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Table of Contents
November 24, 2020; vol. 117 no. 47
Opinion
Leading scientists discuss current issues
- You have accessOpinion: To stop the next pandemic, we need to unravel the origins of COVID-19
- Front Matter
David A. RelmanPNAS November 24, 2020 117 (47) 29246-29248; first published November 3, 2020. https://doi.org/10.1073/pnas.2021133117
Inner Workings
An over-the-shoulder look at scientists at work
- You have accessInner Workings: Physicists look to a new telescope to understand neutron stars and matter at the extremes
- Front Matter
Stephen OrnesPNAS November 24, 2020 117 (47) 29249-29252; first published November 4, 2020. https://doi.org/10.1073/pnas.2021447117
QnAs
Interviews with leading scientific researchers and newsmakers
- You have accessQnAs with Enquye Negash, Zeresenay Alemseged, and Jonathan WynnTinsley H. DavisPNAS November 24, 2020 117 (47) 29253-29256; first published November 16, 2020. https://doi.org/10.1073/pnas.2021561117
See companion article:
Retrospective
- You have accessDavid Blackwell, 1919–2010: An explorer in mathematics and statisticsPeter J. BickelPNAS November 24, 2020 117 (47) 29257-29259; first published November 13, 2020. https://doi.org/10.1073/pnas.2020164117
Perspective
- You have accessTargeting the renin−angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, and challengesKrishna Sriram, Rohit Loomba, and Paul A. InselPNAS November 24, 2020 117 (47) 29274-29282; first published November 17, 2020. https://doi.org/10.1073/pnas.2009875117
Letters
- You have accessrs1769793 variant reduces EGLN1 expression in skeletal muscle and hippocampus and contributes to high aerobic capacity in hypoxiaGuiyou Liu, Wenbo Zhao, Haihua Zhang, Tao Wang, Zhifa Han, and Xunming JiPNAS November 24, 2020 117 (47) 29283-29285; first published October 27, 2020. https://doi.org/10.1073/pnas.2010073117
- You have accessReply to Liu et al.: The Andean EGLN1 adaptive allele could be a loss of function variant that increases HIF1-α in skeletal muscleTom D. Brutsaert, Melissa Kiyamu, Gianpietro Elias Revollendo, Jenna L. Isherwood, Frank S. Lee, Maria Rivera-Ch, Fabiola Leon-Velarde, Sudipta Ghosh, and Abigail W. BighamPNAS November 24, 2020 117 (47) 29286-29287; first published October 27, 2020. https://doi.org/10.1073/pnas.2012199117
See companion article:
- You have accessWhat is the correct stoichiometry of Kv2.1:Kv6.4 heteromers?Aditya Pisupati, Keith J. Mickolajczyk, William O. Hancock, and Timothy JeglaPNAS November 24, 2020 117 (47) 29288-29289; first published October 20, 2020. https://doi.org/10.1073/pnas.2017827117
- You have accessReply to Pisupati et al.: Evaluating single subunit counting data to find the correct stoichiometryLena Möller, Glenn Regnier, Alain J. Labro, Dirk J. Snyders, and Rikard BlunckPNAS November 24, 2020 117 (47) 29290-29291; first published October 20, 2020. https://doi.org/10.1073/pnas.2018077117
See companion article:
Colloquium on Brain Produces Mind by Modeling
Introduction
- You have accessThe brain produces mind by modelingRichard M. Shiffrin, Danielle S. Bassett, Nikolaus Kriegeskorte, and Joshua B. TenenbaumPNAS November 24, 2020 117 (47) 29299-29301; first published November 23, 2020. https://doi.org/10.1073/pnas.1912340117
Colloquium Papers
- You have accessRapid trial-and-error learning with simulation supports flexible tool use and physical reasoningKelsey R. Allen, Kevin A. Smith, and Joshua B. TenenbaumPNAS November 24, 2020 117 (47) 29302-29310; first published November 23, 2020. https://doi.org/10.1073/pnas.1912341117
- You have accessRational thoughts in neural codesZhengwei Wu, Minhae Kwon, Saurabh Daptardar, Paul Schrater, and Xaq PitkowPNAS November 24, 2020 117 (47) 29311-29320; first published November 23, 2020. https://doi.org/10.1073/pnas.1912336117
- You have accessLow rank mechanisms underlying flexible visual representationsDouglas A. Ruff, Cheng Xue, Lily E. Kramer, Faisal Baqai, and Marlene R. CohenPNAS November 24, 2020 117 (47) 29321-29329; first published November 23, 2020. https://doi.org/10.1073/pnas.2005797117
- You have accessControversial stimuli: Pitting neural networks against each other as models of human cognitionTal Golan, Prashant C. Raju, and Nikolaus KriegeskortePNAS November 24, 2020 117 (47) 29330-29337; first published November 23, 2020. https://doi.org/10.1073/pnas.1912334117
- You have accessRepresentations of common event structure in medial temporal lobe and frontoparietal cortex support efficient inferenceNeal W Morton, Margaret L. Schlichting, and Alison R. PrestonPNAS November 24, 2020 117 (47) 29338-29345; first published November 23, 2020. https://doi.org/10.1073/pnas.1912338117
- You have accessAging and the encoding of changes in events: The role of neural activity pattern reinstatementDavid Stawarczyk, Christopher N. Wahlheim, Joset A. Etzel, Abraham Z. Snyder, and Jeffrey M. ZacksPNAS November 24, 2020 117 (47) 29346-29353; first published November 23, 2020. https://doi.org/10.1073/pnas.1918063117
