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Table of Contents
July 20, 1999; vol. 96 no. 15
Perspective
- You have accessTat as one key to HIV-induced immune pathogenesis and Pat toxoid as an important component of a vaccineRobert C. Gallo
From the Academy (free online)
- You have accessUltrafast detection and control of molecular dynamicsPhilip Anfinrud, Regina de Vivie-Riedle, and Volker Engel
- You have accessThe mathematics of microstructure and the design of new materialsK. Bhattacharya, G. Friesecke, and R. D. James
- You have accessThe past and the future fate of the universe and the formation of structure in itHans-Walter Rix
- You have accessEmerging fluorescence sensing technologies: From photophysical principles to cellular applicationsA. Prasanna de Silva, Jens Eilers, and Gregor Zlokarnik
Physical Sciences
Chemistry
- You have accessResolution of concerted versus sequential mechanisms in photo-induced double-proton transfer reaction in 7-azaindole H-bonded dimerJavier Catalán, Juan Carlos del Valle, and Michael Kasha
- You have accessGuest exchange in an encapsulation complex: A supramolecular substitution reactionJavier Santamaría, Tomás Martín, Göran Hilmersson, Stephen L. Craig, and Julius Rebek Jr.
- You have accessPotent selective nonpeptidic inhibitors of human lung tryptaseLaurence E. Burgess, Bradley J. Newhouse, Prabha Ibrahim, James Rizzi, Mohammed A. Kashem, Ann Hartman, Barbara J. Brandhuber, Clifford D. Wright, David S. Thomson, Guy P. A. Vigers, and Kevin Koch
- You have accessLong-distance charge transport in duplex DNA: The phonon-assisted polaron-like hopping mechanismPaul T. Henderson, Denise Jones, Gregory Hampikian, Yongzhi Kan, and Gary B. Schuster
Mathematics
- You have accessDynamics of Helicobacter pylori colonization in relation to the host responseMartin J. Blaser and Denise Kirschner
Physics
- You have accessA “midinfrared” scenario for cuprate superconductivity
- Inaugural Article
A. J. Leggett
Social Sciences
Anthropology
- You have accessOreopithecus was a bipedal ape after all: Evidence from the iliac cancellous architectureLorenzo Rook, Luca Bondioli, Meike Köhler, Salvador Moyà-Solà, and Roberto Macchiarelli
Biological Sciences
Agricultural Sciences
- You have accessGenetic mapping of resistance to Bacillus thuringiensis toxins in diamondback moth using biphasic linkage analysisDavid G. Heckel, Linda J. Gahan, Yong-Biao Liu, and Bruce E. Tabashnik
Biochemistry
- You have accessCrystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1Sirano Dhe-Paganon, Elizabeth A. Ottinger, Robert T. Nolte, Michael J. Eck, and Steven E. Shoelson
- You have accessA structural snapshot of an intermediate on the streptavidin–biotin dissociation pathwayStefanie Freitag, Vano Chu, Julie E. Penzotti, Lisa A. Klumb, Richard To, David Hyre, Isolde Le Trong, Terry P. Lybrand, Ronald E. Stenkamp, and Patrick S. Stayton
- You have accessInteractions of Escherichia coli σ70 within the transcription elongation complexShirley S. Daube and Peter H. von Hippel
- You have accessCrystal structure of ERA: A GTPase-dependent cell cycle regulator containing an RNA binding motifXin Chen, Donald L. Court, and Xinhua Ji
- You have accessA novel function for transglutaminase 1: Attachment of long-chain ω-hydroxyceramides to involucrin by ester bond formationZoltán Nemes, Lyuben N. Marekov, Lázló Fésüs, and Peter M. Steinert
- You have accessCrystallographic analysis of CD40 recognition and signaling by human TRAF2Sarah M. McWhirter, Steven S. Pullen, James M. Holton, James J. Crute, Marilyn R. Kehry, and Tom Alber
- You have accessA model for the mechanism of strand passage by DNA gyraseSotirios C. Kampranis, Andrew D. Bates, and Anthony Maxwell
- You have accessThree-dimensional structure of low density lipoproteins by electron cryomicroscopyElena V. Orlova, Michael B. Sherman, Wah Chiu, Hiro Mowri, Louis C. Smith, and Antonio M. Gotto Jr.
