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Table of Contents
October 28, 1997; vol. 94 no. 22
Perspectives
- You have accessFluorescence correlation spectroscopy: Diagnostics for sparse moleculesSudipta Maiti, Ulrich Haupts, and Watt W. Webb
Physical Sciences
Chemistry
- You have accessOn roads not taken in the evolution of protein catalysts: Antibody steroid isomerases that use an enamine mechanismChao-Hsiung Lin, Timothy Z. Hoffman, Peter Wirsching, Carlos F. Barbas III, Kim D. Janda, and Richard A. Lerner
- You have accessMaking chemistry selectable by linking it to infectivityChangshou Gao, Chao-Hsiung Lin, Chih-Hung L. Lo, Shenlan Mao, Peter Wirsching, Richard A. Lerner, and Kim D. Janda
- You have accessElectrophilic nitration of alkanes with nitronium hexafluorophosphateGeorge A. Olah, Pichika Ramaiah, and G. K. Surya Prakash
Biological Sciences
Biochemistry
- You have accessProtein–protein interactions among the Aux/IAA proteinsJungmook Kim, Klaus Harter, and Athanasios Theologis
- You have accessCharacterization of recombinant phytochrome from the cyanobacterium SynechocystisTilman Lamparter, Franz Mittmann, Wolfgang Gärtner, Thomas Börner, Elmar Hartmann, and Jon Hughes
- You have accessPrp43: An RNA helicase-like factor involved in spliceosome disassemblyJaime E. Arenas and John N. Abelson
- You have accessCloning of mDEAH9, a putative RNA helicase and mammalian homologue of Saccharomyces cerevisiae splicing factor Prp43Sherry Gee, Sharon Wald Krauss, Estelle Miller, Kazuko Aoyagi, Jaime Arenas, and John G. Conboy
- You have accessStructural evidence for a second sialic acid binding site in avian influenza virus neuraminidasesJoseph N. Varghese, Peter M. Colman, Albertus van Donkelaar, Tony J. Blick, Anjali Sahasrabudhe, and Jennifer L. McKimm-Breschkin
- You have accessThe crystal structure of human interferon β at 2.2-Å resolutionMichael Karpusas, Matthias Nolte, Christopher B. Benton, Werner Meier, William N. Lipscomb, and Susan Goelz
- You have accessGlu-tRNAGln amidotransferase: A novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation
- Inaugural Article
Alan W. Curnow, Kwang-won Hong, Robert Yuan, Sung-il Kim, Orlando Martins, Wade Winkler, Tina M. Henkin, and Dieter Söll - You have accessCloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and DrosophilaJan A. van der Knaap, Jan Willem Borst, Peter C. van der Vliet, Reiner Gentz, and H. Th. Marc Timmers
- You have accessSynthesis and screening of small molecule libraries active in binding to DNAGerald W. Shipps Jr., Kent E. Pryor, Jun Xian, David A. Skyler, Eric H. Davidson, and Julius Rebek Jr.
- You have accessThe amino-terminal region of Tyk2 sustains the level of interferon α receptor 1, a component of the interferon α/β receptorM. Cristina Gauzzi, Giovanna Barbieri, Marc F. Richter, Gilles Uzé, Leona Ling, Marc Fellous, and Sandra Pellegrini
- You have accessStructure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bugPablo Fuentes-Prior, Christiane Noeske-Jungblut, Peter Donner, Wolf-Dieter Schleuning, Robert Huber, and Wolfram Bode
- You have accessCharacterization of a genetically engineered inactivation-resistant coagulation factor VIIIaSteven W. Pipe and Randal J. Kaufman
- You have accessRespiratory chain is required to maintain oxidized states of the DsbA-DsbB disulfide bond formation system in aerobically growing Escherichia coli cellsTaeko Kobayashi, Satoshi Kishigami, Michio Sone, Hachiro Inokuchi, Tatsushi Mogi, and Koreaki Ito
- You have accessRecA tests homology at both pairing and strand exchangeL. Rochelle Bazemore, Ewa Folta-Stogniew, Masayuki Takahashi, and Charles M. Radding
- You have accessExtensive purification of a putative RNA polymerase I holoenzyme from plants that accurately initiates rRNA gene transcription in vitroJulio Saez-Vasquez and Craig S. Pikaard
- You have accessGrowth and viability of macrophages continuously stimulated to produce nitric oxideJohn C. Zhuang and Gerald N. Wogan
