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Research Article

Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence

View ORCID ProfileKristbjorn O. Gudmundsson, View ORCID ProfileNhu Nguyen, Kevin Oakley, Yufen Han, Bjorg Gudmundsdottir, Pentao Liu, Lino Tessarollo, Nancy A. Jenkins, Neal G. Copeland, and View ORCID ProfileYang Du
  1. aDepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814;
  2. bCellular and Molecular Therapeutics Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20814;
  3. cSchool of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong;
  4. dMouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702;
  5. eDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030

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PNAS December 15, 2020 117 (50) 31945-31953; first published December 2, 2020; https://doi.org/10.1073/pnas.2017626117
Kristbjorn O. Gudmundsson
aDepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814;
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  • ORCID record for Kristbjorn O. Gudmundsson
Nhu Nguyen
aDepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814;
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  • ORCID record for Nhu Nguyen
Kevin Oakley
aDepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814;
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Yufen Han
aDepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814;
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Bjorg Gudmundsdottir
bCellular and Molecular Therapeutics Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20814;
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Pentao Liu
cSchool of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong;
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Lino Tessarollo
dMouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702;
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Nancy A. Jenkins
eDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030
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Neal G. Copeland
eDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030
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  • For correspondence: ncopeland1@mdanderson.org yang.du@usuhs.edu
Yang Du
aDepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814;
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  • ORCID record for Yang Du
  • For correspondence: ncopeland1@mdanderson.org yang.du@usuhs.edu
  1. Contributed by Neal G. Copeland, October 28, 2020 (sent for review August 20, 2020; reviewed by Adam N. Goldfarb and Paul Liu)

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Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence
Kristbjorn O. Gudmundsson, Nhu Nguyen, Kevin Oakley, Yufen Han, Bjorg Gudmundsdottir, Pentao Liu, Lino Tessarollo, Nancy A. Jenkins, Neal G. Copeland, Yang Du
Proceedings of the National Academy of Sciences Dec 2020, 117 (50) 31945-31953; DOI: 10.1073/pnas.2017626117

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Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence
Kristbjorn O. Gudmundsson, Nhu Nguyen, Kevin Oakley, Yufen Han, Bjorg Gudmundsdottir, Pentao Liu, Lino Tessarollo, Nancy A. Jenkins, Neal G. Copeland, Yang Du
Proceedings of the National Academy of Sciences Dec 2020, 117 (50) 31945-31953; DOI: 10.1073/pnas.2017626117
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Proceedings of the National Academy of Sciences: 117 (50)
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