- You have accessLarge-scale dissociations between views of objects, scenes, and reachable-scale environments in visual cortexEmilie L. Josephs and Talia KonklePNAS November 24, 2020 117 (47) 29354-29362; first published November 23, 2020. https://doi.org/10.1073/pnas.1912333117
- You have accessLocal reliability weighting explains identification of partially masked objects in natural imagesStephen Sebastian, Eric S. Seemiller, and Wilson S. GeislerPNAS November 24, 2020 117 (47) 29363-29370; first published November 23, 2020. https://doi.org/10.1073/pnas.1912331117
- You have accessFrom likely to likable: The role of statistical typicality in human social assessment of facesChaitanya K. Ryali, Stanny Goffin, Piotr Winkielman, and Angela J. YuPNAS November 24, 2020 117 (47) 29371-29380; first published November 23, 2020. https://doi.org/10.1073/pnas.1912343117
- You have accessComputational evidence for hierarchically structured reinforcement learning in humansMaria K. Eckstein and Anne G. E. CollinsPNAS November 24, 2020 117 (47) 29381-29389; first published November 23, 2020. https://doi.org/10.1073/pnas.1912330117
- You have accessAI, visual imagery, and a case study on the challenges posed by human intelligence testsMaithilee KundaPNAS November 24, 2020 117 (47) 29390-29397; first published November 23, 2020. https://doi.org/10.1073/pnas.1912335117
- You have accessGaussian process linking functions for mind, brain, and behaviorGiwon Bahg, Daniel G. Evans, Matthew Galdo, and Brandon M. TurnerPNAS November 24, 2020 117 (47) 29398-29406; first published November 23, 2020. https://doi.org/10.1073/pnas.1912342117
- You have accessHow humans learn and represent networksChristopher W. Lynn and Danielle S. BassettPNAS November 24, 2020 117 (47) 29407-29415; first published November 23, 2020. https://doi.org/10.1073/pnas.1912328117
Brief Reports
- Open AccessEvidence that coronavirus superspreading is fat-tailedFelix Wong and James J. CollinsPNAS November 24, 2020 117 (47) 29416-29418; first published November 2, 2020. https://doi.org/10.1073/pnas.2018490117
- Open AccessCOVID-19 pandemic impacts on global inland fisheriesGretchen L. Stokes, Abigail J. Lynch, Benjamin S. Lowe, Simon Funge-Smith, John Valbo‐Jørgensen, and Samuel J. SmidtPNAS November 24, 2020 117 (47) 29419-29421; first published November 2, 2020. https://doi.org/10.1073/pnas.2014016117
Physical Sciences
Applied Mathematics
- You have accessHow humans learn and represent networksChristopher W. Lynn and Danielle S. BassettPNAS November 24, 2020 117 (47) 29407-29415; first published November 23, 2020. https://doi.org/10.1073/pnas.1912328117
Applied Physical Sciences
- Open AccessCoupling of light and mechanics in a photonic crystal waveguideJ.-B. Béguin, Z. Qin, X. Luan, and H. J. KimblePNAS November 24, 2020 117 (47) 29422-29430; first published November 9, 2020. https://doi.org/10.1073/pnas.2014851117
- You have accessScaling confirmation of the thermodynamic dislocation theoryJ. S. Langer and K. C. LePNAS November 24, 2020 117 (47) 29431-29434; first published November 9, 2020. https://doi.org/10.1073/pnas.2018647117
Biophysics and Computational Biology
- Open AccessMaster curve of boosted diffusion for 10 catalytic enzymesAh-Young Jee, Tsvi Tlusty, and Steve GranickPNAS November 24, 2020 117 (47) 29435-29441; first published November 9, 2020. https://doi.org/10.1073/pnas.2019810117
See companion article:
- A thermodynamic perspective on enhanced enzyme diffusion- Dec 09, 2020
Chemistry
- Open AccessEnhanced and stabilized hydrogen production from methanol by ultrasmall Ni nanoclusters immobilized on defect-rich h-BN nanosheetsZhuolei Zhang, Ji Su, Ana Sanz Matias, Madeleine Gordon, Yi-Sheng Liu, Jinghua Guo, Chengyu Song, Chaochao Dun, David Prendergast, Gabor A. Somorjai, and Jeffrey J. UrbanPNAS November 24, 2020 117 (47) 29442-29452; first published November 9, 2020. https://doi.org/10.1073/pnas.2015897117
- You have accessUnderpotential lithium plating on graphite anodes caused by temperature heterogeneityHansen Wang, Yangying Zhu, Sang Cheol Kim, Allen Pei, Yanbin Li, David T. Boyle, Hongxia Wang, Zewen Zhang, Yusheng Ye, William Huang, Yayuan Liu, Jinwei Xu, Jun Li, Fang Liu, and Yi CuiPNAS November 24, 2020 117 (47) 29453-29461; first published November 9, 2020. https://doi.org/10.1073/pnas.2009221117
- Open AccessRegulating kinetics and thermodynamics of electrochemical nitrogen reduction with metal single-atom catalysts in a pressurized electrolyserHaiyuan Zou, Weifeng Rong, Shuting Wei, Yongfei Ji, and Lele DuanPNAS November 24, 2020 117 (47) 29462-29468; first published November 10, 2020. https://doi.org/10.1073/pnas.2015108117
- Open AccessStructure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation targetŁukasz F. Sobala, Pearl Z. Fernandes, Zalihe Hakki, Andrew J. Thompson, Jonathon D. Howe, Michelle Hill, Nicole Zitzmann, Scott Davies, Zania Stamataki, Terry D. Butters, Dominic S. Alonzi, Spencer J. Williams, and Gideon J. DaviesPNAS November 24, 2020 117 (47) 29595-29601; first published November 5, 2020. https://doi.org/10.1073/pnas.2013620117
