Supporting information for Smoot et al. (March 26, 2002) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.062526099.

Supporting Figure 4A
Supporting Figure 4B

Fig. 4. Linear map of open reading frames in MGAS8232. ORFs are color coded by cluster of orthologous gene functional categories (violet, DNA replication, recombination, and repair; cyan, transcription; forest green, translation, ribosomal structure, and biosynthesis; green, cell division and partitioning; olive green, cell envelope biosynthesis; yellow, energy production and conversion; light purple, lipid metabolism; light blue, nucleotide transport and metabolism; light gray, carbohydrate transport and metabolism; dark gray, amino acid transport and metabolism; light brown, inorganic ion transport and metabolism; tan, coenzyme metabolism; green-blue, secondary metabolite biosynthesis, transport, and metabolism; salmon, cell motility and secretion; orange, posttranslational modification, protein turnover, and chaperones; red signal transduction mechanisms; rose, general function prediction only; light pink, function unknown). RNA operons (magenta), proven and putative virulence factors (purple), and transposases (blue) are also identified. ORFs are identified either with gene names or spyM18 numbers. ORF orientation is indicated by box position on the centerline (boxes above the line are encoded in the positive strand whereas boxes below the line are encoded in the negative strand). Phage regions are identified with black bars on the centerline. [Recommendation: View figures at increased magnification.]