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Atomic structure of the Campylobacter jejuni flagellar filament reveals how ε Proteobacteria escaped Toll-like receptor 5 surveillance
Mark A. B. Kreutzberger, Cheryl Ewing, Frederic Poly, Fengbin Wang, and Edward H. Egelman

PNAS first published July 8, 2020. https://doi.org/10.1073/pnas.2010996117
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Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation
Wei Wang, Wanqiu Li, Xueliang Ge, Kaige Yan, Chandra Sekhar Mandava, Suparna Sanyal, and Ning Gao

PNAS July 7, 2020 117 (27) 15609-15619; first published June 22, 2020. https://doi.org/10.1073/pnas.1914323117
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Primordial emergence of a nucleic acid-binding protein via phase separation and statistical ornithine-to-arginine conversion
Liam M. Longo, Dragana Despotović, Orit Weil-Ktorza, Matthew J. Walker, Jagoda Jabłońska, Yael Fridmann-Sirkis, Gabriele Varani, Norman Metanis, and Dan S. Tawfik

PNAS July 7, 2020 117 (27) 15731-15739; first published June 19, 2020. https://doi.org/10.1073/pnas.2001989117
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Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex
Tomas Malinauskas, Tina V. Peer, Benjamin Bishop, Thomas D. Mueller, and Christian Siebold

PNAS July 7, 2020 117 (27) 15620-15631; first published June 23, 2020. https://doi.org/10.1073/pnas.2000561117
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Closing and opening of the RNA polymerase trigger loop
Abhishek Mazumder, Miaoxin Lin, Achillefs N. Kapanidis, and Richard H. Ebright

PNAS July 7, 2020 117 (27) 15642-15649; first published June 22, 2020. https://doi.org/10.1073/pnas.1920427117
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A combined activation mechanism for the glucagon receptor
Giulio Mattedi, Silvia Acosta-Gutiérrez, Timothy Clark, and Francesco Luigi Gervasio

PNAS July 7, 2020 117 (27) 15414-15422; first published June 22, 2020. https://doi.org/10.1073/pnas.1921851117
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Discontinuous fibrous Bouligand architecture enabling formidable fracture resistance with crack orientation insensitivity
Kaijin Wu, Zhaoqiang Song, Shuaishuai Zhang, Yong Ni, Shengqiang Cai, Xinglong Gong, Linghui He, and Shu-Hong Yu

PNAS July 7, 2020 117 (27) 15465-15472; first published June 22, 2020. https://doi.org/10.1073/pnas.2000639117
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The mechanochemistry of the kinesin-2 KIF3AC heterodimer is related to strain-dependent kinetic properties of KIF3A and KIF3C
Brandon M. Bensel, Michael S. Woody, Serapion Pyrpassopoulos, Yale E. Goldman, Susan P. Gilbert, and E. Michael Ostap

PNAS July 7, 2020 117 (27) 15632-15641; first published June 22, 2020. https://doi.org/10.1073/pnas.1916343117
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Phase transition of RNA−protein complexes into ordered hollow condensates
Ibraheem Alshareedah, Mahdi Muhammad Moosa, Muralikrishna Raju, Davit A. Potoyan, and Priya R. Banerjee

PNAS July 7, 2020 117 (27) 15650-15658; first published June 22, 2020. https://doi.org/10.1073/pnas.1922365117
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Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces
Sai Venkatesh Pingali, Micholas Dean Smith, Shih-Hsien Liu, Takat B. Rawal, Yunqiao Pu, Riddhi Shah, Barbara R. Evans, Volker S. Urban, Brian H. Davison, Charles M. Cai, Arthur J. Ragauskas, Hugh M. O’Neill, Jeremy C. Smith, and Loukas Petridis

PNAS first published July 7, 2020. https://doi.org/10.1073/pnas.1922883117

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Photos by E. Goetze, K. Peijnenburg, D. Perrine, Hawaii Seafood Council (B. Takenaka, J. Kaneko), S. Haddock, J. Drazen, B. Robison, DEEPEND (Danté Fenolio), and MBARI.

Opinion: Midwater ecosystems must be considered when evaluating environmental risks of deep-sea mining

We need more data on the risks mining poses to ocean life and ecosystems.

Photos by E. Goetze, K. Peijnenburg, D. Perrine, Hawaii Seafood Council (B. Takenaka, J. Kaneko), S. Haddock, J. Drazen, B. Robison, DEEPEND (Danté Fenolio), and MBARI.

Image credit: Under Earth Images/Dave Bunnell.

Core Concept: Lava tubes may be havens for ancient alien life and future human explorers

The formations offer both hospitable conditions and insights into geological history.

Image credit: Under Earth Images/Dave Bunnell.

Breaking the STEM ceiling

Fabiola Gianotti, Marcia McNutt, and Donna Shalala discuss the past, present, and future of women in STEM.

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Bioluminescent backlighting and signaling in squids

Complex visual signaling and semantics in deep-ocean-dwelling cephalopods.

Bilateral symmetry in the fossil record

The bilaterian Ikaria wariootia represents one of the oldest organisms with anterior and posterior differentiation.

Image credit: Sohail Wasif (University of California, Riverside, CA).

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