- You have accessProtein preservation and DNA retrieval from ancient tissuesHendrik N. Poinar and B. Artur Stankiewicz
- You have accessA role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylationJeffrey R. Allen, Daniel D. Clark, Jonathan G. Krum, and Scott A. Ensign
- You have accessHot-spot mutants of p53 core domain evince characteristic local structural changesKam-Bo Wong, Brian S. DeDecker, Stefan M. V. Freund, Mark R. Proctor, Mark Bycroft, and Alan R. Fersht
- You have accessCell cycle regulation of Dfp1, an activator of the Hsk1 protein kinaseGrant W. Brown and Thomas J. Kelly
- You have accessHuman papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytesJennifer T. Thomas, Walter G. Hubert, Margaret N. Ruesch, and Laimonis A. Laimins
- You have accessGene silencing via protein-mediated subcellular localization of DNASook-Kyung Kim and James C. Wang
See companion article:
- On the mechanism of silencing in Escherichia coli- Jul 20, 1999
Biophysics
- You have accessCharacterization of lipid bilayer phases by confocal microscopy and fluorescence correlation spectroscopyJonas Korlach, Petra Schwille, Watt W. Webb, and Gerald W. Feigenson
- You have accessTranslocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domainKyoung Joon Oh, Lisa Senzel, R. John Collier, and Alan Finkelstein
- You have accessMapping the sensitivity of T cells with an optical trap: Polarity and minimal number of receptors for Ca2+ signalingXunbin Wei, Bruce J. Tromberg, and Michael D. Cahalan
- You have accessA systematic study of low-resolution recognition in protein–protein complexesIlya A. Vakser, Omar G. Matar, and Chan F. Lam
Cell Biology
- You have accessDevelopment of gene-switch transgenic mice that inducibly express transforming growth factor β1 in the epidermisXiao-Jing Wang, Kristin M. Liefer, Sophia Tsai, Bert W. O’Malley, and Dennis R. Roop
- You have accessThe tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle controlLaura Sard, Paola Accornero, Silvana Tornielli, Domenico Delia, Giuseppe Bunone, Manuela Campiglio, Mario P. Colombo, Marcella Gramegna, Carlo M. Croce, Marco A. Pierotti, and Gabriella Sozzi
- You have accessRetention of the Bub3 checkpoint protein on lagging chromosomesMaria J. Martinez-Exposito, Kenneth B. Kaplan, Jay Copeland, and Peter K. Sorger
- You have accessTID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functionsJosh Syken, Tali De-Medina, and Karl Münger
- You have accessMammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progressionJoseph W. Brewer, Linda M. Hendershot, Charles J. Sherr, and J. Alan Diehl
- You have accessSuppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteinsLixin Zhang, Jing Chen, and Haian Fu
- You have accessThe cytosolic tail of class I MHC heavy chain is required for its dislocation by the human cytomegalovirus US2 and US11 gene productsCraig M. Story, Margo H. Furman, and Hidde L. Ploegh
- You have accessHsl7p, a negative regulator of Ste20p protein kinase in the Saccharomyces cerevisiae filamentous growth-signaling pathwayAtsushi Fujita, Akio Tonouchi, Takatoshi Hiroko, Fumika Inose, Takeyuki Nagashima, Rika Satoh, and Shigeko Tanaka
Developmental Biology
- You have accessGenetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammalsCheng-Kui Qu, Wen-Mei Yu, Biagio Azzarelli, and Gen-Sheng Feng
Ecology
- You have accessNatural 13C abundance reveals trophic status of fungi and host-origin of carbon in mycorrhizal fungi in mixed forestsPeter Högberg, Agneta H. Plamboeck, Andrew F. S. Taylor, and Petra M. A. Fransson
Evolution
- You have accessDivergent evolution of membrane protein topology: The Escherichia coli RnfA and RnfE homologuesAnnika Sääf, Marie Johansson, Erik Wallin, and Gunnar von Heijne
Genetics
- You have accessThe magical touch: Genome targeting in epidermal stem cells induced by tamoxifen application to mouse skinValeri Vasioukhin, Linda Degenstein, Bart Wise, and Elaine Fuchs
- You have accessGene silencing via protein-mediated subcellular localization of DNASook-Kyung Kim and James C. Wang
See companion article:
- On the mechanism of silencing in Escherichia coli- Jul 20, 1999
- You have accessMucolipidosis IV consists of one complementation groupEhud Goldin, Adele Cooney, Christine R. Kaneski, Roscoe O. Brady, and Raphael Schiffmann
