Table of Contents

Research Articles

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  Restrictions on the use of antigenic peptides by the immune system.

  J C Howard

  PNAS May 1, 1993 90 (9) 3777-3779; https://doi.org/10.1073/pnas.90.9.3777
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  Induction of DNA rearrangement and transposition.

  P Deininger

  PNAS May 1, 1993 90 (9) 3780-3781; https://doi.org/10.1073/pnas.90.9.3780
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  External GTP alters the motility and elicits an oscillating membrane depolarization in Paramecium tetraurelia.

  K D Clark, T M Hennessey, and D L Nelson

  PNAS May 1, 1993 90 (9) 3782-3786; https://doi.org/10.1073/pnas.90.9.3782
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  Molecular diversity of Ca2+ channel alpha 1 subunits from the marine ray Discopyge ommata.

  W A Horne, P T Ellinor, I Inman, M Zhou, R W Tsien, and T L Schwarz

  PNAS May 1, 1993 90 (9) 3787-3791; https://doi.org/10.1073/pnas.90.9.3787
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  CD43, the major sialoglycoprotein of human leukocytes, is proteolytically cleaved from the surface of stimulated lymphocytes and granulocytes.

  V Bazil and J L Strominger

  PNAS May 1, 1993 90 (9) 3792-3796; https://doi.org/10.1073/pnas.90.9.3792
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  Evidence for covalent binding of acyl glucuronides to serum albumin via an imine mechanism as revealed by tandem mass spectrometry.

  A Ding, J C Ojingwa, A F McDonagh, A L Burlingame, and L Z Benet

  PNAS May 1, 1993 90 (9) 3797-3801; https://doi.org/10.1073/pnas.90.9.3797
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  Global solutions of the equations of elastodynamics of incompressible neo-Hookean materials.

  D G Ebin

  PNAS May 1, 1993 90 (9) 3802-3805; https://doi.org/10.1073/pnas.90.9.3802
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  Sequence-specific recognition of double helical RNA and RNA.DNA by triple helix formation.

  H Han and P B Dervan

  PNAS May 1, 1993 90 (9) 3806-3810; https://doi.org/10.1073/pnas.90.9.3806
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  Atomic force microscopy of biochemically tagged DNA.

  M N Murray, H G Hansma, M Bezanilla, T Sano, D F Ogletree, W Kolbe, C L Smith, C R Cantor, S Spengler, and P K Hansma

  PNAS May 1, 1993 90 (9) 3811-3814; https://doi.org/10.1073/pnas.90.9.3811
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  Actin is a surface component of calf pulmonary artery endothelial cells in culture.

  J Moroianu, J W Fett, J F Riordan, and B L Vallee

  PNAS May 1, 1993 90 (9) 3815-3819; https://doi.org/10.1073/pnas.90.9.3815
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  Expression of the Xenopus laevis prolactin and thyrotropin genes during metamorphosis.

  L Buckbinder and D D Brown

  PNAS May 1, 1993 90 (9) 3820-3824; https://doi.org/10.1073/pnas.90.9.3820
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  Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice.

  S Garofalo, M Metsäranta, J Ellard, C Smith, W Horton, E Vuorio, and B de Crombrugghe

  PNAS May 1, 1993 90 (9) 3825-3829; https://doi.org/10.1073/pnas.90.9.3825
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  A bacterially expressed single-chain Fv construct from the 2B4 T-cell receptor.

  I Kurucz, C R Jost, A J George, S M Andrew, and D M Segal

  PNAS May 1, 1993 90 (9) 3830-3834; https://doi.org/10.1073/pnas.90.9.3830
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  Predicting protein diffusion coefficients.

  D Brune and S Kim

  PNAS May 1, 1993 90 (9) 3835-3839; https://doi.org/10.1073/pnas.90.9.3835
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  Evidence for virus-encoded glycosylation specificity.

  I N Wang, Y Li, Q Que, M Bhattacharya, L C Lane, W G Chaney, and J L Van Etten

  PNAS May 1, 1993 90 (9) 3840-3844; https://doi.org/10.1073/pnas.90.9.3840
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  Purification of a galanin receptor from pig brain.

