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Table of Contents

December 01, 2020; vol. 117 no. 48

This Week in PNAS

This week's research highlights
  • You have access
    In This Issue
    PNAS December 1, 2020 117 (48) 29993-29994; https://doi.org/10.1073/iti4820117

Opinion

Leading scientists discuss current issues
  • You have access
    Opinion: Biodiversity conservation during a global crisis: Consequences and the way forward
    • Front Matter
    Alok Bang and Suvarna Khadakkar
    PNAS December 1, 2020 117 (48) 29995-29999; first published November 11, 2020. https://doi.org/10.1073/pnas.2021460117

Profile

The life and work of NAS members
  • You have access
    Profile of Joel D. Blum
    Jennifer Viegas
    PNAS December 1, 2020 117 (48) 30000-30002; first published November 23, 2020. https://doi.org/10.1073/pnas.2022416117

    See companion article:

    • Mercury isotopes identify near-surface marine mercury in deep-sea trench biota
      - Nov 16, 2020

Commentaries

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    Hippocampal plasticity may drive cocaine relapse
    Vanessa E. Lehmann and Paul J. Kenny
    PNAS December 1, 2020 117 (48) 30003-30005; first published November 16, 2020. https://doi.org/10.1073/pnas.2020202117

    See companion article:

    • Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence
      - Oct 05, 2020
  • You have access
    Are nearly free silanols a unifying structural determinant of silica particle toxicity?
    C. Jeffrey Brinker, Kimberly S. Butler, and Stephen H. Garofalini
    PNAS December 1, 2020 117 (48) 30006-30008; first published November 13, 2020. https://doi.org/10.1073/pnas.2021078117

    See companion article:

    • Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles
      - Oct 23, 2020
  • You have access
    In fatal COVID-19, the immune response can control the virus but kill the patient
    Arturo Casadevall and Liise-anne Pirofski
    PNAS December 1, 2020 117 (48) 30009-30011; first published November 11, 2020. https://doi.org/10.1073/pnas.2021128117

    See companion article:

    • Transcriptional and proteomic insights into the host response in fatal COVID-19 cases
      - Oct 20, 2020
  • You have access
    Hawks, Doves, and mongooses
    Michael L. Wilson
    PNAS December 1, 2020 117 (48) 30012-30013; first published November 13, 2020. https://doi.org/10.1073/pnas.2021188117

    See companion article:

    • Exploitative leaders incite intergroup warfare in a social mammal
      - Nov 09, 2020

Perspective

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    Ethics in field experimentation: A call to establish new standards to protect the public from unwanted manipulation and real harms
    Rose McDermott and Peter K. Hatemi
    PNAS December 1, 2020 117 (48) 30014-30021; first published November 23, 2020. https://doi.org/10.1073/pnas.2012021117

Letters

  • Open Access
    Aspect ratio dependence of the ultimate-state transition in turbulent thermal convection
    Xiaozhou He, Eberhard Bodenschatz, and Guenter Ahlers
    PNAS December 1, 2020 117 (48) 30022-30023; first published November 24, 2020. https://doi.org/10.1073/pnas.2007399117
  • You have access
    Reply to He et al.: The dependence of heat transport law on aspect ratio is still unclear
    Kartik P. Iyer, Janet D. Scheel, Jörg Schumacher, and Katepalli R. Sreenivasan
    PNAS December 1, 2020 117 (48) 30024; first published November 24, 2020. https://doi.org/10.1073/pnas.2007913117

    See companion article:

    • Classical 1/3 scaling of convection holds up to Ra = 1015
      - Mar 25, 2020
  • You have access
    Safety concerns regarding concomitant use of tocilizumab and glucocorticoids in COVID-19 patients
    Chengliang Yang, Elizabeth Liu, and Mingyao Liu
    PNAS December 1, 2020 117 (48) 30025-30026; first published November 12, 2020. https://doi.org/10.1073/pnas.2009253117
  • You have access
    Reply to Yang et al.: Tocilizumab treatment in COVID-19 patients needs the assessment of the disease severity and timely intervention
    Xiaoling Xu, Mingfeng Han, Tiantian Li, Wei Sun, Dongsheng Wang, Binqing Fu, Yonggang Zhou, Xiaohu Zheng, Yun Yang, Xiuyong Li, Xiaohua Zhang, Aijun Pan, and Haiming Wei
    PNAS December 1, 2020 117 (48) 30027-30028; first published November 12, 2020. https://doi.org/10.1073/pnas.2011616117

    See companion article:

    • Effective treatment of severe COVID-19 patients with tocilizumab
      - Apr 29, 2020

Colloquium on the Science of Deep Learning

  • Introduction

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      The science of deep learning
      • From the Cover
      Richard Baraniuk, David Donoho, and Matan Gavish
      PNAS December 1, 2020 117 (48) 30029-30032; first published November 23, 2020. https://doi.org/10.1073/pnas.2020596117
  • Colloquium Papers

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      The unreasonable effectiveness of deep learning in artificial intelligence
      Terrence J. Sejnowski
      PNAS December 1, 2020 117 (48) 30033-30038; first published January 28, 2020. https://doi.org/10.1073/pnas.1907373117
    • You have access
      Theoretical issues in deep networks
      Tomaso Poggio, Andrzej Banburski, and Qianli Liao
      PNAS December 1, 2020 117 (48) 30039-30045; first published June 9, 2020. https://doi.org/10.1073/pnas.1907369117
    • You have access
      Emergent linguistic structure in artificial neural networks trained by self-supervision
      Christopher D. Manning, Kevin Clark, John Hewitt, Urvashi Khandelwal, and Omer Levy
      PNAS December 1, 2020 117 (48) 30046-30054; first published June 3, 2020. https://doi.org/10.1073/pnas.1907367117
    • You have access
      The frontier of simulation-based inference
      Kyle Cranmer, Johann Brehmer, and Gilles Louppe
      PNAS December 1, 2020 117 (48) 30055-30062; first published May 29, 2020. https://doi.org/10.1073/pnas.1912789117
    • You have access
      Benign overfitting in linear regression
      Peter L. Bartlett, Philip M. Long, Gábor Lugosi, and Alexander Tsigler
      PNAS December 1, 2020 117 (48) 30063-30070; first published April 24, 2020. https://doi.org/10.1073/pnas.1907378117
    • You have access
      Understanding the role of individual units in a deep neural network
      David Bau, Jun-Yan Zhu, Hendrik Strobelt, Agata Lapedriza, Bolei Zhou, and Antonio Torralba
      PNAS December 1, 2020 117 (48) 30071-30078; first published September 1, 2020. https://doi.org/10.1073/pnas.1907375117
    • You have access
      Fast reinforcement learning with generalized policy updates
      André Barreto, Shaobo Hou, Diana Borsa, David Silver, and Doina Precup
      PNAS December 1, 2020 117 (48) 30079-30087; first published August 17, 2020. https://doi.org/10.1073/pnas.1907370117
    • You have access
      On instabilities of deep learning in image reconstruction and the potential costs of AI
      Vegard Antun, Francesco Renna, Clarice Poon, Ben Adcock, and Anders C. Hansen
      PNAS December 1, 2020 117 (48) 30088-30095; first published May 11, 2020. https://doi.org/10.1073/pnas.1907377117
    • You have access
      Algorithms as discrimination detectors
      Jon Kleinberg, Jens Ludwig, Sendhil Mullainathan, and Cass R. Sunstein
      PNAS December 1, 2020 117 (48) 30096-30100; first published July 28, 2020. https://doi.org/10.1073/pnas.1912790117