- You have accessConformation of coenzyme pyrroloquinoline quinone and role of Ca2+ in the catalytic mechanism of quinoprotein methanol dehydrogenaseYa-Jun Zheng and Thomas C. Bruice
- You have accessMolding a peptide into an RNA site by in vivo peptide evolutionKazuo Harada, Shelley S. Martin, Ruoying Tan, and Alan D. Frankel
- You have accessParticipation of the nuclear cap binding complex in pre-mRNA 3′ processingSean M. Flaherty, Puri Fortes, Elisa Izaurralde, Iain W. Mattaj, and Gregory M. Gilmartin
- You have accessBoth N-terminal myosin-binding and C-terminal actin-binding sites on smooth muscle caldesmon are required for caldesmon-mediated inhibition of actin filament velocityZe Wang, He Jiang, Zhi-Qiong Yang, and Samuel Chacko
Biophysics
- You have accessMolecular switch in signal transduction: Reaction paths of the conformational changes in ras p21Jianpeng Ma and Martin Karplus
- You have accessA structural census of the current population of protein sequencesMark Gerstein and Michael Levitt
- You have accessPreferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: Role in restricted conformational mobility and compaction of native stateBrent S. Kendrick, Byeong S. Chang, Tsutomu Arakawa, Brian Peterson, Theodore W. Randolph, Mark C. Manning, and John F. Carpenter
- You have accessEffects of extracellular Ca2+ concentration on hair-bundle stiffness and gating-spring integrity in hair cellsRobert E. Marquis and A. J. Hudspeth
- You have accessAssigning folds to the proteins encoded by the genome of Mycoplasma genitaliumDaniel Fischer and David Eisenberg
- You have accessMechanical separation of the complementary strands of DNAB. Essevaz-Roulet, U. Bockelmann, and F. Heslot
Cell Biology
- You have accessHuman deoxycytidine kinase is located in the cell nucleusMagnus Johansson, Sophia Brismar, and Anna Karlsson
- You have accessControl of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowthWataru Araki and Richard J. Wurtman
- You have accessActivation of distinct caspase-like proteases by Fas and reaper in Drosophila cellsToru Kondo, Takakazu Yokokura, and Shigekazu Nagata
- You have accessProteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinases, c-Jun N-terminal kinases, and P38 kinaseChuanshu Huang, Wei-Ya Ma, Clarence A. Ryan, and Zigang Dong
- You have accessConversion of cysteine to formylglycine: A protein modification in the endoplasmic reticulumThomas Dierks, Bernhard Schmidt, and Kurt von Figura
- You have accessAbnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channelTakashi Miki, Fumi Tashiro, Toshihiko Iwanaga, Kazuaki Nagashima, Hideyuki Yoshitomi, Hiroyuki Aihara, Yoshio Nitta, Tohru Gonoi, Nobuya Inagaki, Jun-ichi Miyazaki, and Susumu Seino
Developmental Biology
- You have accessMouse Eya genes are expressed during limb tendon development and encode a transcriptional activation functionPin-Xian Xu, Jane Cheng, Jonathan A. Epstein, and Richard L. Maas
- You have accessXenopus Zic3, a primary regulator both in neural and neural crest developmentKatsunori Nakata, Takeharu Nagai, Jun Aruga, and Katsuhiko Mikoshiba
Evolution
- You have accessIdentification of active sites in amidase: Evolutionary relationship between amide bond- and peptide bond-cleaving enzymesMichihiko Kobayashi, Yoshie Fujiwara, Masahiko Goda, Hidenobu Komeda, and Sakayu Shimizu
- You have accessConvergent evolution of apolipoprotein(a) in primates and hedgehogRichard M. Lawn, Karen Schwartz, and Laszlo Patthy
- You have accessPhalangeal curvature and positional behavior in extinct sloth lemurs (Primates, Palaeopropithecidae)William L. Jungers, Laurie R. Godfrey, Elwyn L. Simons, and Prithijit S. Chatrath
- You have accessEvolution of gilled mushrooms and puffballs inferred from ribosomal DNA sequencesDavid S. Hibbett, Elizabeth M. Pine, Ewald Langer, Gitta Langer, and Michael J. Donoghue
- You have accessOrigin and evolution of the slime molds (Mycetozoa)Sandra L. Baldauf and W. Ford Doolittle
Genetics
