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Research Article

Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation

Xiang Li, Wei Wei, Qiong-Yi Zhao, Jocelyn Widagdo, Danay Baker-Andresen, Charlotte R. Flavell, Ana D’Alessio, Yi Zhang, and Timothy W. Bredy
PNAS first published April 22, 2014; https://doi.org/10.1073/pnas.1318906111
Xiang Li
aQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia;
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Wei Wei
aQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia;
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Qiong-Yi Zhao
aQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia;
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Jocelyn Widagdo
aQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia;
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Danay Baker-Andresen
aQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia;
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Charlotte R. Flavell
aQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia;
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Ana D’Alessio
bWhitehead Institute for Biomedical Research, Cambridge, MA, 02142;
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Yi Zhang
cHarvard Medical School, Boston, MA, 02115; and
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Timothy W. Bredy
aQueensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia;
dCenter for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, University of California, Irvine, CA, 92617
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  • For correspondence: t.bredy@uq.edu.au
  1. Edited* by James L. McGaugh, University of California, Irvine, CA, and approved March 27, 2014 (received for review October 7, 2013)

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5-hydroxymethylcytosine and adaptation
Xiang Li, Wei Wei, Qiong-Yi Zhao, Jocelyn Widagdo, Danay Baker-Andresen, Charlotte R. Flavell, Ana D’Alessio, Yi Zhang, Timothy W. Bredy
Proceedings of the National Academy of Sciences Apr 2014, 201318906; DOI: 10.1073/pnas.1318906111

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5-hydroxymethylcytosine and adaptation
Xiang Li, Wei Wei, Qiong-Yi Zhao, Jocelyn Widagdo, Danay Baker-Andresen, Charlotte R. Flavell, Ana D’Alessio, Yi Zhang, Timothy W. Bredy
Proceedings of the National Academy of Sciences Apr 2014, 201318906; DOI: 10.1073/pnas.1318906111
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Proceedings of the National Academy of Sciences: 118 (3)
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