Skip to main content
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian
  • Log in
  • My Cart

Main menu

  • Home
  • Articles
    • Current
    • Latest Articles
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • Archive
  • Front Matter
  • News
    • For the Press
    • Highlights from Latest Articles
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Purpose and Scope
    • Editorial and Journal Policies
    • Submission Procedures
    • For Reviewers
    • Author FAQ
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Home
Home

Advanced Search

  • Home
  • Articles
    • Current
    • Latest Articles
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • Archive
  • Front Matter
  • News
    • For the Press
    • Highlights from Latest Articles
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Purpose and Scope
    • Editorial and Journal Policies
    • Submission Procedures
    • For Reviewers
    • Author FAQ

New Research In

Physical Sciences

Featured Portals

  • Physics
  • Chemistry
  • Sustainability Science

Articles by Topic

  • Applied Mathematics
  • Applied Physical Sciences
  • Astronomy
  • Computer Sciences
  • Earth, Atmospheric, and Planetary Sciences
  • Engineering
  • Environmental Sciences
  • Mathematics
  • Statistics

Social Sciences

Featured Portals

  • Anthropology
  • Sustainability Science

Articles by Topic

  • Economic Sciences
  • Environmental Sciences
  • Political Sciences
  • Psychological and Cognitive Sciences
  • Social Sciences

Biological Sciences

Featured Portals

  • Sustainability Science

Articles by Topic

  • Agricultural Sciences
  • Anthropology
  • Applied Biological Sciences
  • Biochemistry
  • Biophysics and Computational Biology
  • Cell Biology
  • Developmental Biology
  • Ecology
  • Environmental Sciences
  • Evolution
  • Genetics
  • Immunology and Inflammation
  • Medical Sciences
  • Microbiology
  • Neuroscience
  • Pharmacology
  • Physiology
  • Plant Biology
  • Population Biology
  • Psychological and Cognitive Sciences
  • Sustainability Science
  • Systems Biology
Research Article

Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis

Yi-Te Hsu, Keith G. Wolter, and Richard J. Youle
PNAS April 15, 1997 94 (8) 3668-3672; https://doi.org/10.1073/pnas.94.8.3668
Yi-Te Hsu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Keith G. Wolter
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Richard J. Youle
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & SI
  • Info & Metrics
  • PDF
Loading

Online Impact

 

Article Information

vol. 94 no. 8 3668-3672
DOI: 
https://doi.org/10.1073/pnas.94.8.3668
PubMed: 
9108035

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Received November 8, 1996
  • Accepted January 29, 1997
  • Published April 15, 1997.

Copyright & Usage: 
© 1997

Author Information

  1. Yi-Te Hsu,
  2. Keith G. Wolter, and
  3. Richard J. Youle
  1. Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, Room 5D-37, Bethesda, MD, 20892

Footnotes

    • R. John Collier, Harvard Medical School, Boston, MA

    Cited By...