Brief Reports

  • Open Access
    The effect of tethering on the clearance rate of suspension-feeding plankton
    Anders Andersen and Thomas Kiørboe
    PNAS December 1, 2020 117 (48) 30101-30103; first published November 16, 2020. https://doi.org/10.1073/pnas.2017441117
  • Open Access
    The interplay of movement and spatiotemporal variation in transmission degrades pandemic control
    Nicholas Kortessis, Margaret W. Simon, Michael Barfield, Gregory E. Glass, Burton H. Singer, and Robert D. Holt
    PNAS December 1, 2020 117 (48) 30104-30106; first published November 10, 2020. https://doi.org/10.1073/pnas.2018286117

Physical Sciences

  • Applied Mathematics

    • You have access
      Theoretical issues in deep networks
      Tomaso Poggio, Andrzej Banburski, and Qianli Liao
      PNAS December 1, 2020 117 (48) 30039-30045; first published June 9, 2020. https://doi.org/10.1073/pnas.1907369117
    • You have access
      On instabilities of deep learning in image reconstruction and the potential costs of AI
      Vegard Antun, Francesco Renna, Clarice Poon, Ben Adcock, and Anders C. Hansen
      PNAS December 1, 2020 117 (48) 30088-30095; first published May 11, 2020. https://doi.org/10.1073/pnas.1907377117
  • Applied Physical Sciences

    • Open Access
      Hyperchromatic structural color for perceptually enhanced sensing by the naked eye
      Tahmid H. Talukdar, Bria McCoy, Sarah K. Timmins, Taufiquar Khan, and Judson D. Ryckman
      PNAS December 1, 2020 117 (48) 30107-30117; first published November 16, 2020. https://doi.org/10.1073/pnas.2009162117
    • You have access
      Heterogeneity in social and epidemiological factors determines the risk of measles outbreaks
      Paolo Bosetti, Piero Poletti, Massimo Stella, Bruno Lepri, Stefano Merler, and Manlio De Domenico
      PNAS December 1, 2020 117 (48) 30118-30125; first published November 17, 2020. https://doi.org/10.1073/pnas.1920986117
  • Biophysics and Computational Biology

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      Structure and regulation of the BsYetJ calcium channel in lipid nanodiscs
      Chieh-Chin Li, Te-Yu Kao, Chu-Chun Cheng, and Yun-Wei Chiang
      PNAS December 1, 2020 117 (48) 30126-30134; first published November 18, 2020. https://doi.org/10.1073/pnas.2014094117
    • Open Access
      Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA
      Fengwei Zheng, Roxana E. Georgescu, Huilin Li, and Michael E. O’Donnell
      PNAS December 1, 2020 117 (48) 30344-30353; first published November 17, 2020. https://doi.org/10.1073/pnas.2017637117
    • Open Access
      Replisome bypass of a protein-based R-loop block by Pif1
      Grant D. Schauer, Lisanne M. Spenkelink, Jacob S. Lewis, Olga Yurieva, Stefan H. Mueller, Antoine M. van Oijen, and Michael E. O’Donnell
      PNAS December 1, 2020 117 (48) 30354-30361; first published November 16, 2020. https://doi.org/10.1073/pnas.2020189117
    • Open Access
      Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
      Shane J. Caldwell, Ian C. Haydon, Nikoletta Piperidou, Po-Ssu Huang, Matthew J. Bick, H. Sebastian Sjöström, Donald Hilvert, David Baker, and Cathleen Zeymer
      PNAS December 1, 2020 117 (48) 30362-30369; first published November 17, 2020. https://doi.org/10.1073/pnas.2008535117
    • You have access
      An S/T motif controls reversible oligomerization of the Hsp40 chaperone DNAJB6b through subtle reorganization of a β sheet backbone
      Theodoros K. Karamanos, Vitali Tugarinov, and G. Marius Clore
      PNAS December 1, 2020 117 (48) 30441-30450; first published November 16, 2020. https://doi.org/10.1073/pnas.2020306117
    • You have access
      Markov state modeling reveals alternative unbinding pathways for peptide–MHC complexes
      Jayvee R. Abella, Dinler Antunes, Kyle Jackson, Gregory Lizée, Cecilia Clementi, and Lydia E. Kavraki
      PNAS December 1, 2020 117 (48) 30610-30618; first published November 12, 2020. https://doi.org/10.1073/pnas.2007246117
    • Open Access
      mGreenLantern: a bright monomeric fluorescent protein with rapid expression and cell filling properties for neuronal imaging
      Benjamin C. Campbell, Elisa M. Nabel, Mitchell H. Murdock, Cristina Lao-Peregrin, Pantelis Tsoulfas, Murray G. Blackmore, Francis S. Lee, Conor Liston, Hirofumi Morishita, and Gregory A. Petsko
      PNAS December 1, 2020 117 (48) 30710-30721; first published November 18, 2020. https://doi.org/10.1073/pnas.2000942117
  • Chemistry