- You have accessEndosperm balance number manipulation for direct in vivo germplasm introgression to potato from a sexually isolated relative (Solanum commersonii Dun.)Domenico Carputo, Amalia Barone, Teodoro Cardi, Angela Sebastiano, Luigi Frusciante, and Stanley J. Peloquin
- You have accessHighly conservative reciprocal translocations formed by apparent joining of exchanged DNA double-strand break endsPeng Wang, Rui-Hua Zhou, Ying Zou, Colleen K. Jackson-Cook, and Lawrence F. Povirk
- You have accessDHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesisGinger E. Carney, Andrew A. Wade, Rajat Sapra, Elliott S. Goldstein, and Michael Bender
- You have accessA gene spans the pseudoautosomal boundary in miceSteve Palmer, Jo Perry, David Kipling, and Alan Ashworth
- You have accessIncomplete penetrance of familial retinoblastoma linked to germ-line mutations that result in partial loss of RB functionGregory A. Otterson, Wei-dong Chen, Amy B. Coxon, Samir N. Khleif, and Frederic J. Kaye
Immunology
- You have accessEpstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietinOdile Devergne, Mark Birkenbach, and Elliott Kieff
- You have accessInteraction of pigeon cytochrome c-(43–58) peptide analogs with either T cell antigen receptor or I-Ab moleculeYasushi Itoh, Kiichi Kajino, Kazumasa Ogasawara, Akio Takahashi, Ken-ichi Namba, Izumi Negishi, Naoto Matsuki, Kazuya Iwabuchi, Mitsuaki Kakinuma, Robert A. Good, and Kazunori Onoé
- You have accessSevere reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2William A. Kuziel, Sharon J. Morgan, Tracey C. Dawson, Stephanie Griffin, Oliver Smithies, Klaus Ley, and Nobuyo Maeda
- You have accessTargeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion proteinTheresa J. Goletz, Kurt R. Klimpel, Naveen Arora, Stephen H. Leppla, Jerry M. Keith, and Jay A. Berzofsky
- You have accessPrevention of development of autoimmune disease in BXSB mice by mixed bone marrow transplantationBing-Yan Wang, Cherry, Nagwa S. El-Badri, and Robert A. Good
Medical Sciences
- You have accessPosttranslational regulation of cyclin D1 by retinoic acid: A chemoprevention mechanismJohn Langenfeld, Hiroaki Kiyokawa, David Sekula, Jay Boyle, and Ethan Dmitrovsky
- You have accessCell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domainsYing Jin, Xie L. Xu, Meng-Chun W. Yang, Fanglin Wei, Teck-Choon Ayi, Anne M. Bowcock, and Richard Baer
- You have accessIntracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189
- Inaugural Article
Shi-Yuan Cheng, Motoo Nagane, H.-J. Su Huang, and Webster K. Cavenee - You have accessCystic fibrosis transmembrane conductance regulator is an epithelial cell receptor for clearance of Pseudomonas aeruginosa from the lungGerald B. Pier, Martha Grout, and Tanweer S. Zaidi
- You have accessSelective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteinsAndrew V. Samuelson and Scott W. Lowe
- You have accessRestoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transferShahab A. Akhter, Christine A. Skaer, Alan P. Kypson, Patricia H. McDonald, Karsten C. Peppel, Donald D. Glower, Robert J. Lefkowitz, and Walter J. Koch
- You have accessEvaluating treatment protocols to prevent antibiotic resistanceSebastian Bonhoeffer, Marc Lipsitch, and Bruce R. Levin
- You have accessMechanical stretch induces vascular permeability factor in human mesangial cells: Mechanisms of signal transductionGabriella Gruden, Stephen Thomas, Davina Burt, Stephen Lane, Gary Chusney, Steven Sacks, and GianCarlo Viberti
- You have accessGene-based approach to human gene-phenotype correlations
- Inaugural Article
Thaddeus P. Dryja - You have accessAlternative genetic pathways in colorectal carcinogenesisSylviane Olschwang, Richard Hamelin, Pierre Laurent-Puig, Bénédicte Thuille, Yann De Rycke, You-Jun Li, Françoise Muzeau, Jacques Girodet, Rémy-Jacques Salmon, and Gilles Thomas
- You have accessGilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: A dose-dependent genetic interaction crucial to neonatal hyperbilirubinemiaMichael Kaplan, Paul Renbaum, Ephrat Levy-Lahad, Cathy Hammerman, Amnon Lahad, and Ernest Beutler