    • 969 Citations
    • 709 Citations
    • Google Scholar

    This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

    • The BCL-2 protein family: opposing activities that mediate cell death
      Richard J. Youle, Andreas Strasser
      Nature Reviews Molecular Cell Biology 2008 9 1
    • Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
      William C. Earnshaw, Luis M. Martins, Scott H. Kaufmann
      Annual Review of Biochemistry 1999 68 1
    • Mitochondria as the central control point of apoptosis
      Solange Desagher, Jean-Claude Martinou
      Trends in Cell Biology 2000 10 9
    • Mitochondria and cell death: outer membrane permeabilization and beyond
      Stephen W. G. Tait, Douglas R. Green
      Nature Reviews Molecular Cell Biology 2010 11 9
    • Movement of Bax from the Cytosol to Mitochondria during Apoptosis
      Keith G. Wolter, Yi-Te Hsu, Carolyn L. Smith, Amotz Nechushtan, Xu-Guang Xi, Richard J. Youle
      The Journal of Cell Biology 1997 139 5
    • The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis
      Stephan Frank, Brigitte Gaume, Elke S. Bergmann-Leitner, Wolfgang W. Leitner, Everett G. Robert, Frédéric Catez, Carolyn L. Smith, Richard J. Youle
      Developmental Cell 2001 1 4
    • Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis
      Solange Desagher, Astrid Osen-Sand, Anthony Nichols, Robert Eskes, Sylvie Montessuit, Sandra Lauper, Kinsey Maundrell, Bruno Antonsson, Jean-Claude Martinou
      The Journal of Cell Biology 1999 144 5
    • Mitochondria and Neuronal Survival
      David G. Nicholls, Samantha L. Budd
      Physiological Reviews 2000 80 1
    • The Role of Mitochondria in Apoptosis
      Chunxin Wang, Richard J. Youle
      Annual Review of Genetics 2009 43 1
    • Structure of Bax
      Motoshi Suzuki, Richard J. Youle, Nico Tjandra
      Cell 2000 103 4
    • Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
      M. Narita, S. Shimizu, T. Ito, T. Chittenden, R. J. Lutz, H. Matsuda, Y. Tsujimoto
      Proceedings of the National Academy of Sciences 1998 95 25
    • Breaking the mitochondrial barrier
      Jean-Claude Martinou, Douglas R. Green
      Nature Reviews Molecular Cell Biology 2001 2 1
    • Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
      S J Korsmeyer, M C Wei, M Saito, S Weiler, K J Oh, P H Schlesinger
      Cell Death & Differentiation 2000 7 12
    • Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
      Marina Konopleva, Rooha Contractor, Twee Tsao, Ismael Samudio, Peter P. Ruvolo, Shinichi Kitada, Xingming Deng, Dayong Zhai, Yue-Xi Shi, Thomas Sneed, Monique Verhaegen, Maria Soengas, Vivian R. Ruvolo, Teresa McQueen, Wendy D. Schober, Julie C. Watt, Tilahun Jiffar, Xiaoyang Ling, Frank C. Marini, David Harris, Martin Dietrich, Zeev Estrov, James McCubrey, W. Stratford May, John C. Reed, Michael Andreeff
      Cancer Cell 2006 10 5
    • Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
      Hyungjin Kim, Mubina Rafiuddin-Shah, Ho-Chou Tu, John R. Jeffers, Gerard P. Zambetti, James J.-D. Hsieh, Emily H.-Y. Cheng
      Nature Cell Biology 2006 8 12
    • Nanomaterials for Theranostics: Recent Advances and Future Challenges
      Eun-Kyung Lim, Taekhoon Kim, Soonmyung Paik, Seungjoo Haam, Yong-Min Huh, Kwangyeol Lee
      Chemical Reviews 2015 115 1
    • Death Signal-induced Localization of p53 Protein to Mitochondria
      Natalie D. Marchenko, Alexander Zaika, Ute M. Moll
      Journal of Biological Chemistry 2000 275 21
    • Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
      Mariusz Karbowski, Yang-Ja Lee, Brigitte Gaume, Seon-Yong Jeong, Stephan Frank, Amotz Nechushtan, Ansgar Santel, Margaret Fuller, Carolyn L. Smith, Richard J. Youle
      The Journal of Cell Biology 2002 159 6
    • Bax-induced Caspase Activation and Apoptosis via CytochromecRelease from Mitochondria Is Inhibitable by Bcl-xL
      Deborah M. Finucane, Ella Bossy-Wetzel, Nigel J. Waterhouse, Thomas G. Cotter, Douglas R. Green
      Journal of Biological Chemistry 1999 274 4
    • Bax Is Present as a High Molecular Weight Oligomer/Complex in the Mitochondrial Membrane of Apoptotic Cells
      Bruno Antonsson, Sylvie Montessuit, Belen Sanchez, Jean-Claude Martinou
      Journal of Biological Chemistry 2001 276 15
    • The Bcl-2 Protein Family
      Bruno Antonsson, Jean-Claude Martinou
      Experimental Cell Research 2000 256 1
    • Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?
      Matthew G. Vander Heiden, Craig B. Thompson
      Nature Cell Biology 1999 1 8
    • Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg2+Ions
      Robert Eskes, Bruno Antonsson, Astrid Osen-Sand, Sylvie Montessuit, Christoph Richter, Rémy Sadoul, Gonzalo Mazzei, Anthony Nichols, Jean-Claude Martinou
      The Journal of Cell Biology 1998 143 1
    • BAX activation is initiated at a novel interaction site
      Evripidis Gavathiotis, Motoshi Suzuki, Marguerite L. Davis, Kenneth Pitter, Gregory H. Bird, Samuel G. Katz, Ho-Chou Tu, Hyungjin Kim, Emily H.-Y. Cheng, Nico Tjandra, Loren D. Walensky
      Nature 2008 455 7216
    • Molecular targets in cerebral ischemia for developing novel therapeutics
      Suresh L. Mehta, Namratta Manhas, Ram Raghubir
      Brain Research Reviews 2007 54 1
    • Regulated Targeting of BAX to Mitochondria
      Ing Swie Goping, Atan Gross, Josée N. Lavoie, Mai Nguyen, Ronald Jemmerson, Kevin Roth, Stanley J. Korsmeyer, Gordon C. Shore
      The Journal of Cell Biology 1998 143 1
    • Bcl-2-family proteins: the role of the BH3 domain in apoptosis
      Ameeta Kelekar, Craig B Thompson
      Trends in Cell Biology 1998 8 8
    • Nonionic Detergents Induce Dimerization among Members of the Bcl-2 Family
      Yi-Te Hsu, Richard J. Youle
      Journal of Biological Chemistry 1997 272 21
    • Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
      Wei-Xing Zong, Chi Li, Georgia Hatzivassiliou, Tullia Lindsten, Qian-Chun Yu, Junying Yuan, Craig B. Thompson
      The Journal of Cell Biology 2003 162 1
    • JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins
      Fuminori Tsuruta, Jun Sunayama, Yasunori Mori, Seisuke Hattori, Shigeomi Shimizu, Yoshihide Tsujimoto, Katsuji Yoshioka, Norihisa Masuyama, Yukiko Gotoh
      The EMBO Journal 2004 23 8
    • Bax in Murine Thymus Is a Soluble Monomeric Protein That Displays Differential Detergent-induced Conformations
      Yi-Te Hsu, Richard J. Youle
      Journal of Biological Chemistry 1998 273 17
    • Bax Inhibitor-1, a Mammalian Apoptosis Suppressor Identified by Functional Screening in Yeast
      Qunli Xu, John C Reed
      Molecular Cell 1998 1 3
    • The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability
      M H Harris, C B Thompson
      Cell Death & Differentiation 2000 7 12
    • A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria
      Fabien Llambi, Tudor Moldoveanu, Stephen W.G. Tait, Lisa Bouchier-Hayes, Jamshid Temirov, Laura L. McCormick, Christopher P. Dillon, Douglas R. Green
      Molecular Cell 2011 44 4
    • Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
      Peter E. Czabotar, Dana Westphal, Grant Dewson, Stephen Ma, Colin Hockings, W. Douglas Fairlie, Erinna F. Lee, Shenggen Yao, Adeline Y. Robin, Brian J. Smith, David C.S. Huang, Ruth M. Kluck, Jerry M. Adams, Peter M. Colman
      Cell 2013 152 3
    • Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis
      Amotz Nechushtan, Carolyn L. Smith, Itschak Lamensdorf, Soo-Han Yoon, Richard J. Youle
      The Journal of Cell Biology 2001 153 6
    • JNK- and p38 Kinase-mediated Phosphorylation of Bax Leads to Its Activation and Mitochondrial Translocation and to Apoptosis of Human Hepatoma HepG2 Cells
      Bong-Jo Kim, Seung-Wook Ryu, Byoung-Joon Song
      Journal of Biological Chemistry 2006 281 30
    • BH3 Profiling Identifies Three Distinct Classes of Apoptotic Blocks to Predict Response to ABT-737 and Conventional Chemotherapeutic Agents
      Jing Deng, Nicole Carlson, Kunihiko Takeyama, Paola Dal Cin, Margaret Shipp, Anthony Letai
      Cancer Cell 2007 12 2
    • p38 Map Kinase Mediates Bax Translocation in Nitric Oxide–Induced Apoptosis in Neurons
      Saadi Ghatan, Stephen Larner, Yoshito Kinoshita, Michal Hetman, Leena Patel, Zhengui Xia, Richard J. Youle, Richard S. Morrison
      The Journal of Cell Biology 2000 150 2
    • Regulation of apoptosis by Bcl-2 family proteins
      Alexandrina Burlacu
      Journal of Cellular and Molecular Medicine 2003 7 3
    • Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol
      Frank Edlich, Soojay Banerjee, Motoshi Suzuki, Megan M. Cleland, Damien Arnoult, Chunxin Wang, Albert Neutzner, Nico Tjandra, Richard J. Youle
      Cell 2011 145 1
    • A Stapled BID BH3 Helix Directly Binds and Activates BAX
      Loren D. Walensky, Kenneth Pitter, Joel Morash, Kyoung Joon Oh, Scott Barbuto, Jill Fisher, Eric Smith, Gregory L. Verdine, Stanley J. Korsmeyer
      Molecular Cell 2006 24 2
    • Hsp70 Inhibits Heat-induced Apoptosis Upstream of Mitochondria by Preventing Bax Translocation
      Adam R. Stankiewicz, Guillaume Lachapelle, Cheryl P. Z. Foo, Stefanie M. Radicioni, Dick D. Mosser
      Journal of Biological Chemistry 2005 280 46
    • Nitric oxide and cell death
      Michael P Murphy
      Biochimica et Biophysica Acta (BBA) - Bioenergetics 1999 1411 2-3
    • Control of mitochondrial permeability by Bcl-2 family members
      Juanita C. Sharpe, Damien Arnoult, Richard J. Youle
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2004 1644 2-3
    • 14-3-3 Interacts Directly with and Negatively Regulates Pro-apoptotic Bax
      Masaya Nomura, Shigeomi Shimizu, Tomoyasu Sugiyama, Masashi Narita, Toshinori Ito, Hikaru Matsuda, Yoshihide Tsujimoto
      Journal of Biological Chemistry 2003 278 3
    • Prion Protein Protects Human Neurons against Bax-mediated Apoptosis
      Younes Bounhar, Yan Zhang, Cynthia G. Goodyer, Andréa LeBlanc
      Journal of Biological Chemistry 2001 276 42
    • Molecular biology of Bax and Bak activation and action
      Dana Westphal, Grant Dewson, Peter E. Czabotar, Ruth M. Kluck
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2011 1813 4
    • Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
      M. Vila, V. Jackson-Lewis, S. Vukosavic, R. Djaldetti, G. Liberatore, D. Offen, S. J. Korsmeyer, S. Przedborski
      Proceedings of the National Academy of Sciences 2001 98 5
    • Bcl-2 family proteins and mitochondria
      JohnC. Reed, JulianeM. Jurgensmeier, Shigemi Matsuyama
      Biochimica et Biophysica Acta (BBA) - Bioenergetics 1998 1366 1-2
    • PML induces a novel caspase-independent death process
      Frédérique Quignon, Frédéric De Bels, Marcel Koken, Jean Feunteun, Jean-Claude Ameisen, Hugues de Thé
      Nature Genetics 1998 20 3
    • Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival
      Kuniyasu Niizuma, Hidenori Endo, Pak H. Chan
      Journal of Neurochemistry 2009 109
    • The Phosphatidylinositol 3-Kinase (PI3K)-Akt Pathway Suppresses Bax Translocation to Mitochondria
      Fuminori Tsuruta, Norihisa Masuyama, Yukiko Gotoh
      Journal of Biological Chemistry 2002 277 16
    • p73 Induces Apoptosis via PUMA Transactivation and Bax Mitochondrial Translocation
      Gerry Melino, Francesca Bernassola, Marco Ranalli, Karen Yee, Wei Xing Zong, Marco Corazzari, Richard A. Knight, Doug R. Green, Craig Thompson, Karen H. Vousden
      Journal of Biological Chemistry 2004 279 9
    • Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies
      Alex R. D. Delbridge, Stephanie Grabow, Andreas Strasser, David L. Vaux
      Nature Reviews Cancer 2016 16 2
    • Caspases Induce CytochromecRelease from Mitochondria by Activating Cytosolic Factors
      Ella Bossy-Wetzel, Douglas R. Green
      Journal of Biological Chemistry 1999 274 25
    • Bcl-2 Prevents Bax Oligomerization in the Mitochondrial Outer Membrane
      Valery Mikhailov, Margarita Mikhailova, Donna J. Pulkrabek, Zheng Dong, Manjeri A. Venkatachalam, Pothana Saikumar
      Journal of Biological Chemistry 2001 276 21
    • Mitochondrial cell death effectors
      Dirk Brenner, Tak W Mak
      Current Opinion in Cell Biology 2009 21 6
    • Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
      K M Murphy, V Ranganathan, M L Farnsworth, M Kavallaris, R B Lock
      Cell Death & Differentiation 2000 7 1
    • Apoptosis: definition, mechanisms, and relevance to disease
      Pothana Saikumar, Zheng Dong, Valery Mikhailov, Michael Denton, Joel M Weinberg, Manjeri A Venkatachalam
      The American Journal of Medicine 1999 107 5
    • Bax and Bak Promote Apoptosis by Modulating Endoplasmic Reticular and Mitochondrial Ca2+Stores
      Leta K. Nutt, Abujiang Pataer, Jessica Pahler, Bingliang Fang, Jack Roth, David J. McConkey, Stephen G. Swisher
      Journal of Biological Chemistry 2002 277 11
    • Mitochondria in Neurodegeneration: Bioenergetic Function in Cell Life and Death
      Anne N. Murphy, Gary Fiskum, M. Flint Beal
      Journal of Cerebral Blood Flow & Metabolism 1999 19 3
    • BI-1 Regulates an Apoptosis Pathway Linked to Endoplasmic Reticulum Stress
      Han-Jung Chae, Hyung-Ryong Kim, Chunyan Xu, Beatrice Bailly-Maitre, Maryla Krajewska, Stan Krajewski, Steven Banares, Janice Cui, Murat Digicaylioglu, Ning Ke, Shinichi Kitada, Edward Monosov, Michael Thomas, Christina L Kress, Jeremy R Babendure, Roger Y Tsien, Stuart A Lipton, John C Reed
      Molecular Cell 2004 15 3
    • How the Bcl-2 family of proteins interact to regulate apoptosis
      Mark F van Delft, David CS Huang
      Cell Research 2006 16 2
    • Bax activation and mitochondrial insertion during apoptosis
      Lisenn Lalier, Pierre-François Cartron, Philippe Juin, Svetlana Nedelkina, Stephen Manon, Burkhart Bechinger, François M. Vallette
      Apoptosis 2007 12 5
    • Recent insights into the mechanism of glucocorticosteroid-induced apoptosis
      C W Distelhorst
      Cell Death & Differentiation 2002 9 1
    • Integrin-Mediated Survival Signals Regulate the Apoptotic Function of Bax through Its Conformation and Subcellular Localization
      Andrew P. Gilmore, Anthony D. Metcalfe, Lewis H. Romer, Charles H. Streuli
      The Journal of Cell Biology 2000 149 2
    • Mechanisms underlying hypoxia-induced neuronal apoptosis
      Kenneth J. Banasiak, Ying Xia, Gabriel G. Haddad
      Progress in Neurobiology 2000 62 3
    • When ER stress reaches a dead end
      Hery Urra, Estefanie Dufey, Fernanda Lisbona, Diego Rojas-Rivera, Claudio Hetz
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2013 1833 12
    • Glucocorticoids in T cell apoptosis and function
      M. J. Herold, K. G. McPherson, H. M. Reichardt
      Cellular and Molecular Life Sciences 2006 63 1
    • Apoptosis in neurodegenerative diseases: the role of mitochondria
      W.G Tatton, C.W Olanow
      Biochimica et Biophysica Acta (BBA) - Bioenergetics 1999 1410 2
    • How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
      Antonella Antignani, Richard J Youle
      Current Opinion in Cell Biology 2006 18 6
    • Bcl-2 family on guard at the ER
      Eva Szegezdi, David C. MacDonald, Tríona Ní Chonghaile, Sanjeev Gupta, Afshin Samali
      American Journal of Physiology-Cell Physiology 2009 296 5
    • ERK-1/2 and p38 Kinase Oppositely Regulate Nitric Oxide-induced Apoptosis of Chondrocytes in Association with p53, Caspase-3, and Differentiation Status
      Song-Ja Kim, Jung-Won Ju, Chun-Do Oh, Young-Mee Yoon, Woo Keun Song, Jae-Hong Kim, Yung Joon Yoo, Ok-Sun Bang, Shin-Sung Kang, Jang-Soo Chun
      Journal of Biological Chemistry 2002 277 2
    • N-terminal cleavage of Bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes Bcl-2-independent cytochrome C release and apoptotic cell death
      Gui Gao, Q. Ping Dou
      Journal of Cellular Biochemistry 2001 80 1
    • Hypoxia induces the expression of the pro-apoptotic gene BNIP3
      K Guo, G Searfoss, D Krolikowski, M Pagnoni, C Franks, K Clark, K T Yu, M Jaye, Y Ivashchenko
      Cell Death & Differentiation 2001 8 4
    • Mitochondria as the target of the pro-apoptotic protein Bax
      Emine Er, Lisa Oliver, Pierre-François Cartron, Philippe Juin, Stephen Manon, François M. Vallette
      Biochimica et Biophysica Acta (BBA) - Bioenergetics 2006 1757 9-10
    • Interaction with a Membrane Surface Triggers a Reversible Conformational Change in Bax Normally Associated with Induction of Apoptosis
      Jeremy A. Yethon, Raquel F. Epand, Brian Leber, Richard M. Epand, David W. Andrews
      Journal of Biological Chemistry 2003 278 49
    • Association of Bax and Bak Homo-oligomers in Mitochondria
      Valery Mikhailov, Margarita Mikhailova, Kurt Degenhardt, Manjeri A. Venkatachalam, Eileen White, Pothana Saikumar
      Journal of Biological Chemistry 2003 278 7
    • Reduced Macrophage Apoptosis Is Associated With Accelerated Atherosclerosis in Low-Density Lipoprotein Receptor-Null Mice
      June Liu, Douglas P. Thewke, Yan Ru Su, MacRae F. Linton, Sergio Fazio, Michael S. Sinensky
      Arteriosclerosis, Thrombosis, and Vascular Biology 2005 25 1
    • BCL2Family of Apoptosis-Related Genes: Functions and Clinical Implications in Cancer
      Hellinida Thomadaki, Andreas Scorilas
      Critical Reviews in Clinical Laboratory Sciences 2006 43 1
    • Bax-mediated Ca2+Mobilization Promotes CytochromecRelease during Apoptosis
      Leta K. Nutt, Joya Chandra, Abujiang Pataer, Bingliang Fang, Jack A. Roth, Stephen G. Swisher, Roger G. O'Neil, David J. McConkey
      Journal of Biological Chemistry 2002 277 23
    • The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update
      Waseem Ahmad Siddiqui, Amjid Ahad, Haseeb Ahsan
      Archives of Toxicology 2015 89 3
    • Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis
      D Westphal, R M Kluck, G Dewson
      Cell Death & Differentiation 2014 21 2
    • Control of mitochondrial integrity by Bcl-2 family members and caspase-independent cell death
      Maryanne Donovan, Thomas G. Cotter
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2004 1644 2-3
    • The X-Ray Structure of a BAK Homodimer Reveals an Inhibitory Zinc Binding Site
      Tudor Moldoveanu, Qian Liu, Ante Tocilj, Mark Watson, Gordon Shore, Kalle Gehring
      Molecular Cell 2006 24 5
    • Caspase-dependent Activation of Calpain during Drug-induced Apoptosis
      David E. Wood, Elizabeth W. Newcomb
      Journal of Biological Chemistry 1999 274 12
    • Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation
      Mariusz Karbowski, Richard J Youle
      Current Opinion in Cell Biology 2011 23 4
    • Nicotine Inactivation of the Proapoptotic Function of Bax through Phosphorylation
      Meiguo Xin, Xingming Deng
      Journal of Biological Chemistry 2005 280 11
    • Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands
      Catherine L. Day, Lin Chen, Sarah J. Richardson, Penny J. Harrison, David C. S. Huang, Mark G. Hinds
      Journal of Biological Chemistry 2005 280 6
    • The secrets of the Bcl-2 family
      A J García-Sáez
      Cell Death & Differentiation 2012 19 11
    • Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins
      Laurent M. Dejean, Sonia Martinez-Caballero, Stephen Manon, Kathleen W. Kinnally
      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2006 1762 2
    • Cellular and Molecular Pathways of Ischemic Neuronal Death
      Seok-Joon Won, Doo-Yeon Kim, Byoung-Joo Gwag
      BMB Reports 2002 35 1
    • Nuclear and mitochondrial apoptotic pathways of p53
      Ute M Moll, Alex Zaika
      FEBS Letters 2001 493 2-3
    • Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis
      Lena Große, Christian A Wurm, Christian Brüser, Daniel Neumann, Daniel C Jans, Stefan Jakobs
      The EMBO Journal 2016 35 4
    • Mitochondria—Judges and Executioners of Cell Death Sentences
      Patrick D. Bhola, Anthony Letai
      Molecular Cell 2016 61 5
    • Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential
      S S Smaili, Y-T Hsu, K M Sanders, J T Russell, R J Youle
      Cell Death & Differentiation 2001 8 9
    • Homeostatic control of lymphocyte survival: potential origins and implications
      David R. Plas, Jeffrey C. Rathmell, Craig B. Thompson
      Nature Immunology 2002 3 6
    • Role of Mitochondria and Caspases in Vitamin D-mediated Apoptosis of MCF-7 Breast Cancer Cells
      Carmen J. Narvaez, JoEllen Welsh
      Journal of Biological Chemistry 2001 276 12
    • HSP60, Bax, Apoptosis and the Heart
      S. Gupta, A. A. Knowlton
      Journal of Cellular and Molecular Medicine 2005 9 1
    • Apoptosis of Retinal Ganglion Cells in Glaucoma
      Robert W Nickells
      Survey of Ophthalmology 1999 43
    • p38 Kinase Regulates Nitric Oxide-induced Apoptosis of Articular Chondrocytes by Accumulating p53 via NFκB-dependent Transcription and Stabilization by Serine 15 Phosphorylation
      Song-Ja Kim, Sang-Gu Hwang, Deug Y. Shin, Shin-Sung Kang, Jang-Soo Chun
      Journal of Biological Chemistry 2002 277 36
    • Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax
      J. I. Fletcher, S. Meusburger, C. J. Hawkins, D. T. Riglar, E. F. Lee, W. D. Fairlie, D. C. S. Huang, J. M. Adams
      Proceedings of the National Academy of Sciences 2008 105 47
    • Phosphorylation of p38 Mitogen-Activated Protein Kinase Downstream of Bax-Caspase-3 Pathway Leads to Cell Death Induced by High d-Glucose in Human Endothelial Cells
      Hironori Nakagami, Ryuichi Morishita, Kei Yamamoto, Shin-ichi Yoshimura, Yoshiaki Taniyama, Motokuni Aoki, Hiroaki Matsubara, Shokei Kim, Yasufumi Kaneda, Toshio Ogihara
      Diabetes 2001 50 6
    • MOLECULAR MECHANISMS OF GLUCOCORTICOIDS IN THE CONTROL OF INFLAMMATION AND LYMPHOCYTE APOPTOSIS
      Jan P. Tuckermann, Anna Kleiman, Kirsty G. McPherson, Holger M. Reichardt
      Critical Reviews in Clinical Laboratory Sciences 2005 42 1
    • Bax Channel Inhibitors Prevent Mitochondrion-mediated Apoptosis and Protect Neurons in a Model of Global Brain Ischemia
      Claudio Hetz, Pierre-Alain Vitte, Agnes Bombrun, Tatiana K. Rostovtseva, Sylvie Montessuit, Agnes Hiver, Matthias K. Schwarz, Dennis J. Church, Stanley J. Korsmeyer, Jean-Claude Martinou, Bruno Antonsson
      Journal of Biological Chemistry 2005 280 52
    • Bcl-xL sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers
      Seon-Yong Jeong, Brigitte Gaume, Yang-Ja Lee, Yi-Te Hsu, Seung-Wook Ryu, Soo-Han Yoon, Richard J Youle
      The EMBO Journal 2004 23 10
    • Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria
      Y. Deng, X. Wu
      Proceedings of the National Academy of Sciences 2000 97 22
    • The protection of selenium on ROS mediated-apoptosis by mitochondria dysfunction in cadmium-induced LLC-PK1 cells
      Yi-jing Zhou, Shi-ping Zhang, Chang-wei Liu, Yun-qing Cai
      Toxicology in Vitro 2009 23 2
    • Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury
      Giampaolo Morciano, Carlotta Giorgi, Massimo Bonora, Silvia Punzetti, Rita Pavasini, Mariusz R. Wieckowski, Gianluca Campo, Paolo Pinton
      Journal of Molecular and Cellular Cardiology 2015 78
    • Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia
      Marina Konopleva, Twee Tsao, Peter Ruvolo, Irina Stiouf, Zeev Estrov, Clinton E. Leysath, Shourong Zhao, David Harris, Shirong Chang, C. Ellen Jackson, Mark Munsell, Nanjoo Suh, Gordon Gribble, Tadashi Honda, W. Stratford May, Michael B. Sporn, Michael Andreeff
      Blood 2002 99 1
    • Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells
      L M Mooney, K A Al-Sakkaf, B L Brown, P R M Dobson
      British Journal of Cancer 2002 87 8
    • BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore
      Loren D. Walensky, Evripidis Gavathiotis
      Trends in Biochemical Sciences 2011 36 12
    • Mitochondria and ceramide: intertwined roles in regulation of apoptosis
      Helene Birbes, Samer El Bawab, Lina M Obeid, Yusuf A Hannun
      Advances in Enzyme Regulation 2002 42
    • Molecular Cloning and Characterization of Bif-1
      Sandy M. Cuddeback, Hirohito Yamaguchi, Kiyoshi Komatsu, Toshiyuki Miyashita, Masao Yamada, Chun Wu, Sujay Singh, Hong-Gang Wang
      Journal of Biological Chemistry 2001 276 23
    • p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity
      Sonja Wolff, Susan Erster, Gustavo Palacios, Ute M Moll
      Cell Research 2008 18 7
    • A mitochondrial pool of sphingomyelin is involved in TNFα-induced Bax translocation to mitochondria
      Helene BIRBES, Chiara LUBERTO, Yi-Te HSU, Samer EL BAWAB, Yusuf A. HANNUN, Lina M. OBEID
      Biochemical Journal 2005 386 3
    • Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
      Andreas Hartmann, Patrick P. Michel, Jean-Denis Troadec, Annick Mouatt-Prigent, Baptiste A. Faucheux, Merle Ruberg, Yves Agid, Etienne C. Hirsch
      Journal of Neurochemistry 2001 76 6
    • p38 Mitogen-Activated Protein Kinase Mediates Cell Death and p21-Activated Kinase Mediates Cell Survival during Chemotherapeutic Drug-induced Mitotic Arrest
      Karl Deacon, Pratibha Mistry, Jonathan Chernoff, Jonathan L. Blank, Rajnikant Patel
      Molecular Biology of the Cell 2003 14 5
    • Apoptosis, the Role of Oxidative Stress and the Example of Solar UV Radiation
      Charareh Pourzand, Rex M. Tyrrell
      Photochemistry and Photobiology 1999 70 4
    • Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
      Teresa G. Tessner, Filipe Muhale, Terrence E. Riehl, Shrikant Anant, William F. Stenson
      Journal of Clinical Investigation 2004 114 11
    • Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
      Teresa G. Tessner, Filipe Muhale, Terrence E. Riehl, Shrikant Anant, William F. Stenson
      Journal of Clinical Investigation 2004 114 11
    • Apoptosis: checkpoint at the mitochondrial frontier
      Ella Bossy-Wetzel, Douglas R. Green
      Mutation Research/DNA Repair 1999 434 3
    • The role of p53 in neuronal cell death
      R S Morrison, Y Kinoshita
      Cell Death & Differentiation 2000 7 10
    • Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
      Nambin Yim, Seung-Wook Ryu, Kyungsun Choi, Kwang Ryeol Lee, Seunghee Lee, Hojun Choi, Jeongjin Kim, Mohammed R. Shaker, Woong Sun, Ji-Ho Park, Daesoo Kim, Won Do Heo, Chulhee Choi
      Nature Communications 2016 7 1
    • Mitochondria as a critical target of the chemotheraputic agent cisplatin in head and neck cancer
      Kevin J. Cullen, Zejia Yang, Lisa Schumaker, Zhongmin Guo
      Journal of Bioenergetics and Biomembranes 2007 39 1
    • Protein Phosphatase 2A Enhances the Proapoptotic Function of Bax through Dephosphorylation
      Meiguo Xin, Xingming Deng