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      Stable metal anodes enabled by a labile organic molecule bonded to a reduced graphene oxide aerogel
      Yue Gao, Daiwei Wang, Yun Kyung Shin, Zhifei Yan, Zhuo Han, Ke Wang, Md Jamil Hossain, Shuling Shen, Atif AlZahrani, Adri C. T. van Duin, Thomas E. Mallouk, and Donghai Wang
      PNAS December 1, 2020 117 (48) 30135-30141; first published November 16, 2020. https://doi.org/10.1073/pnas.2001837117
    • You have access
      A chemical dynamics study on the gas-phase formation of triplet and singlet C5H2 carbenes
      Chao He, Galiya R. Galimova, Yuheng Luo, Long Zhao, André K. Eckhardt, Rui Sun, Alexander M. Mebel, and Ralf I. Kaiser
      PNAS December 1, 2020 117 (48) 30142-30150; first published November 16, 2020. https://doi.org/10.1073/pnas.2019257117
    • You have access
      Absolute ion hydration free energy scale and the surface potential of water via quantum simulation
      Yu Shi and Thomas L. Beck
      PNAS December 1, 2020 117 (48) 30151-30158; first published November 17, 2020. https://doi.org/10.1073/pnas.2017214117
  • Computer Sciences

    • You have access
      The unreasonable effectiveness of deep learning in artificial intelligence
      Terrence J. Sejnowski
      PNAS December 1, 2020 117 (48) 30033-30038; first published January 28, 2020. https://doi.org/10.1073/pnas.1907373117
    • You have access
      Emergent linguistic structure in artificial neural networks trained by self-supervision
      Christopher D. Manning, Kevin Clark, John Hewitt, Urvashi Khandelwal, and Omer Levy
      PNAS December 1, 2020 117 (48) 30046-30054; first published June 3, 2020. https://doi.org/10.1073/pnas.1907367117
    • You have access
      Understanding the role of individual units in a deep neural network
      David Bau, Jun-Yan Zhu, Hendrik Strobelt, Agata Lapedriza, Bolei Zhou, and Antonio Torralba
      PNAS December 1, 2020 117 (48) 30071-30078; first published September 1, 2020. https://doi.org/10.1073/pnas.1907375117
    • You have access
      Fast reinforcement learning with generalized policy updates
      André Barreto, Shaobo Hou, Diana Borsa, David Silver, and Doina Precup
      PNAS December 1, 2020 117 (48) 30079-30087; first published August 17, 2020. https://doi.org/10.1073/pnas.1907370117
    • You have access
      Algorithms as discrimination detectors
      Jon Kleinberg, Jens Ludwig, Sendhil Mullainathan, and Cass R. Sunstein
      PNAS December 1, 2020 117 (48) 30096-30100; first published July 28, 2020. https://doi.org/10.1073/pnas.1912790117
  • Earth, Atmospheric, and Planetary Sciences

    • Open Access
      From particle attachment to space-filling coral skeletons
      Chang-Yu Sun, Cayla A. Stifler, Rajesh V. Chopdekar, Connor A. Schmidt, Ganesh Parida, Vanessa Schoeppler, Benjamin I. Fordyce, Jack H. Brau, Tali Mass, Sylvie Tambutté, and Pupa U. P. A. Gilbert
      PNAS December 1, 2020 117 (48) 30159-30170; first published November 13, 2020. https://doi.org/10.1073/pnas.2012025117
    • You have access
      Molecular and isotopic evidence reveals the end-Triassic carbon isotope excursion is not from massive exogenous light carbon
      Calum P. Fox, Xingqian Cui, Jessica H. Whiteside, Paul E. Olsen, Roger E. Summons, and Kliti Grice
      PNAS December 1, 2020 117 (48) 30171-30178; first published November 16, 2020. https://doi.org/10.1073/pnas.1917661117
    • You have access
      Solar geoengineering may not prevent strong warming from direct effects of CO2 on stratocumulus cloud cover
      Tapio Schneider, Colleen M. Kaul, and Kyle G. Pressel
      PNAS December 1, 2020 117 (48) 30179-30185; first published November 16, 2020. https://doi.org/10.1073/pnas.2003730117
  • Engineering

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      Dirac cones and chiral selection of elastic waves in a soft strip
      Maxime Lanoy, Fabrice Lemoult, Antonin Eddi, and Claire Prada
      PNAS December 1, 2020 117 (48) 30186-30190; first published November 18, 2020. https://doi.org/10.1073/pnas.2010812117
    • You have access
      Ionization behavior of nanoporous polyamide membranes
      Cody L. Ritt, Jay R. Werber, Mengyi Wang, Zhongyue Yang, Yumeng Zhao, Heather J. Kulik, and Menachem Elimelech
      PNAS December 1, 2020 117 (48) 30191-30200; first published November 12, 2020. https://doi.org/10.1073/pnas.2008421117
    • You have access
      Swimming microorganisms acquire optimal efficiency with multiple cilia
      Toshihiro Omori, Hiroaki Ito, and Takuji Ishikawa
      PNAS December 1, 2020 117 (48) 30201-30207; first published November 16, 2020. https://doi.org/10.1073/pnas.2011146117
    • You have access
      Constitutive relationship and governing physical properties for magnetophoresis
      Ayankola O. Ayansiji, Anish V. Dighe, Andreas A. Linninger, and Meenesh R. Singh
      PNAS December 1, 2020 117 (48) 30208-30214; first published November 17, 2020. https://doi.org/10.1073/pnas.2018568117
  • Physics

    • Open Access
      Critical point for Bose–Einstein condensation of excitons in graphite
      Jinhua Wang, Pan Nie, Xiaokang Li, Huakun Zuo, Benoît Fauqué, Zengwei Zhu, and Kamran Behnia
      PNAS December 1, 2020 117 (48) 30215-30219; first published November 16, 2020. https://doi.org/10.1073/pnas.2012811117
    • Open Access
      From antiferromagnetic and hidden order to Pauli paramagnetism in UM2Si2 compounds with 5f electron duality
      Andrea Amorese, Martin Sundermann, Brett Leedahl, Andrea Marino, Daisuke Takegami, Hlynur Gretarsson, Andrei Gloskovskii, Christoph Schlueter, Maurits W. Haverkort, Yingkai Huang, Maria Szlawska, Dariusz Kaczorowski, Sheng Ran, M. Brian Maple, Eric D. Bauer, Andreas Leithe-Jasper, Philipp Hansmann, Peter Thalmeier, Liu Hao Tjeng, and Andrea Severing
      PNAS December 1, 2020 117 (48) 30220-30227; first published November 17, 2020. https://doi.org/10.1073/pnas.2005701117
    • Open Access
      Flow-induced choking of a compliant Hele-Shaw cell
      Finn Box, Gunnar G. Peng, Draga Pihler-Puzović, and Anne Juel
      PNAS December 1, 2020 117 (48) 30228-30233; first published November 16, 2020. https://doi.org/10.1073/pnas.2008273117
    • You have access
      Machine-learning iterative calculation of entropy for physical systems
      Amit Nir, Eran Sela, Roy Beck, and Yohai Bar-Sinai
      PNAS December 1, 2020 117 (48) 30234-30240; first published November 19, 2020. https://doi.org/10.1073/pnas.2017042117
    • You have access
      Multiscale structural complexity of natural patterns
      Andrey A. Bagrov, Ilia A. Iakovlev, Askar A. Iliasov, Mikhail I. Katsnelson, and Vladimir V. Mazurenko
      PNAS December 1, 2020 117 (48) 30241-30251; first published November 18, 2020. https://doi.org/10.1073/pnas.2004976117
    • You have access
      Hidden symmetries generate rigid folding mechanisms in periodic origami
      James McInerney, Bryan Gin-ge Chen, Louis Theran, Christian D. Santangelo, and D. Zeb Rocklin
      PNAS December 1, 2020 117 (48) 30252-30259; first published November 16, 2020. https://doi.org/10.1073/pnas.2005089117
    • You have access
      Topological Weaire–Thorpe models of amorphous matter
      Quentin Marsal, Dániel Varjas, and Adolfo G. Grushin
      PNAS December 1, 2020 117 (48) 30260-30265; first published November 18, 2020. https://doi.org/10.1073/pnas.2007384117
  • Statistics

