Table S1.

Time course of oxidative modifications of D1 and D2 proteins

Protein0 min15 min30 min
D1316T +go*316T+go1M+to
317W+do,go317W+do, go, kyn7R+ca
319D+go328M+go130E+go
328M+go331M+go131W+go
331M+go332H+go315N+go
333E+go316T+go
317W+do, go, kyn
319D+go
329E+go
331M+go
332H+go
333E+go
D218M+go18M+go18M+go
246M+go246M,+go242E+de
247V+go247V+go244Y+go
329M+go328W+go,245S+go
329M+go, do 333D+go246M+go
334Q+go247V+go
336H+hro328W+do, kyn 329M+do, go, to
333D+gam
341F+go
342P+go
343E+ca, de
344E+de, go
345V+go
  • * Oxidative modifications key: do, double oxidation, +31.99 Da; gam, Glu/Asp decarboxylation, −30.01 Da; go, general oxidation, +15.99 Da; hro, histidine ring opening, −10.03 Da; kyn, kynurenine formation, +3.99 Da; to, triple oxidation, +47.98 Da. In some instances, more than one type of modification was observed for a particular amino acid residue on different identified peptides, these are separated by commas. It should be noted that whereas a total of 12 different types of oxidative modifications were incorporated into the MassMatrix searches, only these 6 types were actually observed in this study.