      Journal of Biological Chemistry 2006 281 27
    • TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax
      G Bellot, P-F Cartron, E Er, L Oliver, P Juin, L C Armstrong, P Bornstein, K Mihara, S Manon, F M Vallette
      Cell Death & Differentiation 2007 14 4
    • Activation of Pro-death Bcl-2 Family Proteins and Mitochondria Apoptosis Pathway in Tumor Necrosis Factor-α-induced Liver Injury
      Yongge Zhao, Shuchen Li, Erin E. Childs, Diane K. Kuharsky, Xiao-Ming Yin
      Journal of Biological Chemistry 2001 276 29
    • Tumor Necrosis Factor Induces Phosphorylation and Translocation of BAD through a Phosphatidylinositide-3-OH Kinase-dependent Pathway
      John G. Pastorino, Marco Tafani, John L. Farber
      Journal of Biological Chemistry 1999 274 27
    • Pro-Apoptotic Apoptosis Protease–Activating Factor 1 (Apaf-1) Has a Cytoplasmic Localization Distinct from Bcl-2 or Bcl-XL
      George Hausmann, Lorraine A. O'Reilly, Rosemary van Driel, Jennifer G. Beaumont, Andreas Strasser, Jerry M. Adams, David C.S. Huang
      The Journal of Cell Biology 2000 149 3
    • Inhibition of Neuronal Apoptosis in Vitro and in Vivo Using TAT-Mediated Protein Transduction
      Gunnar P.H. Dietz, Ertugrul Kilic, Mathias Bähr
      Molecular and Cellular Neuroscience 2002 21 1
    • Nonapoptotic Function of BAD and BAX in Long-Term Depression of Synaptic Transmission
      Song Jiao, Zheng Li
      Neuron 2011 70 4
    • RhoA/Rho Kinase Up-regulate Bax to Activate a Mitochondrial Death Pathway and Induce Cardiomyocyte Apoptosis
      Dominic P. Del Re, Shigeki Miyamoto, Joan Heller Brown
      Journal of Biological Chemistry 2007 282 11
    • Bcl-2 family members: intracellular targeting, membrane-insertion, and changes in subcellular localization
      Anna Schinzel, Thomas Kaufmann, Christoph Borner
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2004 1644 2-3
    • Regulation of Intracellular pH Mediates Bax Activation in HeLa Cells Treated with Staurosporine or Tumor Necrosis Factor-α
      Marco Tafani, Joshua A. Cohn, Natalie O. Karpinich, Ronald J. Rothman, Matteo A. Russo, John L. Farber
      Journal of Biological Chemistry 2002 277 51
    • Role of apoptosis in hypoxic/ischemic damage in the kidney
      Pothana Saikumar, Manjeri A Venkatachalam
      Seminars in Nephrology 2003 23 6
    • A mathematical model of caspase function in apoptosis
      Martin Fussenegger, James E. Bailey, Jeffrey Varner
      Nature Biotechnology 2000 18 7
    • Insulin-Like Growth Factor-I and Over-Expression of Bcl-xL Prevent Glucose-Mediated Apoptosis in Schwann Cells
      Catherine L. Delaney, James W. Russell, Hsin-Lin Cheng, Eva L. Feldman
      Journal of Neuropathology & Experimental Neurology 2001 60 2
    • Membrane promotes tBID interaction with BCLXL
      Ana J García-Sáez, Jonas Ries, Mar Orzáez, Enrique Pérez-Payà, Petra Schwille
      Nature Structural & Molecular Biology 2009 16 11
    • Human Embryonic Stem Cells Have Constitutively Active Bax at the Golgi and Are Primed to Undergo Rapid Apoptosis
      Raluca Dumitru, Vivian Gama, B. Matthew Fagan, Jacquelyn J. Bower, Vijay Swahari, Larysa H. Pevny, Mohanish Deshmukh
      Molecular Cell 2012 46 5
    • Spatial and temporal changes in Bax subcellular localization during anoikis
      Anthony J. Valentijn, Anthony D. Metcalfe, Jane Kott, Charles H. Streuli, Andrew P. Gilmore
      The Journal of Cell Biology 2003 162 4
    • Tumor Necrosis Factor-related Apoptosis-inducing Ligand Activates a Lysosomal Pathway of Apoptosis That Is Regulated by Bcl-2 Proteins
      Nathan W. Werneburg, M. Eugenia Guicciardi, Steve F. Bronk, Scott H. Kaufmann, Gregory J. Gores
      Journal of Biological Chemistry 2007 282 39
    • Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function
      Jon Nilsen, Shuhua Chen, Ronald W Irwin, Sean Iwamoto, Roberta Diaz Brinton
      BMC Neuroscience 2006 7 1
    • Bcl-2 Inhibits a Fas-induced Conformational Change in the Bax N Terminus and Bax Mitochondrial Translocation
      Kathleen M. Murphy, Uldis N. Streips, Richard B. Lock
      Journal of Biological Chemistry 2000 275 23
    • Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane
      S Lucken-Ardjomande, S Montessuit, J-C Martinou
      Cell Death & Differentiation 2008 15 5
    • Inositol Hexakisphosphate Kinase-2, a Physiologic Mediator of Cell Death
      Eiichiro Nagata, Hongbo R. Luo, Adolfo Saiardi, Byoung-Il Bae, Norihiro Suzuki, Solomon H. Snyder
      Journal of Biological Chemistry 2005 280 2
    • Auto-activation of the Apoptosis Protein Bax Increases Mitochondrial Membrane Permeability and Is Inhibited by Bcl-2
      Chibing Tan, Paulina J. Dlugosz, Jun Peng, Zhi Zhang, Suzanne M. Lapolla, Scott M. Plafker, David W. Andrews, Jialing Lin
      Journal of Biological Chemistry 2006 281 21
    • Mitochondrial outer-membrane permeabilization and remodelling in apoptosis
      Alexis Jourdain, Jean-Claude Martinou
      The International Journal of Biochemistry & Cell Biology 2009 41 10
    • Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity
      Julie Wilson-Annan, Lorraine A. O'Reilly, Simon A. Crawford, George Hausmann, Jennifer G. Beaumont, Loes P. Parma, Lin Chen, Martin Lackmann, Trevor Lithgow, Mark G. Hinds, Catherine L. Day, Jerry M. Adams, David C.S. Huang
      The Journal of Cell Biology 2003 162 5
    • Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies
      Alexander G. Yakovlev, Alan I. Faden
      NeuroRX 2004 1 1
    • Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies
      Alexander G. Yakovlev, Alan I. Faden
      NeuroRX 2004 1 1
    • Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells
      Yu Zhang, Liang Zhou, Yong Li Bao, Yin Wu, Chun Lei Yu, Yan Xin Huang, Ying Sun, Li Hua Zheng, Yu Xin Li
      Chemico-Biological Interactions 2010 185 3
    • Novel Mechanism of Anti-apoptotic Function of 78-kDa Glucose-regulated Protein (GRP78)
      Hui Zhou, Yi Zhang, Yong Fu, Lauren Chan, Amy S. Lee
      Journal of Biological Chemistry 2011 286 29
    • Regulation of Apoptosis in Myeloid Cells by Interferon Consensus Sequence–Binding Protein
      Lucia Gabriele, Jan Phung, Jon Fukumoto, David Segal, I-Ming Wang, Paraskevi Giannakakou, Nathalie A. Giese, Keiko Ozato, Herbert C. Morse
      The Journal of Experimental Medicine 1999 190 3
    • 100 ns Molecular Dynamics Simulations to Study Intramolecular Conformational Changes in Bax
      Caroline Koshy, Marimuthu Parthiban, Ramanathan Sowdhamini
      Journal of Biomolecular Structure and Dynamics 2010 28 1
    • Bax: Addressed to kill
      Thibaud T. Renault, Stéphen Manon
      Biochimie 2011 93 9
    • BID-dependent and BID-independent pathways for BAX insertion into mitochondria
      S C Ruffolo, D G Breckenridge, M Nguyen, I S Goping, A Gross, S J Korsmeyer, H Li, J Yuan, G C Shore
      Cell Death & Differentiation 2000 7 11
    • Endoplasmic reticulum stress and apoptosis
      Jitka Faitova, Daniel Krekac, Roman Hrstka, Borivoj Vojtesek
      Cellular and Molecular Biology Letters 2006 11 4
    • Cisplatin-Induced Apoptosis of DRG Neurons Involves Bax Redistribution and Cytochrome cRelease But Not fas Receptor Signaling
      Elizabeth S. McDonald, Anthony J. Windebank
      Neurobiology of Disease 2002 9 2
    • Intestinal mucositis: the role of the Bcl-2 family, p53 and caspases in chemotherapy-induced damage
      Joanne M. Bowen, Rachel J. Gibson, Adrian G. Cummins, Dorothy M. K. Keefe
      Supportive Care in Cancer 2006 14 7
    • Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax
      Tim C. P. Somervaille, David C. Linch, Asim Khwaja
      Blood 2001 98 5
    • Mitochondrial outer membrane permeabilization during apoptosis: The role of mitochondrial fission
      Thomas Landes, Jean-Claude Martinou
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2011 1813 4
    • Apoptosis induced by cryo-injury in human colorectal cancer cells is associated with mitochondrial dysfunction
      Weng-Lang Yang, Tommaso Addona, Deepak G. Nair, Lixin Qi, T. S. Ravikumar
      International Journal of Cancer 2003 103 3
    • Caspase-Dependent Cytosolic Release of Cytochrome c and Membrane Translocation of Bax in p53-Induced Apoptosis
      Chong Feng Gao, Shuo Ren, Lilin Zhang, Takuma Nakajima, Shizuko Ichinose, Toshiko Hara, Katsuro Koike, Nobuo Tsuchida
      Experimental Cell Research 2001 265 1
    • Mitochondrial involvement in the point of no return in neuronal apoptosis
      L.K. Chang, G.V. Putcha, M. Deshmukh, E.M. Johnson
      Biochimie 2002 84 2-3
    • All along the watchtower: on the regulation of apoptosis regulators
      BENGT FADEEL, BORIS ZHIVOTOVSKY, STEN ORRENIUS
      The FASEB Journal 1999 13 13
    • Mitochondria, calcium and pro-apoptotic proteins as mediators in cell death signaling
      S.S. Smaili, Y.-T. Hsu, A.C.P. Carvalho, T.R. Rosenstock, J.C. Sharpe, R.J. Youle
      Brazilian Journal of Medical and Biological Research 2003 36 2
    • PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis
      Cunji Gao, Weiyong Sun, Melpo Christofidou-Solomidou, Motoshi Sawada, Debra K. Newman, Carmen Bergom, Steven M. Albelda, Shigemi Matsuyama, Peter J. Newman
      Blood 2003 102 1
    • Redistribution of Bax Is an Early Step in an Apoptotic Pathway Leading to Germ Cell Death in Rats, Triggered by Mild Testicular Hyperthermia1
      Cindy M. Yamamoto, Amiya P. Sinha Hikim, Phuong N. Huynh, Brian Shapiro, Yanhe Lue, Wael A. Salameh, Christina Wang, Ronald S. Swerdloff
      Biology of Reproduction 2000 63 6
    • Lysosomal membrane permeabilization during apoptosis - involvement of Bax?
      Katarina Kågedal, Ann-Charlotte Johansson, Uno Johansson, Gerd Heimlich, Karin Roberg, Nancy S. Wang, Juliane M. Jürgensmeier, Karin Öllinger
      International Journal of Experimental Pathology 2005 86 5
    • ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death
      Krishna Pada Sarker, Kamal Krishna Biswas, Munekazu Yamakuchi, Ki-Young Lee, Teruto Hahiguchi, Michael Kracht, Isao Kitajima, Ikuro Maruyama
      Journal of Neurochemistry 2003 85 1
    • Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia
      Beatriz Bellosillo, Neus Villamor, Armando López-Guillermo, Silvia Marcé, Francesc Bosch, Elias Campo, Emili Montserrat, Dolors Colomer
      Blood 2002 100 5
    • p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation
      M Schuler, U Maurer, J C Goldstein, F Breitenbücher, S Hoffarth, N J Waterhouse, D R Green
      Cell Death & Differentiation 2003 10 4
    • Central roles of apoptotic proteins in mitochondrial function
      S M Kilbride, J H M Prehn
      Oncogene 2013 32 22
    • MOMP, cell suicide as a BCL-2 family business
      Halime Kalkavan, Douglas R Green
      Cell Death & Differentiation 2018 25 1
    • The proapoptotic function of Drosophila Hid is conserved in mammalian cells
      W. N. Haining, C. Carboy-Newcomb, C. L. Wei, H. Steller
      Proceedings of the National Academy of Sciences 1999 96 9
    • Mediterranean diet and cardioprotection: The role of nitrite, polyunsaturated fatty acids, and polyphenols
      Sergiy M. Nadtochiy, Emily K. Redman
      Nutrition 2011 27 7-8
    • The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor ofAspergillus fumigatusvirulence in mice
      Julian Pardo, Christin Urban, Eva M. Galvez, Paul G. Ekert, Uwe Müller, June Kwon-Chung, Mario Lobigs, Arno Müllbacher, Reinhard Wallich, Christoph Borner, Markus M. Simon
      The Journal of Cell Biology 2006 174 4
    • Bcl-xL Blocks Transforming Growth Factor-β1-induced Apoptosis by Inhibiting CytochromecRelease and Not by Directly Antagonizing Apaf-1-dependent Caspase Activation in Prostate Epithelial Cells
      Jerry E. Chipuk, Manjunatha Bhat, Andrew Y. Hsing, Jianjie Ma, David Danielpour
      Journal of Biological Chemistry 2001 276 28
    • During Apoptosis Bcl-2 Changes Membrane Topology at Both the Endoplasmic Reticulum and Mitochondria
      Peter K Kim, Matthew G Annis, Paulina J Dlugosz, Brian Leber, David W Andrews
      Molecular Cell 2004 14 4
    • Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors
      Nathan R. Brady, Anne Hamacher-Brady, Roberta A. Gottlieb
      Biochimica et Biophysica Acta (BBA) - Bioenergetics 2006 1757 5-6
    • Regulation of Bax mitochondrial localization by Bcl-2 and Bcl-xL: Keep your friends close but your enemies closer
      Thibaud T. Renault, Oscar Teijido, Bruno Antonsson, Laurent M. Dejean, Stéphen Manon
      The International Journal of Biochemistry & Cell Biology 2013 45 1
    • The C-terminal helix of Bcl-xL mediates Bax retrotranslocation from the mitochondria
      F Todt, Z Cakir, F Reichenbach, R J Youle, F Edlich
      Cell Death & Differentiation 2013 20 2
    • Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway
      Seon-Hee Oh, Byung-Hoon Lee, Sung-Chul Lim
      Biochemical Pharmacology 2004 68 9
    • Ovarian Aging and Menopause: Current Theories, Hypotheses, and Research Models
      Julie M. Wu, Mary B. Zelinski, Donald K. Ingram, Mary Ann Ottinger
      Experimental Biology and Medicine 2005 230 11
    • Removal of Glutathione Produces Apoptosis and Necrosis in HepG2 Cells Overexpressing CYP2E1
      Defeng Wu, Arthur I. Cederbaum
      Alcoholism: Clinical and Experimental Research 2001 25 4
    • Removal of Glutathione Produces Apoptosis and Necrosis in HepG2 Cells Overexpressing CYP2E1
      Defeng Wu, Arthur I. Cederbaum
      Alcoholism: Clinical and Experimental Research 2001 25 4
    • SH3GLB, a New Endophilin-Related Protein Family Featuring an SH3 Domain
      Benoit Pierrat, Marjo Simonen, Maria Cueto, Jurgen Mestan, Paul Ferrigno, Jutta Heim
      Genomics 2001 71 2
    • Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins
      Haseeb Ahsan, Shannon Reagan-Shaw, Jorien Breur, Nihal Ahmad
      Cancer Letters 2007 249 2
    • Distinct Domains Control the Addressing and the Insertion of Bax into Mitochondria
      Pierre-François Cartron, Hubert Arokium, Lisa Oliver, Khaled Meflah, Stephen Manon, François M. Vallette
      Journal of Biological Chemistry 2005 280 11
    • Tauroursodeoxycholic Acid Partially Prevents Apoptosis Induced by 3-Nitropropionic Acid
      Cecilia M. P. Rodrigues, Cheryle Linehan- Stieers, C. Dirk Keene, Xiaoming Ma, Betsy T. Kren, Walter C. Low, Clifford J. Steer
      Journal of Neurochemistry 2008 75 6
    • A Bcl-xL–Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis
      Hongmei Li, Kambiz N. Alavian, Emma Lazrove, Nabil Mehta, Adrienne Jones, Ping Zhang, Pawel Licznerski, Morven Graham, Takuma Uo, Junhua Guo, Christoph Rahner, Ronald S. Duman, Richard S. Morrison, Elizabeth A. Jonas
      Nature Cell Biology 2013 15 7
    • Bax interacts with the voltage-dependent anion channel and mediates ethanol-induced apoptosis in rat hepatocytes
      Masayuki Adachi, Hajime Higuchi, Soichiro Miura, Toshifumi Azuma, Sayaka Inokuchi, Hidetsugu Saito, Shinzo Kato, Hiromasa Ishii
      American Journal of Physiology-Gastrointestinal and Liver Physiology 2004 287 3
    • GSK3β Promotes Apoptosis after Renal Ischemic Injury
      Zhiyong Wang, Andrea Havasi, Jonathan Gall, Ramon Bonegio, Zhijian Li, Haiping Mao, John H. Schwartz, Steven C. Borkan
      Journal of the American Society of Nephrology 2010 21 2
    • Glucocorticoid-Induced Apoptosis of Thymocytes: Requirement of Proteasome-Dependent Mitochondrial Activity
      Noriko Tonomura, Kelly McLaughlin, Lisa Grimm, Richard A. Goldsby, Barbara A. Osborne
      The Journal of Immunology 2003 170 5
    • TNF-α Signals Apoptosis through a Bid-Dependent Conformational Change in Bax that Is Inhibited by E1B 19K
      Denise Perez, Eileen White
      Molecular Cell 2000 6 1
    • Bax activation by Bim?
      P E Czabotar, P M Colman, D C S Huang
      Cell Death & Differentiation 2009 16 9
    • Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor
      Michael Lazarou, Diana Stojanovski, Ann E. Frazier, Aneta Kotevski, Grant Dewson, William J. Craigen, Ruth M. Kluck, David L. Vaux, Michael T. Ryan
      Journal of Biological Chemistry 2010 285 47
    • Minimal BH3 Peptides Promote Cell Death by Antagonizing Anti-apoptotic Proteins
      Carole Moreau, Pierre-François Cartron, Abigail Hunt, Khaled Meflah, Douglas R. Green, Gerard Evan, François M. Vallette, Philippe Juin
      Journal of Biological Chemistry 2003 278 21
    • Photoreceptor cell death and rescue in retinal detachment and degenerations
      Yusuke Murakami, Shoji Notomi, Toshio Hisatomi, Toru Nakazawa, Tatsuro Ishibashi, Joan W. Miller, Demetrios G. Vavvas
      Progress in Retinal and Eye Research 2013 37
    • Bax, Bak and beyond — mitochondrial performance in apoptosis
      Aida Peña‐Blanco, Ana J. García‐Sáez
      The FEBS Journal 2018 285 3
    • Bcl-XL Protects BimEL-induced Bax Conformational Change and Cytochrome c Release Independent of Interacting with Bax or BimEL
      Hirohito Yamaguchi, Hong-Gang Wang
      Journal of Biological Chemistry 2002 277 44
    • Protein translocation in apoptosis
      Alan G. Porter
      Trends in Cell Biology 1999 9 10
    • Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions
      Liang-yan Xue, Song-mao Chiu, Nancy L Oleinick
      Experimental Cell Research 2003 283 2
    • Use of High-Throughput Protein Array for Profiling of Differentially Expressed Proteins in Normal and Malignant Breast Tissue
      Gernot Hudelist, Margit Pacher-zavisin, Christian Singer, Tina Holper, Ernst Kubista, Martin Schreiber, Mahmood Manavi, Martin Bilban, Klaus Czerwenka
      Breast Cancer Research and Treatment 2004 86 3
    • Aspirin Induces Apoptosis through Release of Cytochrome c from Mitochondria
      Katja C. Zimmermann, Nigel J. Waterhouse, Joshua C. Goldstein, Martin Schuler, Douglas R. Green
      Neoplasia 2000 2 6
    • AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells
      Junfei Jin, Thomas D. Mullen, Qi Hou, Jacek Bielawski, Alicja Bielawska, Xiaoming Zhang, Lina M. Obeid, Yusuf A. Hannun, Yi-Te Hsu
      Journal of Lipid Research 2009 50 12
    • Apoptotic insults to human HepG2 cells induced by S -(+)-ketamine occurs through activation of a Bax-mitochondria-caspase protease pathway
      S.-T. Lee, T.-T. Wu, P.-Y. Yu, R.-M. Chen
      British Journal of Anaesthesia 2009 102 1
    • DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis
      Estelle Schmitt, Claudie Paquet, Myriam Beauchemin, Richard Bertrand
      Journal of Zhejiang University SCIENCE B 2007 8 6
    • Hepatitis C virus NS5A as a potential viral Bcl-2 homologue interacts with Bax and inhibits apoptosis in hepatocellular carcinoma
      Yih-Lin Chung, Meei-Ling Sheu, Sang-Hue Yen
      International Journal of Cancer 2003 107 1
    • Tissue expression and subcellular localization of the pro-survival molecule Bcl-w
      L A O'Reilly, C Print, G Hausmann, K Moriishi, S Cory, D C S Huang, A Strasser
      Cell Death & Differentiation 2001 8 5
    • Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines
      Wolfgang W Leitner, Leroy N Hwang, Elke S Bergmann-Leitner, Steven E Finkelstein, Stephan Frank, Nicholas P Restifo
      Vaccine 2004 22 11-12
    • Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line
      Aline A Fiebig, Weijia Zhu, Catherine Hollerbach, Brian Leber, David W Andrews
      BMC Cancer 2006 6 1
    • Glucagon-like Peptide-2 Receptor Activation Engages Bad and Glycogen Synthase Kinase-3 in a Protein Kinase A-dependent Manner and Prevents Apoptosis following Inhibition of Phosphatidylinositol 3-Kinase
      Bernardo Yusta, Jennifer Estall, Daniel J. Drucker
      Journal of Biological Chemistry 2002 277 28
    • MYCN silencing induces differentiation and apoptosis in human neuroblastoma cells
      Jung-Hee Kang, Piotr G. Rychahou, Titilope A. Ishola, Jingbo Qiao, B. Mark Evers, Dai H. Chung
      Biochemical and Biophysical Research Communications 2006 351 1
    • Protective function of taurine in glutamate-induced apoptosis in cultured neurons
      Rebecca Leon, Heng Wu, Ying Jin, Jianning Wei, Chandana Buddhala, Howard Prentice, Jang-Yen Wu
      Journal of Neuroscience Research 2009 87 5
    • Neuroprotective Effects of Leonurine on Ischemia/Reperfusion-Induced Mitochondrial Dysfunctions in Rat Cerebral Cortex
      Jia Qi, Zhen Yi Hong, Hong Xin, Yi Zhun Zhu
      Biological & Pharmaceutical Bulletin 2010 33 12
    • Pescadillo, a Novel Cell Cycle Regulatory Protein Abnormally Expressed in Malignant Cells
      Yoshito Kinoshita, Abel D. Jarell, Jean Michel Flaman, Greg Foltz, James Schuster, Bryce L. Sopher, Dwain K. Irvin, Kevin Kanning, Harley I. Kornblum, Peter S. Nelson, Phil Hieter, Richard S. Morrison
      Journal of Biological Chemistry 2001 276 9
    • Cell death and the mitochondria: therapeutic targeting of the BCL-2 family-driven pathway
      M J Roy, A Vom, P E Czabotar, G Lessene
      British Journal of Pharmacology 2014 171 8
    • Contribution of Bcl-2, but Not Bcl-xL and Bax, to Antiapoptotic Actions of Hepatocyte Growth Factor in Hypoxia-Conditioned Human Endothelial Cells
      Kei Yamamoto, Ryuichi Morishita, Shin-ichiro Hayashi, Hidetsugu Matsushita, Hidenori Nakagami, Atsushi Moriguchi, Kunio Matsumoto, Toshikazu Nakamura, Yasufumi Kaneda, Toshio Ogihara
      Hypertension 2001 37 5
    • Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils
      Grant Dewson, Gerald M. Cohen, Andrew J. Wardlaw
      Blood 2001 98 7
    • UVA/B-Induced Apoptosis in Human Melanocytes Involves Translocation of Cathepsins and Bcl-2 Family Members
      Cecilia A. Bivik, Petra K. Larsson, Katarina M. Kågedal, Inger K. Rosdahl, Karin M. Öllinger
      Journal of Investigative Dermatology 2006 126 5
    • Bcl-XL translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress
      Leila Cuttle, Xiao-Ju Zhang, Zoltan H. Endre, Clay Winterford, Glenda C. Gobé
      Kidney International 2001 59 5
    • Identification and Characterization of Nuclear Factor κB Binding Sites in the Murine bcl-χ Promoter
      J. N. Glasgow, T. Wood, J. R. Perez-Polo
      Journal of Neurochemistry 2002 75 4
    • Bid Is Upstream of Lysosome-Mediated Caspase 2 Activation in Tumor Necrosis Factor α–Induced Hepatocyte Apoptosis
      M. Eugenia Guicciardi, Steven F. Bronk, Nathan W. Werneburg, Xiao-Ming Yin, Gregory J. Gores
      Gastroenterology 2005 129 1
    • Expression of a non-functional p53 affects the sensitivity of cancer cells to gemcitabine
      Carlos Mar�a Galmarini, Marilyn L. Clarke, Nicole Falette, Alain Puisieux, John R. Mackey, Charles Dumontet
      International Journal of Cancer 2002 97 4
    • Neutrophil stress and apoptosis underlie myeloid dysfunction in glycogen storage disease type Ib
      So Youn Kim, Hyun Sik Jun, Paul A. Mead, Brian C. Mansfield, Janice Y. Chou
      Blood 2008 111 12
    • Resveratrol Protects against Oxidized LDL-Induced Breakage of the Blood-Brain Barrier by Lessening Disruption of Tight Junctions and Apoptotic Insults to Mouse Cerebrovascular Endothelial Cells
      Yi-Ling Lin, Huai-Chia Chang, Ta-Liang Chen, Jin-Han Chang, Wen-Ta Chiu, Jia-Wei Lin, Ruei-Ming Chen
      The Journal of Nutrition 2010 140 12
    • Involvement of the N-terminus of Bax in its intracellular localization and function
      P.-F. Cartron, C. Moreau, L. Oliver, E. Mayat, K. Meflah, F.M. Vallette
      FEBS Letters 2002 512 1-3
    • Small-molecule Bax agonists for cancer therapy
      Meiguo Xin, Rui Li, Maohua Xie, Dongkyoo Park, Taofeek K. Owonikoko, Gabriel L. Sica, Patrick E. Corsino, Jia Zhou, Chunyong Ding, Mark A. White, Andrew T. Magis, Suresh S. Ramalingam, Walter J. Curran, Fadlo R. Khuri, Xingming Deng
      Nature Communications 2014 5 1
    • Temperature-dependent Arrest of Neutrophil Apoptosis
      James G. Pryde, Annemieke Walker, Adriano G. Rossi, Sharon Hannah, Christopher Haslett
      Journal of Biological Chemistry 2000 275 43
    • Atypical antipsychotics attenuate neurotoxicity of ?-amyloid(25-35) by modulating Bax and Bcl-Xl/s expression and localization
      Zelan Wei, Darrell D. Mousseau, J. Steven Richardson, Lillian E. Dyck, Xin-Min Li
      Journal of Neuroscience Research 2003 74 6
    • Oestrogen prevents cardiomyocyte apoptosis by suppressing p38α-mediated activation of p53 and by down-regulating p53 inhibition on p38β
      Han Liu, Ali Pedram, Jin Kyung Kim
      Cardiovascular Research 2011 89 1
    • Mitochondrial Release of Apoptosis-Inducing Factor and Cytochrome c During Smooth Muscle Cell Apoptosis
      David J. Granville, Brighid A. Cassidy, Dietrich O. Ruehlmann, Jonathan C. Choy, Catherine Brenner, Guido Kroemer, Cornelis van Breemen, Philippe Margaron, David W. Hunt, Bruce M. McManus
      The American Journal of Pathology 2001 159 1
    • Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells
      Toshinao Onoda, Takashi Ono, Dipok Kumar Dhar, Akira Yamanoi, Naofumi Nagasue
      International Journal of Cancer 2006 118 5
    • Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus
      Silke Bender, Antje Reuter, Florian Eberle, Evelyne Einhorn, Marco Binder, Ralf Bartenschlager, Glenn Randall
      PLOS Pathogens 2015 11 11
    • Apoptosis commitment – translating survival signals into decisions on mitochondria
      James A Keeble, Andrew P Gilmore
      Cell Research 2007 17 12
    • Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways
      José A Sánchez-Alcázar, Dawn A Bradbury, Linhua Pang, Alan J Knox
      Lung Cancer 2003 40 1
    • Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells by the Ganoderma lucidum and Duchesnea chrysantha extracts
      Kug Chan Kim, Jin Sik Kim, Jung Kyu Son, In Gyu Kim
      Cancer Letters 2007 246 1-2
    • Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice
      Yun K. Oh, Adi R. Bachar, David G. Zacharias, Sung Gyun Kim, Junxiang Wan, Laura J. Cobb, Lilach O. Lerman, Pinchas Cohen, Amir Lerman
      Atherosclerosis 2011 219 1
    • Nitric Oxide Induces Cell Death by Regulating Anti-Apoptotic BCL-2 Family Members
      Colleen M. Snyder, Emelyn H. Shroff, Jing Liu, Navdeep S. Chandel, Syed A. Aziz
      PLoS ONE 2009 4 9
    • Roles of p38 and JNK mitogen-activated protein kinase pathways during cantharidin-induced apoptosis in U937 cells
      Jeong-Eun Huh, Kyung-Sun Kang, Chanhee Chae, Hyung-Min Kim, Kyoo-Seok Ahn, Sung-Hoon Kim
      Biochemical Pharmacology 2004 67 10
    • Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy
      Bingshe Han, Dongkyoo Park, Rui Li, Maohua Xie, Taofeek K. Owonikoko, Guojing Zhang, Gabriel L. Sica, Chunyong Ding, Jia Zhou, Andrew T. Magis, Zhuo G. Chen, Dong M. Shin, Suresh S. Ramalingam, Fadlo R. Khuri, Walter J. Curran, Xingming Deng