- You have accessProlonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous diseaseHarry L. Malech, Phillip B. Maples, Narda Whiting-Theobald, Gilda F. Linton, Sudhir Sekhsaria, Sarah J. Vowells, Fei Li, Judi A. Miller, Ellen DeCarlo, Steven M. Holland, Susan F. Leitman, Charles S. Carter, Robert E. Butz, Elizabeth J. Read, Thomas A. Fleisher, Richard D. Schneiderman, Dennis E. Van Epps, S. Kaye Spratt, Christopher A. Maack, Joseph A. Rokovich, Lawrence K. Cohen, and John I. Gallin
Microbiology
- You have accessCloning and characterization of the Flavobacterium johnsoniae (Cytophaga johnsonae) gliding motility gene, gldASarika Agarwal, David W. Hunnicutt, and Mark J. McBride
- You have accessProbing the assembly of transcription initiation complexes through changes in σN protease sensitivityPaul Casaz and Martin Buck
Neurobiology
- You have accessOperative GABAergic inhibition in hippocampal CA1 pyramidal neurons in experimental epilepsyM. Esclapez, J. C. Hirsch, R. Khazipov, Y. Ben-Ari, and C. Bernard
- You have accessLoss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient miceMonique R. Adams, Eugene P. Brandon, Elena H. Chartoff, Rejean L. Idzerda, Daniel M. Dorsa, and G. Stanley McKnight
- You have accessThe Caenorhabditis elegans seven-transmembrane protein ODR-10 functions as an odorant receptor in mammalian cellsYinong Zhang, Joseph H. Chou, Jonathan Bradley, Cornelia I. Bargmann, and Kai Zinn
- You have accessSynapsin I interacts with c-Src and stimulates its tyrosine kinase activityFranco Onofri, Silvia Giovedì, Paola Vaccaro, Andrew J. Czernik, Flavia Valtorta, Pietro De Camilli, Paul Greengard, and Fabio Benfenati
- You have accessResponse-reinforcement learning is dependent on N-methyl-d-aspartate receptor activation in the nucleus accumbens coreAnn E. Kelley, Stephanie L. Smith-Roe, and Matthew R. Holahan
- You have accessThe interaction between cytoplasmic dynein and dynactin is required for fast axonal transportClare M. Waterman-Storer, Sher B. Karki, Sergei A. Kuznetsov, Joel S. Tabb, Dieter G. Weiss, George M. Langford, and Erika L. F. Holzbaur
- You have accessDisruption of syntaxin-mediated protein interactions blocks neurotransmitter secretionV. O’Connor, C. Heuss, W. M. De Bello, T. Dresbach, M. P. Charlton, J. H. Hunt, L. L. Pellegrini, A. Hodel, M. M. Burger, H. Betz, G. J. Augustine, and T. Schäfer
- You have accessProtein kinase C as a signal for exocytosisJulia Billiard, Duk-Su Koh, Donner F. Babcock, and Bertil Hille
- You have accessRecurrent excitatory postsynaptic potentials induced by synchronized fast cortical oscillationsMiles A. Whittington, Roger D. Traub, Howard J. Faulkner, Ian M. Stanford, and John G. R. Jefferys
- You have accessHOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signalingXiajun Li and Iva Greenwald
- You have accessDefective γ-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice
- Inaugural Article
Paul A. Slesinger, Markus Stoffel, Yuh Nung Jan, and Lily Y. Jan
Pharmacology
- You have accessDesign of compounds that increase the absorption of polar moleculesCaryn Lang Bowe, Leila Mokhtarzadeh, Pushpa Venkatesan, Suresh Babu, Helena R. Axelrod, Michael J. Sofia, Ramesh Kakarla, Tin Yau Chan, Jae Seung Kim, Hye J. Lee, Gordon L. Amidon, Sally Y. Choe, Suzanne Walker, and Daniel Kahne
Physiology
- You have accessMuscarinic stimulation of synaptic activity by protein kinase C is inhibited by adenosine in cultured hippocampal neuronsAlexandre Bouron and Harald Reuter
Plant Biology
- You have accessTwo hemoglobin genes in Arabidopsis thaliana: The evolutionary origins of leghemoglobinsBen Trevaskis, Richard. A. Watts, Carol R. Andersson, Danny J. Llewellyn, Mark S. Hargrove, John S. Olson, Elizabeth S. Dennis, and W. James Peacock
- You have accessGenetic control of abscisic acid biosynthesis in maizeBao Cai Tan, Steven H. Schwartz, Jan A. D. Zeevaart, and Donald R. McCarty
Commentaries