  Y Chen, A Fournier, A Couvineau, M Laburthe, and B Amiranoff

  PNAS May 1, 1993 90 (9) 3845-3849; https://doi.org/10.1073/pnas.90.9.3845
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  Synthesis of (1-->3), (1-->4)-beta-D-glucan in the Golgi apparatus of maize coleoptiles.

  D M Gibeaut and N C Carpita

  PNAS May 1, 1993 90 (9) 3850-3854; https://doi.org/10.1073/pnas.90.9.3850
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  Retroviral insertions into a herpesvirus are clustered at the junctions of the short repeat and short unique sequences.

  D Jones, R Isfort, R Witter, R Kost, and H J Kung

  PNAS May 1, 1993 90 (9) 3855-3859; https://doi.org/10.1073/pnas.90.9.3855
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  Long-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioates.

  J Lisziewicz, D Sun, V Metelev, P Zamecnik, R C Gallo, and S Agrawal

  PNAS May 1, 1993 90 (9) 3860-3864; https://doi.org/10.1073/pnas.90.9.3860
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  Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters.

  D Melloul, Y Ben-Neriah, and E Cerasi

  PNAS May 1, 1993 90 (9) 3865-3869; https://doi.org/10.1073/pnas.90.9.3865
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  Initial localization of regulatory regions of the cardiac sarcolemmal Na(+)-Ca2+ exchanger.

  S Matsuoka, D A Nicoll, R F Reilly, D W Hilgemann, and K D Philipson

  PNAS May 1, 1993 90 (9) 3870-3874; https://doi.org/10.1073/pnas.90.9.3870
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  Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein.

  K Umezu, N W Chi, and R D Kolodner

  PNAS May 1, 1993 90 (9) 3875-3879; https://doi.org/10.1073/pnas.90.9.3875
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  Protein kinase A activation of glucocorticoid-mediated signaling in the developing retina.

  H Zhang, Y C Li, and A P Young

  PNAS May 1, 1993 90 (9) 3880-3884; https://doi.org/10.1073/pnas.90.9.3880
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  A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate.

  Z Wei, S J Swiedler, M Ishihara, A Orellana, and C B Hirschberg

  PNAS May 1, 1993 90 (9) 3885-3888; https://doi.org/10.1073/pnas.90.9.3885
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  Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury.

  M Marikovsky, K Breuing, P Y Liu, E Eriksson, S Higashiyama, P Farber, J Abraham, and M Klagsbrun

  PNAS May 1, 1993 90 (9) 3889-3893; https://doi.org/10.1073/pnas.90.9.3889
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  Retinoic acid is a negative regulator of the Epstein-Barr virus protein (BZLF1) that mediates disruption of latent infection.

  N D Sista, J S Pagano, W Liao, and S Kenney

  PNAS May 1, 1993 90 (9) 3894-3898; https://doi.org/10.1073/pnas.90.9.3894
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  Indirect autoregulation of a homeotic Drosophila gene mediated by extracellular signaling.

  F Thüringer and M Bienz

  PNAS May 1, 1993 90 (9) 3899-3903; https://doi.org/10.1073/pnas.90.9.3899
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  Tandem double CC-->TT mutations are produced by reactive oxygen species.

  T M Reid and L A Loeb

  PNAS May 1, 1993 90 (9) 3904-3907; https://doi.org/10.1073/pnas.90.9.3904
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  Expression of gonadotropin-releasing hormone receptors and autocrine regulation of neuropeptide release in immortalized hypothalamic neurons.

  L Z Krsmanović, S S Stojilković, L M Mertz, M Tomić, and K J Catt

  PNAS May 1, 1993 90 (9) 3908-3912; https://doi.org/10.1073/pnas.90.9.3908
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  Mice lacking major histocompatibility complex class I and class II molecules.