      Cancer Cell 2015 27 6
    • Use of trypan blue staining to assess the quality of ovarian cryopreservation
      Patricia Fauque, Anis Ben Amor, Christiane Joanne, Germain Agnani, Jean Luc Bresson, Christophe Roux
      Fertility and Sterility 2007 87 5
    • Bcl-XLspecifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum
      Martina Klee, Felipe X. Pimentel-Muiños
      The Journal of Cell Biology 2005 168 5
    • Caspase-independent Mitochondrial Cell Death Results from Loss of Respiration, Not Cytotoxic Protein Release
      Lydia Lartigue, Yulia Kushnareva, Youngmo Seong, Helen Lin, Benjamin Faustin, Donald D. Newmeyer, Thomas D. Fox
      Molecular Biology of the Cell 2009 20 23
    • Intrinsically Disordered Proteins in Bcl-2 Regulated Apoptosis
      Gilles J. P. Rautureau, Catherine L. Day, Mark G. Hinds
      International Journal of Molecular Sciences 2010 11 4
    • Mitochondria Localization and Dimerization Are Required for CIDE-B to Induce Apoptosis
      Zhengming Chen, Ke Guo, Shen Yon Toh, Zhihong Zhou, Peng Li
      Journal of Biological Chemistry 2000 275 30
    • Synergistic Movements of Ca2+and Bax in Cells Undergoing Apoptosis
      Zui Pan, Manjunatha B. Bhat, Anna-Liisa Nieminen, Jianjie Ma
      Journal of Biological Chemistry 2001 276 34
    • Viral Bcl-2 homologs and their role in virus replication and associated diseases
      Brian M. Polster, Jonathan Pevsner, J.Marie Hardwick
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2004 1644 2-3
    • Ceramide Generated by Sphingomyelin Hydrolysis and the Salvage Pathway Is Involved in Hypoxia/Reoxygenation-induced Bax Redistribution to Mitochondria in NT-2 Cells
      Junfei Jin, Qi Hou, Thomas D. Mullen, Youssef H. Zeidan, Jacek Bielawski, Jacqueline M. Kraveka, Alicja Bielawska, Lina M. Obeid, Yusuf A. Hannun, Yi-Te Hsu
      Journal of Biological Chemistry 2008 283 39
    • Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21
      Yu-Fang Kuang, Yue-Hwa Chen
      Food and Chemical Toxicology 2004 42 10
    • Inhibition of Apoptotic Signaling Cascades Causes Loss of Trophic Factor Dependence during Neuronal Maturation
      Girish V. Putcha, Mohanish Deshmukh, Eugene M. Johnson
      The Journal of Cell Biology 2000 149 5
    • Protein Kinase Cζ Abrogates the Proapoptotic Function of Bax through Phosphorylation
      Meiguo Xin, Fengqin Gao, W. Stratford May, Tammy Flagg, Xingming Deng
      Journal of Biological Chemistry 2007 282 29
    • Regulating cell death at, on, and in membranes
      Xiaoke Chi, Justin Kale, Brian Leber, David W. Andrews
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2014 1843 9
    • Bcl-2 differentially targets K-, N-, and H-Ras to mitochondria in IL-2 supplemented or deprived cells: Implications in prevention of apoptosis
      Angelita Rebollo, Dolores Pérez-Sala, Carlos Martínez-A
      Oncogene 1999 18 35
    • Calcium Signaling Alterations, Oxidative Stress, and Autophagy in Aging
      Rodrigo Portes Ureshino, Katiucha Karolina Rocha, Guiomar Silva Lopes, Cláudia Bincoletto, Soraya Soubhi Smaili
      Antioxidants & Redox Signaling 2014 21 1
    • Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose
      Zhonghan Yang, Xuehua Mo, Qing Gong, Qiuhui Pan, Xia Yang, Weibin Cai, Chaoyang Li, Jian-xing Ma, Yunshao He, Guoquan Gao
      Apoptosis 2008 13 11
    • NADPH oxidase and apoptosis in cerulein-stimulated pancreatic acinar AR42J cells
      Ji Hoon Yu, Joo Weon Lim, Kyung Hwan Kim, Tomohiro Morio, Hyeyoung Kim
      Free Radical Biology and Medicine 2005 39 5
    • Neutropenia in type Ib glycogen storage disease
      Janice Y Chou, Hyun S Jun, Brian C Mansfield
      Current Opinion in Hematology 2010 17 1
    • Peg3/Pw1 Is a Mediator between p53 and Bax in DNA Damage-induced Neuronal Death
      Mark D. Johnson, Xiangwei Wu, Nadia Aithmitti, Richard S. Morrison
      Journal of Biological Chemistry 2002 277 25
    • Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells
      Talia Miron, Meir Wilchek, Ayala Sharp, Yoshihito Nakagawa, Makoto Naoi, Yoshinori Nozawa, Yukihiro Akao
      The Journal of Nutritional Biochemistry 2008 19 8
    • Endogenous Bax Translocation in SH-SY5Y Human Neuroblastoma Cells and Cerebellar Granule Neurons Undergoing Apoptosis
      Kim M. McGinnis, Margaret E. Gnegy, Kevin K. W. Wang
      Journal of Neurochemistry 2008 72 5
    • Ginsenoside-Rh2-Induced Mitochondrial Depolarization and Apoptosis Are Associated with Reactive Oxygen Species- and Ca2+-Mediated c-Jun NH2-Terminal Kinase 1 Activation in HeLa Cells
      Young-Mi Ham, Jin-Hee Lim, Hye-Kyung Na, Joon-Seok Choi, Byoung-Duck Park, Hyungshin Yim, Seung-Ki Lee
      Journal of Pharmacology and Experimental Therapeutics 2006 319 3
    • Hepatocyte Growth Factor Prevents Endothelial Cell Death Through Inhibition of bax Translocation From Cytosol to Mitochondrial Membrane
      H. Nakagami, R. Morishita, K. Yamamoto, Y. Taniyama, M. Aoki, K. Yamasaki, K. Matsumoto, T. Nakamura, Y. Kaneda, T. Ogihara
      Diabetes 2002 51 8
    • The N-terminal conformation of Bax regulates cell commitment to apoptosis
      J-P Upton, A J Valentijn, L Zhang, A P Gilmore
      Cell Death & Differentiation 2007 14 5
    • Apoptosis regulation in the testis: Involvement of Bcl-2 family members
      Tim L. Beumer, Hermien L. Roepers-Gajadien, Iris S. Gademan, Tycho M.T.W. Lock, Henk B. Kal, Dirk G. De Rooij
      Molecular Reproduction and Development 2000 56 3
    • BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide–induced cell death in myeloma
      Alejo A. Morales, Delia Gutman, Kelvin P. Lee, Lawrence H. Boise
      Blood 2008 111 10
    • Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat
      B. Puig, I. Ferrer
      Neuroscience Letters 2002 321 3
    • Expression of human IAP-like protein in skeletal muscle: a possible explanation for the rare incidence of muscle fiber apoptosis in T-cell mediated inflammatory myopathies
      Mian Li, Marinos C. Dalakas
      Journal of Neuroimmunology 2000 106 1-2
    • Neuroprotectin D1 Induces Dephosphorylation of Bcl-xLin a PP2A-dependent Manner during Oxidative Stress and Promotes Retinal Pigment Epithelial Cell Survival
      Rajee Antony, Walter J. Lukiw, Nicolas G. Bazan
      Journal of Biological Chemistry 2010 285 24
    • The Vaccinia Virus Protein F1L Interacts with Bim and Inhibits Activation of the Pro-apoptotic Protein Bax
      John M. Taylor, Douglas Quilty, Logan Banadyga, Michele Barry
      Journal of Biological Chemistry 2006 281 51
    • Vitamin E
      Paul W. Sylvester
      2007 76
    • Advances in Immunology Volume 70
      Andy J. Minn, Rachel E. Swain, Averil Ma, Craig B. Thompson
      1998 70
    • Intersectin-1s Regulates the Mitochondrial Apoptotic Pathway in Endothelial Cells
      Sanda A. Predescu, Dan N. Predescu, Ivana Knezevic, Irene K. Klein, Asrar B. Malik
      Journal of Biological Chemistry 2007 282 23
    • Apoptosis commitment and activation of mitochondrial Bax during anoikis is regulated by p38MAPK
      T W Owens, A J Valentijn, J-P Upton, J Keeble, L Zhang, J Lindsay, N K Zouq, A P Gilmore
      Cell Death & Differentiation 2009 16 11
    • Lipopolysaccharide induces apoptotic insults to human alveolar epithelial A549 cells through reactive oxygen species-mediated activation of an intrinsic mitochondrion-dependent pathway
      Chi-Yuan Chuang, Ta-Liang Chen, Yih-Giun Cherng, Yu-Tyng Tai, Tyng-Guey Chen, Ruei-Ming Chen
      Archives of Toxicology 2011 85 3
    • pH-Triggered Conformational Switching along the Membrane Insertion Pathway of the Diphtheria Toxin T-Domain
      Alexey Ladokhin
      Toxins 2013 5 8
    • Bcl-2, Bax and Bcl-x expression following kainic acid administration at convulsant doses in the rat
      E. López, E. Pozas, R. Rivera, I. Ferrer
      Neuroscience 1999 91 4
    • Death upon a Kiss: Mitochondrial Outer Membrane Composition and Organelle Communication Govern Sensitivity to BAK/BAX-Dependent Apoptosis
      Thibaud T. Renault, Jerry E. Chipuk
      Chemistry & Biology 2014 21 1
    • IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation
      Giovanni Benard, Albert Neutzner, Guihong Peng, Chunxin Wang, Ferenc Livak, Richard J Youle, Mariusz Karbowski
      The EMBO Journal 2010 29 8
    • Oxidative and nitrosative stress pathways in the brain of socially isolated adult male rats demonstrating depressive- and anxiety-like symptoms
      Dragana Filipović, Nevena Todorović, Rick E. Bernardi, Peter Gass
      Brain Structure and Function 2017 222 1
    • Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia
      Feng-Ting Liu, Adrian C Newland, Li Jia
      Biochemical and Biophysical Research Communications 2003 310 3
    • Increase in PGE2 biosynthesis induces a Bax dependent apoptosis correlated to patients’ survival in glioblastoma multiforme
      L Lalier, P-F Cartron, F Pedelaborde, C Olivier, D Loussouarn, S A Martin, K Meflah, J Menanteau, F M Vallette
      Oncogene 2007 26 34
    • Oxidized low-density lipoprotein induces apoptotic insults to mouse cerebral endothelial cells via a Bax–mitochondria–caspase protease pathway
      Tyng-Guey Chen, Ta-Liang Chen, Huai-Chia Chang, Yu-Ting Tai, Yih-Giun Cherng, Ya-Ting Chang, Ruei-Ming Chen
      Toxicology and Applied Pharmacology 2007 219 1
    • Pro-apoptotic and anti-proliferative effects of mitofusin-2 via Bax signaling in hepatocellular carcinoma cells
      Weilin Wang, Jianju Lu, Feng Zhu, Jianfeng Wei, Changku Jia, Yuanbiao Zhang, Lin Zhou, Haiyang Xie, Shusen Zheng
      Medical Oncology 2012 29 1
    • Therapeutic Efficacy of PUMA for Malignant Glioma Cells Regardless of p53 Status
      Hideaki Ito, Takao Kanzawa, Toru Miyoshi, Satoshi Hirohata, Satoru Kyo, Arifumi Iwamaru, Hiroshi Aoki, Yasuko Kondo, Seiji Kondo
      Human Gene Therapy 2005 16 6
    • Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation
      Z Cai, M Lin, C Wuchter, V Ruppert, B Dörken, W-D Ludwig, L Karawajew
      Leukemia 2001 15 4
    • Bax and caspases are inhibited by endogenous nitric oxide in dorsal root ganglion neuronsin vitro
      T. Thippeswamy, J. S. McKay, R. Morris
      European Journal of Neuroscience 2001 14 8
    • Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1
      Irene M. Pedersen, Shinichi Kitada, Lorenzo M. Leoni, Juan M. Zapata, James G. Karras, Nobuhiro Tsukada, Thomas J. Kipps, Yong Sung Choi, Frank Bennett, John C. Reed
      Blood 2002 100 5
    • Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency
      P. Tandon, C. A. Gallo, S. Khatri, J. F. Barger, H. Yepiskoposyan, D. R. Plas
      Proceedings of the National Academy of Sciences 2011 108 6
    • Simian Virus 40 Large T Antigen Binds a Novel Bcl-2 Homology Domain 3-containing Proapoptosis Protein in the Cytoplasm
      Shih-Chong Tsai, Kishore B. S. Pasumarthi, Laura Pajak, Michael Franklin, Brian Patton, He Wang, William J. Henzel, John T. Stults, Loren J. Field
      Journal of Biological Chemistry 2000 275 5
    • An association of Bcl-2 phosphorylation and Bax localization with their functions after hyperthermia and paclitaxel treatment
      Alaa-eldin Salah-eldin, Shoichi Inoue, Shigeki Tsukamoto, Hiromi Aoi, Masumi Tsuda
      International Journal of Cancer 2003 103 1
    • BCL-2 proteins and apoptosis: Recent insights and unknowns
      Frank Edlich
      Biochemical and Biophysical Research Communications 2018 500 1
    • BM-1197: A Novel and Specific Bcl-2/Bcl-xL Inhibitor Inducing Complete and Long-Lasting Tumor Regression In Vivo
      Longchuan Bai, Jianfang Chen, Donna McEachern, Liu Liu, Haibin Zhou, Angelo Aguilar, Shaomeng Wang, Justin L. Mott
      PLoS ONE 2014 9 6
    • Bax translocates from cytosol to mitochondria in cardiac cells during apoptosis: development of a GFP-Bax-stable H9c2 cell line for apoptosis analysis
      Qi Hou, Yi-Te Hsu
      American Journal of Physiology-Heart and Circulatory Physiology 2005 289 1
    • Bax-mediated apoptosis in the livers of rats after partial hepatectomy in the retrorsine model of hepatocellular injury
      Gavin J. Gordon, William B. Coleman, Joe W. Grisham
      Hepatology 2000 32 2
    • Calcium and cell death signaling in neurodegeneration and aging
      Soraya Smaili, Hanako Hirata, Rodrigo Ureshino, Priscila T. Monteforte, Ana P. Morales, Mari L. Muler, Juliana Terashima, Karen Oseki, Tatiana R. Rosenstock, Guiomar S. Lopes, Claudia Bincoletto
      Anais da Academia Brasileira de Ciências 2009 81 3
    • Death and Survival Signals Determine Active/Inactive Conformations of Pro-apoptotic BAX, BAD, and BID Molecules
      S.J. KORSMEYER, A. GROSS, H. HARADA, J. ZHA, K. WANG, X.-M. YIN, M. WEI, S. ZINKEL
      Cold Spring Harbor Symposia on Quantitative Biology 1999 64
    • Vitamin E blocks early events induced by 1-methyl-4-phenylpyridinium (MPP+) in cerebellar granule cells
      Rosa A. González-Polo, Germán Soler, Alberto Alvarez, Isabel Fabregat, José M. Fuentes
      Journal of Neurochemistry 2003 84 2
    • After Embedding in Membranes Antiapoptotic Bcl-XL Protein Binds Both Bcl-2 Homology Region 3 and Helix 1 of Proapoptotic Bax Protein to Inhibit Apoptotic Mitochondrial Permeabilization
      Jingzhen Ding, Blaine H. M. Mooers, Zhi Zhang, Justin Kale, Domina Falcone, Jamie McNichol, Bo Huang, Xuejun C. Zhang, Chengguo Xing, David W. Andrews, Jialing Lin
      Journal of Biological Chemistry 2014 289 17
    • Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum
      C Gajate, M Matos-da-Silva, E L-H Dakir, R I Fonteriz, J Alvarez, F Mollinedo
      Oncogene 2012 31 21
    • Involvement of Bik, a Proapoptotic Member of the Bcl-2 Family, in Surface IgM-Mediated B Cell Apoptosis
      Aimin Jiang, Edward A. Clark
      The Journal of Immunology 2001 166 10
    • Mitochondria, glutamate neurotoxicity and the death cascade
      M. Montal
      Biochimica et Biophysica Acta (BBA) - Bioenergetics 1998 1366 1-2
    • Mitochondrion-targeted apoptosis regulators of viral origin
      Patricia Boya, Thomas Roumier, Karine Andreau, Rosa-Ana Gonzalez-Polo, Naoufal Zamzami, Maria Castedo, Guido Kroemer
      Biochemical and Biophysical Research Communications 2003 304 3
    • Molecular Regulation of DNA Damage-Induced Apoptosis in Neurons of Cerebral Cortex
      L. J. Martin, Z. Liu, J. Pipino, B. Chestnut, M. A. Landek
      Cerebral Cortex 2009 19 6
    • Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway
      E López, I Ferrer
      Molecular Brain Research 2000 85 1-2
    • Apoptosis-Linked Gene 2 Binds to the Death Domain of Fas and Dissociates from Fas during Fas-Mediated Apoptosis in Jurkat Cells
      Yong-Sam Jung, Keun-Soo Kim, Kwang Dong Kim, Jong-Seok Lim, Jung-Woo Kim, Eunhee Kim
      Biochemical and Biophysical Research Communications 2001 288 2
    • BAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells
      Margaret E. Maes, Cassandra L. Schlamp, Robert W. Nickells
      Progress in Retinal and Eye Research 2017 57
    • BCL-2 Protein Family
      Maria Eugenia Soriano, Luca Scorrano
      2010 687
    • BCL-xL-Dependent Light Scattering by Apoptotic Cells
      Nada N. Boustany, Yien-Che Tsai, Bryan Pfister, Wilsaan M. Joiner, George A. Oyler, Nitish V. Thakor
      Biophysical Journal 2004 87 6
    • Crosstalk between Raf/MEK/ERK and PI3K/AKT in Suppression of Bax Conformational Change by Grp75 under Glucose Deprivation Conditions
      Ling Yang, Weiwei Guo, Qunling Zhang, Hongyan Li, Xiaoyu Liu, Yunlong Yang, Ji Zuo, Wen Liu
      Journal of Molecular Biology 2011 414 5
    • Hepatitis B virus X protein induces apoptosis by enhancing translocation of Bax to mitochondria
      Hye Jin Kim, Sang Yong Kim, Jinchul Kim, Heemin Lee, Misun Choi, Jeong Ki Kim, Jeong Keun Ahn
      IUBMB Life 2008 60 7
    • Interleukin-3 Induces the Phosphorylation of a Distinct Fraction of Bcl-2
      Paul B. Poommipanit, Bin Chen, Zoltán N. Oltvai
      Journal of Biological Chemistry 1999 274 2
    • Structural Insights of tBid, the Caspase-8-activated Bid, and Its BH3Domain
      Yu Wang, Nico Tjandra
      Journal of Biological Chemistry 2013 288 50
    • tBid Elicits a Conformational Alteration in Membrane-bound Bcl-2 Such That It Inhibits Bax Pore Formation
      Jun Peng, Chibing Tan, G. Jane Roberts, Olga Nikolaeva, Zhi Zhang, Suzanne M. Lapolla, Steve Primorac, David W. Andrews, Jialing Lin
      Journal of Biological Chemistry 2006 281 47
    • CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation
      Y Liu, H V Clegg, P L Leslie, J Di, L A Tollini, Y He, T-H Kim, A Jin, L M Graves, J Zheng, Y Zhang
      Cell Death & Differentiation 2015 22 6
    • Caspase-Mediated Proteolytic Activation of Calcineurin in Thapsigargin-Mediated Apoptosis in SH-SY5Y Neuroblastoma Cells
      Neeta Mukerjee, Kim M. McGinnis, Yang Hae Park, Margaret E. Gnegy, Kevin K.W. Wang
      Archives of Biochemistry and Biophysics 2000 379 2
    • Involvement of Bax Protein in the Prevention of Glucocorticoid-Induced Thymocytes Apoptosis by Melatonin
      Esteban Hoijman, Luciana Rocha Viegas, María Inés Keller Sarmiento, Ruth E. Rosenstein, Adali Pecci
      Endocrinology 2004 145 1
    • Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells
      Wilaiwan Wisessmith, Pansiri Phansuwan-Pujito, Piyarat Govitrapong, Banthit Chetsawang
      Journal of Pineal Research 2009 46 4
    • The C-Terminus of bax Is Not a Membrane Addressing/Anchoring Signal
      Karine Tremblais, Lisa Oliver, Philippe Juin, Marie Thérese Le Cabellec, Khaled Meflah, François M. Vallette
      Biochemical and Biophysical Research Communications 1999 260 3
    • The secret life of Bcl-2: Apoptosis-independent inhibition of DNA repair by Bcl-2 family members
      Corentin Laulier, Bernard S. Lopez
      Mutation Research/Reviews in Mutation Research 2012 751 2
    • Tocotrienol-induced cytotoxicity is unrelated to mitochondrial stress apoptotic signaling in neoplastic mammary epithelial cells
      Sumit J Shah, Paul W Sylvester
      Biochemistry and Cell Biology 2005 83 1
    • Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins
      Saeid Ghavami, Pawan Sharma, Behzad Yeganeh, Oluwaseun O. Ojo, Aruni Jha, Mark M. Mutawe, Hessam H. Kashani, Marek J. Los, Thomas Klonisch, Helmut Unruh, Andrew J. Halayko
      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2014 1843 7
    • Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons
      Isabelle Martinou, Marc Missotten, Pierre-Alain Fernandez, Rémy Sadoul, Jean-Claude Martinou
      NeuroReport 1998 9 1
    • Bax targeting to mitochondria occurs via both tail anchor-dependent and -independent mechanisms
      A J Valentijn, J-P Upton, N Bates, A P Gilmore
      Cell Death & Differentiation 2008 15 8
    • Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A
      Woen Ping Siu, Pamela Boon Li Pun, Calivarathan Latchoumycandane, Urs A. Boelsterli
      Toxicology and Applied Pharmacology 2008 227 3
    • Conformation of BCL-XL upon Membrane Integration
      Yong Yao, Lynn M. Fujimoto, Nathan Hirshman, Andrey A. Bobkov, Antonella Antignani, Richard J. Youle, Francesca M. Marassi
      Journal of Molecular Biology 2015 427 13
    • Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway
      Ying Zhang, Meng Luo, Yuangang Zu, Yujie Fu, Chengbo Gu, Wei Wang, Liping Yao, Thomas Efferth
      Chemico-Biological Interactions 2012 199 2
    • Evidence that Membrane Insertion of the Cytosolic Domain of Bcl-xL is Governed by an Electrostatic Mechanism
      Guruvasuthevan R. Thuduppathy, Jeffrey W. Craig, Victoria Kholodenko, Arne Schon, R. Blake Hill
      Journal of Molecular Biology 2006 359 4
    • Molecular and Cellular Biology of Neuroprotection in the CNS
      Richard S. Morrison, Yoshito Kinoshita, Mark D. Johnson, Saadi Ghatan, Joseph T. Ho, Gwenn Garden
      2003 513
    • Nuclear Translocation and Increased Expression of Bax and Disturbance in Cell Cycle Progression without Prominent Apoptosis Induced by Hyperthermia
      Michiru Nishita, Shoichi Inoue, Masumi Tsuda, Chie Tateda, Toshiyuki Miyashita
      Experimental Cell Research 1998 244 1
    • Overexpression of Bcl-XL prevents caspase-3-mediated activation of DNA fragmentation factor (DFF) produced by treatment with the photochemotherapeutic agent BPD-MA
      David J Granville, Huijun Jiang, Mary T An, Julia G Levy, Bruce M McManus, David W.C Hunt
      FEBS Letters 1998 422 2
    • Role of Mitofusin 2 in the Renal Stress Response
      Jonathan M. Gall, Zhiyong Wang, Marc Liesa, Anthony Molina, Andrea Havasi, John H. Schwartz, Orian Shirihai, Steven C. Borkan, Ramon G. B. Bonegio, Alicia J. Kowaltowski
      PLoS ONE 2012 7 1
    • Bax affects intracellular Ca2+ stores and induces Ca2+ wave propagation
      A C P Carvalho, J Sharpe, T R Rosenstock, A F V Teles, A J Kowaltowski, R J Youle, S S Smaili
      Cell Death & Differentiation 2004 11 12
    • Bcl-2, via Its BH4 Domain, Blocks Apoptotic Signaling Mediated by Mitochondrial Ras
      Gerald V. Denis, Qiang Yu, Peihong Ma, Linda Deeds, Douglas V. Faller, Chang-Yan Chen
      Journal of Biological Chemistry 2003 278 8
    • Deficiency of the Bax gene attenuates denervation-induced apoptosis
      P. M. Siu, S. E. Alway
      Apoptosis 2006 11 6
    • Elucidation of some Bax conformational changes through crystallization of an antibody–peptide complex
      F W Peyerl, S Dai, G A Murphy, F Crawford, J White, P Marrack, J W Kappler
      Cell Death & Differentiation 2007 14 3
    • Impact of pH on Bax α conformation, oligomerisation and mitochondrial integration
      Pierre François Cartron, Lisa Oliver, Ebrahim Mayat, Khaled Meflah, François M. Vallette
      FEBS Letters 2004 578 1-2
    • Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria
      N. Y. Fu, S. K. Sukumaran, V. C. Yu
      Proceedings of the National Academy of Sciences 2007 104 24
    • Initiation of mitochondrial-mediated apoptosis during cardiac reperfusion
      Kathleen Corrigan Lundberg, Luke I. Szweda
      Archives of Biochemistry and Biophysics 2004 432 1
    • S29 ribosomal protein induces apoptosis in H520 cells and sensitizes them to chemotherapy
      Neeru Khanna, Sudip Sen, Himani Sharma, Neeta Singh
      Biochemical and Biophysical Research Communications 2003 304 1
    • Antisense bcl-2 treatment increases programmed cell death in non-small cell lung cancer cell lines
      Patrick P. Koty, Haifan Zhang, Mark L. Levitt
      Lung Cancer 1999 23 2
    • Expression and Purification of Full-Length Human Bax α
      Sylvie Montessuit, Gonzalo Mazzei, Edith Magnenat, Bruno Antonsson
      Protein Expression and Purification 1999 15 2
    • Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells
      Ricky Malhotra, David W Tyson, Henry M Rosevear, Frank C Brosius
      BMC Cardiovascular Disorders 2008 8 1
    • Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line
      Deepti Chopra, Lipika Ray, Ashish Dwivedi, Shashi Kant Tiwari, Jyoti Singh, Krishna P. Singh, Hari Narayan Kushwaha, Sadaf Jahan, Ankita Pandey, Shailendra K. Gupta, Rajnish Kumar Chaturvedi, Aditya Bhushan Pant, Ratan Singh Ray, Kailash Chand Gupta
      Biomaterials 2016 84
    • Role of reactive oxygen species and Bax in oxidized low density lipoprotein-induced apoptosis of human monocytes
      Natalia Ermak, Bernard Lacour, Tilman B. Drüeke, Stéphanie Vicca
      Atherosclerosis 2008 200 2
    • Thymoquinone Induces Mitochondria-Mediated Apoptosis in Acute Lymphoblastic Leukaemia in Vitro
      Landa Salim, Syam Mohan, Rozana Othman, Siddig Abdelwahab, Behnam Kamalidehghan, Bassem Sheikh, Mohamed Ibrahim
      Molecules 2013 18 9
    • Tumor Suppressor p53 Mediates Apoptotic Cell Death Triggered by Cyclosporin A
      Beata Pyrzynska, Manuel Serrano, Carlos Martı́nez-A., Bozena Kaminska
      Journal of Biological Chemistry 2002 277 16
    • A1/Bfl-1 in leukocyte development and cell death
      Eleonora Ottina, Denise Tischner, Marco J. Herold, Andreas Villunger
      Experimental Cell Research 2012 318 11
    • Geniposidic acid protects against d-galactosamine and lipopolysaccharide-induced hepatic failure in mice
      So-Jin Kim, Kang-Min Kim, Juhyun Park, Jong-Hwan Kwak, Yeong Shik Kim, Sun-Mee Lee
      Journal of Ethnopharmacology 2013 146 1
    • Gonadotropin-Releasing Hormone Antagonist Antide Inhibits Apoptosis of Preovulatory Follicle Cells in Rat Ovary1
      Fernanda Parborell, Griselda Irusta, Alejandra Vitale, Olga Gonzalez, Adalí Pecci, Marta Tesone
      Biology of Reproduction 2005 72 3
    • How does the Bax-α1 targeting sequence interact with mitochondrial membranes? The role of cardiolipin
      Marc-Antoine Sani, Erick J. Dufourc, Gerhard Gröbner
      Biochimica et Biophysica Acta (BBA) - Biomembranes 2009 1788 3
    • Insights into the mechanisms of CMV-mediated interference with cellular apoptosis
      Christopher E Andoniou, Mariapia A Degli-Esposti
      Immunology and Cell Biology 2006 84 1
    • Insulin-like growth factor-1 protects peroxynitrite-induced cell death by preventing cytochromec-induced caspase-3 activation
      Makio Saeki, Sadaaki Maeda, Kouichirou Wada, Yoshinori Kamisaki
      Journal of Cellular Biochemistry 2002 84 4
    • Microglia Are Mediators of Borrelia burgdorferi–Induced Apoptosis in SH-SY5Y Neuronal Cells
      Tereance A. Myers, Deepak Kaushal, Mario T. Philipp, Jenifer Coburn
      PLoS Pathogens 2009 5 11
    • Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis
      Qi Hou, Junfei Jin, Hui Zhou, Sergei A. Novgorodov, Alicja Bielawska, Zdzislaw M. Szulc, Yusuf A. Hannun, Lina M. Obeid, Yi-Te Hsu
      Journal of Lipid Research 2011 52 2
    • Direct addition of BimL to mitochondria does not lead to cytochromecrelease
      Olivier Terradillos, Sylvie Montessuit, David C.S Huang, Jean-Claude Martinou
      FEBS Letters 2002 522 1-3
    • Expression of p53 protein and the apoptotic regulatory molecules Bcl-2, Bcl-XL, and Bax in locally advanced squamous cell carcinoma of the lung
      Mir Snober Shabnam, Radhika Srinivasan, Anjlina Wali, Siddhartha Majumdar, Kusum Joshi, Digambar Behera
      Lung Cancer 2004 45 2
    • Lycium barbarum Polysaccharide Prevents Focal Cerebral Ischemic Injury by Inhibiting Neuronal Apoptosis in Mice
      Tengfei Wang, Yuxiang Li, Yongsheng Wang, Ru Zhou, Lin Ma, Yinju Hao, Shaoju Jin, Juan Du, Chengjun Zhao, Tao Sun, Jianqiang Yu, Thiruma V. Arumugam
      PLoS ONE 2014 9 3
    • Praf2 Is a Novel Bcl-xL/Bcl-2 Interacting Protein with the Ability to Modulate Survival of Cancer Cells
      Maria Teresa Vento, Valeria Zazzu, Alessia Loffreda, Justin R. Cross, Julian Downward, Maria Patrizia Stoppelli, Ingram Iaccarino, Rafael Linden