Computer Sciences
- You have accessAI, visual imagery, and a case study on the challenges posed by human intelligence testsMaithilee KundaPNAS November 24, 2020 117 (47) 29390-29397; first published November 23, 2020. https://doi.org/10.1073/pnas.1912335117
Earth, Atmospheric, and Planetary Sciences
- Open AccessMercury isotopes identify near-surface marine mercury in deep-sea trench biota
- From the Cover
- Inaugural Article
Joel D. Blum, Jeffrey C. Drazen, Marcus W. Johnson, Brian N. Popp, Laura C. Motta, and Alan J. JamiesonPNAS November 24, 2020 117 (47) 29292-29298; first published November 16, 2020. https://doi.org/10.1073/pnas.2012773117See companion article:
- Profile of Joel D. Blum- Nov 23, 2020
- You have accessQuantification of organic aerosol and brown carbon evolution in fresh wildfire plumesBrett B. Palm, Qiaoyun Peng, Carley D. Fredrickson, Ben H. Lee, Lauren A. Garofalo, Matson A. Pothier, Sonia M. Kreidenweis, Delphine K. Farmer, Rudra P. Pokhrel, Yingjie Shen, Shane M. Murphy, Wade Permar, Lu Hu, Teresa L. Campos, Samuel R. Hall, Kirk Ullmann, Xuan Zhang, Frank Flocke, Emily V. Fischer, and Joel A. ThorntonPNAS November 24, 2020 117 (47) 29469-29477; first published November 4, 2020. https://doi.org/10.1073/pnas.2012218117
- You have accessRapid reductions and millennial-scale variability in Nordic Seas sea ice cover during abrupt glacial climate changesHenrik Sadatzki, Niccolò Maffezzoli, Trond M. Dokken, Margit H. Simon, Sarah M. P. Berben, Kirsten Fahl, Helle A. Kjær, Andrea Spolaor, Ruediger Stein, Paul Vallelonga, Bo M. Vinther, and Eystein JansenPNAS November 24, 2020 117 (47) 29478-29486; first published November 9, 2020. https://doi.org/10.1073/pnas.2005849117
- You have accessPaleocene latitude of the Kohistan–Ladakh arc indicates multistage India–Eurasia collisionCraig R. Martin, Oliver Jagoutz, Rajeev Upadhyay, Leigh H. Royden, Michael P. Eddy, Elizabeth Bailey, Claire I. O. Nichols, and Benjamin P. WeissPNAS November 24, 2020 117 (47) 29487-29494; first published November 4, 2020. https://doi.org/10.1073/pnas.2009039117
- You have accessIncreasing risk of another Cape Town “Day Zero” drought in the 21st centurySalvatore Pascale, Sarah B. Kapnick, Thomas L. Delworth, and William F. CookePNAS November 24, 2020 117 (47) 29495-29503; first published November 9, 2020. https://doi.org/10.1073/pnas.2009144117
- You have accessThe origin of secondary microseism Love wavesLucia Gualtieri, Etienne Bachmann, Frederik J. Simons, and Jeroen TrompPNAS November 24, 2020 117 (47) 29504-29511; first published November 9, 2020. https://doi.org/10.1073/pnas.2013806117
Engineering
- You have accessDual self-regulated delivery of insulin and glucagon by a hybrid patchZejun Wang, Jinqiang Wang, Hongjun Li, Jicheng Yu, Guojun Chen, Anna R. Kahkoska, Valerie Wu, Yi Zeng, Di Wen, Jayson R. Miedema, John B. Buse, and Zhen GuPNAS November 24, 2020 117 (47) 29512-29517; first published November 11, 2020. https://doi.org/10.1073/pnas.2011099117
- Open AccessElectric field-driven microfluidics for rapid CRISPR-based diagnostics and its application to detection of SARS-CoV-2Ashwin Ramachandran, Diego A. Huyke, Eesha Sharma, Malaya K. Sahoo, ChunHong Huang, Niaz Banaei, Benjamin A. Pinsky, and Juan G. SantiagoPNAS November 24, 2020 117 (47) 29518-29525; first published November 4, 2020. https://doi.org/10.1073/pnas.2010254117
Environmental Sciences
- Open AccessPotential for sustainable irrigation expansion in a 3 °C warmer climateLorenzo Rosa, Davide Danilo Chiarelli, Matteo Sangiorgio, Areidy Aracely Beltran-Peña, Maria Cristina Rulli, Paolo D’Odorico, and Inez FungPNAS November 24, 2020 117 (47) 29526-29534; first published November 9, 2020. https://doi.org/10.1073/pnas.2017796117
- You have accessThe quest for improved air quality may push China to continue its CO2 reduction beyond the Paris CommitmentJia Xing, Xi Lu, Shuxiao Wang, Tong Wang, Dian Ding, Sha Yu, Drew Shindell, Yang Ou, Lidia Morawska, Siwei Li, Lu Ren, Yuqiang Zhang, Dan Loughlin, Haotian Zheng, Bin Zhao, Shuchang Liu, Kirk R. Smith, and Jiming HaoPNAS November 24, 2020 117 (47) 29535-29542; first published November 9, 2020. https://doi.org/10.1073/pnas.2013297117
Physics
- You have accessSuperconductivity, correlated insulators, and Wess–Zumino–Witten terms in twisted bilayer grapheneMaine Christos, Subir Sachdev, and Mathias S. ScheurerPNAS November 24, 2020 117 (47) 29543-29554; first published November 9, 2020. https://doi.org/10.1073/pnas.2014691117
- You have accessQuantum spin-liquid states in an organic magnetic layer and molecular rotor hybridPéter Szirmai, Cécile Mézière, Guillaume Bastien, Pawel Wzietek, Patrick Batail, Edoardo Martino, Konstantins Mantulnikovs, Andrea Pisoni, Kira Riedl, Stephen Cottrell, Christopher Baines, László Forró, and Bálint NáfrádiPNAS November 24, 2020 117 (47) 29555-29560; first published November 5, 2020. https://doi.org/10.1073/pnas.2000188117