    • You have access
      The frontier of simulation-based inference
      Kyle Cranmer, Johann Brehmer, and Gilles Louppe
      PNAS December 1, 2020 117 (48) 30055-30062; first published May 29, 2020. https://doi.org/10.1073/pnas.1912789117
    • You have access
      Benign overfitting in linear regression
      Peter L. Bartlett, Philip M. Long, Gábor Lugosi, and Alexander Tsigler
      PNAS December 1, 2020 117 (48) 30063-30070; first published April 24, 2020. https://doi.org/10.1073/pnas.1907378117
    • Open Access
      Methods for correcting inference based on outcomes predicted by machine learning
      Siruo Wang, Tyler H. McCormick, and Jeffrey T. Leek
      PNAS December 1, 2020 117 (48) 30266-30275; first published November 18, 2020. https://doi.org/10.1073/pnas.2001238117
    • Open Access
      Estimating and forecasting spatial population dynamics of apex predators using transnational genetic monitoring
      Richard Bischof, Cyril Milleret, Pierre Dupont, Joseph Chipperfield, Mahdieh Tourani, Andrés Ordiz, Perry de Valpine, Daniel Turek, J. Andrew Royle, Olivier Gimenez, Øystein Flagstad, Mikael Åkesson, Linn Svensson, Henrik Brøseth, and Jonas Kindberg
      PNAS December 1, 2020 117 (48) 30531-30538; first published November 16, 2020. https://doi.org/10.1073/pnas.2011383117

Social Sciences

  • Anthropology

    • You have access
      Matriliny reverses gender disparities in inflammation and hypertension among the Mosuo of China
      Adam Z. Reynolds, Katherine Wander, Chun-Yi Sum, Mingjie Su, Melissa Emery Thompson, Paul L. Hooper, Hui Li, Mary K. Shenk, Kathrine E. Starkweather, Tami Blumenfield, and Siobhán M. Mattison
      PNAS December 1, 2020 117 (48) 30324-30327; first published November 16, 2020. https://doi.org/10.1073/pnas.2014403117
  • Psychological and Cognitive Sciences

    • Open Access
      Reconciling print-size and display-size constraints on reading
      • From the Cover
      Nilsu Atilgan, Ying-Zi Xiong, and Gordon E. Legge
      PNAS December 1, 2020 117 (48) 30276-30284; first published November 9, 2020. https://doi.org/10.1073/pnas.2007514117
  • Social Sciences

    • Open Access
      Network interventions for managing the COVID-19 pandemic and sustaining economy
      Akihiro Nishi, George Dewey, Akira Endo, Sophia Neman, Sage K. Iwamoto, Michael Y. Ni, Yusuke Tsugawa, Georgios Iosifidis, Justin D. Smith, and Sean D. Young
      PNAS December 1, 2020 117 (48) 30285-30294; first published November 11, 2020. https://doi.org/10.1073/pnas.2014297117

      See companion article:

      • Considering network interventions
        - Dec 21, 2020
    • Open Access
      The social patterning of autism diagnoses reversed in California between 1992 and 2018
      Alix S. Winter, Christine Fountain, Keely Cheslack-Postava, and Peter S. Bearman
      PNAS December 1, 2020 117 (48) 30295-30302; first published November 16, 2020. https://doi.org/10.1073/pnas.2015762117
    • Open Access
      The confidence gap predicts the gender pay gap among STEM graduates
      • From the Cover
      Adina D. Sterling, Marissa E. Thompson, Shiya Wang, Abisola Kusimo, Shannon Gilmartin, and Sheri Sheppard
      PNAS December 1, 2020 117 (48) 30303-30308; first published November 16, 2020. https://doi.org/10.1073/pnas.2010269117
    • You have access
      The changing geography of social mobility in the United States
      Dylan Shane Connor and Michael Storper
      PNAS December 1, 2020 117 (48) 30309-30317; first published November 16, 2020. https://doi.org/10.1073/pnas.2010222117
  • Sustainability Science

    • Open Access
      Consequences of seafood mislabeling for marine populations and fisheries management
      Kailin Kroetz, Gloria M. Luque, Jessica A. Gephart, Sunny L. Jardine, Patrick Lee, Katrina Chicojay Moore, Cassandra Cole, Andrew Steinkruger, and C. Josh Donlan
      PNAS December 1, 2020 117 (48) 30318-30323; first published November 16, 2020. https://doi.org/10.1073/pnas.2003741117

Biological Sciences

  • Anthropology

    • You have access
      Matriliny reverses gender disparities in inflammation and hypertension among the Mosuo of China
      Adam Z. Reynolds, Katherine Wander, Chun-Yi Sum, Mingjie Su, Melissa Emery Thompson, Paul L. Hooper, Hui Li, Mary K. Shenk, Kathrine E. Starkweather, Tami Blumenfield, and Siobhán M. Mattison
      PNAS December 1, 2020 117 (48) 30324-30327; first published November 16, 2020. https://doi.org/10.1073/pnas.2014403117
  • Applied Biological Sciences

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      Glutaric acid production by systems metabolic engineering of an l-lysine–overproducing Corynebacterium glutamicum
      Taehee Han, Gi Bae Kim, and Sang Yup Lee
      PNAS December 1, 2020 117 (48) 30328-30334; first published November 16, 2020. https://doi.org/10.1073/pnas.2017483117
    • You have access
      Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice
      Carlos Castaño, Mercedes Mirasierra, Mario Vallejo, Anna Novials, and Marcelina Párrizas
      PNAS December 1, 2020 117 (48) 30335-30343; first published November 16, 2020. https://doi.org/10.1073/pnas.2016112117
  • Biochemistry