      PLoS ONE 2010 5 12
    • Blocking Angiotensin II Type 1 Receptor Triggers Apoptotic Cell Death in Human Pancreatic Cancer Cells
      Qiaoke Gong, Molly Davis, Galina Chipitsyna, Charles J. Yeo, Hwyda A. Arafat
      Pancreas 2010 39 5
    • G-CSF improves murine G6PC3-deficient neutrophil function by modulating apoptosis and energy homeostasis
      Hyun Sik Jun, Young Mok Lee, Ki Duk Song, Brian C. Mansfield, Janice Y. Chou
      Blood 2011 117 14
    • Redistribution of Bax from Cytosol to Membranes Is Induced by Apoptotic Stimuli and Is an Early Step in the Apoptotic Pathway
      Hong Zhang, Jutta Heim, Bernd Meyhack
      Biochemical and Biophysical Research Communications 1998 251 2
    • The Anti-Apoptotic Bcl-xL Protein, a New Piece in the Puzzle of Cytochrome C Interactome
      Ivano Bertini, Soizic Chevance, Rebecca Del Conte, Daniela Lalli, Paola Turano, Pierandrea Temussi
      PLoS ONE 2011 6 4
    • Yessotoxin as an apoptotic inducer
      Mónica Suárez Korsnes, Arild Espenes
      Toxicon 2011 57 7-8
    • Bid is not required for Bax translocation during UV-induced apoptosis
      Yinyuan Wu, Da Xing, Wei R. Chen, Xichao Wang
      Cellular Signalling 2007 19 12
    • Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes
      Jeong-Yeh Yang, Mary Anne Della-Fera, Clifton A. Baile
      Apoptosis 2006 11 8
    • Molecular mechanisms of sulfasalazine-induced T-cell apoptosis
      Susanne Liptay, Simone Fulda, Marta Schanbacher, Soizic Bourteele, Karine F Ferri, Guido Kroemer, Guido Adler, Klaus M Debatin, Roland M Schmid
      British Journal of Pharmacology 2002 137 5
    • Supercritical Carbon Dioxide Extraction of Aromatic Turmerone from Curcuma longa Linn. Induces Apoptosis through Reactive Oxygen Species-Triggered Intrinsic and Extrinsic Pathways in Human Hepatocellular Carcinoma HepG2 Cells
      Shao-Bin Cheng, Li-Chen Wu, Yun-Chih Hsieh, Chi-Hao Wu, Yu-Ju Chan, Li-Hsun Chang, Chieh-Ming J. Chang, Shih-Lan Hsu, Chieh-Lin Teng, Chun-Chi Wu
      Journal of Agricultural and Food Chemistry 2012 60 38
    • The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation
      Joachim Lauterwasser, Franziska Todt, Ralf M. Zerbes, Thanh Ngoc Nguyen, William Craigen, Michael Lazarou, Martin van der Laan, Frank Edlich
      Scientific Reports 2016 6 1
    • The substitution of the C-terminus of bax by that of bcl-xL does not affect its subcellular localization but abrogates its pro-apoptotic properties
      Lisa Oliver, Muriel Priault, Karine Tremblais, Marie-Thérèse LeCabellec, Khaled Meflah, Stéphen Manon, Francois M Vallette
      FEBS Letters 2000 487 2
    • pH-Triggered Conformational Switching of the Diphtheria Toxin T-Domain: The Roles of N-Terminal Histidines
      Igor V. Kurnikov, Alexander Kyrychenko, Jose C. Flores-Canales, Mykola V. Rodnin, Nikolay Simakov, Mauricio Vargas-Uribe, Yevgen O. Posokhov, Maria Kurnikova, Alexey S. Ladokhin
      Journal of Molecular Biology 2013 425 15
    • Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak
      D Neise, V Graupner, B F Gillissen, P T Daniel, K Schulze-Osthoff, R U Jänicke, F Essmann
      Oncogene 2008 27 10
    • An Internal EELD Domain Facilitates Mitochondrial Targeting of Mcl-1 via a Tom70-dependent Pathway
      Chiang-Hung Chou, Ru-Shuo Lee, Hsin-Fang Yang-Yen, Janet Shaw
      Molecular Biology of the Cell 2006 17 9
    • Bax Contains Two Functional Mitochondrial Targeting Sequences and Translocates to Mitochondria in a Conformational Change- and Homo-oligomerization-driven Process
      Nicholas M. George, Natalie Targy, Jacquelynn J. D. Evans, Liqiang Zhang, Xu Luo
      Journal of Biological Chemistry 2010 285 2
    • Bcl-w(edding) with mitochondria
      Thomas Kaufmann, Anna Schinzel, Christoph Borner
      Trends in Cell Biology 2004 14 1
    • Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis
      Colins O. Eno, Emily F. Eckenrode, Kristen E. Olberding, Guoping Zhao, Carl White, Chi Li, Donald D. Newmeyer
      Molecular Biology of the Cell 2012 23 13
    • Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2
      A Dunkle, I Dzhagalov, Y-W He
      Cell Death & Differentiation 2010 17 6
    • MicroRNA-181c targets Bcl-2 and regulates mitochondrial morphology in myocardial cells
      Hongjiang Wang, Jing Li, Hongjie Chi, Fan Zhang, Xiaoming Zhu, Jun Cai, Xinchun Yang
      Journal of Cellular and Molecular Medicine 2015 19 9
    • Pien Tze Huang (片仔癀)-induced apoptosis in human colon cancer HT-29 cells is associated with regulation of the Bcl-2 family and activation of caspase 3
      Jiu-mao Lin, Li-hui Wei, You-qin Chen, Xian-xiang Liu, Zhen-feng Hong, Thomas J. Sferra, Jun Peng
      Chinese Journal of Integrative Medicine 2011 17 9
    • Testosterone exerts antiapoptotic effects against H2O2 in C2C12 skeletal muscle cells through the apoptotic intrinsic pathway
      Lucía Pronsato, Ricardo Boland, Lorena Milanesi
      Journal of Endocrinology 2012 212 3
    • The p53-activated Gene, PAG608, Requires a Zinc Finger Domain for Nuclear Localization and Oxidative Stress-induced Apoptosis
      Youichirou Higashi, Masato Asanuma, Ikuko Miyazaki, M. Emdadul Haque, Naoko Fujita, Ken-ichi Tanaka, Norio Ogawa
      Journal of Biological Chemistry 2002 277 44
    • The role of SERCA2a/PLN complex, Ca2+ homeostasis, and anti-apoptotic proteins in determining cell fate
      Elizabeth Vafiadaki, Vasiliki Papalouka, Demetrios A. Arvanitis, Evangelia G. Kranias, Despina Sanoudou
      Pflügers Archiv - European Journal of Physiology 2009 457 3
    • A primate-specific POTE-actin fusion protein plays a role in apoptosis
      Xiu Fen Liu, Tapan K. Bera, Lisa J. Liu, Ira Pastan
      Apoptosis 2009 14 10
    • Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction
      H Ikemoto, E Tani, I Ozaki, H Kitagawa, N Arita
      Cell Death & Differentiation 2000 7 6
    • Estrogen Induces Global Reorganization of Chromatin Structure in Human Breast Cancer Cells
      Raphaël Mourad, Pei-Yin Hsu, Liran Juan, Changyu Shen, Prasad Koneru, Hai Lin, Yunlong Liu, Kenneth Nephew, Tim H. Huang, Lang Li, Wei Xu
      PLoS ONE 2014 9 12
    • From sentencing to execution – the processes of apoptosis
      Kelly L. Moffitt, S. Lorraine Martin, Brian Walker
      Journal of Pharmacy and Pharmacology 2010 62 5
    • Proteins Membrane Binding and Pore Formation
      Ana J. García-Sáez, Gustavo Fuertes, Jacob Suckale, Jesús Salgado
      2010 677
    • Re-Engineering of the Damaged Brain and Spinal Cord
      M. Pizzi, I. Sarnico, F. Boroni, A. Benetti, M. Benarese, P. F. Spano
      2005 93
    • Characterization of the execution pathway of developing motoneurons deprived of trophic support
      Ling Li, Ronald W. Oppenheim, Carolanne E. Milligan
      Journal of Neurobiology 2001 46 4
    • Detection of Bax protein conformational change using a surface plasmon resonance imaging-based antibody chip
      Moonil Kim, Sun Ok Jung, Kyoungsook Park, Eun-Ju Jeong, Hyou-Arm Joung, Tae-Hyoung Kim, Dai-Wu Seol, Bong Hyun Chung
      Biochemical and Biophysical Research Communications 2005 338 4
    • Glucose-regulated protein 75 suppresses apoptosis induced by glucose deprivation in PC12 cells through inhibition of Bax conformational change
      Ling Yang, Xiaoyu Liu, Jinyu Hao, Yunlong Yang, Mingxia Zhao, Ji Zuo, Wen Liu
      Acta Biochimica et Biophysica Sinica 2008 40 4
    • Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies
      Sweta Iyer, Khatira Anwari, Amber E. Alsop, Wai Shan Yuen, David C. S. Huang, John Carroll, Nicholas A. Smith, Brian J. Smith, Grant Dewson, Ruth M. Kluck
      Nature Communications 2016 7 1
    • Interferon-induced Upregulation and Cytoplasmic Localization of Myc-Interacting Protein Nmi
      STEWART J. LEBRUN, REBECCA L. SHPALL, LOUIE NAUMOVSKI
      Journal of Interferon & Cytokine Research 1998 18 9
    • PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes
      Sadamitsu Asoh, Shigeo Ohta
      Advanced Drug Delivery Reviews 2008 60 4-5
    • Role of tumour necrosis factor receptor-1 and nuclear factor-κB in production of TNF-α-induced pro-inflammatory microparticles in endothelial cells
      Sung Kyul Lee, Seung-Hee Yang, Il Kwon, Ok-Hee Lee, Ji Hoe Heo
      Thrombosis and Haemostasis 2014 112 09
    • Sera of Patients With Celiac Disease and Neurologic Disorders Evoke a Mitochondrial-Dependent Apoptosis In Vitro
      Elisabetta Cervio, Umberto Volta, Manuela Verri, Federica Boschi, Ornella Pastoris, Alessandro Granito, Giovanni Barbara, Claudia Parisi, Cristina Felicani, Marcello Tonini, Roberto De Giorgio
      Gastroenterology 2007 133 1
    • The cytoprotective peptide humanin is induced and neutralizes Bax after pro-apoptotic stress in the rat testis
      Y. Jia, Y.-H. Lue, R. Swerdloff, K.-W. Lee, L. J. Cobb, P. Cohen, C. Wang
      Andrology 2013 1 4
    • The effect of the red wine polyphenol resveratrol on a rat model of biliary obstructed cholestasis: involvement of anti-apoptotic signalling, mitochondrial biogenesis and the induction of autophagy
      Tsu-Kung Lin, Li-Tung Huang, Ying-Hsien Huang, Mao-Meng Tiao, Kuo-Shu Tang, Chia-Wei Liou
      Apoptosis 2012 17 8
    • A selection system for human apoptosis inhibitors using yeast
      William Greenhalf, Janet Lee, Bhabatosh Chaudhuri
      Yeast 1999 15 13
    • Activation of apoptotic protein in U937 cells by a component of turmeric oil
      Yong-Kyu Lee
      BMB Reports 2009 42 2
    • Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729
      Amy L. Grenier, Khaled Abu-ihweij, Ge Zhang, Shannon Moore Ruppert, Rebecca Boohaker, Emily R. Slepkov, Kathryn Pridemore, Jian-Jian Ren, Larry Fliegel, Annette R. Khaled
      American Journal of Physiology-Cell Physiology 2008 295 4
    • Bax Activation by Engagement with, Then Release from, the BH3 Binding Site of Bcl-xL
      F. Gautier, Y. Guillemin, P. F. Cartron, T. Gallenne, N. Cauquil, T. Le Diguarher, P. Casara, F. M. Vallette, S. Manon, J. A. Hickman, O. Geneste, P. Juin
      Molecular and Cellular Biology 2011 31 4
    • Characterization of Bax-ς, a Cell Death-Inducing Isoform of Bax
      Estelle Schmitt, Claudie Paquet, Myriam Beauchemin, Jessica Dever-Bertrand, Richard Bertrand
      Biochemical and Biophysical Research Communications 2000 270 3
    • Elevated Bcl-XL levels correlate with T cell survival in multiple sclerosis
      Sonia Waiczies, Alexandra Weber, Jan D. Lünemann, Orhan Aktas, Rolf Zschenderlein, Frauke Zipp
      Journal of Neuroimmunology 2002 126 1-2
    • Functional mechanisms of apoptosis-related proteins in neonatal rat cerebellum are differentially influenced by ethanol at postnatal days 4 and 7
      Kendra I. Siler-Marsiglio, Michael Paiva, Irina Madorsky, Qun Pan, Gerry Shaw, Marieta B. Heaton
      Journal of Neuroscience Research 2005 81 5
    • Increased DNA fragmentation and altered apoptotic protein levels in skeletal muscle of spontaneously hypertensive rats
      Joe Quadrilatero, James W. E. Rush
      Journal of Applied Physiology 2006 101 4
    • Regulation of Bcl2 Phosphorylation and Potential Significance for Leukemic Cell Chemoresistance
      X. Deng, S. M. Kornblau, P. P. Ruvolo, W. S. May
      JNCI Monographs 2000 2000 28
    • Bcl-rambo beta, a special splicing variant with an insertion of an Alu-like cassette, promotes etoposide- and Taxol-induced cell death
      Peng Yi, Wei Zhang, Zhiwei Zhai, Lin Miao, Yi Wang, Mian Wu
      FEBS Letters 2003 534 1-3
    • CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway
      Emmanuelle Boisvieux-Ulrich, Matthieu Sourdeval, Francelyne Marano
      Experimental Cell Research 2005 307 1
    • Cytosolic Bax
      Sandra Vogel, Nina Raulf, Stephanie Bregenhorn, Martin L. Biniossek, Ulrich Maurer, Peter Czabotar, Christoph Borner
      Journal of Biological Chemistry 2012 287 12
    • Mfn2 Affects Embryo Development via Mitochondrial Dysfunction and Apoptosis
      Na Zhao, Yong Zhang, Qun Liu, Wenpei Xiang, Baohong Zhang
      PLOS ONE 2015 10 5
    • Molecular dynamics simulation and automated docking of the pro-apoptotic bax protein and its complex with a peptide designed from the Bax-binding domain of anti-apoptotic Ku70
      Fabrizio Mancinelli, Michele Caraglia, Alfredo Budillon, Alberto Abbruzzese, Ettore Bismuto
      Journal of Cellular Biochemistry 2006 99 1
    • Non-substituted N-heteroaromatic selenosemicarbazone metal complexes induce apoptosis in cancer cells via activation of mitochondrial pathway
      Tatjana Srdić-Rajić, Manja Zec, Tamara Todorović, Katarina Anđelković, Siniša Radulović
      European Journal of Medicinal Chemistry 2011 46 9
    • The C-Terminal Transmembrane Domain of Bcl-xL Mediates Changes in Mitochondrial Morphology
      Jing-Yi Zheng, Yien-Che Tsai, Pradeep Kadimcherla, Rong Zhang, Julia Shi, George A. Oyler, Nada N. Boustany
      Biophysical Journal 2008 94 1
    • The Effect of Human bcl-2 and bcl-X Genes on Dengue Virus-Induced Apoptosis in Cultured Cells
      Hong-Lin Su, Yi-Ling Lin, Han-Pang Yu, Chang-Huei Tsao, Li-Kuang Chen, Yu-Tien Liu, Ching-Len Liao
      Virology 2001 282 1
    • UV irradiation inhibits ABC transporters via generation of ADP-ribose by concerted action of poly(ADP-ribose) polymerase-1 and glycohydrolase
      I E Dumitriu, R E Voll, W Kolowos, U S Gaipl, P Heyder, J R Kalden, M Herrmann
      Cell Death & Differentiation 2004 11 3
    • Vaccinia Virus F1L Interacts with Bak Using Highly Divergent Bcl-2 Homology Domains and Replaces the Function of Mcl-1
      Stephanie Campbell, Bart Hazes, Marc Kvansakul, Peter Colman, Michele Barry
      Journal of Biological Chemistry 2010 285 7
    • A Caspase-Independent Cell Clearance Program: The LEI/L-DNase II Pathway
      ALICIA TORRIGLIA, PAOLO PERANI, JEAN YVES BROSSAS, SÉVERINE ALTAIRAC, SAMIA ZEGGAI, ELISABETH MARTIN, JACQUES TRÉTON, YVES COURTOIS, MARIE-FRANCE COUNIS
      Annals of the New York Academy of Sciences 2006 926 1
    • A Soluble Form of the Pilus Protein FimA Targets the VDAC-Hexokinase Complex at Mitochondria to Suppress Host Cell Apoptosis
      Sunil K. Sukumaran, Nai Yang Fu, Chua Boon Tin, Kah Fei Wan, San San Lee, Victor C. Yu
      Molecular Cell 2010 37 6
    • Cloning and characterization of zfBLP1, a Bcl-XL homologue from the zebrafish, Danio rerio
      Ming-Chyuan Chen, Hong-Yi Gong, Ching-Yi Cheng, Jia-Pey Wang, Jiann-Ruey Hong, Jen-Leih Wu
      Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 2001 1519 1-2
    • Epoxyeicosatrienoic Acids Prevent Cisplatin-Induced Renal Apoptosis through a p38 Mitogen-Activated Protein Kinase–Regulated Mitochondrial Pathway
      Yingmei Liu, Xiaodan Lu, Sinh Nguyen, Jean L. Olson, Heather K. Webb, Deanna L. Kroetz
      Molecular Pharmacology 2013 84 6
    • GATA-3 transduces survival signals in osteoblasts through upregulation of bcl-xL gene expression
      Ruei-Ming Chen, Yi-Ling Lin, Chih-Wei Chou
      Journal of Bone and Mineral Research 2010 25 10
    • Genome-Wide Gene Expression Analysis Suggests an Important Role of Suppressed Immunity in Pathogenesis of Kashin-Beck Disease
      Shuang Wang, Xiong Guo, Xiao-ming Wu, Mikko J. Lammi, Ying Xu
      PLoS ONE 2012 7 1
    • Involvement of the Bcl-2 Family Members inPinus massonianaBark Extract induced Apoptosis in HeLa Cells
      Hongling Ma, Fei Lai, Heng Xie, Jinfa Wang, Hongbin Wang
      Phytotherapy Research 2008 22 11
    • Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes
      Konrad Kleszczyński, Stefan Tukaj, Nathalie Kruse, Detlef Zillikens, Tobias W. Fischer
      Journal of Pineal Research 2013 54 1
    • Phenobarbital promotes liver growth in c-myc/TGF-α transgenic mice by inducing hypertrophy and inhibiting apoptosis
      Sean Sanders, Snorri S. Thorgeirsson
      Carcinogenesis 1999 20 1
    • Prognostic Impact of Bcl-2 Depends on Tumor Histology and Expression of MALAT-1 lncRNA in Non–Small-Cell Lung Cancer
      Lars Henning Schmidt, Dennis Görlich, Tilmann Spieker, Christian Rohde, Martin Schuler, Michael Mohr, Julia Humberg, Tim Sauer, Nils H. Thoenissen, Andreas Huge, Reinhard Voss, Alessandro Marra, Andreas Faldum, Carsten Müller-Tidow, Wolfgang E. Berdel, Rainer Wiewrodt
      Journal of Thoracic Oncology 2014 9 9
    • Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1α or JNK signaling
      Kinnosuke Yahiro, Naoko Morinaga, Joel Moss, Masatoshi Noda
      Microbial Pathogenesis 2010 49 4
    • Sustained Phosphorylation of Bid Is a Marker for Resistance to Fas-Induced Apoptosis During Chronic Liver Diseases
      Arndt Vogel, Joseph E. Aslan, Holger Willenbring, Christian Klein, Milton Finegold, Howard Mount, Gary Thomas, Markus Grompe
      Gastroenterology 2006 130 1
    • The immunohistochemical localization of Bax and Bcl-2 and their relation to apoptosis during amelogenesis in developing rat molars
      S. Kondo, Y. Tamura, J.W. Bawden, S. Tanase
      Archives of Oral Biology 2001 46 6
    • A Novel Anticancer Agent, 8-Methoxypyrimido[4′,5′:4,5]thieno(2,3-b) Quinoline-4(3H)-One Induces Neuro 2a Neuroblastoma Cell Death through p53-Dependent, Caspase-Dependent and -Independent Apoptotic Pathways
      Upasana Sahu, Himakshi Sidhar, Pankaj S. Ghate, Gopal M. Advirao, Sathees C. Raghavan, Ranjit K. Giri, Hari Koul
      PLoS ONE 2013 8 6
    • Analysis of BAX expression in human tissues using the Anti-BAX, 4F11 monoclonal antibody on paraffin sections
      Frédérique Penault-Llorca, Reda Bouabdallan, Elisabeth Devilard, Marie-Clotilde Charton-Bain, Jacques Hassoun, Françoise Birg, Luc Xerri
      Pathology - Research and Practice 1998 194 7
    • Control of mitochondrial physiology and cell death by the Bcl-2 family proteins Bax and Bok
      Beatrice D'Orsi, Julia Mateyka, Jochen H.M. Prehn
      Neurochemistry International 2017 109
    • Interaction of the full-length Bax protein with biomimetic mitochondrial liposomes: A small-angle neutron scattering and fluorescence study
      Dmitri Satsoura, Norbert Kučerka, Sanjeevan Shivakumar, Jeremy Pencer, Corrie Griffiths, Brian Leber, David W. Andrews, John Katsaras, Cécile Fradin
      Biochimica et Biophysica Acta (BBA) - Biomembranes 2012 1818 3
    • Mycoplasma synoviae induces upregulation of apoptotic genes, secretion of nitric oxide and appearance of an apoptotic phenotype in infected chicken chondrocytes
      Daliborka Dusanic, Dusan Bencina, Irena Oven, Ivanka Cizelj, Mojca Bencina, Mojca Narat
      Veterinary Research 2012 43 1
    • Oxidative Stress and Mitogen-Activated Protein Kinase Pathways Involved in Cadmium-Induced BRL 3A Cell Apoptosis
      Zhang Yiran, Jiang Chenyang, Wang Jiajing, Yuan Yan, Gu Jianhong, Bian Jianchun, Liu Xuezhong, Liu Zongping
      Oxidative Medicine and Cellular Longevity 2013 2013
    • Suppression of human ovarian SKOV-3 cancer cell growth by Duchesnea phenolic fraction is associated with cell cycle arrest and apoptosis
      Bo Peng, Qi Chang, Liwei Wang, Qin Hu, Yuqi Wang, Jintian Tang, Xinmin Liu
      Gynecologic Oncology 2008 108 1
    • A novel checkpoint in the Bcl-2–regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells
      Christopher E. Andoniou, Daniel M. Andrews, Mitali Manzur, Paola Ricciardi-Castagnoli, Mariapia A. Degli-Esposti
      The Journal of Cell Biology 2004 166 6
    • Binding mitochondria to cryogel monoliths allows detection of proteins specifically released following permeability transition
      M. Teilum, M.J. Hansson, M.B. Dainiak, R. Månsson, S. Surve, E. Elmér, P. Önnerfjord, G. Mattiasson
      Analytical Biochemistry 2006 348 2
    • Mutation-induced protein interaction kinetics changes affect apoptotic network dynamic properties and facilitate oncogenesis
      Linjie Zhao, Tanlin Sun, Jianfeng Pei, Qi Ouyang
      Proceedings of the National Academy of Sciences 2015 112 30
    • Progesterone-action in the decidual mesometrium of pregnancy☆ ☆This work was supported by NIH Grant HD 38724.
      Thomas F. Ogle
      Steroids 2002 67 1
    • Purification and Biochemical Properties of Soluble Recombinant Human Bax
      Shareta Lewis, Susanne S. Bethell, Sahil Patel, Jean-Claude Martinou, Bruno Antonsson
      Protein Expression and Purification 1998 13 1
    • Receptor-mediated uptake of an extracellular Bcl-xL fusion protein inhibits apoptosis
      X.-H. Liu, J. C. Castelli, R. J. Youle
      Proceedings of the National Academy of Sciences 1999 96 17
    • Resveratrol Preserves Mitochondrial Function, Stimulates Mitochondrial Biogenesis, and Attenuates Oxidative Stress in Regulatory T Cells of Mice Fed a High-Fat Diet
      Bin Wang, Jin Sun, Yuhua Ma, Guirong Wu, Yingjie Tian, Yonghui Shi, Guowei Le
      Journal of Food Science 2014 79 9
    • Scission, spores, and apoptosis: a proposal for the evolutionary origin of mitochondria in cell death induction
      Stephan Frank, Everett G Robert, Richard J Youle
      Biochemical and Biophysical Research Communications 2003 304 3
    • Targeting Bax interaction sites reveals that only homo-oligomerization sites are essential for its activation
      R Peng, J-S Tong, H Li, B Yue, F Zou, J Yu, L Zhang
      Cell Death & Differentiation 2013 20 5
    • Urocortin-2 suppression of p38-MAPK signaling as an additional mechanism for ischemic cardioprotection
      Xiu-Fang Gao, Yue Zhou, Da-Ying Wang, Kar-Sheng Lew, Arthur Mark Richards, Peipei Wang
      Molecular and Cellular Biochemistry 2015 398 1-2
    • Abnormal Intracellular Localization of Bax with a Normal Membrane Anchor Domain in Human Lung Cancer Cell Lines
      Alaa-eldin Salah-eldin, Shoichi Inoue, Masumi Tsuda, Akihiro Matsuura
      Japanese Journal of Cancer Research 2000 91 12
    • BILE SALT TAUROURSODEOXYCHOLIC ACID MODULATION OF BAX TRANSLOCATION TO MITOCHONDRIA PROTECTS THE LIVER FROM WARM ISCHEMIA-REPERFUSION INJURY IN THE RAT1
      Fumitaka Ishigami, Shigeyuki Naka, Kazuyoshi Takeshita, Yoshimasa Kurumi, Kazuyoshi Hanasawa, Tohru Tani
      Transplantation 2001 72 11
    • Biophysical Characterization of the Oligomeric State of Bax and Its Complex Formation with Bcl-XL
      Yee-Joo Tan, Walter Beerheide, Anthony E. Ting
      Biochemical and Biophysical Research Communications 1999 255 2
    • Comparison of Membrane Insertion Pathways of the Apoptotic Regulator Bcl-xL and the Diphtheria Toxin Translocation Domain
      Mauricio Vargas-Uribe, Mykola V. Rodnin, Alexey S. Ladokhin
      Biochemistry 2013 52 45
    • Deletion of the BH1 Domain of Bcl-2 Accelerates Apoptosis by Acting in a Dominant Negative Fashion
      Makoto Kawatani, Masaya Imoto
      Journal of Biological Chemistry 2003 278 22
    • High Bcr-Abl expression prevents the translocation of Bax and Bad to the mitochondrion
      K Keeshan, TG Cotter, SL McKenna
      Leukemia 2002 16 9
    • Preconditioning prevents loss in mitochondrial function and release of cytochrome c during prolonged cardiac ischemia/reperfusion
      Kathleen C. Lundberg, Luke I. Szweda
      Archives of Biochemistry and Biophysics 2006 453 1
    • Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine
      Shaoping Wu, Lijuan Yuan, Yongguo Zhang, Fangning Liu, Guohua Li, Ke Wen, Jacob Kocher, Xingdong Yang, Jun Sun
      Gut Pathogens 2013 5 1
    • The Association of Aiolos Transcription Factor and Bcl-xL Is Involved in the Control of Apoptosis
      Angelita Rebollo, Verónica Ayllón, Aarne Fleischer, Carlos Martínez-A., Angel Zaballos
      The Journal of Immunology 2001 167 11
    • The matrix (M) protein of newcastle disease virus binds to human bax through its BH3 domain
      Aidin Molouki, Yi-Te Hsu, Fatemeh Jahanshiri, Syahril Abdullah, Rozita Rosli, Khatijah Yusoff
      Virology Journal 2011 8 1
    • Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates established human hepatoma in vivo
      J Zhao, J Jin, X Zhang, M Shi, J Dai, M Wu, R Wang, Y Guo
      Cancer Gene Therapy 2006 13 4
    • Anticancer Activity of S-Allylmercapto-L-cysteine on Implanted Tumor of Human Gastric Cancer Cell
      Yongkyu Lee, Hejin Kim, Jinhwa Lee, Kyongtai Kim
      Biological & Pharmaceutical Bulletin 2011 34 5
    • Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors
      Yu Yang, Zeyu Xiong, Sheng Zhang, Yan Yan, Justin Nguyen, Bernard Ng, Huifang Lu, John Brendese, Fan Yang, Hong Wang, Xiao-Feng Yang
      Biochemical Journal 2005 392 1
    • Phosphorylation of the Tumor Necrosis Factor Receptor CD120a (p55) Recruits Bcl-2 and Protects against Apoptosis
      Vincent Cottin, Annemie A. Van Linden, David W. H. Riches
      Journal of Biological Chemistry 2001 276 20
    • Potent Antitumor Efficacy of ST13 for Colorectal Cancer Mediated by Oncolytic Adenovirus via Mitochondrial Apoptotic Cell Death
      Min Yang, Xin Cao, Ming Can Yu, Jin Fa Gu, Zong Hou Shen, Miao Ding, De Bing Yu, Shu Zheng, Xin Yuan Liu
      Human Gene Therapy 2008 19 4
    • Ran suppresses paclitaxel-induced apoptosis in human glioblastoma cells
      Im Sun Woo, Han-Su Jang, So Young Eun, Hyo Jung Kim, Sun Ah Ham, Hye Jung Kim, Jae Heun Lee, Ki Churl Chang, Jin-Hoi Kim, Chang Woo Han, Han Geuk Seo
      Apoptosis 2008 13 10
    • Subcellular Localization and Dynamics of the Bcl-2 Family of Proteins
      Nikolay Popgeorgiev, Lea Jabbour, Germain Gillet
      Frontiers in Cell and Developmental Biology 2018 6
    • Taurine Monochloramine Activates a Cell Death Pathway InvolvingBaxand Caspase-9
      Derek K. Emerson, Michael L. McCormick, Jennifer A. Schmidt, C. Michael Knudson
      Journal of Biological Chemistry 2005 280 5
    • The Bcl-2 Family in Host-Virus Interactions
      Marc Kvansakul, Sofia Caria, Mark Hinds
      Viruses 2017 9 10
    • The role of the innate immune recognition system in the pathogenesis of primary biliary cirrhosis: a conceptual view
      Peter A. Berg
      Liver International 2011 31 7
    • Apoptosis in primary lymphoid organs with aging
      Rosa M. Sainz, Juan C. Mayo, R.J. Reiter, D.X. Tan, C. Rodriguez
      Microscopy Research and Technique 2003 62 6
    • BAX and Tumor Suppressor TRP53 Are Important in Regulating Mutagenesis in Spermatogenic Cells in Mice1
      Guogang Xu, Kristine S. Vogel, C. Alex McMahan, Damon C. Herbert, Christi A. Walter
      Biology of Reproduction 2010 83 6
    • Bax and B-cell-lymphoma 2 mediate proapoptotic signaling following chronic isolation stress in rat brain
      J. ZLATKOVIĆ, D. FILIPOVIĆ
      Neuroscience 2012 223
    • Complete activation of Bax by a single site mutation
      H Zhou, Q Hou, J L Hansen, Y-T Hsu
      Oncogene 2007 26 50
    • Cytotoxic Activity from Curcuma zedoaria Through Mitochondrial Activation on Ovarian Cancer Cells
