Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

^*The Ludwig Institute for Cancer Research, ^§Department of Medicine, and ^¶Center for Molecular Genetics, University of California, San Diego, La Jolla, CA 92093-0660; and ^‡Molecular Biology and Virology Laboratory, The Salk Institute, La Jolla, CA 92037-1099

Contributed by Webster K. Cavenee

Footnotes

↵† To whom reprint requests should be addressed at: The Ludwig Institute for Cancer Research, 9500 Gilman Drive, La Jolla, CA 92093-0660. e-mail: wbiggs{at}ucsd.edu.

Cited By...

Article usage

Article usage: June 1999 to January 2021

	Abstract	Full	Pdf
Jun 1999	160	145	268
Jul 1999	41	110	147
Aug 1999	7	56	63
Sep 1999	5	74	62
Oct 1999	9	78	66
Nov 1999	7	110	96
Dec 1999	5	26	26
Total 1999	234	599	728
Jan 2000	5	48	44
Feb 2000	2	41	56
Mar 2000	7	57	51
Apr 2000	6	44	34
May 2000	5	44	38
Jun 2000	7	37	39
Jul 2000	5	36	41
Aug 2000	5	30	27
Sep 2000	0	29	31
Oct 2000	4	47	69
Nov 2000	4	52	53
Dec 2000	5	26	40
Total 2000	55	491	523
Jan 2001	7	39	31
Feb 2001	3	54	58
Mar 2001	11	45	44
Apr 2001	7	31	45
May 2001	8	31	35
Jun 2001	5	34	34
Jul 2001	1	25	34
Aug 2001	0	28	35
Sep 2001	8	38	42
Oct 2001	1	34	41
Nov 2001	5	37	41
Dec 2001	6	31	30
Total 2001	62	427	470
Jan 2002	5	30	21
Feb 2002	6	35	38
Mar 2002	1	31	30
Apr 2002	16	45	39
May 2002	13	25	25
Jun 2002	28	31	26
Jul 2002	5	31	22
Aug 2002	2	18	11
Sep 2002	4	16	20
Oct 2002	16	26	17
Nov 2002	5	25	26
Dec 2002	4	16	28
Total 2002	105	329	303
Jan 2003	7	22	27
Feb 2003	13	27	39
Mar 2003	5	18	34
Apr 2003	9	39	28
May 2003	6	34	15
Jun 2003	7	32	46
Jul 2003	12	33	31
Aug 2003	12	32	47
Sep 2003	23	53	56
Oct 2003	36	43	66
Nov 2003	40	72	54
Dec 2003	24	39	34
Total 2003	194	444	477
Jan 2004	38	39	54
Feb 2004	17	40	39
Mar 2004	39	50	49
Apr 2004	38	61	51
May 2004	45	54	40
Jun 2004	43	44	27
Jul 2004	40	54	23
Aug 2004	33	58	30
Sep 2004	44	69	44
Oct 2004	40	52	33
Nov 2004	36	49	22
Dec 2004	16	47	24
Total 2004	429	617	436
Jan 2005	14	32	19
Feb 2005	23	44	27
Mar 2005	20	34	24
Apr 2005	19	42	19
May 2005	27	34	23
Jun 2005	20	26	16
Jul 2005	20	25	14
Aug 2005	16	36	20
Sep 2005	40	23	15
Oct 2005	29	41	33
Nov 2005	21	27	17
Dec 2005	21	38	19
Total 2005	270	402	246
Jan 2006	24	42	19
Feb 2006	35	32	14
Mar 2006	14	32	15
Apr 2006	25	27	13
May 2006	18	26	11
Jun 2006	28	30	19
Jul 2006	30	33	16
Aug 2006	14	26	10
Sep 2006	28	20	15
Oct 2006	19	18	19
Nov 2006	37	37	19
Dec 2006	17	21	19
Total 2006	289	344	189
Jan 2007	27	34	20
Feb 2007	21	22	23
Mar 2007	14	20	31
Apr 2007	10	26	16
May 2007	14	26	21
Jun 2007	17	52	18
Jul 2007	12	19	9
Aug 2007	17	41	14
Sep 2007	19	47	8
Oct 2007	19	40	18
Nov 2007	24	65	23
Dec 2007	12	27	10
Total 2007	206	419	211
Jan 2008	21	34	24
Feb 2008	13	21	13
Mar 2008	23	19	15
Apr 2008	24	20	27
May 2008	23	22	20
Jun 2008	27	25	13
Jul 2008	37	19	17
Aug 2008	35	22	12
Sep 2008	34	20	18
Oct 2008	22	14	13
Nov 2008	23	8	9
Dec 2008	31	13	20
