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Table of Contents
September 11, 2001; vol. 98 no. 19
From the Academy (free online)
German-American Frontiers of Science Symposium
- You have accessGlobal climate models: Past, present, and futureMartin Stute, Amy Clement, and Gerrit Lohmann
- You have accessRandom matrices and quantum chaosThomas Kriecherbauer, Jens Marklof, and Alexander Soshnikov
Physical Sciences
Chemistry
- You have accessWater clusters: Untangling the mysteries of the liquid, one molecule at a time
- Inaugural Article
Frank N. Keutsch and Richard J. Saykally - You have accessSolvent interactions determine carbohydrate conformationKarl N. Kirschner and Robert J. Woods
- You have accessDominant/recessive behavior in the expression of molecular information: Self-assembly of inorganic macrocyclic architectures containing coordinatively unsaturated ligandsDaniel P. Funeriu, Kari Rissanen, and Jean-Marie P. Lehn
Geology
- You have accessPronounced climatic variations in Alaska during the last two millennia
- From the Cover
Feng Sheng Hu, Emi Ito, Thomas A. Brown, B. Brandon Curry, and Daniel R. Engstrom
Statistics
Social Sciences
Anthropology
- You have accessStone tool function at the paleolithic sites of Starosele and Buran Kaya III, Crimea: Behavioral implicationsBruce L. Hardy, Marvin Kay, Anthony E. Marks, and Katherine Monigal
Biological Sciences
Biochemistry
- You have accessBiosynthesis of a fluorescent cyanobacterial C-phycocyanin holo-α subunit in a heterologous hostAaron J. Tooley, Yuping A. Cai, and Alexander N. Glazer
- You have accessGenetic engineering of phytochrome biosynthesis in bacteriaGregory A. Gambetta and J. Clark Lagarias
- You have accessCloning and characterization of a histone deacetylase, HDAC9Xianbo Zhou, Paul A. Marks, Richard A. Rifkind, and Victoria M. Richon
- You have accessIn vivo mechanism-based inactivation of S-adenosylmethionine decarboxylases from Escherichia coli, Salmonella typhimurium, and SaccharomycescerevisiaeYong-Fu Li, Sonja Hess, Lewis K. Pannell, Celia White Tabor, and Herbert Tabor
- You have accessOverlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysisJulia M. Flynn, Igor Levchenko, Meredith Seidel, Sue H. Wickner, Robert T. Sauer, and Tania A. Baker
- You have accessInhibition of transcription factor-DNA complexes and gene expression by a microgonotropenChristine M. White, Alexander L. Satz, Thomas C. Bruice, and Terry A. Beerman
- You have accessSearching sequence space for protein catalystsSean V. Taylor, Kai U. Walter, Peter Kast, and Donald Hilvert
- You have accessStructural features of an influenza virus promoter and their implications for viral RNA synthesisSung-Hun Bae, Hae-Kap Cheong, Joon-Hwa Lee, Chaejoon Cheong, Masatsune Kainosho, and Byong-Seok Choi
- You have accessHuman mitochondrial topoisomerase IHongliang Zhang, Juana M. Barceló, Benson Lee, Glenda Kohlhagen, Drazen B. Zimonjic, Nicholas C. Popescu, and Yves Pommier
- You have accessBiosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinisCameron Jennings, Jenny West, Clement Waine, David Craik, and Marilyn Anderson
- You have accessEffect of spermidine on the in vivo degradation of ornithine decarboxylase in Saccharomyces cerevisiaeRashmi Gupta, Nobuko Hamasaki-Katagiri, Celia White Tabor, and Herbert Tabor
- You have accessA chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactionsJeffrey R. Peterson, R. Scott Lokey, Timothy J. Mitchison, and Marc W. Kirschner
- You have accessGenomic profiling of short- and long-term caloric restriction effects in the liver of aging miceShelley X. Cao, Joseph M. Dhahbi, Patricia L. Mote, and Stephen R. Spindler
Biophysics
- You have accessProtein docking along smooth association pathwaysCarlos J. Camacho and Sandor Vajda
- You have accessPartitioning of Thy-1, GM1, and cross-linked phospholipid analogs into lipid rafts reconstituted in supported model membrane monolayers
- From the Cover
Christian Dietrich, Zoya N. Volovyk, Moshe Levi, Nancy L. Thompson, and Ken JacobsonSee companion article:
- You have accessMultiwavelength anomalous diffraction analysis at the M absorption edges of uraniumYee Liu, Craig M. Ogata, and Wayne A. Hendrickson
- You have accessFunctionalized xenon as a biosensorMegan M. Spence, Seth M. Rubin, Ivan E. Dimitrov, E. Janette Ruiz, David E. Wemmer, Alexander Pines, Shao Qin Yao, Feng Tian, and Peter G. Schultz
- You have accessCompaction of single DNA molecules induced by binding of integration host factor (IHF)B. M. Jaffar Ali, Roee Amit, Ido Braslavsky, Amos B. Oppenheim, Opher Gileadi, and Joel Stavans
- You have accessHistory dependence of protein adsorption kineticsClaudio Calonder, Yanrong Tie, and Paul R. Van Tassel
- You have accessHydration of the peptide backbone largely defines the thermodynamic propensity scale of residues at the C′ position of the C-capping box of α-helicesSusan T. Thomas, Vakhtang V. Loladze, and George I. Makhatadze
- You have accessThe plug domain of FepA, a TonB-dependent transport protein from Escherichia coli, binds its siderophore in the absence of the transmembrane barrel domainKen C. Usher, Engin Özkan, Kevin H. Gardner, and Johann Deisenhofer
- You have accessMultiple conformations of PEVK proteins detected by single-molecule techniquesHongbin Li, Andres F. Oberhauser, Sambra D. Redick, Mariano Carrion-Vazquez, Harold P. Erickson, and Julio M. Fernandez
- You have accessConversion of monomeric protein L to an obligate dimer by computational protein designBrian Kuhlman, Jason W. O'Neill, David E. Kim, Kam Y. J. Zhang, and David Baker
Cell Biology
- You have accessRegulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoformX.-Z. Shawn Xu, Fabian Moebius, Donald L. Gill, and Craig Montell
- You have accessA model for melanosome biogenesis based on the purification and analysis of early melanosomesTsuneto Kushimoto, Venkatesha Basrur, Julio Valencia, Jun Matsunaga, Wilfred D. Vieira, Victor J. Ferrans, Jacqueline Muller, Ettore Appella, and Vincent J. Hearing
- You have accessStructure of the Sec23p/24p and Sec13p/31p complexes of COPIIGerardo Z. Lederkremer, Yifan Cheng, Benjamin M. Petre, Erik Vogan, Sebastian Springer, Randy Schekman, Thomas Walz, and Tomas Kirchhausen
- You have accessImmunolocalization of UDP-glucose:glycoprotein glucosyltransferase indicates involvement of pre-Golgi intermediates in protein quality controlChristian Zuber, Jing-yu Fan, Bruno Guhl, Armando Parodi, John H. Fessler, Carol Parker, and Jürgen Roth
- You have accessHematopoietic colony-forming cells derived from human embryonic stem cellsDan S. Kaufman, Eric T. Hanson, Rachel L. Lewis, Robert Auerbach, and James A. Thomson
- You have accessSuppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinaseKyle A. Furge, David Kiewlich, Phuong Le, My Nga Vo, Michel Faure, Anthony R. Howlett, Kenneth E. Lipson, George F. Vande Woude, and Craig P. Webb
Developmental Biology
- You have accessRhesus monkey placental transgene expression after lentiviral gene transfer into preimplantation embryosM. J. Wolfgang, S. G. Eisele, M. A. Browne, M. L. Schotzko, M. A. Garthwaite, M. Durning, A. Ramezani, R. G. Hawley, J. A. Thomson, and T. G. Golos
- You have accessCardiomyocytes induce endothelial cells to trans-differentiate into cardiac muscle: Implications for myocardium regeneration
- From the Cover
G. Condorelli, U. Borello, L. De Angelis, M. Latronico, D. Sirabella, M. Coletta, R. Galli, G. Balconi, A. Follenzi, G. Frati, M. G. Cusella De Angelis, L. Gioglio, S. Amuchastegui, L. Adorini, L. Naldini, A. Vescovi, E. Dejana, and G. Cossu - You have accessDiverse developmental programs of Xenopus laevis metamorphosis are inhibited by a dominant negative thyroid hormone receptorAlexander M. Schreiber, Biswajit Das, Haochu Huang, Nicholas Marsh-Armstrong, and Donald D. Brown
Evolution
- You have accessLateral transfer at the gene and subgenic levels in the evolution of eukaryotic enolasePatrick J. Keeling and Jeffrey D. Palmer
- You have accessIncomplete taxon sampling is not a problem for phylogenetic inferenceMichael S. Rosenberg and Sudhir Kumar