      Yujin Shin, Yongkyu Lee
      Toxicological Research 2013 29 4
    • Dilinoleoylphosphatidylcholine Reproduces the Antiapoptotic Actions of Polyenylphosphatidylcholine Against Ethanol-Induced Hepatocyte Apoptosis
      Ki M. Mak, Kefeng Wen, Chaoling Ren, Charles S. Lieber
      Alcoholism: Clinical and Experimental Research 2003 27 6
    • Dilinoleoylphosphatidylcholine Reproduces the Antiapoptotic Actions of Polyenylphosphatidylcholine Against Ethanol-Induced Hepatocyte Apoptosis
      Ki M. Mak, Kefeng Wen, Chaoling Ren, Charles S. Lieber
      Alcoholism: Clinical and Experimental Research 2003 27 6
    • Induction of bax protein and degradation of lamin A during p53-dependent apoptosis induced by chemotherapeutic agents in human cancer cell lines
      Yuan–Soon Ho, Horng–Mo Lee, Chuang–Rung Chang, Jen–Kun Lin
      Biochemical Pharmacology 1999 57 2
    • Mono- or Double-Site Phosphorylation Distinctly Regulates the Proapoptotic Function of Bax
      Qinhong Wang, Shi-Yong Sun, Fadlo Khuri, Walter J. Curran, Xingming Deng, Bill Hooker
      PLoS ONE 2010 5 10
    • N-Benzoyl-12-nitrodehydroabietylamine-7-one, a novel dehydroabietylamine derivative, induces apoptosis and inhibits proliferation in HepG2 cells
      Ling-Ying Lin, Yong-Li Bao, Yong Chen, Lu-Guo Sun, Xiao-Guang Yang, Biao Liu, Zhong-Xiang Lin, Yu-Wei Zhang, Chun-Lei Yu, Yin Wu, Yu-Xin Li
      Chemico-Biological Interactions 2012 199 2
    • Oxidative Stress Induced by MnSOD-p53 Interaction: Pro- or Anti-Tumorigenic?
      Delira Robbins, Yunfeng Zhao
      Journal of Signal Transduction 2012 2012
    • The BH3 domain is required for caspase-independent cell death induced by Bax and oligomycin
      M E Fitch, C-M Chang, T G Parslow
      Cell Death & Differentiation 2000 7 4
    • Therapeutic Modulation of Apoptosis: Targeting the BCL-2 Family at the Interface of the Mitochondrial Membrane
      Kathleen N. Nemec, Annette R. Khaled
      Yonsei Medical Journal 2008 49 5
    • Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis
      JINYAN ZHAO, XUZHENG CHEN, WEI LIN, GUANGWEN WU, QUNCHUAN ZHUANG, XIAOYONG ZHONG, ZHENFENG HONG, JUN PENG
      International Journal of Oncology 2013 42 3
    • Block of a Mitochondrial-Mediated Apoptotic Pathway in Tax-Expressing Murine Fibroblasts
      Daniela Saggioro, Silvia Barp, Luigi Chieco-Bianchi
      Experimental Cell Research 2001 269 2
    • Mitochondria are involved in the neurogenic neuroprotection conferred by stimulation of cerebellar fastigial nucleus
      Ping Zhou, Liping Qian, Theresa Zhou, Costantino Iadecola
      Journal of Neurochemistry 2005 95 1
    • Nitric Oxide, Part G Oxidative and Nitrosative Stress in Redox Regulation of Cell Signaling
      Orazio Cantoni, Ilaria Tommasini, Liana Cerioni
      2008 441
    • Preapoptotic cell stress response of primary hepatocytes
      Damijan Nipič, Aleš Pirc, Blaž Banič, Dušan Šuput, Irina Milisav
      Hepatology 2010 51 6
    • Thermodynamic Measurements of Bilayer Insertion of a Single Transmembrane Helix Chaperoned by Fluorinated Surfactants
      Alexander Kyrychenko, Mykola V. Rodnin, Yevgen O. Posokhov, Andrea Holt, Bernard Pucci, J. Antoinette Killian, Alexey S. Ladokhin
      Journal of Molecular Biology 2012 416 3
    • Type I Interferon Gene Transfer Sensitizes Melanoma Cells to Apoptosis via a Target Activity on Mitochondrial Function
      Paola Matarrese, Luigi Di Biase, Laura Santodonato, Elisabetta Straface, Monica Mecchia, Barbara Ascione, Giorgio Parmiani, Filippo Belardelli, Maria Ferrantini, Walter Malorni
      The American Journal of Pathology 2002 160 4
    • mTORC2 Phosphorylation of Akt1: A Possible Mechanism for Hydrogen Sulfide-Induced Cardioprotection
      Yue Zhou, Daying Wang, Xiufang Gao, Karsheng Lew, Arthur Mark Richards, Peipei Wang, Anindita Das
      PLoS ONE 2014 9 6
    • A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy
      Ajay K. Chaudhary, Neelu Yadav, Tariq A. Bhat, Jordan O’Malley, Sandeep Kumar, Dhyan Chandra
      Drug Discovery Today 2016 21 1
    • BimL involvement in Bax activation during UV irradiation-induced apoptosis
      Miaojuan Chen, Da Xing, Tongsheng Chen, Lan Zhang
      Biochemical and Biophysical Research Communications 2007 358 2
    • Caspase-independent apoptosis in Friend’s erythroleukemia cells: role of mitochondrial ATP synthesis impairment in relocation of apoptosis-inducing factor and endonuclease G
      Marina Comelli, Nadia Genero, Irene Mavelli
      Journal of Bioenergetics and Biomembranes 2009 41 1
    • Characterisation of the Bax-nucleophosmin interaction: the importance of the Bax C-terminus
      Jane Thompson, Keith Finlayson, Eliane Salvo-Chirnside, David MacDonald, James McCulloch, Lorraine Kerr, John Sharkey
      Apoptosis 2008 13 3
    • Dexamethasone decreases cholestatic liver injury via inhibition of intrinsic pathway with simultaneous enhancement of mitochondrial biogenesis
      Mao-Meng Tiao, Tsu-Kung Lin, Jin-Bor Chen, Cha-Wei Liou, Pei-Wen Wang, Chao-Chen Huang, Yao-Min Chou, Ying-Hsien Huang, Jiin-Haur Chuang
      Steroids 2011 76 7
    • Escape from Apoptosis after Prolonged Serum Deprivation Is Associated with the Regulation of the Mitochondrial Death Pathway by Bcl-
      Xiao-Ju Zhang, Jun Yan, Leila Cuttle, Zoltan Endre, Glenda Gobé
      Biochemical and Biophysical Research Communications 2000 277 2
    • Exposure to the Neurotoxic Dinoflagellate, Alexandrium catenella, Induces Apoptosis of the Hemocytes of the Oyster, Crassostrea gigas
      Walid Medhioub, Simon Ramondenc, Audrey Vanhove, Agnes Vergnes, Estelle Masseret, Veronique Savar, Zouher Amzil, Mohamed Laabir, Jean Rolland
      Marine Drugs 2013 11 12
    • Peroxynitrite-induced mitochondrial translocation of PKCα causes U937 cell survival
      Liana Cerioni, Letizia Palomba, Bernhard Brüne, Orazio Cantoni
      Biochemical and Biophysical Research Communications 2006 339 1
    • Re-evaluation of the distinction between type I and type II cells: The necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon fas receptor activation
      Marco Tafani, Natalie O. Karpinich, Ada Serroni, Matteo A. Russo, John L. Farber
      Journal of Cellular Physiology 2006 208 3
    • Sex Differences in Cancer: Epidemiology, Genetics and Therapy
      Hae-In Kim, Hyesol Lim, Aree Moon
      Biomolecules & Therapeutics 2018 26 4
    • Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport
      Sreekanth Rajan, Minjoo Choi, Quoc Toan Nguyen, Hong Ye, Wei Liu, Hui Ting Toh, CongBao Kang, Neelagandan Kamariah, Chi Li, Huiya Huang, Carl White, Kwanghee Baek, Gerhard Grüber, Ho Sup Yoon
      Scientific Reports 2015 5 1
    • Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site
      Onyinyechukwu Uchime, Zhou Dai, Nikolaos Biris, David Lee, Sachdev S. Sidhu, Sheng Li, Jonathan R. Lai, Evripidis Gavathiotis
      Journal of Biological Chemistry 2016 291 1
    • Viral pro-survival proteins block separate stages in Bax activation but changes in mitochondrial ultrastructure still occur
      J R Cross, A Postigo, K Blight, J Downward
      Cell Death & Differentiation 2008 15 6
    • Altered expression of calcium- and apoptosis-regulating proteins in multiple system atrophy purkinje cells
      U. W�llner, M. Weller, J. Kornhuber, A. Bornemann, J. B. Schulz, P. Riederer, T. Klockgether
      Movement Disorders 2000 15 2
    • Apamin inhibits THP-1-derived macrophage apoptosis via mitochondria-related apoptotic pathway
      Soo-Jung Kim, Ji-Hyun Park, Kyung-Hyun Kim, Woo-Ram Lee, Hyun-Jin An, Bo-Kyung Min, Sang-Mi Han, Kee-Sik Kim, Kwan-Kyu Park
      Experimental and Molecular Pathology 2012 93 1
    • Apoptosis regulating proteins as targets of therapy for haematological malignancies
      Steven M Kornblau, Marina Konopleva, Michael Andreeff
      Expert Opinion on Investigational Drugs 1999 8 12
    • Detailing the role of Bax translocation, cytochromecrelease, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF
      Bruna Pucci, Francesca Bertani, Natalie O. Karpinich, Manuela Indelicato, Matteo A. Russo, John L. Farber, Marco Tafani
      Journal of Cellular Physiology 2008 217 2
    • Imexon activates an intrinsic apoptosis pathway in RPMI8226 myeloma cells
      Katerina Dvorakova, Claire M Payne, Terry H Landowski, Margaret E Tome, Daniel S Halperin, Robert T Dorr
      Anti-Cancer Drugs 2002 13 10
    • Intrinsic apoptosis and proinflammatory cytokines regulated in human astrocytes infected with enterovirus 71
      Zheng Xing, Carol J. Cardona, Yu Jin, Zerui Zhang, Renmen Zhou, Chunyang Wang
      Journal of General Virology 2015 96 10
    • Involvement of Bax Redistribution in the Induction of Germ Cell Apoptosis in Neonatal Mouse Testes
      Elia Damavandi, Yoshitaka Hishikawa, Shin-ichi Izumi, Masashi Shin, Takehiko Koji
      ACTA HISTOCHEMICA ET CYTOCHEMICA 2002 35 6
    • Modification of glucocorticoid sensitivity by MAP kinase signaling pathways in glucocorticoid-induced T-cell apoptosis
      Tomoko Tanaka, Taijiro Okabe, Shigeki Gondo, Mitsue Fukuda, Masahiro Yamamoto, Tsukuru Umemura, Kenzaburo Tani, Masatoshi Nomura, Kiminobu Goto, Toshihiko Yanase, Hajime Nawata
      Experimental Hematology 2006 34 11
    • Oxidative stress-induced apoptotic insults to rat osteoblasts are attenuated by nitric oxide pretreatment via GATA-5-involved regulation of Bcl-X L gene expression and protein translocation
      Gong-Jhe Wu, Weu Wang, Yi-Ling Lin, Shing Hwa Liu, Ruei-Ming Chen
      Archives of Toxicology 2016 90 4
    • Radiation-induced apoptosis in human myeloma cell line increases BCL-2/BAX dimer formation and does not result in BAX/BAX homodimerization
      Igor V. Filippovich, Natalya I. Sorokina, Albert Lisbona, Michel Ch�rel, Jean-Fran�ois Chatal
      International Journal of Cancer 2001 92 5
    • The Cytosolic Domain of Fis1 Binds and Reversibly Clusters Lipid Vesicles
      Robert C. Wells, R. Blake Hill, Petri Kursula
      PLoS ONE 2011 6 6
    • Utilizing mitochondrial events as biomarkers for imaging apoptosis
      N Yivgi-Ohana, M Eifer, Y Addadi, M Neeman, A Gross
      Cell Death & Disease 2011 2 6
    • Acid destabilization of the solution conformation of Bcl-XLdoes not drive its pH-dependent insertion into membranes
      Guruvasuthevan R. Thuduppathy, R. Blake Hill
      Protein Science 2006 15 2
    • Anthraquinone G503 Induces Apoptosis in Gastric Cancer Cells through the Mitochondrial Pathway
      Lijun Huang, Ting Zhang, Shuai Li, Junting Duan, Fang Ye, Hanxiang Li, Zhigang She, Guoquan Gao, Xia Yang, Javier S. Castresana
      PLoS ONE 2014 9 9
    • Ciprofloxacin as a potential radio-sensitizer to tumor cells and a radio-protectant for normal cells: differential effects on γ-H2AX formation, p53 phosphorylation, Bcl-2 production, and cell death
      Juliann G. Kiang, Bradley R. Garrison, Joan T. Smith, Risaku Fukumoto
      Molecular and Cellular Biochemistry 2014 393 1-2
    • Differentially expressed pro- and anti-apoptogenic genes in response to benzene exposure: Immunohistochemical localization of p53, Bag, Bad, Bax, Bcl-2, and Bcl-w in lung epithelia
      Cyprian V. Weaver, Shi-Ping Liu
      Experimental and Toxicologic Pathology 2008 59 5
    • Increased oxidative-modifications of cytosolic proteins in 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-exposed rat liver
      Vijay V. Upreti, Kwan-Hoon Moon, Li-Rong Yu, Insong J. Lee, Natalie D. Eddington, Xiaoying Ye, Timothy D. Veenstra, Byoung-Joon Song
      PROTEOMICS 2011 11 2
    • Low dose of methylmercury (MeHg) exposure induces caspase mediated-apoptosis in cultured neural progenitor cells
      Jun Watanabe, Tomoya Nakamachi, Hirokazu Ohtaki, Akira Naganuma, Seiji Shioda, Shigeo Nakajo
      The Journal of Toxicological Sciences 2013 38 6
    • Myocardial apoptosis after cardioplegic arrest in the neonatal lamb
      James M Hammel, Christopher A Caldarone, Timothy L Van Natta, Li Xing Wang, Karl F Welke, Weigen Li, Scott Niles, Elisa Barner, Thomas D Scholz, Douglas M Behrendt, Jeffrey L Segar
      The Journal of Thoracic and Cardiovascular Surgery 2003 125 6
    • Nitrosative stress induces osteoblast apoptosis through downregulating MAPK-mediated NFκB/AP-1 activation and subsequent Bcl-XL expression
      Ta-Liang Chen, Gong-Jhe Wu, Chun-Sen Hsu, Tsorng-Harn Fong, Ruei-Ming Chen
      Chemico-Biological Interactions 2010 184 3
    • Nucleocytoplasmic shuttling of BID is involved in regulating its activities in the DNA-damage response
      G Oberkovitz, L Regev, A Gross
      Cell Death & Differentiation 2007 14 9
    • Overexpression of bax induces down-regulation of store-operated calcium entry in prostate cancer cells
      Na Li, Lin Zheng, Peihui Lin, David Danielpour, Zui Pan, Jianjie Ma
      Journal of Cellular Physiology 2008 216 1
    • Oxysophoridine Protects Against Focal Cerebral Ischemic Injury by Inhibiting Oxidative Stress and Apoptosis in Mice
      Teng-Fei Wang, Zhen Lei, Yu-Xiang Li, Yong-Sheng Wang, Jie Wang, Shu-Jing Wang, Yin-Ju Hao, Ru Zhou, Shao-Ju Jin, Juan Du, Juan Li, Tao Sun, Jian-Qiang Yu
      Neurochemical Research 2013 38 11
    • Polyamine depletion switches the form of 2-deoxy-d-ribose-induced cell death from apoptosis to necrosis in HL-60 cells
      Maria Giuseppina Monti, Stefania Ghiaroni, Gaetano Marverti, Monica Montanari, Maria Stella Moruzzi
      The International Journal of Biochemistry & Cell Biology 2004 36 7
    • Qianliening capsule treats benign prostatic hyperplasia via induction of prostatic cell apoptosis
      HAIYIN ZHENG, WEI XU, JIUMAO LIN, JUN PENG, ZHENFENG HONG
      Molecular Medicine Reports 2013 7 3
    • RACK1 promotes Bax oligomerization and dissociates the interaction of Bax and Bcl-XL
      Yinyuan Wu, Yinyin Wang, Yang Sun, Liying Zhang, Dianjun Wang, Fangli Ren, Donald Chang, Zhijie Chang, Baoqing Jia
      Cellular Signalling 2010 22 10
    • p38 MAP kinase and ERK play an important role in nitric oxide-induced apoptosis of the mouse embryonic stem cells
      Jin-Ha Lee, Sang-Won Lee, Seong-Ho Choi, Sun-Hun Kim, Won-Jae Kim, Ji-Yeon Jung
      Toxicology in Vitro 2013 27 1
    • Autophagosome and Phagosome
      Iwona A. Ciechomska, Christoph G. Goemans, Aviva M. Tolkovsky
      2008 445
    • BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death
      Han K. Ho, Zhong-Hua Hu, Shie-Pon Tzung, David M. Hockenbery, Nelson Fausto, Sidney D. Nelson, Sam A. Bruschi
      Biochemical Pharmacology 2005 69 1
    • ChBax/Bak as key regulators of the mitochondrial apoptotic pathway: Cloned and characterized in Crassostrea hongkongensis
      Zhiming Xiang, Fufa Qu, Fuxuan Wang, Shu Xiao, Li Jun, Yang Zhang, Ziniu Yu
      Fish & Shellfish Immunology 2015 42 2
    • Charge Profile Analysis Reveals That Activation of Pro-apoptotic Regulators Bax and Bak Relies on Charge Transfer Mediated Allosteric Regulation
      Crina-Maria Ionescu, Radka Svobodová Vařeková, Jochen H. M. Prehn, Heinrich J. Huber, Jaroslav Koča, James M. Briggs
      PLoS Computational Biology 2012 8 6
    • Cytosolic Hsp60 Can Modulate Proteasome Activity in Yeast
      Bella Kalderon, Gleb Kogan, Ettel Bubis, Ophry Pines
      Journal of Biological Chemistry 2015 290 6
    • Dying to protect: cell death and the control of T-cell homeostasis
      Kun-Po Li, Sharmila Shanmuganad, Kaitlin Carroll, Jonathan D. Katz, Michael B. Jordan, David A. Hildeman
      Immunological Reviews 2017 277 1
    • Endoplasmic Reticulum Calcium Release Engages Bax Translocation in Cortical Astrocytes
      A. P. Morales, A. C. P. Carvalho, P. T. Monteforte, H. Hirata, S. W. Han, Y. -T. Hsu, S. S. Smaili
      Neurochemical Research 2011 36 5
    • Evaluation of bax and bcl-2 expression in odontogenic keratocysts and orthokeratinized odontogenic cysts: A comparison of two cysts
      A. Rangiani, P. Motahhary
      Oral Oncology 2009 45 7
    • Evidence for microRNA-31 dependent Bim-Bax interaction preceding mitochondrial Bax translocation during radiation-induced apoptosis
      Ashish Kumar, Soma Ghosh, Sudhir Chandna
      Scientific Reports 2015 5 1
    • Identification of Bax-voltage-dependent anion channel 1 complexes in digitonin-solubilized cerebellar granule neurons
      Dennis B. Huckabee, Mika B. Jekabsons
      Journal of Neurochemistry 2011 119 5
    • Improvement of Heart Redox States Contributes to the Beneficial Effects of Selenium Against Penconazole-Induced Cardiotoxicity in Adult Rats
      Mariem Chaâbane, Meriem Tir, Safa Hamdi, Ons Boudawara, Kamel Jamoussi, Tahia Boudawara, Raoudha Ellouze Ghorbel, Najiba Zeghal, Nejla Soudani
      Biological Trace Element Research 2016 169 2
    • Interaction of pro-apoptotic protein HGTD-P with heat shock protein 90 is required for induction of mitochondrial apoptotic cascades
      Jee-Youn Kim, Su-Mi Kim, Jeong-Hun Ko, Ji-Hye Yim, Jin-Hae Park, Jae-Hoon Park
      FEBS Letters 2006 580 13
    • Knockdown of RCAN1.4 Increases Susceptibility to FAS-mediated and DNA-damage-induced Apoptosis by Upregulation of p53 Expression
      Young Sun Kim, Hong Joon Lee, Chorong Jang, Ho-Shik Kim, Young-Jin Cho
      The Korean Journal of Physiology and Pharmacology 2009 13 6
    • Molecular cloning, characterization and expression analysis of (B-cell lymphoma-2 associated X protein) Bax in the orange-spotted grouper (Epinephelus coioides) after the Vibrio alginolyticus challenge
      Sheng-Wei Luo, Wei-Na Wang, Zuo-Ming Sun, Fu-Xing Xie, Jing-Rong Kong, Yuan Liu, Chang-Hong Cheng
      Developmental & Comparative Immunology 2016 60
    • Regulation of Apoptotic Effects by Erythrocarpine E, a Cytotoxic Limonoid from Chisocheton erythrocarpus in HSC-4 Human Oral Cancer Cells
      Noor Hasima Nagoor, Norliza Shah Jehan Muttiah, Chong Soon Lim, Lionel L. A. In, Khalit Mohammad, Khalijah Awang, Paul C. Driscoll
      PLoS ONE 2011 6 8
    • Serine 392 phosphorylation modulates p53 mitochondrial translocation and transcription-independent apoptosis
      Cédric Castrogiovanni, Béranger Waterschoot, Olivier De Backer, Patrick Dumont
      Cell Death & Differentiation 2018 25 1
    • Variations in the rheostat model of apoptosis: What studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins
      Robert W. Nickells
      Experimental Eye Research 2010 91 1
    • Activation of caspases and cleavage of Bid are required for tyrosine and phenylalanine deficiency-induced apoptosis of human A375 melanoma cells
      Xiaokang Ge, Ya-Min Fu, Yi-Qi Li, Gary G Meadows
      Archives of Biochemistry and Biophysics 2002 403 1
    • Apoptosis in Human Term Placenta Is Not Increased during Labor but Can Be Massively Induced In Vitro1
      Nadia Cirelli, André Moens, Philippe Lebrun, Christiane Gueuning, Josiane Delogne-Desnoeck, Anne-Marie Vanbellinghen, Sylvain Meuris
      Biology of Reproduction 1999 61 2
    • CD44 co-stimulates apoptosis in thymic lymphomas and T cell hybridomas
      R Guy, E Yefenof, D Naor, A Dorogin, Y Zilberman
      Cellular Immunology 2002 216 1-2
    • Comparison of lipid-dependent bilayer insertion of pHLIP and its P20G variant
      Victor Vasquez-Montes, Janessa Gerhart, Kelly E. King, Damien Thévenin, Alexey S. Ladokhin
      Biochimica et Biophysica Acta (BBA) - Biomembranes 2018 1860 2
    • Dissimilar mechanisms of cytochrome c release induced by octyl glucoside-activated BAX and by BAX activated with truncated BID
      Tsyregma Li, Tatiana Brustovetsky, Bruno Antonsson, Nickolay Brustovetsky
      Biochimica et Biophysica Acta (BBA) - Bioenergetics 2010 1797 1
    • Effect of Hyperoxia on Serine Phosphorylation of Apoptotic Proteins in Mitochondrial Membranes of the Cerebral Cortex of Newborn Piglets
      Nadege A. Brutus, Sarah Hanley, Qazi M. Ashraf, Om P. Mishra, Maria Delivoria-Papadopoulos
      Neurochemical Research 2009 34 7
    • Germ cell apoptosis and expression of Bcl-2 and Bax in porcine testis under normal and heat stress conditions
      Xiaorui Fan, Huaming Xi, Zhen Zhang, Yajun Liang, Qinghong Li, Junping He
      Acta Histochemica 2017 119 3
    • JTE-522-induced apoptosis in human gastric adenocarinoma cell line AGS cells by caspase activation accompanying cytochrome C release, membrane translocation of Bax and loss of mitochondrial membrane potential
      Hong-Liang Li, Dan-Dan Chen, Xiao-Hong Li, Hai-Wei Zhang, Jun-Hua Lü, Xian-Da Ren, Cun-Chuan Wang
      World Journal of Gastroenterology 2002 8 2
    • Radiation-Induced Hyposuppression of the Hypothalamic-Pituitary-Adrenal Axis is Associated with Alterations of Hippocampal Corticosteroid Receptor Expression
      Nataša Veličković, Ana Djordjević, Gordana Matić, Anica Horvat
      Radiation Research 2008 169 4
    • Regulation of Cell Survival Mechanisms in Alzheimer's Disease by Glycogen Synthase Kinase-3
      Marjelo A. Mines, Eleonore Beurel, Richard S. Jope
      International Journal of Alzheimer's Disease 2011 2011
    • Subcellular Distribution and Redistribution of Bcl-2 Family Proteins in Human Leukemia Cells Undergoing Apoptosis
      Li Jia, Marion G. Macey, Yuzhi Yin, Adrian C. Newland, Stephen M. Kelsey
      Blood 1999 93 7
    • The Biphasic Effects of Oxidized-Low Density Lipoprotein on the Vasculogenic Function of Endothelial Progenitor Cells
      Feng-Yen Lin, Nai-Wen Tsao, Chun-Ming Shih, Yi-Wen Lin, Jong-Shiua Yeh, Jaw-Wen Chen, Hironori Nakagami, Ryuichi Morishita, Tatsuya Sawamura, Chun-Yao Huang, Maurizio Pesce
      PLOS ONE 2015 10 5
    • Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation
      Daniel Relles, Galina I. Chipitsyna, Qiaoke Gong, Charles J. Yeo, Hwyda A. Arafat
      Advances in Preventive Medicine 2016 2016
    • Transient expression of the Bcl-2 family member, A1-a, results in nuclear localization and resistance to staurosporine-induced apoptosis
      R D Somogyi, Y Wu, A Orlofsky, M B Prystowsky
      Cell Death & Differentiation 2001 8 8
    • Bax Inhibitor-1 down-regulation in the progression of chronic liver diseases
      Andromachi Kotsafti, Fabio Farinati, Romilda Cardin, Patrizia Burra, Marina Bortolami
      BMC Gastroenterology 2010 10 1
    • Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak
      J Megyesi, A Tarcsafalvi, NSHL Seng, R Hodeify, PM Price
      Cell Death Discovery 2016 2 1
    • Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis
      Chang Gong Li, Mike Gruidl, Steven Eschrich, Susan McCarthy, Hong-Gang Wang, Mark G. Alexandrow, Timothy J. Yeatman
      International Journal of Cancer 2008 123 2
    • Intracellular Redistribution of Interferon-Inducible Proteins Nmi and IFP 35 in Apoptotic Cells
      Jun Chen, Louie Naumovski
      Journal of Interferon & Cytokine Research 2002 22 2
    • PECAM-1, Apoptosis and CD34+Precursors
      Maria Zocchi, A Poggi
      Leukemia & Lymphoma 2004 45 11
    • Pro- and anti-apoptotic evidence for cholinergic denervation and hippocampal sympathetic ingrowth in rat dorsal hippocampus
      Lindy E. Harrell, Dee S. Parsons, Krystyna Kolasa
      Experimental Neurology 2005 194 1
    • Retinal Pigmented Epithelial Cells Cytotoxicity and Apoptosis through Activation of the Mitochondrial Intrinsic Pathway: Role Of Indocyanine Green, Brilliant Blue and Implications for Chromovitrectomy
      Fernando M. Penha, Marianne Pons, Elaine Fiod Costa, Nilana Meza Tenório Barros, Eduardo B. Rodrigues, Emmerson Badaró Cardoso, Eduardo Dib, Mauricio Maia, Maria E. Marin-Castaño, Michel Eid Farah, Edward Chaum
      PLoS ONE 2013 8 5
    • Ultrasonication processed Panax ginseng berry extract induces apoptosis through an intrinsic apoptosis pathway in HepG2 cells
      Hyunwoo Jung, Jinhyung Bae, Sung Kwon Ko, Uy Dong Sohn
      Archives of Pharmacal Research 2016 39 6
    • A Novel 29-kDa Crystal Protein fromBacillus thuringiensisInduces Caspase Activation and Cell Death of Jurkat T Cells
      Hiromi AMANO, Masashi YAMAGIWA, Tetsuyuki AKAO, Eiichi MIZUKI, Michio OHBA, Hiroshi SAKAI
      Bioscience, Biotechnology, and Biochemistry 2005 69 11
    • Acidification induces Bax translocation to the mitochondria and promotes ultraviolet light-induced apoptosis
      Lin Yang, Yongyu Mei, Qifeng Xie, Xiaoyan Han, Fucheng Zhang, Lin Gu, Yufeng Zhang, Youming Chen, Gang Li, Zhiliang Gao
      Cellular and Molecular Biology Letters 2008 13 1
    • Apoptosis and Cancer
      C. Michael Knudson, Nicholas M. Brown
      2008
    • Apoptosis of mink lung epithelial cells by co-treatment of low-dose staurosporine and transforming growth factor-β1 depends on the enhanced TGF-β signaling and requires the decreased phosphorylation of PKB/Akt
      Eun Mi Ju, Kyung-Chul Choi, Seung-Hee Hong, Chang-Hun Lee, Byung-Chul Kim, Seong-Jin Kim, In-Hoo Kim, Seok Hee Park
      Biochemical and Biophysical Research Communications 2005 328 4
    • Equilibrative nucleoside transporter 3 depletion in β-cells impairs mitochondrial function and promotes apoptosis: Relationship to pigmented hypertrichotic dermatosis with insulin-dependent diabetes
      B. Liu, A. Czajka, A.N. Malik, K. Hussain, P.M. Jones, S.J. Persaud
      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2015 1852 10
    • Graves-Basedow Disease Goiter: A Model of Bax-Bcl2 Regulated Apoptosis
      FRANÇOISE LABAT-MOLEUR, OLIVIER CHABRE, CHRISTIANE GUILLERMET, PHILIPPE CHAFFANJON, FRÉDÉRIQUE BLUMET-RONDEU, ALAIN BAUCHET, BRIGITTE FRANC, ELISABETH BRAMBILLA, IVAN BACHELOT, JACQUES EMILE DUMONT, ADRIEN NEGOESCU
      Thyroid 1999 9 5
    • Naturally occurring cell death during postnatal development of rat skeletal muscle
      Carmen De Torres, Francina Munell, Manuel Roig, Jaume Reventós, Alfons Macaya
      Muscle & Nerve 2002 26 6
    • Neuroprotective Activity of Cerebrosides from Typhonium giganteum by Regulating Caspase-3 and Bax/Bcl-2 Signaling Pathways in PC12 Cells
      Yang Jin, Jun-Ting Fan, Xiao-Ling Gu, Li-Ying Zhang, Jing Han, Shu-Hu Du, Ai-Xia Zhang
      Journal of Natural Products 2017 80 6
    • Rapid Microfluidic Perfusion Enabling Kinetic Studies of Lipid Ion Channels in a Bilayer Lipid Membrane Chip
      Chenren Shao, Bing Sun, Marco Colombini, Don L. DeVoe
      Annals of Biomedical Engineering 2011 39 8
    • Taurine 6
      Ewa Kontny, Magdalena Chorąży-Massalska, Weronika Rudnicka, Janusz Marcinkiewicz, Włodzimierz Maśliński
      2006 583
    • The Cytokine, Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF), Can Deliver Bcl-XL as an Extracellular Fusion Protein to Protect Cells from Apoptosis and Retain Differentiation Induction
      Antonella Antignani, Richard J. Youle
      Journal of Biological Chemistry 2007 282 15
