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Table of Contents
January 22, 2002; vol. 99 no. 2
Physical Sciences
Chemistry
- You have accessA stochastic algorithm for global optimization and for best populations: A test case of side chains in proteinsMeir Glick, Anwar Rayan, and Amiram Goldblum
Geophysics
- You have accessRedefinition of the mode Grüneisen parameter for polyatomic substances and thermodynamic implicationsAnne M. Hofmeister and Ho-kwang Mao
Mathematics
Biological Sciences
Applied Biological Sciences
- You have accessTumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasisDongfang Liu, Zachary Shriver, Ganesh Venkataraman, Yosuf El Shabrawi, and Ram Sasisekharan
See companion article:
- You have accessHigh throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessorBrian M. Paegel, Charles A. Emrich, Gary J. Wedemayer, James R. Scherer, and Richard A. Mathies
Biochemistry
- You have accessAbietadiene synthase catalysis: Mutational analysis of a prenyl diphosphate ionization-initiated cyclization and rearrangementReuben J. Peters and Rodney B. Croteau
- You have accessBlocking site-to-site translocation of a misactivated amino acid by mutation of a class I tRNA synthetaseAnthony C. Bishop, Tyzoon K. Nomanbhoy, and Paul Schimmel
- You have accessSnapshot of a key intermediate in enzymatic thiamin catalysis: Crystal structure of the α-carbanion of (α,β-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae
- From the Cover
Erik Fiedler, Stina Thorell, Tatyana Sandalova, Ralph Golbik, Stephan König, and Gunter Schneider - You have accessArchaeal dUTPase enhances PCR amplifications with archaeal DNA polymerases by preventing dUTP incorporationHolly H. Hogrefe, Connie J. Hansen, Bradley R. Scott, and Kirk B. Nielson
- You have accessMultiple hematopoietic defects and delayed globin switching in Ikaros null miceRocio A. Lopez, Stuti Schoetz, Kathryn DeAngelis, David O'Neill, and Arthur Bank
- You have accessProtein and ligand dynamics in 4-hydroxybenzoate hydroxylaseJian Wang, Mariliz Ortiz-Maldonado, Barrie Entsch, Vincent Massey, David Ballou, and Domenico L. Gatti
- You have accessCombinatorial approaches: A new tool to search for highly structured β-hairpin peptidesMaria Teresa Pastor, Manuela López de la Paz, Emmanuel Lacroix, Luis Serrano, and Enrique Pérez-Payá
- You have accessGene characterized for membrane desaturase that produces (E)-11 isomers of mono- and diunsaturated fatty acidsWeitian Liu, Hongmei Jiao, Nancy C. Murray, Marion O'Connor, and Wendell L. Roelofs
- You have accessA mutation in the peroxisome proliferator-activated receptor γ-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in miceYael Olswang, Hannah Cohen, Orit Papo, Hanoch Cassuto, Colleen M. Croniger, Parvin Hakimi, Shirley M. Tilghman, Richard W. Hanson, and Lea Reshef
- You have accessHerpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymesRyan Hagglund, Charles Van Sant, Pascal Lopez, and Bernard Roizman
- You have accessmda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive propertiesDong-chul Kang, Rahul V. Gopalkrishnan, Qingping Wu, Eckhard Jankowsky, Anna Marie Pyle, and Paul B. Fisher
- You have accessActivation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptidesLidija Covic, Amy L. Gresser, Joyce Talavera, Steven Swift, and Athan Kuliopulos
- You have accessTranscription-coupled repair in RNA polymerase I-transcribed genes of yeastAntonio Conconi, Vyacheslav A. Bespalov, and Michael J. Smerdon
- You have accesstRNA elements mediate the assembly of an icosahedral RNA virusYoon Gi Choi, Theo W. Dreher, and A. L. N. Rao
- You have accessSupervillin associates with androgen receptor and modulates its transcriptional activityHuei-Ju Ting, Shuyuan Yeh, Kazuo Nishimura, and Chawnshang Chang
Biophysics
- You have accessSelf-assembly properties of a model RING domain
- From the Cover
