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Research Article

ASBEL–TCF3 complex is required for the tumorigenicity of colorectal cancer cells

Kenzui Taniue, Akiko Kurimoto, Yasuko Takeda, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yuki Katou, Katsuhiko Shirahige, and Tetsu Akiyama
PNAS first published October 21, 2016; https://doi.org/10.1073/pnas.1605938113
Kenzui Taniue
aLaboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan;
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Akiko Kurimoto
aLaboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan;
bOncology Research Laboratories, Daiichi Sankyo Co., Ltd, Shinagawa-ku, Tokyo 140-8710, Japan;
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Yasuko Takeda
aLaboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan;
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Takeshi Nagashima
cLaboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan;
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Mariko Okada-Hatakeyama
cLaboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan;
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Yuki Katou
dLaboratory of Genome Structure and Function, Research Center for Epigenetic Disease, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan
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Katsuhiko Shirahige
dLaboratory of Genome Structure and Function, Research Center for Epigenetic Disease, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan
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Tetsu Akiyama
aLaboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan;
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  • For correspondence: akiyama@iam.u-tokyo.ac.jp
  1. Edited by Robert N. Eisenman, Fred Hutchinson Cancer Research Center, Seattle, WA, and approved September 20, 2016 (received for review April 14, 2016)

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Article Information

201605938
DOI: 
https://doi.org/10.1073/pnas.1605938113
PubMed: 
27791078

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published October 21, 2016.


Author Information

  1. Kenzui Taniuea,1,
  2. Akiko Kurimotoa,b,1,
  3. Yasuko Takedaa,
  4. Takeshi Nagashimac,
  5. Mariko Okada-Hatakeyamac,
  6. Yuki Katoud,
  7. Katsuhiko Shirahiged, and
  8. Tetsu Akiyamaa,2
  1. aLaboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan;
  2. bOncology Research Laboratories, Daiichi Sankyo Co., Ltd, Shinagawa-ku, Tokyo 140-8710, Japan;
  3. cLaboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan;
  4. dLaboratory of Genome Structure and Function, Research Center for Epigenetic Disease, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan
  1. Edited by Robert N. Eisenman, Fred Hutchinson Cancer Research Center, Seattle, WA, and approved September 20, 2016 (received for review April 14, 2016)

Footnotes

  • ↵1K.T. and A.K. contributed equally to this work.

  • ↵2To whom correspondence should be addressed. Email: akiyama{at}iam.u-tokyo.ac.jp.
  • Author contributions: K.T., A.K., and T.A. designed research; K.T., A.K., Y.T., Y.K., and K.S. performed research; K.T., T.N., and M.O.-H. analyzed data; Y.K. and K.S. performed sequence analysis; and K.T. and T.A. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

  • Data deposition: The data reported in this paper have been deposited in the DNA Data Bank of Japan Sequence Read Archive (DRA) database, trace.ddbj.nig.ac.jp/dra/index.html (accession no. DRA004515).

  • This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1605938113/-/DCSupplemental.

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Article usage

Article usage: October 2016 to January 2021

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Oct 201627344687
Nov 20164495112188
Dec 20163103841
Total 20167539196316
Jan 20171792934
Feb 20171194117
Mar 20171212623
Apr 2017771117
May 2017761917
Jun 2017582225
Jul 2017911030
Aug 2017693124
Sep 2017601717
Oct 2017431611
Nov 2017541616
Dec 2017222029
Total 2017969258260
Jan 2018371519
Feb 2018192511
Mar 2018304027
Apr 2018313511
May 2018303412
Jun 2018253526
Jul 2018293418
Aug 2018242323
Sep 201825328
Oct 201852720
Nov 201833422
Dec 201813014
Total 2018259364211
Jan 201932124
Feb 20191188
Mar 201903122
Apr 201924317
May 201902013
Jun 201922411
Jul 201903215
Aug 201912519
Sep 20192147
Oct 201922413
Nov 201902913
Dec 201953023
Total 201918311185
Jan 202023513
Feb 202042518
Mar 202024218
Apr 20204177
May 20202298
Jun 202014319
Jul 20204378
Aug 202002010
Sep 202072713
Oct 202032810
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Dec 202015279
Total 202054362152
Jan 202141810
Total 202141810
Total884315091134
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ASBEL–TCF3 complex and colorectal tumorigenesis
Kenzui Taniue, Akiko Kurimoto, Yasuko Takeda, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yuki Katou, Katsuhiko Shirahige, Tetsu Akiyama
Proceedings of the National Academy of Sciences Oct 2016, 201605938; DOI: 10.1073/pnas.1605938113

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ASBEL–TCF3 complex and colorectal tumorigenesis
Kenzui Taniue, Akiko Kurimoto, Yasuko Takeda, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yuki Katou, Katsuhiko Shirahige, Tetsu Akiyama
Proceedings of the National Academy of Sciences Oct 2016, 201605938; DOI: 10.1073/pnas.1605938113
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