- You have accessReceptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinasesShin-Han Shiu and Anthony B. Bleecker
- You have accessWhen genetic distance matters: Measuring genetic differentiation at microsatellite loci in whole-genome scans of recent and incipient mosquito speciesRui Wang, Liangbiao Zheng, Yeya T. Touré, Thomas Dandekar, and Fotis C. Kafatos
Genetics
- You have accessTetracycline-inducible systems for DrosophilaMichael J. Stebbins, Stefanie Urlinger, Gerry Byrne, Bruno Bello, Wolfgang Hillen, and Jerry C. P. Yin
- You have accessCorrespondence analysis applied to microarray dataKurt Fellenberg, Nicole C. Hauser, Benedikt Brors, Albert Neutzner, Jörg D. Hoheisel, and Martin Vingron
- You have accessChemosensitivity prediction by transcriptional profilingJane E. Staunton, Donna K. Slonim, Hilary A. Coller, Pablo Tamayo, Michael J. Angelo, Johnny Park, Uwe Scherf, Jae K. Lee, William O. Reinhold, John N. Weinstein, Jill P. Mesirov, Eric S. Lander, and Todd R. Golub
- You have accessIdentification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of miceAnny Fortin, Lon R. Cardon, Mifong Tam, Emil Skamene, Mary M. Stevenson, and Philippe Gros
Immunology
- You have accessCrystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC moleculeJia-huai Wang, Rob Meijers, Yi Xiong, Jin-huan Liu, Toshiko Sakihama, Rongguang Zhang, Andrzej Joachimiak, and Ellis L. Reinherz
- You have accessSingle-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivoTraci Zell, Alexander Khoruts, Elizabeth Ingulli, Jody L. Bonnevier, Daniel L. Mueller, and Marc K. Jenkins
- You have accessCD40 stimulation accelerates deletion of tumor-specific CD8+ T cells in the absence of tumor-antigen vaccinationRoss M. Kedl, Michael Jordan, Terence Potter, John Kappler, Philippa Marrack, and Steven Dow
- You have accessInduction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccineRuobing Wang, Judith Epstein, Fe Maria Baraceros, Edward J. Gorak, Yupin Charoenvit, Daniel J. Carucci, Richard C. Hedstrom, Nancy Rahardjo, Tanya Gay, Peter Hobart, Rick Stout, Trevor R. Jones, Thomas L. Richie, Suezanne E. Parker, Denise L. Doolan, Jon Norman, and Stephen L. Hoffman
Medical Sciences
- You have accessProstatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epitheliumMichael Stanbrough, Irwin Leav, Paul W. L. Kwan, Glenn J. Bubley, and Steven P. Balk
- You have accessImmune mimicry in malaria: Plasmodium falciparum secretes a functional histamine-releasing factor homolog in vitro and in vivoSusan M. MacDonald, Jamaree Bhisutthibhan, Theresa A. Shapiro, Stephen J. Rogerson, Terrie E. Taylor, Madalitso Tembo, Jacqueline M. Langdon, and Steven R. Meshnick
- You have accessThe histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen speciesAstrid A. Ruefli, Michael J. Ausserlechner, David Bernhard, Vivien R. Sutton, Kellie M. Tainton, Reinhard Kofler, Mark J. Smyth, and Ricky W. Johnstone
- You have accessInvestigating stem cells in human colon by using methylation patterns
- From the Cover
Yasushi Yatabe, Simon Tavaré, and Darryl ShibataSee companion article:
- You have accessNitric oxide-induced apoptosis in pancreatic β cells is mediated by the endoplasmic reticulum stress pathwaySeiichi Oyadomari, Kiyoshi Takeda, Masaki Takiguchi, Tomomi Gotoh, Makoto Matsumoto, Ikuo Wada, Shizuo Akira, Eiichi Araki, and Masataka Mori
- You have accessOligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumorsQ. Richard Lu, John K. Park, Elizabeth Noll, Jennifer A. Chan, John Alberta, Dongin Yuk, M. Garcia Alzamora, David N. Louis, Charles D. Stiles, David H. Rowitch, and Peter M. Black
- You have accessInhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemiasSergio Dias, Koichi Hattori, Beate Heissig, Zhenping Zhu, Yan Wu, Larry Witte, Daniel J. Hicklin, Masatoshi Tateno, Peter Bohlen, Malcolm A. S. Moore, and Shahin Rafii
