mar 20205167249
Apr 20203345676
May 20202334128
Jun 20201963216
Jul 20201048536
Aug 20202817450
Sep 20203518057
Oct 20203015857
Nov 20202819266
Dec 20204119570
Total 202062031825881
Jan 20212012648
Total 20212012648
Total62231951929
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Brain-wide functional architecture remodeling by alcohol dependence and abstinence
Adam Kimbrough, Daniel J. Lurie, Andres Collazo, Max Kreifeldt, Harpreet Sidhu, Giovana Camila Macedo, Mark D’Esposito, Candice Contet, Olivier George
Proceedings of the National Academy of Sciences Jan 2020, 117 (4) 2149-2159; DOI: 10.1073/pnas.1909915117

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Brain-wide functional architecture remodeling by alcohol dependence and abstinence
Adam Kimbrough, Daniel J. Lurie, Andres Collazo, Max Kreifeldt, Harpreet Sidhu, Giovana Camila Macedo, Mark D’Esposito, Candice Contet, Olivier George
Proceedings of the National Academy of Sciences Jan 2020, 117 (4) 2149-2159; DOI: 10.1073/pnas.1909915117
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