- You have access“Mutagenesis” by peptide aptamers identifies genetic network members and pathway connectionsC. Ronald Geyer, Alejandro Colman-Lerner, and Roger Brent
- You have accessThirty-seven candidate genes for polycystic ovary syndrome: Strongest evidence for linkage is with follistatinMargrit Urbanek, Richard S. Legro, Deborah A. Driscoll, Ricardo Azziz, David A. Ehrmann, Robert J. Norman, Jerome F. Strauss III, Richard S. Spielman, and Andrea Dunaif
See companion article:
- You have accessAn agouti mutation lacking the basic domain induces yellow pigmentation but not obesity in transgenic miceR. J. Miltenberger, R. L. Mynatt, B. D. Bruce, W. O. Wilkison, R. P. Woychik, and E. J. Michaud
Immunology
- You have accessStromal cell-derived factor 1 (SDF-1) and antenatal human B cell lymphopoiesis: Expression of SDF-1 by mesothelial cells and biliary ductal plate epithelial cellsAurore Coulomb-L’Herminé, Ali Amara, Claudine Schiff, Ingrid Durand-Gasselin, Arnaud Foussat, Thierry Delaunay, Gérard Chaouat, Frédérique Capron, Nathalie Ledee, Pierre Galanaud, Fernando Arenzana-Seisdedos, and Dominique Emilie
- You have accessTumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12Holger N. Lode, Rong Xiang, Steven R. Duncan, Argyrios N. Theofilopoulos, Stephen D. Gillies, and Ralph A. Reisfeld
- You have accessIn vivo proliferation of naïve and memory influenza-specific CD8+ T cellsKirsten J. Flynn, Janice M. Riberdy, Jan P. Christensen, John D. Altman, and Peter C. Doherty
- You have accessCytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+ T cell responsesCynthia A. Chambers, Michael S. Kuhns, and James P. Allison
- You have accessInduction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: The IgG scaffold is important for induction and maintenance of immune hyporesponsivenessYubin Kang, Marco Melo, Edward Deng, Roland Tisch, Moustapha El-Amine, and David W. Scott
- You have accessOne Lyn molecule is sufficient to initiate phosphorylation of aggregated high-affinity IgE receptorsCarla Wofsy, Becky M. Vonakis, Henry Metzger, and Byron Goldstein
- You have accessThe lack of consensus for I-Ag7-peptide binding motifs: Is there a requirement for anchor amino acid side chains?Eugenio Carrasco-Marin, Osami Kanagawa, and Emil R. Unanue
- You have accessDipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivoChristine T. N. Pham and Timothy J. Ley
See companion article:
- You have accessCD4+ T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-γDominik Mumberg, Paul A. Monach, Sherry Wanderling, Mary Philip, Alicia Y. Toledano, Robert D. Schreiber, and Hans Schreiber
Medical Sciences
- You have accessPotent selective nonpeptidic inhibitors of human lung tryptaseLaurence E. Burgess, Bradley J. Newhouse, Prabha Ibrahim, James Rizzi, Mohammed A. Kashem, Ann Hartman, Barbara J. Brandhuber, Clifford D. Wright, David S. Thomson, Guy P. A. Vigers, and Kevin Koch
- You have accessCD8+ minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cellsDominique Bonnet, Edus H. Warren, Philip D. Greenberg, John E. Dick, and Stanley R. Riddell
- You have accessDefective CTLA-4 cycling pathway in Chediak–Higashi syndrome: A possible mechanism for deregulation of T lymphocyte activationFranck J. Barrat, Françoise Le Deist, Malika Benkerrou, Philippe Bousso, Jérome Feldmann, Alain Fischer, and Geneviève de Saint Basile
- You have accessElevated retinoic acid receptor β4 protein in human breast tumor cells with nuclear and cytoplasmic localizationKaren M. Sommer, Lucinda I. Chen, Piper M. Treuting, Lynne T. Smith, and Karen Swisshelm
- You have accessLong-term regulated expression of growth hormone in mice after intramuscular gene transferVictor M. Rivera, Xuehai Ye, Nancy L. Courage, Jeff Sachar, Frank Cerasoli Jr., James M. Wilson, and Michael Gilman
- You have accessRegulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factorKeisuke Abe, Mamoru Shoji, Jiang Chen, Angelika Bierhaus, Indrani Danave, Cornelia Micko, Katherine Casper, Dirck L. Dillehay, Peter P. Nawroth, and Frederick R. Rickles
- You have accessMedin: An integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloidBo Häggqvist, Jan Näslund, Knut Sletten, Gunilla T. Westermark, Gerd Mucchiano, Lars O. Tjernberg, Christer Nordstedt, Ulla Engström, and Per Westermark
