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Research Article
Mechanism of β-arrestin recruitment by the μ-opioid G protein-coupled receptor
View ORCID ProfileAmirhossein Mafi, View ORCID ProfileSoo-Kyung Kim, and View ORCID ProfileWilliam A. Goddard III
Amirhossein Mafi
aMaterials and Process Simulation Center (139-74), California Institute of Technology, Pasadena, CA 91125
Soo-Kyung Kim
aMaterials and Process Simulation Center (139-74), California Institute of Technology, Pasadena, CA 91125
William A. Goddard III
aMaterials and Process Simulation Center (139-74), California Institute of Technology, Pasadena, CA 91125
Supporting Information
- Download Appendix (PDF)
- Download Movie_S01 (MP4) - βarr2 recruitment by pp-μOR and morphine.
- Download Movie_S02 (MP4) - Finger loop as a major driver of βarr2 coupling to the core pp-μOR.
- Download Movie_S03 (MP4) - Emergence of polar anchor between βarr2 and ICL3 of pp-μOR.
- Download Movie_S04 (MP4) - Emergence of polar anchor between βarr2 and ICL2 of pp-μOR.