Total 2008	313	237	201
Jan 2009	43	16	20
Feb 2009	29	15	15
Mar 2009	34	26	9
Apr 2009	22	17	11
May 2009	16	17	19
Jun 2009	31	13	12
Jul 2009	10	9	6
Aug 2009	11	11	9
Sep 2009	17	10	9
Oct 2009	20	16	12
Nov 2009	19	23	13
Dec 2009	11	10	7
Total 2009	263	183	142
Jan 2010	11	26	17
Feb 2010	12	12	13
Mar 2010	34	31	14
Apr 2010	25	24	12
May 2010	22	26	15
Jun 2010	21	29	13
Jul 2010	27	18	15
Aug 2010	16	13	11
Sep 2010	11	11	6
Oct 2010	12	30	15
Nov 2010	13	19	10
Dec 2010	14	19	12
Total 2010	218	258	153
Jan 2011	12	23	13
Feb 2011	7	11	9
Mar 2011	13	7	5
Apr 2011	14	9	9
May 2011	23	13	17
Jun 2011	10	12	20
Jul 2011	15	10	12
Aug 2011	12	9	15
Sep 2011	19	13	13
Oct 2011	16	11	12
Nov 2011	9	12	6
Dec 2011	14	15	14
Total 2011	164	145	145
Jan 2012	16	14	11
Feb 2012	15	16	19
Mar 2012	19	15	19
Apr 2012	21	17	15
May 2012	15	12	17
Jun 2012	15	12	11
Jul 2012	16	14	15
Aug 2012	9	10	13
Sep 2012	15	9	20
Oct 2012	19	11	13
Nov 2012	14	9	14
Dec 2012	13	6	11
Total 2012	187	145	178
Jan 2013	20	14	22
Feb 2013	6	6	7
Mar 2013	13	10	24
Apr 2013	25	16	13
May 2013	20	14	13
Jun 2013	17	10	11
Jul 2013	21	15	14
Aug 2013	20	16	13
Sep 2013	12	20	11
Oct 2013	10	17	15
Nov 2013	17	18	12
Dec 2013	15	11	9
Total 2013	196	167	164
Jan 2014	14	11	7
Feb 2014	18	14	14
Mar 2014	20	22	16
Apr 2014	24	52	14
May 2014	28	7	8
Jun 2014	14	7	7
Jul 2014	33	14	12
Aug 2014	36	19	11
Sep 2014	25	24	9
Oct 2014	23	25	9
Nov 2014	21	17	6
Dec 2014	44	18	22
Total 2014	300	230	135
Jan 2015	17	11	18
Feb 2015	9	20	12
Mar 2015	22	13	9
Apr 2015	13	8	3
May 2015	24	9	10
Jun 2015	11	7	9
Jul 2015	20	12	20
Aug 2015	19	10	22
Sep 2015	51	8	9
Oct 2015	10	8	8
Nov 2015	10	7	6
Dec 2015	24	12	13
Total 2015	230	125	139
Jan 2016	31	5	7
Feb 2016	38	10	8
Mar 2016	32	7	11
Apr 2016	12	4	3
May 2016	31	7	23
Jun 2016	28	13	9
Jul 2016	22	9	16
Aug 2016	29	9	9
Sep 2016	16	10	7
Oct 2016	44	11	13
Nov 2016	43	25	8
Dec 2016	26	5	10
Total 2016	352	115	124
Jan 2017	32	11	10
Feb 2017	18	7	7
Mar 2017	29	14	13
Apr 2017	26	14	12
May 2017	24	11	6
Jun 2017	22	6	6
Jul 2017	26	4	10
Aug 2017	41	15	18
Sep 2017	36	11	5
Oct 2017	38	11	10
Nov 2017	22	7	7
Dec 2017	22	13	8
Total 2017	336	124	112
Jan 2018	21	8	10
Feb 2018	25	26	17
Mar 2018	19	18	9
Apr 2018	17	21	11
May 2018	30	35	9
Jun 2018	23	30	11
Jul 2018	34	30	9
Aug 2018	50	48	10
Sep 2018	27	25	8
Oct 2018	7	43	14
Nov 2018	2	68	14
Dec 2018	2	36	8
Total 2018	257	388	130
Jan 2019	2	30	12
Feb 2019	6	25	9
Mar 2019	1	36	10
Apr 2019	7	53	23
May 2019	7	51	20
Jun 2019	7	54	18
Jul 2019	7	35	16
Aug 2019	9	42	22
Sep 2019	7	173	10
Oct 2019	6	125	13
Nov 2019	2	52	12
Dec 2019	3	51	12
Total 2019	64	727	177
Jan 2020	10	58	11
Feb 2020	8	36	14
Mar 2020	6	41	23
Apr 2020	4	25	14
May 2020	7	29	14
Jun 2020	8	15	6
Jul 2020	5	25	17
Aug 2020	3	20	14
Sep 2020	8	58	14
Oct 2020	7	50	22
Nov 2020	11	44	10
Dec 2020	13	42	14
Total 2020	90	443	173
Jan 2021	5	13	10
Total 2021	5	13	10
Total	4819	7372	5566