- You have accessJE-2147: A dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1Kazuhisa Yoshimura, Ryohei Kato, Keisuke Yusa, Mark F. Kavlick, Victor Maroun, Aline Nguyen, Tsutomu Mimoto, Takamasa Ueno, Makoto Shintani, Judith Falloon, Henry Masur, Hideya Hayashi, John Erickson, and Hiroaki Mitsuya
- You have accessCpG island methylator phenotype in colorectal cancerMinoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota, James G. Herman, Stephen B. Baylin, and Jean-Pierre J. Issa
- You have accessTransient expression of DNA and RNA in parasitic helminths by using particle bombardmentRichard E. Davis, Angelica Parra, Philip T. LoVerde, Eugenia Ribeiro, Gina Glorioso, and Scott Hodgson
- You have accessA heterozygous mutation of β-actin associated with neutrophil dysfunction and recurrent infectionHiroyuki Nunoi, Tsuyoshi Yamazaki, Hiroyuki Tsuchiya, Seishi Kato, Harry L. Malech, Ichiro Matsuda, and Shiro Kanegasaki
- You have accessHerpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspasesChristian Beltinger, Simone Fulda, Thomas Kammertoens, Eric Meyer, Wolfgang Uckert, and Klaus-Michael Debatin
- You have accessNegative cross-talk between hematopoietic regulators: GATA proteins repress PU.1Pu Zhang, Gerhard Behre, Jing Pan, Atsushi Iwama, Nawarat Wara-aswapati, Hanna S. Radomska, Philip E. Auron, Daniel G. Tenen, and Zijie Sun
- You have accessCancer dormancy and cell signaling: Induction of p21waf1 initiated by membrane IgM engagement increases survival of B lymphoma cellsRadu Marches, Robert Hsueh, and Jonathan W. Uhr
Microbiology
- You have accessDynamics of Helicobacter pylori colonization in relation to the host responseMartin J. Blaser and Denise Kirschner
- You have accessA set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparumChoukri Ben Mamoun, Ilya Y. Gluzman, Sophie Goyard, Stephen M. Beverley, and Daniel E. Goldberg
Neurobiology
- You have accessDifferential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injuryUwe Scherbel, Ramesh Raghupathi, Michio Nakamura, Kathryn E. Saatman, John Q. Trojanowski, Edmund Neugebauer, Michael W. Marino, and Tracy K. McIntosh
- You have accessTransgenic mice expressing a Huntington’s disease mutation are resistant to quinolinic acid-induced striatal excitotoxicityOskar Hansson, Åsa Petersén, Marcel Leist, Pierluigi Nicotera, Roger F. Castilho, and Patrik Brundin
- You have accessInhibition of uptake unmasks rapid extracellular turnover of glutamate of nonvesicular originD. Jabaudon, K. Shimamoto, Y. Yasuda-Kamatani, M. Scanziani, B. H. Gähwiler, and U. Gerber
- You have accessNovelty acquisition is associated with induction of hippocampal long-term depressionDenise Manahan-Vaughan and Karl-Heinz Braunewell
- You have accessLithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neuronsElzbieta Chalecka-Franaszek and De-Maw Chuang
- You have accessCross-modal reorganization of callosal connectivity without altering thalamocortical projectionsSarah L. Pallas, Thomas Littman, and David R. Moore
Physiology
- You have accessIntravascular flow decreases erythrocyte consumption of nitric oxideJames C. Liao, Travis W. Hein, Mark W. Vaughn, Kuang-Tse Huang, and Lih Kuo
Plant Biology
- You have accessThe violaxanthin cycle protects plants from photooxidative damage by more than one mechanismMichel Havaux and Krishna K. Niyogi
- You have accessTargeted manipulation of maize genes in vivo using chimeric RNA/DNA oligonucleotidesTong Zhu, David J. Peterson, Laura Tagliani, Grace St. Clair, Chris L. Baszczynski, and Ben Bowen
See companion article:
- Gene therapy in plants- Jul 20, 1999
- You have accessA tool for functional plant genomics: Chimeric RNA/DNA oligonucleotides cause in vivo gene-specific mutationsPeter R. Beetham, Peter B. Kipp, Xenia L. Sawycky, Charles J. Arntzen, and Gregory D. May
See companion article:
- Gene therapy in plants- Jul 20, 1999
- You have accessLOV (light, oxygen, or voltage) domains of the blue-light photoreceptor phototropin (nph1): Binding sites for the chromophore flavin mononucleotideJohn M. Christie, Michael Salomon, Kazunari Nozue, Masamitsu Wada, and Winslow R. Briggs
- You have accessAlgae displaying the diadinoxanthin cycle also possess the violaxanthin cycleMartin Lohr and Christian Wilhelm
Psychology
- You have accessHow can we boost IQs of “dull children”?: A late adoption studyMichel Duyme, Annick-Camille Dumaret, and Stanislaw Tomkiewicz
Commentaries
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