Alex Kentsis, Ronald E. Gordon, and Katherine L. B. Borden - You have accessRobustness of circadian rhythms with respect to molecular noiseDidier Gonze, José Halloy, and Albert Goldbeter
- You have accessSynchronizing genetic relaxation oscillators by intercell signalingDavid McMillen, Nancy Kopell, Jeff Hasty, and J. J. Collins
- You have accessProtein folding mediated by solvation: Water expulsion and formation of the hydrophobic core occur after the structural collapseMargaret S. Cheung, Angel E. García, and José N. Onuchic
- You have accessImproved recognition of native-like protein structures using a family of designed sequencesPatrice Koehl and Michael Levitt
- You have accessFunction of the voltage gate of gap junction channels: Selective exclusion of moleculesYang Qu and Gerhard Dahl
- You have accessA stochastic algorithm for global optimization and for best populations: A test case of side chains in proteinsMeir Glick, Anwar Rayan, and Amiram Goldblum
- You have accessReal-time and equilibrium 19F-NMR studies reveal the role of domain–domain interactions in the folding of the chaperone PapDJames G. Bann, Jerome Pinkner, Scott J. Hultgren, and Carl Frieden
Cell Biology
- You have accessReactive oxygen generated by Nox1 triggers the angiogenic switchJack L. Arbiser, John Petros, Robert Klafter, Baskaran Govindajaran, Elizabeth R. McLaughlin, Lawrence F. Brown, Cynthia Cohen, Marsha Moses, Susan Kilroy, Rebecca S. Arnold, and J. David Lambeth
- You have accessCharacterization of protein kinase C β isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularizationKiyoshi Suzuma, Noriko Takahara, Izumi Suzuma, Keiji Isshiki, Kohjiro Ueki, Michael Leitges, Lloyd Paul Aiello, and George L. King
- You have accessRequirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragmentPaul J. Muchowski, Ke Ning, Crislyn D'Souza-Schorey, and Stanley Fields
- You have accessTensin1 and a previously undocumented family member, tensin2, positively regulate cell migrationHuaiyang Chen, Ian C. Duncan, Hormozd Bozorgchami, and Su Hao Lo
- You have accessActivity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentrationJoan D. Ferraris, Chester K. Williams, Prita Persaud, Zheng Zhang, Ye Chen, and Maurice B. Burg
- You have accessBudding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasomeMinoru Funakoshi, Toru Sasaki, Takeharu Nishimoto, and Hideki Kobayashi
Developmental Biology
- You have accessExploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genomeBenjamin P. Berman, Yutaka Nibu, Barret D. Pfeiffer, Pavel Tomancak, Susan E. Celniker, Michael Levine, Gerald M. Rubin, and Michael B. Eisen
See companion article:
- You have accessGenome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryoMichele Markstein, Peter Markstein, Vicky Markstein, and Michael S. Levine
See companion article:
- You have accessEvolution of germ-line signals that regulate growth and aging in nematodesMavji N. Patel, Christopher G. Knight, Constantina Karageorgi, and Armand M. Leroi
- You have accessAPH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryosCaroline Goutte, Makoto Tsunozaki, Valerie A. Hale, and James R. Priess
- You have accessGenomic structure and functional control of the Dlx3-7 bigene clusterKenta Sumiyama, Steven Q. Irvine, David W. Stock, Kenneth M. Weiss, Kazuhiko Kawasaki, Nobuyoshi Shimizu, Cooduvalli S. Shashikant, Webb Miller, and Frank H. Ruddle
Ecology
- You have accessChemical warfare between microbes promotes biodiversityTamás L. Czárán, Rolf F. Hoekstra, and Ludo Pagie
See companion article:
- Chemical warfare from an ecological perspective- Jan 22, 2002
- You have accessGolden eagles, feral pigs, and insular carnivores: How exotic species turn native predators into prey
- From the Cover
Gary W. Roemer, C. Josh Donlan, and Franck CourchampSee companion article:
Evolution
- You have accessIn silico chromosome staining: Reconstruction of Giemsa bands from the whole human genome sequenceYoshihito Niimura and Takashi Gojobori