- Open AccessObservation of non-Hermitian topology and its bulk–edge correspondence in an active mechanical metamaterialAnanya Ghatak, Martin Brandenbourger, Jasper van Wezel, and Corentin CoulaisPNAS November 24, 2020 117 (47) 29561-29568; first published November 9, 2020. https://doi.org/10.1073/pnas.2010580117
Sustainability Science
- Open AccessMarine wild-capture fisheries after nuclear warKim J. N. Scherrer, Cheryl S. Harrison, Ryan F. Heneghan, Eric Galbraith, Charles G. Bardeen, Joshua Coupe, Jonas Jägermeyr, Nicole S. Lovenduski, August Luna, Alan Robock, Jessica Stevens, Samantha Stevenson, Owen B. Toon, and Lili XiaPNAS November 24, 2020 117 (47) 29748-29758; first published November 9, 2020. https://doi.org/10.1073/pnas.2008256117
Social Sciences
Anthropology
- You have accessEarly evidence for mounted horseback riding in northwest China
- From the Cover
Yue Li, Chengrui Zhang, William Timothy Treal Taylor, Liang Chen, Rowan K. Flad, Nicole Boivin, Huan Liu, Yue You, Jianxin Wang, Meng Ren, Tongyuan Xi, Yifu Han, Rui Wen, and Jian MaPNAS November 24, 2020 117 (47) 29569-29576; first published November 2, 2020. https://doi.org/10.1073/pnas.2004360117
Psychological and Cognitive Sciences
- You have accessRapid trial-and-error learning with simulation supports flexible tool use and physical reasoningKelsey R. Allen, Kevin A. Smith, and Joshua B. TenenbaumPNAS November 24, 2020 117 (47) 29302-29310; first published November 23, 2020. https://doi.org/10.1073/pnas.1912341117
- You have accessRational thoughts in neural codesZhengwei Wu, Minhae Kwon, Saurabh Daptardar, Paul Schrater, and Xaq PitkowPNAS November 24, 2020 117 (47) 29311-29320; first published November 23, 2020. https://doi.org/10.1073/pnas.1912336117
- You have accessAging and the encoding of changes in events: The role of neural activity pattern reinstatementDavid Stawarczyk, Christopher N. Wahlheim, Joset A. Etzel, Abraham Z. Snyder, and Jeffrey M. ZacksPNAS November 24, 2020 117 (47) 29346-29353; first published November 23, 2020. https://doi.org/10.1073/pnas.1918063117
- You have accessLocal reliability weighting explains identification of partially masked objects in natural imagesStephen Sebastian, Eric S. Seemiller, and Wilson S. GeislerPNAS November 24, 2020 117 (47) 29363-29370; first published November 23, 2020. https://doi.org/10.1073/pnas.1912331117
- You have accessFrom likely to likable: The role of statistical typicality in human social assessment of facesChaitanya K. Ryali, Stanny Goffin, Piotr Winkielman, and Angela J. YuPNAS November 24, 2020 117 (47) 29371-29380; first published November 23, 2020. https://doi.org/10.1073/pnas.1912343117
- You have accessComputational evidence for hierarchically structured reinforcement learning in humansMaria K. Eckstein and Anne G. E. CollinsPNAS November 24, 2020 117 (47) 29381-29389; first published November 23, 2020. https://doi.org/10.1073/pnas.1912330117
- You have accessAI, visual imagery, and a case study on the challenges posed by human intelligence testsMaithilee KundaPNAS November 24, 2020 117 (47) 29390-29397; first published November 23, 2020. https://doi.org/10.1073/pnas.1912335117
- You have accessGaussian process linking functions for mind, brain, and behaviorGiwon Bahg, Daniel G. Evans, Matthew Galdo, and Brandon M. TurnerPNAS November 24, 2020 117 (47) 29398-29406; first published November 23, 2020. https://doi.org/10.1073/pnas.1912342117
- You have accessHow humans learn and represent networksChristopher W. Lynn and Danielle S. BassettPNAS November 24, 2020 117 (47) 29407-29415; first published November 23, 2020. https://doi.org/10.1073/pnas.1912328117
Sustainability Science
- Open AccessHigh-resolution land value maps reveal underestimation of conservation costs in the United StatesChristoph NoltePNAS November 24, 2020 117 (47) 29577-29583; first published November 9, 2020. https://doi.org/10.1073/pnas.2012865117
Biological Sciences
Agricultural Sciences
- Open AccessPotential for sustainable irrigation expansion in a 3 °C warmer climateLorenzo Rosa, Davide Danilo Chiarelli, Matteo Sangiorgio, Areidy Aracely Beltran-Peña, Maria Cristina Rulli, Paolo D’Odorico, and Inez FungPNAS November 24, 2020 117 (47) 29526-29534; first published November 9, 2020. https://doi.org/10.1073/pnas.2017796117
Applied Biological Sciences
- You have accessDual self-regulated delivery of insulin and glucagon by a hybrid patchZejun Wang, Jinqiang Wang, Hongjun Li, Jicheng Yu, Guojun Chen, Anna R. Kahkoska, Valerie Wu, Yi Zeng, Di Wen, Jayson R. Miedema, John B. Buse, and Zhen GuPNAS November 24, 2020 117 (47) 29512-29517; first published November 11, 2020. https://doi.org/10.1073/pnas.2011099117
- You have accessA facile method of mapping HIV-1 neutralizing epitopes using chemically masked cysteines and deep sequencingRohini Datta, Rohan Roy Chowdhury, Kavyashree Manjunath, Luke Elizabeth Hanna, and Raghavan VaradarajanPNAS November 24, 2020 117 (47) 29584-29594; first published November 9, 2020. https://doi.org/10.1073/pnas.2010256117
Biochemistry