  M J Grusby, H Auchincloss Jr, R Lee, R S Johnson, J P Spencer, M Zijlstra, R Jaenisch, V E Papaioannou, and L H Glimcher

  PNAS May 1, 1993 90 (9) 3913-3917; https://doi.org/10.1073/pnas.90.9.3913
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  Histone H1 deposition and histone-DNA interactions in replicating chromatin.

  S Bavykin, L Srebreva, T Banchev, R Tsanev, J Zlatanova, and A Mirzabekov

  PNAS May 1, 1993 90 (9) 3918-3922; https://doi.org/10.1073/pnas.90.9.3918
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  In vivo expression of mutant preproendothelins: hierarchy of processing events but no strict requirement of Trp-Val at the processing site.

  M S Fabbrini, A Vitale, E Pedrazzini, G Nitti, M Zamai, M Tamburin, V R Caiolfa, C Patrono, and L Benatti

  PNAS May 1, 1993 90 (9) 3923-3927; https://doi.org/10.1073/pnas.90.9.3923
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  A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer.

  A Madan and P T Curtin

  PNAS May 1, 1993 90 (9) 3928-3932; https://doi.org/10.1073/pnas.90.9.3928
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  Increased intracellular Ca2+: a critical link in the pathophysiology of sepsis?

  S K Song, I E Karl, J J Ackerman, and R S Hotchkiss

  PNAS May 1, 1993 90 (9) 3933-3937; https://doi.org/10.1073/pnas.90.9.3933
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  Molecular cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger (NHE-2).

  J F Collins, T Honda, S Knobel, N M Bulus, J Conary, R DuBois, and F K Ghishan

  PNAS May 1, 1993 90 (9) 3938-3942; https://doi.org/10.1073/pnas.90.9.3938
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  Vascular cell adhesion molecule 1: contrasting transcriptional control mechanisms in muscle and endothelium.

  M F Iademarco, J J McQuillan, and D C Dean

  PNAS May 1, 1993 90 (9) 3943-3947; https://doi.org/10.1073/pnas.90.9.3943
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  Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

  D E Clevidence, D G Overdier, W Tao, X Qian, L Pani, E Lai, and R H Costa

  PNAS May 1, 1993 90 (9) 3948-3952; https://doi.org/10.1073/pnas.90.9.3948
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  Oltipraz, an inhibitor of human immunodeficiency virus type 1 replication.

  H J Prochaska, Y Yeh, P Baron, and B Polsky

  PNAS May 1, 1993 90 (9) 3953-3957; https://doi.org/10.1073/pnas.90.9.3953
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  High-resolution mapping of the HyHEL-10 epitope of chicken lysozyme by site-directed mutagenesis.

  L N Kam-Morgan, S J Smith-Gill, M G Taylor, L Zhang, A C Wilson, and J F Kirsch

  PNAS May 1, 1993 90 (9) 3958-3962; https://doi.org/10.1073/pnas.90.9.3958
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  Ligand-dependent transformation by the receptor for human granulocyte/macrophage colony-stimulating factor and tyrosine phosphorylation of the receptor beta subunit.

  L B Areces, M Jücker, J A San Miguel, A Mui, A Miyajima, and R A Feldman

  PNAS May 1, 1993 90 (9) 3963-3967; https://doi.org/10.1073/pnas.90.9.3963
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  Irish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phosphodiesterase beta-subunit gene.

  M L Suber, S J Pittler, N Qin, G C Wright, V Holcombe, R H Lee, C M Craft, R N Lolley, W Baehr, and R L Hurwitz

  PNAS May 1, 1993 90 (9) 3968-3972; https://doi.org/10.1073/pnas.90.9.3968
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  Evidence that the putative COOH-terminal signal transamidase involved in glycosylphosphatidylinositol protein synthesis is present in the endoplasmic reticulum.

  R Amthauer, K Kodukula, L Gerber, and S Udenfriend

  PNAS May 1, 1993 90 (9) 3973-3977; https://doi.org/10.1073/pnas.90.9.3973
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  A polypeptide bound by the chaperonin groEL is localized within a central cavity.