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      Structure and regulation of the BsYetJ calcium channel in lipid nanodiscs
      Chieh-Chin Li, Te-Yu Kao, Chu-Chun Cheng, and Yun-Wei Chiang
      PNAS December 1, 2020 117 (48) 30126-30134; first published November 18, 2020. https://doi.org/10.1073/pnas.2014094117
    • Open Access
      Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA
      Fengwei Zheng, Roxana E. Georgescu, Huilin Li, and Michael E. O’Donnell
      PNAS December 1, 2020 117 (48) 30344-30353; first published November 17, 2020. https://doi.org/10.1073/pnas.2017637117
    • Open Access
      Replisome bypass of a protein-based R-loop block by Pif1
      Grant D. Schauer, Lisanne M. Spenkelink, Jacob S. Lewis, Olga Yurieva, Stefan H. Mueller, Antoine M. van Oijen, and Michael E. O’Donnell
      PNAS December 1, 2020 117 (48) 30354-30361; first published November 16, 2020. https://doi.org/10.1073/pnas.2020189117
    • Open Access
      Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
      Shane J. Caldwell, Ian C. Haydon, Nikoletta Piperidou, Po-Ssu Huang, Matthew J. Bick, H. Sebastian Sjöström, Donald Hilvert, David Baker, and Cathleen Zeymer
      PNAS December 1, 2020 117 (48) 30362-30369; first published November 17, 2020. https://doi.org/10.1073/pnas.2008535117
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      Structure-function analysis of microRNA 3′-end trimming by Nibbler
      Wei Xie, Ivica Sowemimo, Rippei Hayashi, Juncheng Wang, Thomas R. Burkard, Julius Brennecke, Stefan L. Ameres, and Dinshaw J. Patel
      PNAS December 1, 2020 117 (48) 30370-30379; first published November 16, 2020. https://doi.org/10.1073/pnas.2018156117
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      Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi
      Christopher Lim, Jason M. Berk, Alyssa Blaise, Josie Bircher, Anthony J. Koleske, Mark Hochstrasser, and Yong Xiong
      PNAS December 1, 2020 117 (48) 30380-30390; first published November 12, 2020. https://doi.org/10.1073/pnas.2018163117
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      NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B
      Qiang Luo, Baihui Wang, Zhen Wu, Wen Jiang, Yueyue Wang, Kangxi Du, Nana Zhou, Lina Zheng, Jianhua Gan, Wen-Hui Shen, Jinbiao Ma, and Aiwu Dong
      PNAS December 1, 2020 117 (48) 30391-30399; first published November 16, 2020. https://doi.org/10.1073/pnas.2011089117
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      FMRP links optimal codons to mRNA stability in neurons
      Huan Shu, Elisa Donnard, Botao Liu, Suna Jung, Ruijia Wang, and Joel D. Richter
      PNAS December 1, 2020 117 (48) 30400-30411; first published November 16, 2020. https://doi.org/10.1073/pnas.2009161117
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      Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B12
      Romila Mascarenhas, Markus Ruetz, Liam McDevitt, Markos Koutmos, and Ruma Banerjee
      PNAS December 1, 2020 117 (48) 30412-30422; first published November 16, 2020. https://doi.org/10.1073/pnas.2007332117
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      The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase
      Mirjana Lilic, James Chen, Hande Boyaci, Nathaniel Braffman, Elizabeth A. Hubin, Jennifer Herrmann, Rolf Müller, Rachel Mooney, Robert Landick, Seth A. Darst, and Elizabeth A. Campbell
      PNAS December 1, 2020 117 (48) 30423-30432; first published November 16, 2020. https://doi.org/10.1073/pnas.2013706117
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      Interface switch mediates signal transmission in a two-component system
      Mingxing Wang, Qiong Guo, Kongfu Zhu, Bo Fang, Yifan Yang, Maikun Teng, Xu Li, and Yuyong Tao
      PNAS December 1, 2020 117 (48) 30433-30440; first published November 16, 2020. https://doi.org/10.1073/pnas.1912080117
  • Biophysics and Computational Biology

    • Open Access
      From particle attachment to space-filling coral skeletons
      Chang-Yu Sun, Cayla A. Stifler, Rajesh V. Chopdekar, Connor A. Schmidt, Ganesh Parida, Vanessa Schoeppler, Benjamin I. Fordyce, Jack H. Brau, Tali Mass, Sylvie Tambutté, and Pupa U. P. A. Gilbert
      PNAS December 1, 2020 117 (48) 30159-30170; first published November 13, 2020. https://doi.org/10.1073/pnas.2012025117
    • You have access
      An S/T motif controls reversible oligomerization of the Hsp40 chaperone DNAJB6b through subtle reorganization of a β sheet backbone
      Theodoros K. Karamanos, Vitali Tugarinov, and G. Marius Clore
      PNAS December 1, 2020 117 (48) 30441-30450; first published November 16, 2020. https://doi.org/10.1073/pnas.2020306117
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      Biophysical analysis of the structural evolution of substrate specificity in RuBisCO
      Saroj Poudel, Douglas H. Pike, Hagai Raanan, Joshua A. Mancini, Vikas Nanda, Rosalind E. M. Rickaby, and Paul G. Falkowski
      PNAS December 1, 2020 117 (48) 30451-30457; first published November 16, 2020. https://doi.org/10.1073/pnas.2018939117
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      Structural basis for polarized elongation of actin filaments
      Vilmos Zsolnay, Harshwardhan H. Katkar, Steven Z. Chou, Thomas D. Pollard, and Gregory A. Voth
      PNAS December 1, 2020 117 (48) 30458-30464; first published November 16, 2020. https://doi.org/10.1073/pnas.2011128117
    • Open Access
      Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin
      Rachel Leicher, Eva J. Ge, Xingcheng Lin, Matthew J. Reynolds, Wenjun Xie, Thomas Walz, Bin Zhang, Tom W. Muir, and Shixin Liu
      PNAS December 1, 2020 117 (48) 30465-30475; first published November 18, 2020. https://doi.org/10.1073/pnas.2003395117
  • Cell Biology