- Open AccessStructure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation targetŁukasz F. Sobala, Pearl Z. Fernandes, Zalihe Hakki, Andrew J. Thompson, Jonathon D. Howe, Michelle Hill, Nicole Zitzmann, Scott Davies, Zania Stamataki, Terry D. Butters, Dominic S. Alonzi, Spencer J. Williams, and Gideon J. DaviesPNAS November 24, 2020 117 (47) 29595-29601; first published November 5, 2020. https://doi.org/10.1073/pnas.2013620117
- Open AccessAssembly of the peripheral stalk of ATP synthase in human mitochondriaJiuya He, Joe Carroll, Shujing Ding, Ian M. Fearnley, Martin G. Montgomery, and John E. WalkerPNAS November 24, 2020 117 (47) 29602-29608; first published November 9, 2020. https://doi.org/10.1073/pnas.2017987117
- Open AccessReversing the direction of drug transport mediated by the human multidrug transporter P-glycoproteinAndaleeb Sajid, Sabrina Lusvarghi, Megumi Murakami, Eduardo E. Chufan, Biebele Abel, Michael M. Gottesman, Stewart R. Durell, and Suresh V. AmbudkarPNAS November 24, 2020 117 (47) 29609-29617; first published November 9, 2020. https://doi.org/10.1073/pnas.2016270117
- You have accessEvolution of insulin at the edge of foldability and its medical implicationsNischay K. Rege, Ming Liu, Yanwu Yang, Balamurugan Dhayalan, Nalinda P. Wickramasinghe, Yen-Shan Chen, Leili Rahimi, Huan Guo, Leena Haataja, Jinhong Sun, Faramarz Ismail-Beigi, Nelson B. Phillips, Peter Arvan, and Michael A. WeissPNAS November 24, 2020 117 (47) 29618-29628; first published November 5, 2020. https://doi.org/10.1073/pnas.2010908117
- Open AccessWater oxidation by photosystem II is the primary source of electrons for sustained H2 photoproduction in nutrient-replete green algaeSergey Kosourov, Valéria Nagy, Dmitry Shevela, Martina Jokel, Johannes Messinger, and Yagut AllahverdiyevaPNAS November 24, 2020 117 (47) 29629-29636; first published November 9, 2020. https://doi.org/10.1073/pnas.2009210117
- You have accessStructural and functional characterization of the pore-forming domain of pinholin S2168Lena M. E. Steger, Annika Kohlmeyer, Parvesh Wadhwani, Jochen Bürck, Erik Strandberg, Johannes Reichert, Stephan L. Grage, Sergii Afonin, Marin Kempfer, Anne C. Görner, Julia Koch, Torsten H. Walther, and Anne S. UlrichPNAS November 24, 2020 117 (47) 29637-29646; first published November 5, 2020. https://doi.org/10.1073/pnas.2007979117
- Open AccessThe 3 × 120° rotary mechanism of Paracoccus denitrificans F1-ATPase is different from that of the bacterial and mitochondrial F1-ATPasesMariel Zarco-Zavala, Ryo Watanabe, Duncan G. G. McMillan, Toshiharu Suzuki, Hiroshi Ueno, Francisco Mendoza-Hoffmann, José J. García-Trejo, and Hiroyuki NojiPNAS November 24, 2020 117 (47) 29647-29657; first published November 9, 2020. https://doi.org/10.1073/pnas.2003163117
- Open AccessA majority of Rhodobacter sphaeroides promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activationKemardo K. Henry, Wilma Ross, Kevin S. Myers, Kimberly C. Lemmer, Jessica M. Vera, Robert Landick, Timothy J. Donohue, and Richard L. GoursePNAS November 24, 2020 117 (47) 29658-29668; first published November 9, 2020. https://doi.org/10.1073/pnas.2010087117
- You have accessLipoteichoic acid polymer length is determined by competition between free starter unitsAnthony R. Hesser, Kaitlin Schaefer, Wonsik Lee, and Suzanne WalkerPNAS November 24, 2020 117 (47) 29669-29676; first published November 10, 2020. https://doi.org/10.1073/pnas.2008929117
Biophysics and Computational Biology
- Open AccessMaster curve of boosted diffusion for 10 catalytic enzymesAh-Young Jee, Tsvi Tlusty, and Steve GranickPNAS November 24, 2020 117 (47) 29435-29441; first published November 9, 2020. https://doi.org/10.1073/pnas.2019810117
See companion article:
- A thermodynamic perspective on enhanced enzyme diffusion- Dec 09, 2020
- You have accessMichler’s hydrol blue elucidates structural differences in prion strainsYiling Xiao, Sandra Rocha, Catherine C. Kitts, Anna Reymer, Tamás Beke-Somfai, Kendra K. Frederick, and Bengt NordénPNAS November 24, 2020 117 (47) 29677-29683; first published November 9, 2020. https://doi.org/10.1073/pnas.2001732117
- Open AccessDesigned nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cellsMatthias Barone, Matthias Müller, Slim Chiha, Jiang Ren, Dominik Albat, Arne Soicke, Stephan Dohmen, Marco Klein, Judith Bruns, Maarten van Dinther, Robert Opitz, Peter Lindemann, Monika Beerbaum, Kathrin Motzny, Yvette Roske, Peter Schmieder, Rudolf Volkmer, Marc Nazaré, Udo Heinemann, Hartmut Oschkinat, Peter ten Dijke, Hans-Günther Schmalz, and Ronald KühnePNAS November 24, 2020 117 (47) 29684-29690; first published November 12, 2020. https://doi.org/10.1073/pnas.2007213117
Cell Biology
- You have accessDegenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencingFrancesco Chemello, Zhaoning Wang, Hui Li, John R. McAnally, Ning Liu, Rhonda Bassel-Duby, and Eric N. OlsonPNAS November 24, 2020 117 (47) 29691-29701; first published November 4, 2020. https://doi.org/10.1073/pnas.2018391117
See companion article:
- Open AccessCorrelated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivoStephen D. Carter, João I. Mamede, Thomas J. Hope, and Grant J. JensenPNAS November 24, 2020 117 (47) 29702-29711; first published November 5, 2020. https://doi.org/10.1073/pnas.1920323117
- Open AccessAmmonium transporter expression in sperm of the disease vector Aedes aegypti mosquito influences male fertilityAndrea C. Durant and Andrew DoniniPNAS November 24, 2020 117 (47) 29712-29719; first published November 9, 2020. https://doi.org/10.1073/pnas.2011648117
Ecology
- Open AccessForest and woodland replacement patterns following drought-related mortalityEnric Batllori, Francisco Lloret, Tuomas Aakala, William R. L. Anderegg, Ermias Aynekulu, Devin P. Bendixsen, Abdallah Bentouati, Christof Bigler, C. John Burk, J. Julio Camarero, Michele Colangelo, Jonathan D. Coop, Roderick Fensham, M. Lisa Floyd, Lucía Galiano, Joseph L. Ganey, Patrick Gonzalez, Anna L. Jacobsen, Jeffrey Michael Kane, Thomas Kitzberger, Juan C. Linares, Suzanne B. Marchetti, George Matusick, Michael Michaelian, Rafael M. Navarro-Cerrillo, Robert Brandon Pratt, Miranda D. Redmond, Andreas Rigling, Francesco Ripullone, Gabriel Sangüesa-Barreda, Yamila Sasal, Sandra Saura-Mas, Maria Laura Suarez, Thomas T. Veblen, Albert Vilà-Cabrera, Caroline Vincke, and Ben ZeemanPNAS November 24, 2020 117 (47) 29720-29729; first published November 2, 2020. https://doi.org/10.1073/pnas.2002314117
- You have accessA climatic dipole drives short- and long-term patterns of postfire forest recovery in the western United StatesCaitlin E. Littlefield, Solomon Z. Dobrowski, John T. Abatzoglou, Sean A. Parks, and Kimberley T. DavisPNAS November 24, 2020 117 (47) 29730-29737; first published November 9, 2020. https://doi.org/10.1073/pnas.2007434117
- You have accessSeasonal and diel patterns of abundance and activity of viruses in the Red SeaGur Hevroni, José Flores-Uribe, Oded Béjà, and Alon PhilosofPNAS November 24, 2020 117 (47) 29738-29747; first published November 10, 2020. https://doi.org/10.1073/pnas.2010783117
Environmental Sciences
- Open AccessMarine wild-capture fisheries after nuclear warKim J. N. Scherrer, Cheryl S. Harrison, Ryan F. Heneghan, Eric Galbraith, Charles G. Bardeen, Joshua Coupe, Jonas Jägermeyr, Nicole S. Lovenduski, August Luna, Alan Robock, Jessica Stevens, Samantha Stevenson, Owen B. Toon, and Lili XiaPNAS November 24, 2020 117 (47) 29748-29758; first published November 9, 2020. https://doi.org/10.1073/pnas.2008256117
Evolution
- Open AccessExploitative leaders incite intergroup warfare in a social mammal
- From the Cover
Rufus A. Johnstone, Michael A. Cant, Dominic Cram, and Faye J. ThompsonPNAS November 24, 2020 117 (47) 29759-29766; first published November 9, 2020. https://doi.org/10.1073/pnas.2003745117See companion article:
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- You have accessSelection on phenotypic plasticity favors thermal canalizationErik I. Svensson, Miguel Gomez-Llano, and John T. WallerPNAS November 24, 2020 117 (47) 29767-29774; first published November 9, 2020. https://doi.org/10.1073/pnas.2012454117
Genetics
- You have accessThe evolutionary origin and domestication history of goldfish (Carassius auratus)
- From the Cover
Duo Chen, Qing Zhang, Weiqi Tang, Zhen Huang, Gang Wang, Yongjun Wang, Jiaxian Shi, Huimin Xu, Lianyu Lin, Zhen Li, Wenchao Chi, Likun Huang, Jing Xia, Xingtan Zhang, Lin Guo, Yuanyuan Wang, Panpan Ma, Juan Tang, Gang Zhou, Min Liu, Fuyan Liu, Xiuting Hua, Baiyu Wang, Qiaochu Shen, Qing Jiang, Jingxian Lin, Xuequn Chen, Hongbo Wang, Meijie Dou, Lei Liu, Haoran Pan, Yiying Qi, Bin Wu, Jingping Fang, Yitao Zhou, Wan Cen, Wenjin He, Qiujin Zhang, Ting Xue, Gang Lin, Wenchun Zhang, Zhongjian Liu, Liming Qu, Aiming Wang, Qichang Ye, Jianming Chen, Yanding Zhang, Ray Ming, Marc Van Montagu, Haibao Tang, Yves Van de Peer, Youqiang Chen, and Jisen ZhangPNAS November 24, 2020 117 (47) 29775-29785; first published November 2, 2020. https://doi.org/10.1073/pnas.2005545117 - Open AccessOncogenic allelic interaction in Xiphophorus highlights hybrid incompatibilityYuan Lu, Angel Sandoval, Sarah Voss, Zhao Lai, Susanne Kneitz, Will Boswell, Mikki Boswell, Markita Savage, Christi Walter, Wes Warren, Manfred Schartl, and Ronald WalterPNAS November 24, 2020 117 (47) 29786-29794; first published November 9, 2020. https://doi.org/10.1073/pnas.2010133117
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Immunology and Inflammation
- Open AccessStructure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharidePedro Henriques, Lucia Dello Iacono, Ana Gimeno, Alessia Biolchi, Maria Rosaria Romano, Ana Arda, Gonҫalo J. L. Bernardes, Jesus Jimenez-Barbero, Francesco Berti, Rino Rappuoli, and Roberto AdamoPNAS November 24, 2020 117 (47) 29795-29802; first published November 6, 2020. https://doi.org/10.1073/pnas.2011385117
- Open AccessIdentification of a brainstem locus that inhibits tumor necrosis factorAdam M. Kressel, Tea Tsaava, Yaakov A. Levine, Eric H. Chang, Meghan E. Addorisio, Qing Chang, Barry J. Burbach, Daniela Carnevale, Giuseppe Lembo, Anthony M. Zador, Ulf Andersson, Valentin A. Pavlov, Sangeeta S. Chavan, and Kevin J. TraceyPNAS November 24, 2020 117 (47) 29803-29810; first published November 9, 2020. https://doi.org/10.1073/pnas.2008213117