  K Braig, M Simon, F Furuya, J F Hainfeld, and A L Horwich

  PNAS May 1, 1993 90 (9) 3978-3982; https://doi.org/10.1073/pnas.90.9.3978
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  Evidence from in vitro replication that O6-methylguanine can adopt multiple conformations.

  M K Dosanjh, E L Loechler, and B Singer

  PNAS May 1, 1993 90 (9) 3983-3987; https://doi.org/10.1073/pnas.90.9.3983
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  Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage.

  T D Kessis, R J Slebos, W G Nelson, M B Kastan, B S Plunkett, S M Han, A T Lorincz, L Hedrick, and K R Cho

  PNAS May 1, 1993 90 (9) 3988-3992; https://doi.org/10.1073/pnas.90.9.3988
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  Missense mutations in the beta-myosin heavy-chain gene cause central core disease in hypertrophic cardiomyopathy.

  L Fananapazir, M C Dalakas, F Cyran, G Cohn, and N D Epstein

  PNAS May 1, 1993 90 (9) 3993-3997; https://doi.org/10.1073/pnas.90.9.3993
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  Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitro.

  W L Beatty, G I Byrne, and R P Morrison

  PNAS May 1, 1993 90 (9) 3998-4002; https://doi.org/10.1073/pnas.90.9.3998
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  Assembly of pericellular matrices by COS-7 cells transfected with CD44 lymphocyte-homing receptor genes.

  W Knudson, E Bartnik, and C B Knudson

  PNAS May 1, 1993 90 (9) 4003-4007; https://doi.org/10.1073/pnas.90.9.4003
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  Increasing the chemical potential of the germ-line antibody repertoire.

  N Sarvetnick, D Gurushanthaiah, N Han, J Prudent, P Schultz, and R Lerner

  PNAS May 1, 1993 90 (9) 4008-4011; https://doi.org/10.1073/pnas.90.9.4008
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  Thymidine kinase mutants obtained by random sequence selection.

  K M Munir, D C French, and L A Loeb

  PNAS May 1, 1993 90 (9) 4012-4016; https://doi.org/10.1073/pnas.90.9.4012
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  A protein phosphatase related to the vaccinia virus VH1 is encoded in the genomes of several orthopoxviruses and a baculovirus.

  D J Hakes, K J Martell, W G Zhao, R F Massung, J J Esposito, and J E Dixon

  PNAS May 1, 1993 90 (9) 4017-4021; https://doi.org/10.1073/pnas.90.9.4017
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  Characterization of the rat neutral and basic amino acid transporter utilizing anti-peptide antibodies.

  R Mosckovitz, N Yan, E Heimer, A Felix, S S Tate, and S Udenfriend

  PNAS May 1, 1993 90 (9) 4022-4026; https://doi.org/10.1073/pnas.90.9.4022
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  The TFIIIB-assembling subunit of yeast transcription factor TFIIIC has both tetratricopeptide repeats and basic helix-loop-helix motifs.

  C Marck, O Lefebvre, C Carles, M Riva, N Chaussivert, A Ruet, and A Sentenac

  PNAS May 1, 1993 90 (9) 4027-4031; https://doi.org/10.1073/pnas.90.9.4027
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  Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.

  L M Wang, A D Keegan, W Li, G E Lienhard, S Pacini, J S Gutkind, M G Myers Jr, X J Sun, M F White, and S A Aaronson

  PNAS May 1, 1993 90 (9) 4032-4036; https://doi.org/10.1073/pnas.90.9.4032
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  Genetic and molecular characterization of a Notch mutation in its Delta- and Serrate-binding domain in Drosophila.

  J F de Celis, R Barrio, A del Arco, and A García-Bellido

  PNAS May 1, 1993 90 (9) 4037-4041; https://doi.org/10.1073/pnas.90.9.4037
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  Arachidonic acid stimulates glucose uptake in cerebral cortical astrocytes.

  N Yu, J L Martin, N Stella, and P J Magistretti

  PNAS May 1, 1993 90 (9) 4042-4046; https://doi.org/10.1073/pnas.90.9.4042
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  Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells.