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      Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies
      Rachel S. Gormal, Pranesh Padmanabhan, Ravikiran Kasula, Adekunle T. Bademosi, Sean Coakley, Jean Giacomotto, Ailisa Blum, Merja Joensuu, Tristan P. Wallis, Harriet P. Lo, Srikanth Budnar, James Rae, Charles Ferguson, Michele Bastiani, Walter G. Thomas, Els Pardon, Jan Steyaert, Alpha S. Yap, Geoffrey J. Goodhill, Massimo A. Hilliard, Robert G. Parton, and Frédéric A. Meunier
      PNAS December 1, 2020 117 (48) 30476-30487; first published November 19, 2020. https://doi.org/10.1073/pnas.2007443117
    • You have access
      FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis
      Cuicui Wang, Jie Shen, Jun Ying, Ding Xiao, and Regis J. O’Keefe
      PNAS December 1, 2020 117 (48) 30488-30497; first published November 16, 2020. https://doi.org/10.1073/pnas.2017056117
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      The Cockayne syndrome group A and B proteins are part of a ubiquitin–proteasome degradation complex regulating cell division
      Elena Paccosi, Federico Costanzo, Michele Costantino, Alessio Balzerano, Laura Monteonofrio, Silvia Soddu, Giorgio Prantera, Stefano Brancorsini, Jean-Marc Egly, and Luca Proietti-De-Santis
      PNAS December 1, 2020 117 (48) 30498-30508; first published November 16, 2020. https://doi.org/10.1073/pnas.2006543117
  • Developmental Biology

    • Open Access
      Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles
      Marc Fernandez-Guerrero, Nayuta Yakushiji-Kaminatsui, Lucille Lopez-Delisle, Sofía Zdral, Fabrice Darbellay, Rocío Perez-Gomez, Christopher Chase Bolt, Manuel A. Sanchez-Martin, Denis Duboule, and Marian A. Ros
      PNAS December 1, 2020 117 (48) 30509-30519; first published November 16, 2020. https://doi.org/10.1073/pnas.2011078117
    • You have access
      Rox8 promotes microRNA-dependent yki messenger RNA decay
      Xiaowei Guo, Yihao Sun, Taha Azad, H. J. Janse van Rensburg, Jingjing Luo, Shuai Yang, Peng Liu, Zhongwei Lv, Meixiao Zhan, Ligong Lu, Yingqun Zhou, Xianjue Ma, Xiaoping Zhang, Xiaolong Yang, and Lei Xue
      PNAS December 1, 2020 117 (48) 30520-30530; first published November 17, 2020. https://doi.org/10.1073/pnas.2013449117
  • Ecology

    • Open Access
      Estimating and forecasting spatial population dynamics of apex predators using transnational genetic monitoring
      Richard Bischof, Cyril Milleret, Pierre Dupont, Joseph Chipperfield, Mahdieh Tourani, Andrés Ordiz, Perry de Valpine, Daniel Turek, J. Andrew Royle, Olivier Gimenez, Øystein Flagstad, Mikael Åkesson, Linn Svensson, Henrik Brøseth, and Jonas Kindberg
      PNAS December 1, 2020 117 (48) 30531-30538; first published November 16, 2020. https://doi.org/10.1073/pnas.2011383117
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      Parental benefits and offspring costs reflect parent–offspring conflict over the age of fledging among songbirds
      Todd M. Jones, Jeffrey D. Brawn, Ian J. Ausprey, Andrew C. Vitz, Amanda D. Rodewald, Douglas W. Raybuck, Than J. Boves, Cameron J. Fiss, Darin J. McNeil, Scott H. Stoleson, Jeffery L. Larkin, W. Andrew Cox, Amy C. Schwarzer, Noah P. Horsley, Evalynn M. Trumbo, and Michael P. Ward
      PNAS December 1, 2020 117 (48) 30539-30546; first published November 16, 2020. https://doi.org/10.1073/pnas.2008955117
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      The impact of COVID-19 nonpharmaceutical interventions on the future dynamics of endemic infections
      Rachel E. Baker, Sang Woo Park, Wenchang Yang, Gabriel A. Vecchi, C. Jessica E. Metcalf, and Bryan T. Grenfell
      PNAS December 1, 2020 117 (48) 30547-30553; first published November 9, 2020. https://doi.org/10.1073/pnas.2013182117
  • Evolution

    • You have access
      Genomic islands of differentiation in a rapid avian radiation have been driven by recent selective sweeps
      Hussein A. Hejase, Ayelet Salman-Minkov, Leonardo Campagna, Melissa J. Hubisz, Irby J. Lovette, Ilan Gronau, and Adam Siepel
      PNAS December 1, 2020 117 (48) 30554-30565; first published November 16, 2020. https://doi.org/10.1073/pnas.2015987117
  • Genetics

    • You have access
      Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division
      John Michael Replogle, Wen Zhou, Adrianna E. Amaro, James M. McFarland, Mariana Villalobos-Ortiz, Jeremy Ryan, Anthony Letai, Omer Yilmaz, Jason Sheltzer, Stephen J. Lippard, Uri Ben-David, and Angelika Amon
      PNAS December 1, 2020 117 (48) 30566-30576; first published November 17, 2020. https://doi.org/10.1073/pnas.2009506117
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      Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation
      Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, and Valérie Borde
      PNAS December 1, 2020 117 (48) 30577-30588; first published November 16, 2020. https://doi.org/10.1073/pnas.2013012117
    • You have access
      A microbial metabolite synergizes with endogenous serotonin to trigger C. elegans reproductive behavior
      Yen-Chih Chen, Mohammad R. Seyedsayamdost, and Niels Ringstad
      PNAS December 1, 2020 117 (48) 30589-30598; first published November 16, 2020. https://doi.org/10.1073/pnas.2017918117
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      Incompatibility between proliferation and plant invasion is mediated by a regulator of appressorium formation in the corn smut fungus Ustilago maydis
      Antonio de la Torre, Sónia Castanheira, and José Pérez-Martín
      PNAS December 1, 2020 117 (48) 30599-30609; first published November 16, 2020. https://doi.org/10.1073/pnas.2006909117
  • Immunology and Inflammation

