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Research Article

Persistent cannabis users show neuropsychological decline from childhood to midlife

Madeline H. Meier, Avshalom Caspi, Antony Ambler, HonaLee Harrington, Renate Houts, Richard S. E. Keefe, Kay McDonald, Aimee Ward, Richie Poulton, and Terrie E. Moffitt
  1. aDuke Transdisciplinary Prevention Research Center, Center for Child and Family Policy,
  2. bDepartment of Psychology and Neuroscience, and
  3. cInstitute for Genome Sciences and Policy, Duke University, Durham, NC 27708;
  4. dDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710;
  5. eSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London SE5 8AF, United Kingdom; and
  6. fDunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, School of Medicine, University of Otago, Dunedin 9054, New Zealand

See allHide authors and affiliations

PNAS first published August 27, 2012; https://doi.org/10.1073/pnas.1206820109
Madeline H. Meier
aDuke Transdisciplinary Prevention Research Center, Center for Child and Family Policy,
bDepartment of Psychology and Neuroscience, and
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  • For correspondence: madeline.meier@duke.edu
Avshalom Caspi
aDuke Transdisciplinary Prevention Research Center, Center for Child and Family Policy,
bDepartment of Psychology and Neuroscience, and
cInstitute for Genome Sciences and Policy, Duke University, Durham, NC 27708;
dDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710;
eSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London SE5 8AF, United Kingdom; and
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Antony Ambler
eSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London SE5 8AF, United Kingdom; and
fDunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, School of Medicine, University of Otago, Dunedin 9054, New Zealand
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HonaLee Harrington
bDepartment of Psychology and Neuroscience, and
cInstitute for Genome Sciences and Policy, Duke University, Durham, NC 27708;
dDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710;
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Renate Houts
bDepartment of Psychology and Neuroscience, and
cInstitute for Genome Sciences and Policy, Duke University, Durham, NC 27708;
dDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710;
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Richard S. E. Keefe
dDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710;
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Kay McDonald
fDunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, School of Medicine, University of Otago, Dunedin 9054, New Zealand
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Aimee Ward
fDunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, School of Medicine, University of Otago, Dunedin 9054, New Zealand
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Richie Poulton
fDunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, School of Medicine, University of Otago, Dunedin 9054, New Zealand
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Terrie E. Moffitt
aDuke Transdisciplinary Prevention Research Center, Center for Child and Family Policy,
bDepartment of Psychology and Neuroscience, and
cInstitute for Genome Sciences and Policy, Duke University, Durham, NC 27708;
dDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710;
eSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London SE5 8AF, United Kingdom; and
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Supporting Information

Files in this Data Supplement:

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  • Download Table_S02 (DOCX)
  • Download Table_S03 (DOCX)

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