  U Kersting, D Kersting, and K R Spring

  PNAS May 1, 1993 90 (9) 4047-4051; https://doi.org/10.1073/pnas.90.9.4047
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  Opiate receptor agonists regulate phosphorylation of synapsin I in cocultures of rat spinal cord and dorsal root ganglion.

  S Y Nah, D Saya, J Barg, and Z Vogel

  PNAS May 1, 1993 90 (9) 4052-4056; https://doi.org/10.1073/pnas.90.9.4052
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  Cell type-preferred expression of maize cab-m1: repression in bundle sheath cells and enhancement in mesophyll cells.

  K C Bansal and L Bogorad

  PNAS May 1, 1993 90 (9) 4057-4061; https://doi.org/10.1073/pnas.90.9.4057
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  Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.

  B D Carter and F Medzihradsky

  PNAS May 1, 1993 90 (9) 4062-4066; https://doi.org/10.1073/pnas.90.9.4062
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  Saturation mutagenesis of the human interleukin 6 receptor-binding site: implications for its three-dimensional structure.

  R Savino, A Lahm, M Giorgio, A Cabibbo, A Tramontano, and G Ciliberto

  PNAS May 1, 1993 90 (9) 4067-4071; https://doi.org/10.1073/pnas.90.9.4067
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  Photoisomerization mechanism of the rhodopsin chromophore: picosecond photolysis of pigment containing 11-cis-locked eight-membered ring retinal.

  T Mizukami, H Kandori, Y Shichida, A H Chen, F Derguini, C G Caldwell, C F Biffe, K Nakanishi, and T Yoshizawa

  PNAS May 1, 1993 90 (9) 4072-4076; https://doi.org/10.1073/pnas.90.9.4072
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  Epitope-tagged Gq alpha subunits: expression of GTPase-deficient alpha subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetylcholine receptor.

  N X Qian, S Winitz, and G L Johnson

  PNAS May 1, 1993 90 (9) 4077-4081; https://doi.org/10.1073/pnas.90.9.4077
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  Identification of a cell line that expresses a cell surface and a soluble form of the gp330/receptor-associated protein (RAP) Heymann nephritis antigenic complex.

  R A Orlando and M G Farquhar

  PNAS May 1, 1993 90 (9) 4082-4086; https://doi.org/10.1073/pnas.90.9.4082
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  Body size, metabolic rate, generation time, and the molecular clock.

  A P Martin and S R Palumbi

  PNAS May 1, 1993 90 (9) 4087-4091; https://doi.org/10.1073/pnas.90.9.4087
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  Evasion of protective immunity by Borrelia burgdorferi by truncation of outer surface protein B.

  E Fikrig, H Tao, F S Kantor, S W Barthold, and R A Flavell

  PNAS May 1, 1993 90 (9) 4092-4096; https://doi.org/10.1073/pnas.90.9.4092
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  Transcriptional activation of low density lipoprotein receptor gene by angiotensin-converting enzyme inhibitors and Ca(2+)-channel blockers involves protein kinase C isoforms.

  L H Block, R Keul, M Crabos, R Ziesche, and M Roth

  PNAS May 1, 1993 90 (9) 4097-4101; https://doi.org/10.1073/pnas.90.9.4097
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  Isolation and sequence of a cDNA encoding the Jerusalem artichoke cinnamate 4-hydroxylase, a major plant cytochrome P450 involved in the general phenylpropanoid pathway.

  H G Teutsch, M P Hasenfratz, A Lesot, C Stoltz, J M Garnier, J M Jeltsch, F Durst, and D Werck-Reichhart

  PNAS May 1, 1993 90 (9) 4102-4106; https://doi.org/10.1073/pnas.90.9.4102
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  Expression of functional hepatitis B virus polymerase in yeast reveals it to be the sole viral protein required for correct initiation of reverse transcription.

  J E Tavis and D Ganem

  PNAS May 1, 1993 90 (9) 4107-4111; https://doi.org/10.1073/pnas.90.9.4107
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  Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase.