- You have accessType 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophagesAjay Suresh Akhade, Shaikh M. Atif, Bhavana S. Lakshmi, Neha Dikshit, Kelly T. Hughes, Ayub Qadri, and Naeha SubramanianPNAS November 24, 2020 117 (47) 29811-29822; first published November 11, 2020. https://doi.org/10.1073/pnas.2002747117
Medical Sciences
- You have accessExcess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1– and chemokines-mediated mechanismsYelena Kravtsova-Ivantsiv, Gilad Goldhirsh, Alexandra Ivantsiv, Ofer Ben Itzhak, Yong Tae Kwon, Eli Pikarsky, and Aaron CiechanoverPNAS November 24, 2020 117 (47) 29823-29831; first published November 9, 2020. https://doi.org/10.1073/pnas.2019604117
Microbiology
- Open AccessRapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infectionWei Li, Chuan Chen, Aleksandra Drelich, David R. Martinez, Lisa E. Gralinski, Zehua Sun, Alexandra Schäfer, Swarali S. Kulkarni, Xianglei Liu, Sarah R. Leist, Doncho V. Zhelev, Liyong Zhang, Ye-Jin Kim, Eric C. Peterson, Alex Conard, John W. Mellors, Chien-Te K. Tseng, Darryl Falzarano, Ralph S. Baric, and Dimiter S. DimitrovPNAS November 24, 2020 117 (47) 29832-29838; first published November 2, 2020. https://doi.org/10.1073/pnas.2010197117
- You have accessDiscovery of small-molecule inhibitors of multidrug-resistance plasmid maintenance using a high-throughput screening approachKatelyn E. Zulauf and James E. KirbyPNAS November 24, 2020 117 (47) 29839-29850; first published November 9, 2020. https://doi.org/10.1073/pnas.2005948117
- Open AccessStructure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesisHeddy Soufari, Florent Waltz, Camila Parrot, Stéphanie Durrieu-Gaillard, Anthony Bochler, Lauriane Kuhn, Marie Sissler, and Yaser HashemPNAS November 24, 2020 117 (47) 29851-29861; first published November 9, 2020. https://doi.org/10.1073/pnas.2011301117
- You have accessType I interferon remodels lysosome function and modifies intestinal epithelial defenseHailong Zhang, Abdelrahim Zoued, Xu Liu, Brandon Sit, and Matthew K. WaldorPNAS November 24, 2020 117 (47) 29862-29871; first published November 10, 2020. https://doi.org/10.1073/pnas.2010723117
Neuroscience
- You have accessRational thoughts in neural codesZhengwei Wu, Minhae Kwon, Saurabh Daptardar, Paul Schrater, and Xaq PitkowPNAS November 24, 2020 117 (47) 29311-29320; first published November 23, 2020. https://doi.org/10.1073/pnas.1912336117
- You have accessLow rank mechanisms underlying flexible visual representationsDouglas A. Ruff, Cheng Xue, Lily E. Kramer, Faisal Baqai, and Marlene R. CohenPNAS November 24, 2020 117 (47) 29321-29329; first published November 23, 2020. https://doi.org/10.1073/pnas.2005797117
- You have accessRepresentations of common event structure in medial temporal lobe and frontoparietal cortex support efficient inferenceNeal W Morton, Margaret L. Schlichting, and Alison R. PrestonPNAS November 24, 2020 117 (47) 29338-29345; first published November 23, 2020. https://doi.org/10.1073/pnas.1912338117
- You have accessAging and the encoding of changes in events: The role of neural activity pattern reinstatementDavid Stawarczyk, Christopher N. Wahlheim, Joset A. Etzel, Abraham Z. Snyder, and Jeffrey M. ZacksPNAS November 24, 2020 117 (47) 29346-29353; first published November 23, 2020. https://doi.org/10.1073/pnas.1918063117
- You have accessFrom likely to likable: The role of statistical typicality in human social assessment of facesChaitanya K. Ryali, Stanny Goffin, Piotr Winkielman, and Angela J. YuPNAS November 24, 2020 117 (47) 29371-29380; first published November 23, 2020. https://doi.org/10.1073/pnas.1912343117
- You have accessComputational evidence for hierarchically structured reinforcement learning in humansMaria K. Eckstein and Anne G. E. CollinsPNAS November 24, 2020 117 (47) 29381-29389; first published November 23, 2020. https://doi.org/10.1073/pnas.1912330117
- You have accessGaussian process linking functions for mind, brain, and behaviorGiwon Bahg, Daniel G. Evans, Matthew Galdo, and Brandon M. TurnerPNAS November 24, 2020 117 (47) 29398-29406; first published November 23, 2020. https://doi.org/10.1073/pnas.1912342117
- You have accessA modeling framework for adaptive lifelong learning with transfer and savings through gating in the prefrontal cortexBen Tsuda, Kay M. Tye, Hava T. Siegelmann, and Terrence J. SejnowskiPNAS November 24, 2020 117 (47) 29872-29882; first published November 5, 2020. https://doi.org/10.1073/pnas.2009591117
- You have accessNeuropsychological and neuropathological observations of a long-studied case of memory impairmentLarry R. Squire, Soyun Kim, Jennifer C. Frascino, Jacopo Annese, Jeffrey Bennett, Ricardo Insausti, and David G. AmaralPNAS November 24, 2020 117 (47) 29883-29893; first published November 9, 2020. https://doi.org/10.1073/pnas.2018960117