- You have accessRecombinatoric exploration of novel folded structures: A heteropolymer-based model of protein evolutionary landscapesYan Cui, Wing Hung Wong, Erich Bornberg-Bauer, and Hue Sun Chan
Genetics
- You have accessExploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genomeBenjamin P. Berman, Yutaka Nibu, Barret D. Pfeiffer, Pavel Tomancak, Susan E. Celniker, Michael Levine, Gerald M. Rubin, and Michael B. Eisen
See companion article:
- You have accessMolecular analysis of mutations in DNA polymerase η in xeroderma pigmentosum-variant patientsBernard C. Broughton, Agnes Cordonnier, Wim J. Kleijer, Nicolaas G. J. Jaspers, Heather Fawcett, Anja Raams, Victor H. Garritsen, Anne Stary, Marie-Françoise Avril, François Boudsocq, Chikahide Masutani, Fumio Hanaoka, Robert P. Fuchs, Alain Sarasin, and Alan R. Lehmann
- You have accessDefective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1αDavid D. Kline, Ying-Jie Peng, Dominador J. Manalo, Gregg L. Semenza, and Nanduri R. Prabhakar
- You have accessEvaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium
- From the Cover
Deborah Thompson, Csilla I. Szabo, Jon Mangion, Rogier A. Oldenburg, Fabrice Odefrey, Sheila Seal, Rita Barfoot, Karin Kroeze-Jansema, Dawn Teare, Nazneen Rahman, Hélène Renard, KConFab Consortiumef, Graham Mann, John L. Hopper, Saundra S. Buys, Irene L. Andrulis, Ruby Senie, Mary B. Daly, Dee West, Elaine A. Ostrander, Ken Offit, Tamar Peretz, Ana Osorio, J. Benitez, Katherine L. Nathanson, Olga M. Sinilnikova, Edith Olàh, Yves-Jean Bignon, Pablo Ruiz, Michael D. Badzioch, Hans F. A. Vasen, Andrew P. Futreal, Catherine M. Phelan, Steven A. Narod, Henry T. Lynch, Bruce A. J. Ponder, Ros A. Eeles, Hanne Meijers-Heijboer, Dominique Stoppa-Lyonnet, Fergus J. Couch, Diana M. Eccles, D. Gareth Evans, Jenny Chang-Claude, Gilbert Lenoir, Barbara L. Weber, Peter Devilee, Douglas F. Easton, David E. Goldgar, and Michael R. Stratton - You have accessKu86 is essential in human somatic cellsGang Li, Caron Nelsen, and Eric A. Hendrickson
- You have accessLife extension in Drosophila by feeding a drugHyung-Lyun Kang, Seymour Benzer, and Kyung-Tai Min
- You have accessFunctional annotation of mammalian genomic DNA sequence by chemical mutagenesis: A fine-structure genetic mutation map of a 1- to 2-cM segment of mouse chromosome 7 corresponding to human chromosome 11p14-p15Eugene M. Rinchik, Donald A. Carpenter, and Dabney K. Johnson
- You have accessPhysical and genetic mapping of barley (Hordeum vulgare) germin-like cDNAsArnis Druka, David Kudrna, C. Gamini Kannangara, Diter von Wettstein, and Andris Kleinhofs
- You have accessAssociation of human aging with a functional variant of klothoDan E. Arking, Alice Krebsova, Milan Macek Sr., Milan Macek Jr., Albert Arking, I. Saira Mian, Linda Fried, Ada Hamosh, Srabani Dey, Iain McIntosh, and Harry C. Dietz
- You have accessEvidence for positive selection and population structure at the human MAO-A geneYoav Gilad, Shai Rosenberg, Molly Przeworski, Doron Lancet, and Karl Skorecki
Immunology
- You have accessImplications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formationRussell E. Vance, Amanda M. Jamieson, Dragana Cado, and David H. Raulet
- You have accessGrafts of supplementary thymuses injected with allogeneic pancreatic islets protect nonobese diabetic mice against diabetesJ. Salaün, N. Simmenauer, P. Belo, A. Coutinho, and N. M. Le Douarin
- You have accessImpaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic miceY. Zhang, S. F. Schlossman, R. A. Edwards, Ching-Nan Ou, J. Gu, and Mei X. Wu
- You have accessDifferential role of SLP-76 domains in T cell development and functionLalit Kumar, Vadim Pivniouk, Miguel A. de la Fuente, Dhafer Laouini, and Raif S. Geha
Medical Sciences