  R Mandel, H J Ryser, F Ghani, M Wu, and D Peak

  PNAS May 1, 1993 90 (9) 4112-4116; https://doi.org/10.1073/pnas.90.9.4112
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  Coevolution of persistently infecting small DNA viruses and their hosts linked to host-interactive regulatory domains.

  F F Shadan and L P Villarreal

  PNAS May 1, 1993 90 (9) 4117-4121; https://doi.org/10.1073/pnas.90.9.4117
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  Loss of function of the Drosophila zfh-1 gene results in abnormal development of mesodermally derived tissues.

  Z C Lai, E Rushton, M Bate, and G M Rubin

  PNAS May 1, 1993 90 (9) 4122-4126; https://doi.org/10.1073/pnas.90.9.4122
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  Reconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathways.

  H Asao, T Takeshita, N Ishii, S Kumaki, M Nakamura, and K Sugamura

  PNAS May 1, 1993 90 (9) 4127-4131; https://doi.org/10.1073/pnas.90.9.4127
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  Photoreceptor twist: a solution to the false-color problem.

  R Wehner and G D Bernard

  PNAS May 1, 1993 90 (9) 4132-4135; https://doi.org/10.1073/pnas.90.9.4132
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  Crystal structure of a ubiquitin-dependent degradation substrate: a three-disulfide form of lysozyme.

  C P Hill, N L Johnston, and R E Cohen

  PNAS May 1, 1993 90 (9) 4136-4140; https://doi.org/10.1073/pnas.90.9.4136
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  Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries.

  R A Williamson, R Burioni, P P Sanna, L J Partridge, C F Barbas 3rd, and D R Burton

  PNAS May 1, 1993 90 (9) 4141-4145; https://doi.org/10.1073/pnas.90.9.4141
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  Altered processing of Alzheimer amyloid precursor protein in response to neuronal degeneration.

  K Iverfeldt, S I Walaas, and P Greengard

  PNAS May 1, 1993 90 (9) 4146-4150; https://doi.org/10.1073/pnas.90.9.4146
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  Recombination sequence-binding protein in thymocytes undergoing T-cell receptor gene rearrangement.

  K Muegge, M West, and S K Durum

  PNAS May 1, 1993 90 (9) 4151-4155; https://doi.org/10.1073/pnas.90.9.4151
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  Gene inoculation generates immune responses against human immunodeficiency virus type 1.

  B Wang, K E Ugen, V Srikantan, M G Agadjanyan, K Dang, Y Refaeli, A I Sato, J Boyer, W V Williams, and D B Weiner

  PNAS May 1, 1993 90 (9) 4156-4160; https://doi.org/10.1073/pnas.90.9.4156
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  Translation of mRNAs with degenerate initiation triplet AUU displays high initiation factor 2 dependence and is subject to initiation factor 3 repression.

  A La Teana, C L Pon, and C O Gualerzi

  PNAS May 1, 1993 90 (9) 4161-4165; https://doi.org/10.1073/pnas.90.9.4161
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  Identification of a colon mucosa gene that is down-regulated in colon adenomas and adenocarcinomas.

  C W Schweinfest, K W Henderson, S Suster, N Kondoh, and T S Papas

  PNAS May 1, 1993 90 (9) 4166-4170; https://doi.org/10.1073/pnas.90.9.4166
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  Rates of spontaneous mutation among RNA viruses.

  J W Drake

  PNAS May 1, 1993 90 (9) 4171-4175; https://doi.org/10.1073/pnas.90.9.4171
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  Controlled release of polypeptides from polyanhydrides.

  E Ron, T Turek, E Mathiowitz, M Chasin, M Hageman, and R Langer

  PNAS May 1, 1993 90 (9) 4176-4180; https://doi.org/10.1073/pnas.90.9.4176
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  Interaction of translation factor SELB with the formate dehydrogenase H selenopolypeptide mRNA.

  C Baron, J Heider, and A Böck

  PNAS May 1, 1993 90 (9) 4181-4185; https://doi.org/10.1073/pnas.90.9.4181
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  Proposed atomic structure of a truncated human immunodeficiency virus glycoprotein gp120 derived by molecular modeling: target CD4 recognition and docking mechanism.