    • Truncated RAR beta isoform enhances proliferation and retinoid resistance
      Mari E. Swift, Brett Wallden, Elizabeth A. Wayner, Karen Swisshelm
      Journal of Cellular Physiology 2006 209 3
    • Apoptosis and Development
      Mahendra Seervi, Ding Xue
      2015 114
    • BH3-only proteins Noxa, Bik, Bmf, and Bid activate Bax and Bak indirectly when studied in yeast model
      Gabriela Gérecová, Jana Kopanicová, Petra Jaká, Lucia Běhalová, Barbora Juhásová, Ingrid Bhatia-Kiššová, Michael Forte, Peter Polčic, Marek Mentel
      FEMS Yeast Research 2013 13 8
    • Bcl-xL inhibits Bax-induced alterations in mitochondrial respiration and calcium release
      A.V.F. Teles, R.P. Ureshino, D.J. Dorta, G.S. Lopes, Y.-T. Hsu, S.S. Smaili
      Neuroscience Letters 2008 442 2
    • Caspase Inhibition Blocks Cell Death and Results in Cell Cycle Arrest in Cytokine-deprived Hematopoietic Cells
      Nicholas M. Brown, Sean M. Martin, Nick Maurice, Tomomi Kuwana, C. Michael Knudson
      Journal of Biological Chemistry 2007 282 4
    • Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells
      Haifeng Hou, Ru Zhou, An Li, Cheng Li, Qunwei Li, Jianbao Liu, Baofa Jiang
      Environmental Toxicology and Pharmacology 2014 37 2
    • Conservation and divergence of mitochondrial apoptosis pathway in the Pacific oyster, Crassostrea gigas
      Yingxiang Li, Linlin Zhang, Tao Qu, Xueying Tang, Li Li, Guofan Zhang
      Cell Death & Disease 2017 8 7
    • Effects of a catechol-O-methyltransferase inhibitor on catechol estrogen-induced cellular transformation, chromosome aberrations and apoptosis in Syrian hamster embryo cells
      Yutaka Hirose, Takeo W. Tsutsui, Maki Ohno, J. Carl Barrett, Takeki Tsutsui
      International Journal of Cancer 2007 120 8
    • Handbook of the Biology of Aging
      Stephen E. Alway, Michael R. Morissette, Parco M. Siu
      2011
    • Insights into the structural stability of Bax from molecular dynamics simulations at high temperatures
      Jorge Luis Rosas-Trigueros, José Correa-Basurto, Claudia Guadalupe Benítez-Cardoza, Absalom Zamorano-Carrillo
      Protein Science 2011 20 12
    • Interleukins
      Jeffrey Jong‐Young Yen, Hsin‐Fang Yang‐Yen
      2006 74
    • Mycobacterium indicus pranii Supernatant Induces Apoptotic Cell Death in Mouse Peritoneal Macrophages In Vitro
      Rajeev Kumar Pandey, Kunal H. Bhatt, Yogesh Dahiya, Ajit Sodhi, Niyaz Ahmed
      PLoS ONE 2011 6 2
    • Patrinia scabiosaefolia induces mitochondrial-dependent apoptosis in a mouse model of colorectal cancer
      LIYA LIU, ALING SHEN, YOUQIN CHEN, LIHUI WEI, JIUMAO LIN, THOMAS J. SFERRA, ZHENFENG HONG, JUN PENG
      Oncology Reports 2013 30 2
    • Polyalthia longifolia Methanolic Leaf Extracts (PLME) induce apoptosis, cell cycle arrest and mitochondrial potential depolarization by possibly modulating the redox status in hela cells
      Soundararajan Vijayarathna, Chern Ein Oon, Yeng Chen, Jagat R. Kanwar, Sreenivasan Sasidharan
      Biomedicine & Pharmacotherapy 2017 89
    • Prevention of apoptosis by the interaction between FIH1 and Bax
      Biao Yan, Men Kong, Yi-han Chen
      Molecular and Cellular Biochemistry 2011 348 1-2
    • Serum suppresses myeloid progenitor apoptosis by regulating iron homeostasis
      Kirsteen Maclean, Hui Yang, John L. Cleveland
      Journal of Cellular Biochemistry 2001 82 1
    • The Bax carboxy-terminal hydrophobic helix does not determine organelle-specific targeting but is essential for maintaining Bax in an inactive state and for stable mitochondrial membrane insertion
      Stephanie E. Brock, Chi Li, Binks W. Wattenberg
      Apoptosis 2010 15 1
    • Torilis japonica extract-generated intracellular ROS induces apoptosis by reducing the mitochondrial membrane potential via regulation of the AMPK-p38 MAPK signaling pathway in HCT116 colon cancer
      Guen Tae Kim, Se Hee Lee, Young Min Kim
      International Journal of Oncology 2016 49 3
    • ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells
      Min Yang, Mingcan Yu, Dongyin Guan, Jinfa Gu, Xin Cao, Weiyun Wang, Shu Zheng, Yingying Xu, Zonghou Shen, Xinyuan Liu
      Journal of Cellular Biochemistry 2010 110 3
    • Amyloid Fibrils Formed by the Programmed Cell Death Regulator Bcl-xL
      Alexandre Chenal, Charlotte Vendrely, Heidi Vitrac, Johanna C. Karst, Alexis Gonneaud, Clément E. Blanchet, Sylvain Pichard, Elisabeth Garcia, Bénédicte Salin, Patrice Catty, Daniel Gillet, Nicolas Hussy, Christel Marquette, Christine Almunia, Vincent Forge
      Journal of Molecular Biology 2012 415 3
    • Anti- and Pro-apoptotic Bcl2 Proteins Distribution and Metabolic Profile in Human Coronary Aorta Endothelial Cells Before and After HypPDT
      Mária Maslaňáková, Lucia Balogová, Pavol Miškovský, Ružena Tkáčová, Katarína Štroffeková
      Cell Biochemistry and Biophysics 2016 74 3
    • Antioxidant-Mediated Reversal of Oxidative Damage in Mouse Modeling of Complex I Inhibition
      Kodeeswaran Parameshwaran, Michael H. Irwin, Kosta Steliou, Vishnu Suppiramaniam, Carl A. Pinkert
      Drug Development Research 2015 76 2
    • Canine Bcl-xL Gene and Its Expression in Tumor Cell Lines
      Junichi SANO, Keisuke OGUMA, Rui KANO, Atsuhiko HASEGAWA
      Journal of Veterinary Medical Science 2003 65 1
    • Ensemble Properties of Bax Determine Its Function
      Adeline Y. Robin, Sweta Iyer, Richard W. Birkinshaw, Jarrod Sandow, Ahmad Wardak, Cindy S. Luo, Melissa Shi, Andrew I. Webb, Peter E. Czabotar, Ruth M. Kluck, Peter M. Colman
      Structure 2018 26 10
    • Ethanol withdrawal hastens the aging of cytochrome c oxidase
      Marianna E. Jung, Xiaohua Ju, Daniel B. Metzger, James W. Simpkins
      Neurobiology of Aging 2012 33 3
    • HDAC inhibitors induce apoptosis but not cellular senescence in Gadd45α-deficient E1A+Ras cells
      M.V. Igotti Abramova, A.K. Pojidaeva, E.A. Filippova, O.O. Gnedina, S.B. Svetlikova, V.A. Pospelov
      The International Journal of Biochemistry & Cell Biology 2014 51
    • Interferon tau-induced hepatocyte apoptosis in sheep
      Hun-Taek Kim, George Stoica, Fuller W. Bazer, Troy L. Ott
      Hepatology 2000 31 6
    • Lack of correlation between apoptosis and DNA single-strand breaks in X-irradiated human peripheral blood mononuclear cells in the course of ageing
      Christian Chauvin, Evelyn Heidenreich, Kristina Elmendorff-Dreikorn, Hanoch Slor, Joachim Kutzner, Renato Batel, Heinz C Schröder
      Mechanisms of Ageing and Development 1998 106 1-2
    • Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis
      Margaret E. Maes, Cassandra L. Schlamp, Robert W. Nickells, Dhyan Chandra
      PLOS ONE 2017 12 9
    • Neonatal monocytes express antiapoptotic pattern of Bcl-2 proteins and show diminished apoptosis upon infection with Escherichia coli
      Anja Leiber, Benjamin Graf, Bärbel Spring, Justine Rudner, Natascha Köstlin, Thorsten W. Orlikowsky, Christian F. Poets, Christian Gille
      Pediatric Research 2014 76 2
    • Programmed Cell Death,General Principles forStudying Cell Death, Part A
      Soraya S. Smaili, Tatiana R. Rosenstock, Yi‐Te Hsu
      2008 442
    • Purification and characterization a polysaccharide from Hedyotis diffusa and its apoptosis inducing activity toward human lung cancer cell line A549
      Liyao Lin, Keluo Cheng, Zhanqiang Xie, Chunyuan Chen, Lin Chen, Yidong Huang, Zhu Liang
      International Journal of Biological Macromolecules 2019 122
    • The Effects of Davallic Acid from Davallia divaricata Blume on Apoptosis Induction in A549 Lung Cancer Cells
      An-Sheng Cheng, We-Chang Chang, Yu-Hsiang Cheng, Kai-Yu Chen, Kai-Hsien Chen, Tsu-Liang Chang
      Molecules 2012 17 11
    • Tilman Oltersdorf, Lawrence C. Fritz
      1998 33
    • A Feedback Mechanism to Control Apoptosis Occurs in the Digestive Gland of the Oyster Crassostrea gigas Exposed to the Paralytic Shellfish Toxins Producer Alexandrium catenella
      Jean-Luc Rolland, Walid Medhioub, Agnes Vergnes, Celina Abi-khalil, Véronique Savar, Eric Abadie, Estelle Masseret, Zouher Amzil, Mohamed Laabir
      Marine Drugs 2014 12 9
    • Acute Neuronal Injury
      Bogdan A. Stoica, Alan I. Faden
      2010
    • Apoptosis and Cancer Chemotherapy
      Douglas R. Green, Helen M. Beere
      1999
    • Bax-mediated mitochondrial membrane permeabilization after heat treatment is caspase-2 dependent
      E. H. A. Nijhuis, S. Le Gac, A. A. Poot, J. Feijen, I. Vermes
      International Journal of Hyperthermia 2008 24 4
    • Domain Interaction Studies of Herpes Simplex Virus 1 Tegument Protein UL16 Reveal Its Interaction with Mitochondria
      Pooja Chadha, Akua Sarfo, Dan Zhang, Thomas Abraham, Jillian Carmichael, Jun Han, John W. Wills, Richard M. Longnecker
      Journal of Virology 2017 91 2
    • HepG2 cells infected with Klebsiella pneumoniae show DNA laddering at apoptotic and necrotic stages
      Pei-Yin Yang, Wen-Xin Chen, Fong-Yin Chang, Hui-Wen Chen, Chun-Hung Lin, Yu-Chun Hsu, June Hsieh Wu
      Apoptosis 2012 17 2
    • Interaction of cellular proteins with BCL-xL targeted to cytoplasmic inclusion bodies in adenovirus infected cells
      T. Subramanian, S. Vijayalingam, M. Kuppuswamy, G. Chinnadurai
      Virology 2015 483
    • K252a suppresses neuronal cells apoptosis through inhibiting the translocation of Bax to mitochondria induced by the MLK3/JNK signaling after transient global brain ischemia in rat hippocampal CA1 subregion
      Qing Wang, Xiao-Hui Yin, Yong Liu, Guang-Yi Zhang
      Journal of Receptors and Signal Transduction 2011 31 4
    • Mitochondrial VDAC2 and cell homeostasis: highlighting hidden structural features and unique functionalities
      Svetlana Rajkumar Maurya, Radhakrishnan Mahalakshmi
      Biological Reviews 2017 92 4
    • Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner
      Seung-Wook Ryu, Kyungsun Choi, Jong-Hwan Park, Yeong-Min Park, Sunchang Kim, Chulhee Choi
      Cancer Letters 2012 323 1
    • Newcastle disease virus strain AF2240 as an oncolytic virus: A review
      Jeevanathan Kalyanasundram, Aini Hamid, Khatijah Yusoff, Suet Lin Chia
      Acta Tropica 2018 183
    • Retroviral Immunotoxin Gene Therapy of Leukemia in Mice Using Leukemia-Specific T Cells Transduced with an Interleukin-3/Bax Fusion Protein Gene
      Daniel A. Vallera, Ni Jin, Yanqun Shu, Angela Panoskaltsis-Mortari, Ameeta Kelekar, Wei Chen
      Human Gene Therapy 2003 14 18
    • Static magnetic field enhances the anticancer efficacy of capsaicin on HepG2 cells via capsaicin receptor TRPV1
      Wei-Ting Chen, Guan-Bo Lin, Shu-Hui Lin, Chueh-Hsuan Lu, Chih-Hsiung Hsieh, Bo-Lun Ma, Chih-Yu Chao, Robert M. Lafrenie
      PLOS ONE 2018 13 1
    • UVB-Induced Murine Bone Marrow Derived Macrophages and Apoptosis
      Girish K. Srivastava, Guadalupe Zaldívar Lelo de Larrea
      Immunological Investigations 2008 37 4
    • Voltage-Dependent Anion Channel 1(VDAC1) Participates the Apoptosis of the Mitochondrial Dysfunction in Desminopathy
      Huanyin Li, Lan Zheng, Yanqing Mo, Qi Gong, Aihua Jiang, Jing Zhao, Zhefeng Meng
      PLOS ONE 2016 11 12
    • Apoptosis in Lymphocytes of Pancreatic Cancer Patients: Influence of Preoperative Enteral Immunonutrition and Extensive Surgery
      Robert Słotwiński, Waldemar Olszewski, Maciej Słodkowski, Gustaw Lech, Marzanna Zaleska, Sylwia Kędziora, Anna Włuka, Anna Domaszewska, Sylwia Słotwińska, Wojciech Krasnodębski, Zdzisław Wójcik
      Archivum Immunologiae et Therapiae Experimentalis 2011 59 5
    • Brain Repair
      Kerstin Krieglstein
      2006 557
    • C-terminal tail insertion of Bcl-xL in membrane occurs via partial unfolding and refolding cycle associating microsolvation
      Atanu Maity, Souvik Sinha, Debabani Ganguly, Shubhra Ghosh Dastidar
      Physical Chemistry Chemical Physics 2016 18 34
    • Matters of life and death: programmed cell death at Cold Spring Harbor
      Suzanne Cory, Jerry M Adams
      Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1998 1377 2
    • Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism
      Jasdeep Mann, John Maringa Githaka, Timothy W. Buckland, Ning Yang, Rachel Montpetit, Namrata Patel, Lei Li, Shairaz Baksh, Roseline Godbout, Hélène Lemieux, Ing Swie Goping
      Oncogene 2019 38 18
    • Protective Effect of Combined Caffeic Acid Phenethyl Ester and Bevacizumab Against Hydrogen Peroxide-Induced Oxidative Stress in Human RPE Cells
      Erdem Dinc, Lokman Ayaz, Akif Hakan Kurt
      Current Eye Research 2017 42 12
    • Biologically distinct conformations of Bcl-x can be resolved using 2D isoelectric focusing
      Karen R. Rockwell, Brigitte T. Huber
      Molecular Immunology 2009 46 8-9
    • Differential expression of the Bcl-2 and Bax isoforms in CD19 positive B-lymphocytes isolated from patients diagnosed with chronic lymphocytic leukaemia
      Reza Ghassemifar, Luke Forster, Jill Finlayson, Tony Calogero, Brad Augustson, David Joske, Gavin Cull
      Pathology 2012 44 7
    • Generation and Characterization of Species-Specific Anti-Bcl-XL Monoclonal Antibodies
      Yi-Te Hsu, Qi Hou, Eugene Cymbalyuk, Richard Youle
      Hybridoma and Hybridomics 2003 22 2
    • Interferon-γ Prevents Apoptosis in Epstein-Barr Virus-Infected Natural Killer Cell Leukemia in an Autocrine Fashion
      Shin-ichi Mizuno, Koichi Akashi, Koichi Ohshima, Hiromi Iwasaki, Toshihiro Miyamoto, Naoyuki Uchida, Tsunefumi Shibuya, Mine Harada, Masahiro Kikuchi, Yoshiyuki Niho
      Blood 1999 93 10
    • Involution dependent changes in distribution and localization of bax, survivin, caspase-3, and calpain-1 in the rat endometrium
      Emel Alan, Narin Liman
      Microscopy Research and Technique 2016 79 4
    • Lipid-modulation of membrane insertion and refolding of the apoptotic inhibitor Bcl-xL
      Victor Vasquez-Montes, Mauricio Vargas-Uribe, Nitin K. Pandey, Mykola V. Rodnin, Ralf Langen, Alexey S. Ladokhin
      Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2019 1867 7-8
    • Neuronal and Vascular Plasticity
      Kenneth Maiese, Zhao Zhong Chong, Jing-Qiong Kang
      2003
    • Participation of GATA-3 in regulation of bone healing through transcriptional upregulation of bcl-xL expression
      Mei-Hsiu Liao, Pei-I Lin, Wei-Pin Ho, Wing P Chan, Ta-Liang Chen, Ruei-Ming Chen
      Experimental & Molecular Medicine 2017 49 11
    • Pingyangmycin and Bleomycin Share the Same Cytotoxicity Pathway
      Yanli He, Ying Lan, Yong Liu, Haibo Yu, Zhangrun Han, Xiulian Li, Lijuan Zhang
      Molecules 2016 21 7
    • Quranic Verse No. 8 of Surat Al-Jumu’ah Describes Cancer as a Complete and Accurate Description and Leads Us to Determine the True Cause of Cancer. “Part-1”
      Mahmoud Saad Mohamed El-Khodary
      CellBio 2018 07 01
    • Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane
      Trey Farmer, Katelyn L. O’Neill, Naava Naslavsky, Xu Luo, Steve Caplan, Thomas D. Fox
      Molecular Biology of the Cell 2019 30 10
    • Subcellular Distribution and Redistribution of Bcl-2 Family Proteins in Human Leukemia Cells Undergoing Apoptosis
      Li Jia, Marion G. Macey, Yuzhi Yin, Adrian C. Newland, Stephen M. Kelsey
      Blood 1999 93 7
    • Survival and phenotypic characteristics of axotomized neurons in spinal ganglia
      Yu. A. Chelyshev, I. S. Raginov, D. S. Guseva, R. F. Masgutov
      Neuroscience and Behavioral Physiology 2005 35 5
    • The Process of Apoptosis in a Holocrine Gland as Shown by the Avian Uropygial Gland
      Narin Liman, Emel Alan
      The Anatomical Record 2013 296 3
    • The occupation of intestinal epithelium by Trichinella spiralis in BALB/C mice is not associated with local manifestation of apoptosis related factors
      Rositsa Milcheva, Svetlozara Petkova, Zuzana Hurniková, Pavol Janega, Pavel Babál
      Parasitology Research 2013 112 11
    • Achyranthes bidentatapolypeptides confer neuroprotection through inhibition of reactive oxygen species production, Bax expression, and mitochondrial dysfunction induced by overstimulation of N-methyl-D-aspartate receptors
      Hongmei Shen, Ying Yuan, Fei Ding, Nan Hu, Jie Liu, Xiaosong Gu
      Journal of Neuroscience Research 2009
    • Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasi
      M.L. Campo
      2009
    • BH3-only proteins: The death-puppeteer's wires
      Fabio Ghiotto, Franco Fais, Silvia Bruno
      Cytometry Part A 2009 9999A
    • Balancing Apoptosis and Autophagy for Parkinson’s Disease Therapy: Targeting BCL-2
      Jia Liu, Weijing Liu, Hui Yang
      ACS Chemical Neuroscience 2019 10 2
    • Chemopreventive potential of fungal taxol against 7, 12-dimethylbenz[a]anthracene induced mammary gland carcinogenesis in Sprague Dawley rats
      Kathamuthu Gokul Raj, Ranganathan Chidambaram, Krishnamoorthy Varunkumar, Vilwanathan Ravikumar, Mohan Pandi
      European Journal of Pharmacology 2015 767
    • Dysfunctional high density lipoprotein failed to rescue the function of oxidized low density lipoprotein-treated endothelial progenitor cells: a novel index for the prediction of HDL functionality
      Chun-Ming Shih, Feng-Yen Lin, Jong-Shiuan Yeh, Yi-Wen Lin, Shih-Hurng Loh, Nai-Wen Tsao, Hironori Nakagami, Ryuichi Morishita, Tatsuya Sawamura, Chi-Yuan Li, Cheng-Yen Lin, Chun-Yao Huang
      Translational Research 2019 205
    • Effects of Butyrate on Colorectal Cancer
      Ji Young Jin, Kwang Keun Cho, In Soon Choi
      Journal of Life Science 2013 23 1
    • Essentials of Apoptosis
      Man Jiang, Craig Brooks, Guie Dong, Xiaoning Li, Hong-Min Ni, Xiao-Ming Yin, Zheng Dong
      2009
    • LPLI inhibits apoptosis upstream of Bax translocation via a GSK-3β-inactivation mechanism
      Lingling Zhang, Yingjie Zhang, Da Xing
      Journal of Cellular Physiology 2010
    • Livistona chinensis seed suppresses hepatocellular carcinoma growth through promotion of mitochondrial-dependent apoptosis
      WEI LIN, JINYAN ZHAO, ZHIYUN CAO, QUNCHUAN ZHUANG, LIANGPU ZHENG, QIAOYAN CAI, DAXIN CHEN, LILI WANG, ZHENFENG HONG, JUN PENG
      Oncology Reports 2013 29 5
    • Mitochondrial function and abnormalities implicated in the pathogenesis of ASD
      Frank J. Castora
      Progress in Neuro-Psychopharmacology and Biological Psychiatry 2019 92
    • Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis
      Chiaki Okuma, Takefumi Kaketa, Atsuhiko Hikita, Koichi Matsuda, Masaki Nakamura, Yuichi Nagase, Yasushi Oshima, Mitsuyasu Iwasawa, Yusuke Nakamura, Hisashi Kurosawa, Kozo Nakamura, Sakae Tanaka
      Journal of Bone and Mineral Metabolism 2008 26 6
    • Repurposing L-Menthol for Systems Medicine and Cancer Therapeutics? L-Menthol Induces Apoptosis through Caspase 10 and by Suppressing HSP90
      Uzma Faridi, Sunita S. Dhawan, Shaifali Pal, Sanchita Gupta, Ashutosh K. Shukla, Mahendra P. Darokar, Ashok Sharma, Ajit K. Shasany
      OMICS: A Journal of Integrative Biology 2016 20 1
    • The importance of evolutionarily conserved C-terminal basic residues for the stability of proapoptotic Bax protein
      Jorge L. Rosas-Trigueros
      FEBS Open Bio 2016 6 10
    • Tocotrienols
      Paul Sylvester
      2008
    • E2F1 interacts with BCL ‐ xL and regulates its subcellular localization dynamics to trigger cell death
      Céline Vuillier, Steven Lohard, Aurélie Fétiveau, Jennifer Allègre, Cémile Kayaci, Louise E King, Frédérique Braun, Sophie Barillé‐Nion, Fabien Gautier, Laurence Dubrez, Andrew P Gilmore, Philippe P Juin, Laurent Maillet
      EMBO reports 2018 19 2
    • Aberrant mitochondrial function in ageing and cancer
      Julia C. Whitehall, Laura C. Greaves
      Biogerontology 2019
    • Advancement in the Pathophysiology of Cerebral Stroke
      Sumedha Mukherjee, Amit Kumar Tripathi, Gaurav Kumar, Ranjana Patnaik, Nirav Dhanesha, Divya Mishra
      2019
    • Advances in Membrane Proteins
      Yu Cao, Ying Xia
      2018
    • Amiodarone’s major metabolite, desethylamiodarone, induces apoptosis in human cervical cancer cells
      Zita Bognar, Katalin Fekete, Rita Bognar, Aliz Szabo, Reka A. Vass, Balazs Sumegi
      Canadian Journal of Physiology and Pharmacology 2018 96 10
    • Anticarcinogenic effect of indole-3-carbinol (I3C) on human hepatocellular carcinoma SNU449 cells
      CM Lee, S-H Park, MJ Nam
      Human & Experimental Toxicology 2019 38 1
    • Apoptosis and Cancer Chemotherapy
      Jean-Claude Martinou, Bruno Antonsson
      1999
    • Apoptosis and Cancer Chemotherapy
      Yi-Te Hsu, Richard Youle
      1999
    • Apoptosis in Cardiac Biology
      Klaus Schlottmann, Jürgen Schölmerich
      2000 5
    • Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
      Sanjeev Shangary, Christopher L. Oliver, Daniel E. Johnson
      2005
    • BCL-2 Family Proteins
      Zhou Dai, Jonathan R. Lai
      2019 1877
    • Bax to the future – A novel, high-yielding approach for purification and expression of full-length Bax protein for structural studies
      Artur P.G. Dingeldein, Mikael J. Lindberg, Jörgen Ådén, Xueyin Zhong, Raphael Stoll, Gerhard Gröbner
      Protein Expression and Purification 2019 158
    • CRISPR/Cas9 genome editing of SLC37A4 gene elucidates the role of molecular markers of endoplasmic reticulum stress and apoptosis in renal involvement in glycogen storage disease type Ib
      Anita Skakic, Marina Andjelkovic, Natasa Tosic, Kristel Klaassen, Maja Djordjevic, Sonja Pavlovic, Maja Stojiljkovic
      Gene 2019 703
    • Cancer Drug Resistance
      Varsha Gandhi, Beatriz Sanchez-Vega
      2006
    • Cell Engineering
      Jeffrey Varner, Martin Fussenegger
      2005 4
    • Chemoprotective Effects of Resveratrol Against Diethylnitrosamine Induced Hepatocellular Carcinoma in Wistar Rats
      Xin you Su, Jian Qiang Zhao, Nan Li, Mukesh Kumar, Ai mei Ou yang
      International Journal of Pharmacology 2019 15 5
    • Completion of BAX recruitment correlates with mitochondrial fission during apoptosis
      M. E. Maes, J. A. Grosser, R. L. Fehrman, C. L. Schlamp, R. W. Nickells
      Scientific Reports 2019 9 1
    • DNA Topoisomerases and Cancer
      Olivier Sordet, Stéphanie Solier
      2012
    • Deregulated miR-29b-3p Correlates with Tissue-Specific Activation of Intrinsic Apoptosis in An Animal Model of Amyotrophic Lateral Sclerosis
      Klatt, Theis, Hahn, Theiss, Matschke
      Cells 2019 8 9
    • Effect of Rheum undulatum Linne extract and Glycyrriza uralensis Fischer extract against arachidonic acid and iron-induced oxidative stress in HepG2 cell and CCl4-induced liver injury in mice
      Eun Hye Lee, Su Youn Baek, Kwang-Youn Kim, Seul-Gi Lee, Sang Chan Kim, Hyeong Sik Lee, Young Woo Kim
      Herbal Formula Science 2016 24 3
    • Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer’s Disease
      L.E. Henderson, M.A. Abdelmegeed, S.H. Yoo, S.G. Rhee, X. Zhu, M.A. Smith, R.Q. Nguyen, G. Perry, B.J. Song
      The Open Neurology Journal 2017 11 1
    • Essentials of Apoptosis
      Li Bai, Jinzhao Wang, Xiao-Ming Yin, Zheng Dong
      2003
    • Ethanol increases manganese—Induced spatial learning and memory deficits via oxidative/nitrosative stress induced p53 dependent/independent hippocampal apoptosis
      Kpobari W. Nkpaa, Benjamin A. Amadi, Matthew O. Wegwu, Ebenezer O. Farombi
      Toxicology 2019 418
    • Genetic Engineering: Principles and Methods
      Collin C. Q. Vu, John A. Cidlowski
      2002 23
    • Hematologic Malignancies: Myelodysplastic Syndromes
      Philip Nivatpumin, Steven Gore
      2006
    • High Expression of ABRACL Is Associated with Tumorigenesis and Affects Clinical Outcome in Gastric Cancer
      Dazhi Wang, HuaQiang Liu, Chunling Ren, Lanying Wang
      Genetic Testing and Molecular Biomarkers 2019 23 2
    • Induction of Apoptosis by Vitamin E Succinate in Human Erythroleukemia K562 Cells
      Chang-Deug Jang, Jong-Myoung Kim, Won-Geun An, Hye-Ryoun Park
      Journal of Life Science 2007 17 7
    • Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis
      Naveed Sabir, Tariq Hussain, Yi Liao, Jie Wang, Yinjuan Song, Muhammad Shahid, Guangyu Cheng, Mazhar Hussain Mangi, Jiao Yao, Lifeng Yang, Deming Zhao, Xiangmei Zhou
      Cells 2019 8 5
    • Mammalian Toxicology
      Heather A. Himburg, John P. Chute
      2015
    • Molecular Mechanisms of Programmed Cell Death
      Jun Jin, Jianxin Dai, Jian Zhao, Yajun Guo
      2003
    • Neuronal Death by Accident or by Design
      O. Terradillos, X. Roucou, S. Da Cruz, B. Sanchez, J.-C. Martinou
      2001
    • Neuronal Death by Accident or by Design
      G. V. Putcha, M. Deshmukh, E. M. Johnson
      2001
    • On the release of cytochromec from mitochondria during cell death signaling
      Maria L. R. Lim, May-Ghee Lum, Tania M. Hansen, Xavier Roucou, Phillip Nagley
      Journal of Biomedical Science 2002 9 6
    • Oxidation: The Cornerstone of Carcinogenesis
      John C. Stavridis
      2008
    • Proteases in Apoptosis: Pathways, Protocols and Translational Advances
      Nitu Singh, Kakoli Bose
      2015
    • Recovery of the Cholangiocytes After Ischemia and Reperfusion Injury: Ultra-Structural, Hystological and Molecular Assessment in Rats
      Thiago P.A. Aloia, Bruno Cogliati, Janaina M. Monteiro, Anna C.K. Goldberg, Paolo R. de Oliveira Salvalaggio
      Journal of Clinical and Experimental Hepatology 2018 8 4
    • Roles of plant hormones and anti-apoptosis genes during drought stress in rice (Oryza sativa L.)
      Mohammad Ubaidillah, Fika Ayu Safitri, Jun-Hyeon Jo, Sang-Kyu Lee, Adil Hussain, Bong-Gyu Mun, Il Kyung Chung, Byung-Wook Yun, Kyung-Min Kim
      3 Biotech 2016 6 2
    • SINGLE CELL IMAGING OF BAX TRANSLOCATION DURING APOPTOSIS INDUCED BY PHOTOFRIN-PDT
      FEIFAN ZHOU, DA XING, WEI R. CHEN
      Journal of Innovative Optical Health Sciences 2009 02 02
    • Sarcopenia – Age-Related Muscle Wasting and Weakness
      Stephen E. Alway, Parco M. Siu
      2011
    • Stoichiometry and regulation network of Bcl-2 family complexes quantified by live-cell FRET assay
      Fangfang Yang, Wenfeng Qu, Mengyan Du, Zihao Mai, Bin Wang, Yunyun Ma, Xiaoping Wang, Tongsheng Chen
      Cellular and Molecular Life Sciences 2019
    • Trends in Stem Cell Proliferation and Cancer Research
      Fabio Ghiotto, Claudya Tenca, Franco Fais, Silvia Bruno
      2013
    • WITHDRAWN: Reprint of: Variations in the rheostat model of apoptosis: What studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins
      Robert W. Nickells
      Experimental Eye Research 2011
    • WITHDRAWN: Varying levels and function of several biological macromolecules in myocardium
      JiaYi Zhang, Wei Tao
      International Journal of Biological Macromolecules 2013