- You have accessPlasminogen activator inhibitor-1 is a major stress-regulated gene: Implications for stress-induced thrombosis in aged individualsKoji Yamamoto, Kyosuke Takeshita, Takayoshi Shimokawa, Hong Yi, Ken-ichi Isobe, David J. Loskutoff, and Hidehiko Saito
- You have accessHeat shock protein 90 catalyzes activation of the prekallikrein-kininogen complex in the absence of factor XIIKusumam Joseph, Baby G. Tholanikunnel, and Allen P. Kaplan
- You have accessRescue of hereditary form of dilated cardiomyopathy by rAAV-mediated somatic gene therapy: Amelioration of morphological findings, sarcolemmal permeability, cardiac performances, and the prognosis of TO-2 hamstersTomie Kawada, Mikio Nakazawa, Sakura Nakauchi, Ken Yamazaki, Ryoichi Shimamoto, Masashi Urabe, Jumi Nakata, Chieko Hemmi, Fujiko Masui, Toshiaki Nakajima, Jun-Ichi Suzuki, John Monahan, Hiroshi Sato, Tomoh Masaki, Keiya Ozawa, and Teruhiko Toyo-oka
- You have accessActivated glycogen synthase-3β suppresses cardiac hypertrophy in vivoChristopher L. Antos, Timothy A. McKinsey, Norbert Frey, William Kutschke, John McAnally, John M. Shelton, James A. Richardson, Joseph A. Hill, and Eric N. Olson
- You have accessCa2+-desensitizing effect of a deletion mutation ΔK210 in cardiac troponin T that causes familial dilated cardiomyopathyS. Morimoto, Q.-W. Lu, K. Harada, F. Takahashi-Yanaga, R. Minakami, M. Ohta, T. Sasaguri, and I. Ohtsuki
- You have accessLymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cellsMarco Prinz, Fabio Montrasio, Michael A. Klein, Petra Schwarz, Josef Priller, Bernhard Odermatt, Klaus Pfeffer, and Adriano Aguzzi
- You have accessMissense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancerShaun P. Scott, Regina Bendix, Philip Chen, Raymond Clark, Thilo Dörk, and Martin F. Lavin
- You have accessTumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recoveryW. Asavaroengchai, Y. Kotera, and J. J. Mulé
- You have accessA peptide that binds and stabilizes p53 core domain: Chaperone strategy for rescue of oncogenic mutantsAssaf Friedler, Lars O. Hansson, Dmitry B. Veprintsev, Stefan M. V. Freund, Thomas M. Rippin, Penka V. Nikolova, Mark R. Proctor, Stefan Rüdiger, and Alan R. Fersht
- You have accessPolycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1)Donald Metcalf, Sandra Mifsud, Ladina Di Rago, Nicos A. Nicola, Douglas J. Hilton, and Warren S. Alexander
- You have accessTumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGEFranky Van Herreweghe, Jianqiang Mao, Frank W. R. Chaplen, Johan Grooten, Kris Gevaert, Joël Vandekerckhove, and Katia Vancompernolle
- You have accessOverexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain functionDimiter G. Demirov, Akira Ono, Jan M. Orenstein, and Eric O. Freed
- You have accessChanges in subcellular distribution of pituitary receptors for luteinizing hormone-releasing hormone (LH-RH) after treatment with the LH-RH antagonist cetrorelixGabor Halmos and Andrew V. Schally
Microbiology
- You have accessA genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzaeBrian J. Akerley, Eric J. Rubin, Veronica L. Novick, Kensey Amaya, Nicholas Judson, and John J. Mekalanos
- You have accessStereotyped and specific gene expression programs in human innate immune responses to bacteriaJennifer C. Boldrick, Ash A. Alizadeh, Maximilian Diehn, Sandrine Dudoit, Chih Long Liu, Christopher E. Belcher, David Botstein, Louis M. Staudt, Patrick O. Brown, and David A. Relman
- You have accessSpontaneous molecular reactivation of herpes simplex virus type 1 latency in miceLawrence T. Feldman, Aaron R. Ellison, Cynthia C. Voytek, Li Yang, Philip Krause, and Todd P. Margolis
- You have accessGenome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilumSorel T. Fitz-Gibbon, Heidi Ladner, Ung-Jin Kim, Karl O. Stetter, Melvin I. Simon, and Jeffrey H. Miller
- You have accessFour plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidineRitu Banerjee, Jun Liu, Wandy Beatty, Lorraine Pelosof, Michael Klemba, and Daniel E. Goldberg