  J L Gabriel and W M Mitchell

  PNAS May 1, 1993 90 (9) 4186-4190; https://doi.org/10.1073/pnas.90.9.4186
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  Images of evolution: origin of spontaneous RNA replication waves.

  J S McCaskill and G J Bauer

  PNAS May 1, 1993 90 (9) 4191-4195; https://doi.org/10.1073/pnas.90.9.4191
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  Cloning and characterization of a fourth human somatostatin receptor.

  L Rohrer, F Raulf, C Bruns, R Buettner, F Hofstaedter, and R Schüle

  PNAS May 1, 1993 90 (9) 4196-4200; https://doi.org/10.1073/pnas.90.9.4196
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  Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction.

  N Kobayashi, T Kono, M Hatakeyama, Y Minami, T Miyazaki, R M Perlmutter, and T Taniguchi

  PNAS May 1, 1993 90 (9) 4201-4205; https://doi.org/10.1073/pnas.90.9.4201
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  Sequence-specific scission of DNA by the chemical nuclease activity of 1,10-phenanthroline-copper(I) targeted by RNA.

  C B Chen, M B Gorin, and D S Sigman

  PNAS May 1, 1993 90 (9) 4206-4210; https://doi.org/10.1073/pnas.90.9.4206
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  Functional replacement of the hemolysin A transport signal by a different primary sequence.

  F Zhang, D I Greig, and V Ling

  PNAS May 1, 1993 90 (9) 4211-4215; https://doi.org/10.1073/pnas.90.9.4211
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  Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

  A Ziegler, D J Leffell, S Kunala, H W Sharma, M Gailani, J A Simon, A J Halperin, H P Baden, P E Shapiro, and A E Bale

  PNAS May 1, 1993 90 (9) 4216-4220; https://doi.org/10.1073/pnas.90.9.4216
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  Description of the leukocyte function-associated antigen 1 (LFA-1 or CD11a) promoter.

  R D Cornwell, K A Gollahon, and D D Hickstein

  PNAS May 1, 1993 90 (9) 4221-4225; https://doi.org/10.1073/pnas.90.9.4221
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  Mapping the determinants of human immunodeficiency virus 2 for infectivity, replication efficiency, and cytopathicity.

  R Talbott, G Kraus, D Looney, and F Wong-Staal

  PNAS May 1, 1993 90 (9) 4226-4230; https://doi.org/10.1073/pnas.90.9.4226
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  Characterization of a high-affinity galanin receptor in the rat anterior pituitary: absence of biological effect and reduced membrane binding of the antagonist M15 differentiate it from the brain/gut receptor.

  D Wynick, D M Smith, M Ghatei, K Akinsanya, R Bhogal, P Purkiss, P Byfield, N Yanaihara, and S R Bloom

  PNAS May 1, 1993 90 (9) 4231-4235; https://doi.org/10.1073/pnas.90.9.4231
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  A Drosophila G-protein alpha subunit, Gf alpha, expressed in a spatially and temporally restricted pattern during Drosophila development.

  F Quan, W J Wolfgang, and M Forte

  PNAS May 1, 1993 90 (9) 4236-4240; https://doi.org/10.1073/pnas.90.9.4236
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  DNA sequencing: modular primers assembled from a library of hexamers or pentamers.

  L E Kotler, D Zevin-Sonkin, I A Sobolev, A D Beskin, and L E Ulanovsky

  PNAS May 1, 1993 90 (9) 4241-4245; https://doi.org/10.1073/pnas.90.9.4241
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  Additivity of mutant effects assessed by binomial mutagenesis.

  L M Gregoret and R T Sauer

  PNAS May 1, 1993 90 (9) 4246-4250; https://doi.org/10.1073/pnas.90.9.4246
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  Stimulation by phospholipids of a protein-tyrosine-phosphatase containing two src homology 2 domains.

  Z Zhao, S H Shen, and E H Fischer

  PNAS May 1, 1993 90 (9) 4251-4255; https://doi.org/10.1073/pnas.90.9.4251
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  Low density lipoprotein- and high density lipoprotein-mediated signal transduction and exocytosis in alveolar type II cells.