- You have accessDeafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 bindingXiaojie Yu, Qirui Zhao, Xiaofen Li, Yixuan Chen, Ye Tian, Shuang Liu, Wei Xiong, and Pingbo HuangPNAS November 24, 2020 117 (47) 29894-29903; first published November 9, 2020. https://doi.org/10.1073/pnas.2011147117
- You have accessReshaping circadian metabolism in the suprachiasmatic nucleus and prefrontal cortex by nutritional challengePaola Tognini, Muntaha Samad, Kenichiro Kinouchi, Yu Liu, Jean-Christophe Helbling, Marie-Pierre Moisan, Kristin L. Eckel-Mahan, Pierre Baldi, and Paolo Sassone-CorsiPNAS November 24, 2020 117 (47) 29904-29913; first published November 10, 2020. https://doi.org/10.1073/pnas.2016589117
- You have accessStac protein regulates release of neuropeptidesI-Uen Hsu, Jeremy W. Linsley, Xiaoli Zhang, Jade E. Varineau, Drew A. Berkhoudt, Lilly E. Reid, Miranda C. Lum, Allison M. Orzel, Ari Leflein, Haoxing Xu, Catherine A. Collins, Richard I. Hume, Edwin S. Levitan, and John Y. KuwadaPNAS November 24, 2020 117 (47) 29914-29924; first published November 9, 2020. https://doi.org/10.1073/pnas.2009224117
- Open AccessOscillations in the central brain of Drosophila are phase locked to attended visual featuresMartyna J. Grabowska, Rhiannon Jeans, James Steeves, and Bruno van SwinderenPNAS November 24, 2020 117 (47) 29925-29936; first published November 11, 2020. https://doi.org/10.1073/pnas.2010749117
- Open AccessThe potassium channel subunit Kvβ1 serves as a major control point for synaptic facilitationIn Ha Cho, Lauren C. Panzera, Morven Chin, Scott A. Alpizar, Genaro E. Olveda, Robert A. Hill, and Michael B. HoppaPNAS November 24, 2020 117 (47) 29937-29947; first published November 9, 2020. https://doi.org/10.1073/pnas.2000790117
- Open AccessCharacteristics of sequential activity in networks with temporally asymmetric Hebbian learningMaxwell Gillett, Ulises Pereira, and Nicolas BrunelPNAS November 24, 2020 117 (47) 29948-29958; first published November 11, 2020. https://doi.org/10.1073/pnas.1918674117
Pharmacology
- Open AccessStructural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonistTakahiro Kawai, Bingfa Sun, Hitoshi Yoshino, Dan Feng, Yoshiyuki Suzuki, Masanori Fukazawa, Shunsuke Nagao, David B. Wainscott, Aaron D. Showalter, Brian A. Droz, Tong Sun Kobilka, Matthew P. Coghlan, Francis S. Willard, Yoshiki Kawabe, Brian K. Kobilka, and Kyle W. SloopPNAS November 24, 2020 117 (47) 29959-29967; first published November 11, 2020. https://doi.org/10.1073/pnas.2014879117
Physiology
- You have accessSelectivity filter ion binding affinity determines inactivation in a potassium channelCéline Boiteux, David J. Posson, Toby W. Allen, and Crina M. NimigeanPNAS November 24, 2020 117 (47) 29968-29978; first published November 5, 2020. https://doi.org/10.1073/pnas.2009624117
Plant Biology
- You have accessRerouting of ribosomal proteins into splicing in plant organellesChuande Wang, Rachel Fourdin, Martine Quadrado, Céline Dargel-Graffin, Dimitri Tolleter, David Macherel, and Hakim MireauPNAS November 24, 2020 117 (47) 29979-29987; first published November 9, 2020. https://doi.org/10.1073/pnas.2004075117
Psychological and Cognitive Sciences
- You have accessControversial stimuli: Pitting neural networks against each other as models of human cognitionTal Golan, Prashant C. Raju, and Nikolaus KriegeskortePNAS November 24, 2020 117 (47) 29330-29337; first published November 23, 2020. https://doi.org/10.1073/pnas.1912334117
- You have accessLarge-scale dissociations between views of objects, scenes, and reachable-scale environments in visual cortexEmilie L. Josephs and Talia KonklePNAS November 24, 2020 117 (47) 29354-29362; first published November 23, 2020. https://doi.org/10.1073/pnas.1912333117
- You have accessLocal reliability weighting explains identification of partially masked objects in natural imagesStephen Sebastian, Eric S. Seemiller, and Wilson S. GeislerPNAS November 24, 2020 117 (47) 29363-29370; first published November 23, 2020. https://doi.org/10.1073/pnas.1912331117
Corrections
- You have accessCorrection for Polymenidou et al., Humoral immune response to native eukaryotic prion protein correlates with anti-prion protectionPNAS November 24, 2020 117 (47) 29988; first published November 9, 2020. https://doi.org/10.1073/pnas.2021354117
- You have accessCorrection for Huang et al., Mechanism of water extraction from gypsum rock by desert colonizing microorganismsPNAS November 24, 2020 117 (47) 29989; first published November 9, 2020. https://doi.org/10.1073/pnas.2021524117
- You have accessCorrection for Kossin et al., Global increase in major tropical cyclone exceedance probability over the past four decadesPNAS November 24, 2020 117 (47) 29990; first published November 9, 2020. https://doi.org/10.1073/pnas.2021573117
- You have accessCorrection for Goldstein and Lee, Demographic perspectives on the mortality of COVID-19 and other epidemicsPNAS November 24, 2020 117 (47) 29991; first published November 2, 2020. https://doi.org/10.1073/pnas.2021355117
Commentaries
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