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      Markov state modeling reveals alternative unbinding pathways for peptide–MHC complexes
      Jayvee R. Abella, Dinler Antunes, Kyle Jackson, Gregory Lizée, Cecilia Clementi, and Lydia E. Kavraki
      PNAS December 1, 2020 117 (48) 30610-30618; first published November 12, 2020. https://doi.org/10.1073/pnas.2007246117
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      Leukotriene B4 licenses inflammasome activation to enhance skin host defense
      Ana Carolina Guerta Salina, Stephanie L. Brandt, Nathan Klopfenstein, Amondrea Blackman, Júlia Miranda Ribeiro Bazzano, Anderson Sá-Nunes, Nicole Byers-Glosson, Claudia Brodskyn, Natalia Machado Tavares, Icaro Bonyek Santos Da Silva, Alexandra I. Medeiros, and C. Henrique Serezani
      PNAS December 1, 2020 117 (48) 30619-30627; first published November 12, 2020. https://doi.org/10.1073/pnas.2002732117
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      TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation
      Ricardo A. Irizarry-Caro, Margaret M. McDaniel, Garrett R. Overcast, Viral G. Jain, Ty Dale Troutman, and Chandrashekhar Pasare
      PNAS December 1, 2020 117 (48) 30628-30638; first published November 16, 2020. https://doi.org/10.1073/pnas.2009778117
    • Open Access
      Aberrant expression of USF2 in refractory rheumatoid arthritis and its regulation of proinflammatory cytokines in Th17 cells
      Dan Hu, Emily C. Tjon, Karin M. Andersson, Gabriela M. Molica, Minh C. Pham, Brian Healy, Gopal Murugaiyan, Nathalie Pochet, Vijay K. Kuchroo, Maria I. Bokarewa, and Howard L. Weiner
      PNAS December 1, 2020 117 (48) 30639-30648; first published November 17, 2020. https://doi.org/10.1073/pnas.2007935117
    • You have access
      Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis
      Ruoyi Jiang, Kenneth B. Hoehn, Casey S. Lee, Minh C. Pham, Robert J. Homer, Frank C. Detterbeck, Inmaculada Aban, Leslie Jacobson, Angela Vincent, Richard J. Nowak, Henry J. Kaminski, Steven H. Kleinstein, and Kevin C. O’Connor
      PNAS December 1, 2020 117 (48) 30649-30660; first published November 16, 2020. https://doi.org/10.1073/pnas.2007206117

      See companion article:

      • Thymectomy and myasthenia gravis
        - Dec 03, 2020
  • Medical Sciences

    • Open Access
      Label-free adaptive optics imaging of human retinal macrophage distribution and dynamics
      Daniel X. Hammer, Anant Agrawal, Ricardo Villanueva, Osamah Saeedi, and Zhuolin Liu
      PNAS December 1, 2020 117 (48) 30661-30669; first published November 9, 2020. https://doi.org/10.1073/pnas.2010943117
    • Open Access
      Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma
      Olivera Grbovic-Huezo, Kenneth L. Pitter, Nicolas Lecomte, Joseph Saglimbeni, Gokce Askan, Matilda Holm, Jerry P. Melchor, Rohit Chandwani, Suhasini Joshi, Caj Haglund, Christine A. Iacobuzio-Donahue, Gabriela Chiosis, Tuomas Tammela, and Steven D. Leach
      PNAS December 1, 2020 117 (48) 30670-30678; first published November 16, 2020. https://doi.org/10.1073/pnas.1920240117
  • Microbiology

    • Open Access
      Analysis of genomic distributions of SARS-CoV-2 reveals a dominant strain type with strong allelic associations
      Hsin-Chou Yang, Chun-houh Chen, Jen-Hung Wang, Hsiao-Chi Liao, Chih-Ting Yang, Chia-Wei Chen, Yin-Chun Lin, Chiun-How Kao, Mei-Yeh Jade Lu, and James C. Liao
      PNAS December 1, 2020 117 (48) 30679-30686; first published November 12, 2020. https://doi.org/10.1073/pnas.2007840117
    • You have access
      The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses
      Stuart Weston, Lauren Baracco, Chloe Keller, Krystal Matthews, Marisa E. McGrath, James Logue, Janie Liang, Julie Dyall, Michael R. Holbrook, Lisa E. Hensley, Peter B. Jahrling, Wenbo Yu, Alexander D. MacKerell Jr, and Matthew B. Frieman
      PNAS December 1, 2020 117 (48) 30687-30698; first published November 12, 2020. https://doi.org/10.1073/pnas.2012939117
    • You have access
      Transcriptome-based design of antisense inhibitors potentiates carbapenem efficacy in CRE Escherichia coli
      Thomas R. Aunins, Keesha E. Erickson, and Anushree Chatterjee
      PNAS December 1, 2020 117 (48) 30699-30709; first published November 16, 2020. https://doi.org/10.1073/pnas.1922187117
  • Neuroscience

    • You have access
      The unreasonable effectiveness of deep learning in artificial intelligence
      Terrence J. Sejnowski
      PNAS December 1, 2020 117 (48) 30033-30038; first published January 28, 2020. https://doi.org/10.1073/pnas.1907373117
    • Open Access
      mGreenLantern: a bright monomeric fluorescent protein with rapid expression and cell filling properties for neuronal imaging
      Benjamin C. Campbell, Elisa M. Nabel, Mitchell H. Murdock, Cristina Lao-Peregrin, Pantelis Tsoulfas, Murray G. Blackmore, Francis S. Lee, Conor Liston, Hirofumi Morishita, and Gregory A. Petsko
      PNAS December 1, 2020 117 (48) 30710-30721; first published November 18, 2020. https://doi.org/10.1073/pnas.2000942117
    • Open Access
      Fast recovery of disrupted tip links induced by mechanical displacement of hair bundles
      R. G. Alonso, M. Tobin, P. Martin, and A. J. Hudspeth
      PNAS December 1, 2020 117 (48) 30722-30727; first published November 16, 2020. https://doi.org/10.1073/pnas.2016858117
    • You have access
      Evidence accumulation for value computation in the prefrontal cortex during decision making
      Zhongqiao Lin, Chechang Nie, Yuanfeng Zhang, Yang Chen, and Tianming Yang
      PNAS December 1, 2020 117 (48) 30728-30737; first published November 16, 2020. https://doi.org/10.1073/pnas.2019077117
    • You have access
      Maternally inherited peptides as strain-specific chemosignals
      Hideto Kaba, Hiroko Fujita, Takeshi Agatsuma, and Hiroaki Matsunami
      PNAS December 1, 2020 117 (48) 30738-30743; first published November 16, 2020. https://doi.org/10.1073/pnas.2014712117
    • Open Access
      Thirst recruits phasic dopamine signaling through subfornical organ neurons
      Ted M. Hsu, Paula Bazzino, Samantha J. Hurh, Vaibhav R. Konanur, Jamie D. Roitman, and Mitchell F. Roitman
      PNAS December 1, 2020 117 (48) 30744-30754; first published November 16, 2020. https://doi.org/10.1073/pnas.2009233117
  • Pharmacology