  T A Voyno-Yasenetskaya, L G Dobbs, S K Erickson, and R L Hamilton

  PNAS May 1, 1993 90 (9) 4256-4260; https://doi.org/10.1073/pnas.90.9.4256
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  Expression of complete keratin filaments in mouse L cells augments cell migration and invasion.

  Y W Chu, R B Runyan, R G Oshima, and M J Hendrix

  PNAS May 1, 1993 90 (9) 4261-4265; https://doi.org/10.1073/pnas.90.9.4261
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  Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease.

  M Shahabuddin, T Toyoshima, M Aikawa, and D C Kaslow

  PNAS May 1, 1993 90 (9) 4266-4270; https://doi.org/10.1073/pnas.90.9.4266
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  Three-dimensional structure of a human immunoglobulin with a hinge deletion.

  L W Guddat, J N Herron, and A B Edmundson

  PNAS May 1, 1993 90 (9) 4271-4275; https://doi.org/10.1073/pnas.90.9.4271
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  Differential regulation of inducible nitric oxide synthase by fibroblast growth factors and transforming growth factor beta in bovine retinal pigmented epithelial cells: inverse correlation with cellular proliferation.

  O Goureau, M Lepoivre, F Becquet, and Y Courtois

  PNAS May 1, 1993 90 (9) 4276-4280; https://doi.org/10.1073/pnas.90.9.4276
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  Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors.

  D M Heery, T Zacharewski, B Pierrat, H Gronemeyer, P Chambon, and R Losson

  PNAS May 1, 1993 90 (9) 4281-4285; https://doi.org/10.1073/pnas.90.9.4281
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  Associative learning potentiates protein kinase C activation in synaptosomes of the rabbit hippocampus.

  K Sunayashiki-Kusuzaki, D S Lester, B G Schreurs, and D L Alkon

  PNAS May 1, 1993 90 (9) 4286-4289; https://doi.org/10.1073/pnas.90.9.4286
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  Dexamethasone negatively regulates the activity of a chimeric dihydrofolate reductase/glucocorticoid receptor protein.

  D I Israel and R J Kaufman

  PNAS May 1, 1993 90 (9) 4290-4294; https://doi.org/10.1073/pnas.90.9.4290
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  PutA protein, a membrane-associated flavin dehydrogenase, acts as a redox-dependent transcriptional regulator.

  P Ostrovsky de Spicer and S Maloy

  PNAS May 1, 1993 90 (9) 4295-4298; https://doi.org/10.1073/pnas.90.9.4295
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  Two Neurospora mitochondrial plasmids encode DNA polymerases containing motifs characteristic of family B DNA polymerases but lack the sequence Asp-Thr-Asp.

  Q Li and F E Nargang

  PNAS May 1, 1993 90 (9) 4299-4303; https://doi.org/10.1073/pnas.90.9.4299
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  General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.

  G L Wang and G L Semenza

  PNAS May 1, 1993 90 (9) 4304-4308; https://doi.org/10.1073/pnas.90.9.4304
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  Localization of the mRNA for a chicken prion protein by in situ hybridization.

  D A Harris, P Lele, and W D Snider

  PNAS May 1, 1993 90 (9) 4309-4313; https://doi.org/10.1073/pnas.90.9.4309
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  Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3.

  R N Pearse, R Feinman, K Shuai, J E Darnell Jr, and J V Ravetch

  PNAS May 1, 1993 90 (9) 4314-4318; https://doi.org/10.1073/pnas.90.9.4314
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  The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments.

  C Pannetier, M Cochet, S Darche, A Casrouge, M Zöller, and P Kourilsky

  PNAS May 1, 1993 90 (9) 4319-4323; https://doi.org/10.1073/pnas.90.9.4319
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  Analysis of pyruvate kinase-deficiency mutations that produce nonspherocytic hemolytic anemia.

  L Baronciani and E Beutler

  PNAS May 1, 1993 90 (9) 4324-4327; https://doi.org/10.1073/pnas.90.9.4324