New Research In
Physical Sciences
Social Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
- Agricultural Sciences
- Anthropology
- Applied Biological Sciences
- Biochemistry
- Biophysics and Computational Biology
- Cell Biology
- Developmental Biology
- Ecology
- Environmental Sciences
- Evolution
- Genetics
- Immunology and Inflammation
- Medical Sciences
- Microbiology
- Neuroscience
- Pharmacology
- Physiology
- Plant Biology
- Population Biology
- Psychological and Cognitive Sciences
- Sustainability Science
- Systems Biology
Osmotin overexpression in potato delays development of disease symptoms.

Abstract
Transgenic potato and tobacco plants carrying the osmotin gene under the control of the cauliflower mosaic virus 35S promoter constitutively overexpressed osmotin to a level of approximately 2% of total cellular protein. Leaves of transgenic potato plants exhibited delayed development of disease symptoms after inoculation with spore suspensions of Phytophthora infestans, which is the cause of late blight disease of potato. In contrast, transgenic tobacco plants did not display any change in the development of disease symptoms when challenged with either spore suspensions or fungal mycelia of Phytophthora parasitica var. nicotianae. Using in vitro assays, purified osmotin was found to be more effective against P. infestans. Some inhibition of P. parasitica also was observed in vitro even though no in vivo effect could be established.