    • Open Access
      An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling
      Wonjo Jang, C. Elizabeth Adams, Heng Liu, Cheng Zhang, Finn Olav Levy, Kjetil Wessel Andressen, and Nevin A. Lambert
      PNAS December 1, 2020 117 (48) 30755-30762; first published November 16, 2020. https://doi.org/10.1073/pnas.2010801117
  • Physiology

    • You have access
      Dirac cones and chiral selection of elastic waves in a soft strip
      Maxime Lanoy, Fabrice Lemoult, Antonin Eddi, and Claire Prada
      PNAS December 1, 2020 117 (48) 30186-30190; first published November 18, 2020. https://doi.org/10.1073/pnas.2010812117
    • You have access
      Lack of adipocyte purinergic P2Y6 receptor greatly improves whole body glucose homeostasis
      Shanu Jain, Sai P. Pydi, Kiran S. Toti, Bernard Robaye, Marco Idzko, Oksana Gavrilova, Jürgen Wess, and Kenneth A. Jacobson
      PNAS December 1, 2020 117 (48) 30763-30774; first published November 16, 2020. https://doi.org/10.1073/pnas.2006578117
    • Open Access
      The intracellular Ca2+ release channel TRPML1 regulates lower urinary tract smooth muscle contractility
      • From the Cover
      Caoimhin S. Griffin, Michael G. Alvarado, Evan Yamasaki, Bernard T. Drumm, Vivek Krishnan, Sher Ali, Eleanor M. Nagle, Kenton M. Sanders, and Scott Earley
      PNAS December 1, 2020 117 (48) 30775-30786; first published November 16, 2020. https://doi.org/10.1073/pnas.2016959117

      See companion article:

      • Igniting Ca2+ sparks with TRPML1
        - Dec 01, 2020
    • You have access
      Allosteric modulation of alternatively spliced Ca2+-activated Cl− channels TMEM16A by PI(4,5)P2 and CaMKII
      Woori Ko, Seung-Ryoung Jung, Kwon-Woo Kim, Jun-Hee Yeon, Cheon-Gyu Park, Joo Hyun Nam, Bertil Hille, and Byung-Chang Suh
      PNAS December 1, 2020 117 (48) 30787-30798; first published November 16, 2020. https://doi.org/10.1073/pnas.2014520117
  • Plant Biology

    • You have access
      Broad noncoding transcription suggests genome surveillance by RNA polymerase V
      Masayuki Tsuzuki, Shriya Sethuraman, Adriana N. Coke, M. Hafiz Rothi, Alan P. Boyle, and Andrzej T. Wierzbicki
      PNAS December 1, 2020 117 (48) 30799-30804; first published November 16, 2020. https://doi.org/10.1073/pnas.2014419117
    • Open Access
      HOS15 is a transcriptional corepressor of NPR1-mediated gene activation of plant immunity
      Mingzhe Shen, Chae Jin Lim, Junghoon Park, Jeong Eun Kim, Dongwon Baek, Jaesung Nam, Sang Yeol Lee, Jose M. Pardo, Woe-Yeon Kim, David Mackey, and Dae-Jin Yun
      PNAS December 1, 2020 117 (48) 30805-30815; first published November 16, 2020. https://doi.org/10.1073/pnas.2016049117
    • You have access
      Dissection of the general two-step di-C-glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants
      Zi-Long Wang, Hao-Meng Gao, Shuang Wang, Meng Zhang, Kuan Chen, Ya-Qun Zhang, Hai-Dong Wang, Bo-Yun Han, Lu-Lu Xu, Tian-Qiao Song, Cai-Hong Yun, Xue Qiao, and Min Ye
      PNAS December 1, 2020 117 (48) 30816-30823; first published November 16, 2020. https://doi.org/10.1073/pnas.2012745117
  • Population Biology

    • Open Access
      Network interventions for managing the COVID-19 pandemic and sustaining economy
      Akihiro Nishi, George Dewey, Akira Endo, Sophia Neman, Sage K. Iwamoto, Michael Y. Ni, Yusuke Tsugawa, Georgios Iosifidis, Justin D. Smith, and Sean D. Young
      PNAS December 1, 2020 117 (48) 30285-30294; first published November 11, 2020. https://doi.org/10.1073/pnas.2014297117

      See companion article:

      • Considering network interventions
        - Dec 21, 2020
    • You have access
      Global associations between macronutrient supply and age-specific mortality
      Alistair M. Senior, Shinichi Nakagawa, David Raubenheimer, and Stephen J. Simpson
      PNAS December 1, 2020 117 (48) 30824-30835; first published November 16, 2020. https://doi.org/10.1073/pnas.2015058117
  • Psychological and Cognitive Sciences

    • You have access
      A source for awareness-dependent figure–ground segregation in human prefrontal cortex
      Ling Huang, Lijuan Wang, Wangming Shen, Mengsha Li, Shiyu Wang, Xiaotong Wang, Leslie G. Ungerleider, and Xilin Zhang
      PNAS December 1, 2020 117 (48) 30836-30847; first published November 16, 2020. https://doi.org/10.1073/pnas.1922832117
  • Systems Biology

    • You have access
      Mutation bias within oncogene families is related to proliferation-specific codon usage
      Hannah Benisty, Marc Weber, Xavier Hernandez-Alias, Martin H. Schaefer, and Luis Serrano
      PNAS December 1, 2020 117 (48) 30848-30856; first published November 16, 2020. https://doi.org/10.1073/pnas.2016119117

Corrections

  • You have access
    Correction for Li et al., Multiorbital charge-density wave excitations and concomitant phonon anomalies in Bi2Sr2LaCuO6+δ
    PNAS December 1, 2020 117 (48) 30857; first published November 16, 2020. https://doi.org/10.1073/pnas.2022009117
  • You have access
    Correction for Ahmad et al., Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule
    PNAS December 1, 2020 117 (48) 30858; first published November 9, 2020. https://doi.org/10.1073/pnas.2021828117
  • You have access
    Correction for Yaron et al., Forelimb force direction and magnitude independently controlled by spinal modules in the macaque
    PNAS December 1, 2020 117 (48) 30859; first published November 9, 2020. https://doi.org/10.1073/pnas.2022015117

SI Correction

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    Correction to Supporting Information for Morales-Castilla et al., Diversity buffers winegrowing regions from climate change losses
    PNAS December 1, 2020 117 (48) 30860; first published November 9, 2020. https://doi.org/10.1073/pnas.2019721117
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Proceedings of the National Academy of Sciences: 117 (48)
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