- You have accessComplete genome sequence of Clostridium perfringens, an anaerobic flesh-eaterTohru Shimizu, Kaori Ohtani, Hideki Hirakawa, Kenshiro Ohshima, Atsushi Yamashita, Tadayoshi Shiba, Naotake Ogasawara, Masahira Hattori, Satoru Kuhara, and Hideo Hayashi
Neurobiology
- You have accessEffects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicityAli Khoshnan, Jan Ko, and Paul H. Patterson
- You have accessRole of a locus control region in the mutually exclusive expression of human red and green cone pigment genesPhilip M. Smallwood, Yanshu Wang, and Jeremy Nathans
- You have accessSynaptophysin regulates activity-dependent synapse formation in cultured hippocampal neuronsLeila Tarsa and Yukiko Goda
- You have accessExperience-dependent changes in cerebellar contributions to motor sequence learningJulien Doyon, Allen W. Song, Avi Karni, François Lalonde, Michelle M. Adams, and Leslie G. Ungerleider
- You have accessCostimulation of N-methyl-d-aspartate and muscarinic neuronal receptors modulates gap junctional communication in striatal astrocytesN. Rouach, M. Tencé, J. Glowinski, and C. Giaume
- You have accessThe NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenalineLuc Jasmin, Duc Tien, David Weinshenker, Richard D. Palmiter, Paul G. Green, Gabriella Janni, and Peter T. Ohara
See companion article:
- You have accessElimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domainMats H. Holmqvist, Jie Cao, Ricardo Hernandez-Pineda, Michael D. Jacobson, Karen I. Carroll, M. Amy Sung, Maria Betty, Pei Ge, Kevin J. Gilbride, Melissa E. Brown, Mark E. Jurman, Deborah Lawson, Inmaculada Silos-Santiago, Yu Xie, Manuel Covarrubias, Kenneth J. Rhodes, Peter S. Distefano, and W. Frank An
- You have accessExperience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortexJohn J. Renger, Kenichi N. Hartman, Yoshiko Tsuchimoto, Mineto Yokoi, Shigetada Nakanishi, and Takao K. Hensch
Pharmacology
- You have accessInsulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycinTodd A. Huffman, Isabelle Mothe-Satney, and John C. Lawrence Jr.
Physiology
- You have accessAnti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptorCarmen Martinez, Catalina Abad, Mario Delgado, Alicia Arranz, Maria G. Juarranz, Nieves Rodriguez-Henche, Philippe Brabet, Javier Leceta, and Rosa P. Gomariz
- You have accessDecreased pulmonary vascular permeability in aquaporin-1-null humansLandon S. King, Søren Nielsen, Peter Agre, and Robert H. Brown
Plant Biology
- You have accessThe tomato Blind gene encodes a MYB transcription factor that controls the formation of lateral meristemsGregor Schmitz, Edith Tillmann, Filomena Carriero, Carola Fiore, Francesco Cellini, and Klaus Theres
- You have accessDirected molecular evolution of ADP-glucose pyrophosphorylasePeter R. Salamone, I. Halil Kavakli, Casey J. Slattery, and Thomas W. Okita
- You have accessSuppressors of transcriptional transgenic silencing in Chlamydomonas are sensitive to DNA-damaging agents and reactivate transposable elements
- From the Cover
Byeong-ryool Jeong, Dancia Wu-Scharf, Chaomei Zhang, and Heriberto Cerutti - You have accessRecombination rates between adjacent genic and retrotransposon regions in maize vary by 2 orders of magnitudeHuihua Fu, Zhenwei Zheng, and Hugo K. Dooner
See companion article:
- Finding the crosswalks on DNA- Apr 30, 2002
- You have accessImpact of folivory on photosynthesis is greater than the sum of its holesA. R. Zangerl, J. G. Hamilton, T. J. Miller, A. R. Crofts, K. Oxborough, M. R. Berenbaum, and E. H. de Lucia
- You have accessEvaluation of transgenic tomato plants expressing an additional phytoene synthase in a fruit-specific mannerPaul D. Fraser, Susanne Romer, Cathie A. Shipton, Philippa B. Mills, Joy W. Kiano, Norihiko Misawa, Rachel G. Drake, Wolfgang Schuch, and Peter M. Bramley
Commentaries
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