    Article usage

    Article usage: January 1999 to December 2019

    AbstractFullPdf
    Jan 199951324
    Feb 19993822
    Mar 199931943
    Apr 199921927
    May 199931120
    Jun 199951221
    Jul 199951934
    Aug 199941122
    Sep 199931231
    Oct 199982940
    Nov 199942340
    Dec 199951120
    Total 199950187344
    Jan 2000101336
    Feb 200031834
    Mar 200064049
    Apr 200042430
    May 200021831
    Jun 200091440
    Jul 200042436
    Aug 200063555
    Sep 200093457
    Oct 200093736
    Nov 200074050
    Dec 200021945
    Total 200071316499
    Jan 200183052
    Feb 2001101730
    Mar 200152949
    Apr 200173549
    May 200162435
    Jun 2001112649
    Jul 200172844
    Aug 200172437
    Sep 2001113257
    Oct 200184146
    Nov 200184947
    Dec 200131642
    Total 200191351537
    Jan 200294545
    Feb 200263127
    Mar 200283748
    Apr 200283749
    May 200294325
    Jun 2002153234
    Jul 200253527
    Aug 200252832
    Sep 200241736
    Oct 200254142
    Nov 2002103348
    Dec 200232732
    Total 200287406445
    Jan 2003103858
    Feb 2003144952
    Mar 2003123337
    Apr 2003133539
    May 2003114449
    Jun 2003154244
    Jul 2003104242
    Aug 2003173145
    Sep 2003304843
    Oct 2003252849
    Nov 2003285749
    Dec 2003184855
    Total 2003203495562
    Jan 2004274635
    Feb 2004303736
    Mar 2004417238
    Apr 2004315338
    May 2004365050
    Jun 2004407650
    Jul 2004315522
    Aug 2004444344
    Sep 2004317057
    Oct 2004415643
    Nov 2004409561
    Dec 2004463738
    Total 2004438690512
    Jan 2005413745
    Feb 2005314742
    Mar 2005233941
    Apr 2005172642
    May 2005133825
    Jun 2005112823
    Jul 2005194737
    Aug 2005164933
    Sep 2005131622
    Oct 2005193723
    Nov 2005374642
    Dec 2005213228
    Total 2005261442403
    Jan 200693731
    Feb 2006314026
    Mar 2006122624
    Apr 2006152827
    May 2006214124
    Jun 200692416
    Jul 2006153225
    Aug 2006241615
    Sep 2006344438
    Oct 2006387544
    Nov 2006548545
    Dec 2006236938
    Total 2006285517353
    Jan 2007246343
    Feb 2007248028
    Mar 2007448850
    Apr 2007364439
    May 2007283126
    Jun 2007292331
    Jul 2007211821
    Aug 2007302835
    Sep 2007252330
    Oct 2007283636
    Nov 2007222729
    Dec 2007191937
    Total 2007330480405
    Jan 2008243025
    Feb 2008193631
    Mar 2008252535
    Apr 2008243934
    May 2008173142
    Jun 2008233149
    Jul 200849637
    Aug 2008402830
    Sep 2008451635
    Oct 2008552343
    Nov 2008512446
    Dec 2008462839
    Total 2008418317446
    Jan 2009401824
    Feb 2009412314
    Mar 2009362748
    Apr 2009464850
    May 2009312825
    Jun 2009303224
    Jul 2009372931
    Aug 2009534836
    Sep 2009382230
    Oct 2009264825
    Nov 2009146223
    Dec 2009185425
    Total 2009410439355
    Jan 2010185732
    Feb 201093318
    Mar 2010426233
    Apr 2010512231
    May 2010442729
    Jun 2010322222
    Jul 2010452222
    Aug 2010494141
    Sep 2010434222
    Oct 2010292320
    Nov 2010433625
    Dec 2010362323
    Total 2010441410318
    Jan 2011381618
    Feb 2011292119
    Mar 2011482531
    Apr 2011473626
    May 2011461733
    Jun 2011411930
    Jul 2011243332
    Aug 2011253824
    Sep 2011402723
    Oct 2011426124
    Nov 2011454439
    Dec 2011292819
    Total 2011454365318
    Jan 2012433130
    Feb 2012492830
    Mar 2012462434
    Apr 2012353642
    May 2012533234
    Jun 2012262819
    Jul 2012283214
    Aug 2012323427
    Sep 2012252216
    Oct 2012321525
    Nov 2012372725
    Dec 2012352524
    Total 2012441334320
    Jan 2013452134
    Feb 2013453422
    Mar 2013303246
    Apr 2013622132
    May 2013343421
    Jun 2013422428
    Jul 2013271916
    Aug 2013421330
    Sep 2013361828
    Oct 2013491933
    Nov 2013502537
    Dec 2013261322
    Total 2013488273349
    Jan 2014252720
    Feb 2014282224
    Mar 2014402718
    Apr 2014447828
    May 2014443321
    Jun 2014402628
    Jul 2014511830
    Aug 2014231619
    Sep 2014342715
    Oct 2014323321
    Nov 2014382914
    Dec 2014552212
    Total 2014454358250
    Jan 2015382017
    Feb 2015331212
    Mar 2015442019
    Apr 2015423235
    May 2015702124
    Jun 2015371221
    Jul 201553219
    Aug 2015331516
    Sep 2015491217
    Oct 2015431815
    Nov 2015912628
    Dec 2015481014
    Total 2015581219227
    Jan 2016462318
    Feb 2016773136
    Mar 2016442028
    Apr 2016521815
    May 2016371915
    Jun 2016551916
    Jul 201645179
    Aug 2016482132
    Sep 2016381816
    Oct 2016824934
    Nov 2016642624
    Dec 2016602632
    Total 2016648287275
    Jan 2017452518
    Feb 201730818
    Mar 2017431526
    Apr 2017291112
    May 2017372312
    Jun 2017491717
    Jul 20172097
    Aug 2017241018
    Sep 2017412623
    Oct 2017351816
    Nov 2017241718
    Dec 2017271112
    Total 2017404190197
    Jan 2018201414
    Feb 2018321913
    Mar 2018432921
    Apr 2018292812
    May 2018484022
    Jun 201820276
    Jul 2018353015
    Aug 2018382912
    Sep 201838307
    Oct 2018334121
    Nov 2018216519
    Dec 201816328
    Total 2018373384170
    Jan 2019143516
    Feb 2019141919
    Mar 2019232814
    Apr 2019194820
    May 2019172715
    Jun 2019112419
    Jul 2019142524
    Aug 2019204230
    Sep 2019111597
    Oct 20191414310
    Nov 2019133711
    Dec 2019042
    Total 2019170591187
    Total709880517472
    PreviousNext
    Back to top
    Article Alerts
    Email Article

    Thank you for your interest in spreading the word on PNAS.

    NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

    Enter multiple addresses on separate lines or separate them with commas.
    Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis
    (Your Name) has sent you a message from PNAS
    (Your Name) thought you would like to see the PNAS web site.
    Citation Tools
    Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis
    Yi-Te Hsu, Keith G. Wolter, Richard J. Youle
    Proceedings of the National Academy of Sciences Apr 1997, 94 (8) 3668-3672; DOI: 10.1073/pnas.94.8.3668

    Citation Manager Formats

    • BibTeX
    • Bookends
    • EasyBib
    • EndNote (tagged)
    • EndNote 8 (xml)
    • Medlars
    • Mendeley
    • Papers
    • RefWorks Tagged
    • Ref Manager
    • RIS
    • Zotero
    Request Permissions
    Share
    Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis
    Yi-Te Hsu, Keith G. Wolter, Richard J. Youle
    Proceedings of the National Academy of Sciences Apr 1997, 94 (8) 3668-3672; DOI: 10.1073/pnas.94.8.3668
    del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
    • Tweet Widget
    • Facebook Like
    • Mendeley logo Mendeley
    Proceedings of the National Academy of Sciences: 116 (49)
    Current Issue

    Submit

    Sign up for Article Alerts

    Jump to section

    • Article
      • Abstract
      • MATERIALS AND METHODS
      • RESULTS
      • DISCUSSION
      • Acknowledgments
      • Footnotes
      • ABBREVIATIONS
      • References
    • Figures & SI
    • Info & Metrics
    • PDF

    You May Also be Interested in

    Modulating the body's networks could become mainstream therapy for many health issues. Image credit: The Feinstein Institutes for Medicine Research.
    Core Concept: The rise of bioelectric medicine sparks interest among researchers, patients, and industry
    Modulating the body's networks could become mainstream therapy for many health issues.
    Image credit: The Feinstein Institutes for Medicine Research.
    Adaptations in heart structure and function likely enabled endurance and survival in preindustrial humans. Image courtesy of Pixabay/Skeeze.
    Human heart evolved for endurance
    Adaptations in heart structure and function likely enabled endurance and survival in preindustrial humans.
    Image courtesy of Pixabay/Skeeze.
    Viscoelastic carrier fluids enhance retention of fire retardants on wildfire-prone vegetation. Image courtesy of Jesse D. Acosta.
    Viscoelastic fluids and wildfire prevention
    Viscoelastic carrier fluids enhance retention of fire retardants on wildfire-prone vegetation.
    Image courtesy of Jesse D. Acosta.
    Water requirements may make desert bird declines more likely in a warming climate. Image courtesy of Sean Peterson (photographer).
    Climate change and desert bird collapse
    Water requirements may make desert bird declines more likely in a warming climate.
    Image courtesy of Sean Peterson (photographer).
    QnAs with NAS member and plant biologist Sheng Yang He. Image courtesy of Sheng Yang He.
    Featured QnAs
    QnAs with NAS member and plant biologist Sheng Yang He
    Image courtesy of Sheng Yang He.

    Similar Articles

    Site Logo
    Powered by HighWire
    • Submit Manuscript
    • Twitter
    • Facebook
    • RSS Feeds
    • Email Alerts

    Articles

    • Current Issue
    • Latest Articles
    • Archive

    PNAS Portals

    • Classics
    • Front Matter
    • Teaching Resources
    • Anthropology
    • Chemistry
    • Physics
    • Sustainability Science

    Information

    • Authors
    • Editorial Board
    • Reviewers
    • Press
    • Site Map
    • PNAS Updates

    Feedback    Privacy/Legal

    Copyright © 2019 National Academy of Sciences. Online ISSN 1091-6490