- You have accessLoss of presenilin 1 is associated with enhanced β-catenin signaling and skin tumorigenesisXuefeng Xia, Su Qian, Salvador Soriano, Ying Wu, Anthony M. Fletcher, Xiao-Jing Wang, Edward H. Koo, Xiangwei Wu, and Hui Zheng
See companion article:
- You have accessGene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsTherese Sørlie, Charles M. Perou, Robert Tibshirani, Turid Aas, Stephanie Geisler, Hilde Johnsen, Trevor Hastie, Michael B. Eisen, Matt van de Rijn, Stefanie S. Jeffrey, Thor Thorsen, Hanne Quist, John C. Matese, Patrick O. Brown, David Botstein, Per Eystein Lønning, and Anne-Lise Børresen-Dale
Microbiology
- You have accessModulation of HIV-like particle assembly in vitro by inositol phosphatesStephen Campbell, Robert J. Fisher, Eric M. Towler, Stephen Fox, Haleem J. Issaq, Tracy Wolfe, Lawrence R. Phillips, and Alan Rein
- You have accessA role for IL-1α in inducing pathologic inflammation during bacterial infectionPeter H. Dube, Paula A. Revell, David D. Chaplin, Robin G. Lorenz, and Virginia L. Miller
- You have accessAn acquired and a native penicillin-binding protein cooperate in building the cell wall of drug-resistant staphylococciMariana G. Pinho, Hermínia de Lencastre, and Alexander Tomasz
- You have accessA simple model host for identifying Gram-positive virulence factorsDanielle A. Garsin, Costi D. Sifri, Eleftherios Mylonakis, Xiang Qin, Kavindra V. Singh, Barbara E. Murray, Stephen B. Calderwood, and Frederick M. Ausubel
- You have accessReplication of enhancer-deficient amphotropic murine leukemia virus in human cellsFrank U. Reuss, Bianca Berdel, Martin Ploss, and Ricarda Heber
Neurobiology
- You have accessLocalized cerebral blood flow response at submillimeter columnar resolutionTimothy Q. Duong, Dae-Shik Kim, Kâmil Uğurbil, and Seong-Gi Kim
- You have accessAdult-generated hippocampal and neocortical neurons in macaques have a transient existence
- Inaugural Article
E. Gould, N. Vail, M. Wagers, and C. G. Gross - You have accessAn AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's diseaseHideki Mochizuki, Hideki Hayakawa, Makoto Migita, Mamoru Shibata, Ryota Tanaka, Asuka Suzuki, Yumi Shimo-Nakanishi, Takao Urabe, Masanori Yamada, Kenji Tamayose, Takashi Shimada, Masayuki Miura, and Yoshikuni Mizuno
- You have accessHeterosynaptic metaplasticity in the hippocampus in vivo: A BCM-like modifiable threshold for LTPWickliffe C. Abraham, Sara E. Mason-Parker, Mark F. Bear, Sarah Webb, and Warren P. Tate
- You have accessA src family tyrosine kinase inhibits neurotransmitter release from neuronal cellsHiroshi Ohnishi, Saori Yamamori, Kanako Ono, Kyota Aoyagi, Shunzo Kondo, and Masami Takahashi
Pharmacology
- You have accessDistinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREBBernhard M. Mayr, Gianluca Canettieri, and Marc R. Montminy
- You have accessQuinine blocks specific gap junction channel subtypesMiduturu Srinivas, Matthew G. Hopperstad, and David C. Spray
Physiology
- You have accessLocal uncaging of caged Ca2+ reveals distribution of Ca2+-activated Cl− channels in pancreatic acinar cellsMyoung Kyu Park, Richard B. Lomax, Alexei V. Tepikin, and Ole H. Petersen
Plant Biology
- You have accessPlant gene expression response to Agrobacterium tumefaciensRenata F. Ditt, Eugene W. Nester, and Luca Comai
- You have accessTwo types of MGDG synthase genes, found widely in both 16:3 and 18:3 plants, differentially mediate galactolipid syntheses in photosynthetic and nonphotosynthetic tissues in Arabidopsis thalianaKoichiro Awai, Eric Maréchal, Maryse A. Block, Delphine Brun, Tatsuru Masuda, Hiroshi Shimada, Ken-ichiro Takamiya, Hiroyuki Ohta, and Jacques Joyard
Psychology
- You have accessPrediction of cognitive decline in normal elderly subjects with 2-[18F]fluoro-2-deoxy-d-glucose/positron-emission tomography (FDG/PET)M. J. de Leon, A. Convit, O. T. Wolf, C. Y. Tarshish, S. DeSanti, H. Rusinek, W. Tsui, E. Kandil, A. J. Scherer, A. Roche, A. Imossi, E. Thorn, M. Bobinski, C. Caraos, P. Lesbre, D. Schlyer, J. Poirier, B. Reisberg, and J. Fowler
Commentaries
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