Table 2. Characteristics of 30 known genes
Divergence at part of genes
Gene name GenBank accession no. Length sequenced in human, bp Percentage sequenced in chimpanzee Overall divergence between human and chimp, % Promoter, % Coding, % Exon-intron junction, % Nonsynonymous change, no. Synonymous change, no. Ka Ks Ka/Ks P* Divergence at amino acid level, %
ADARB1 AL163301 4,826 59.10 0.60 1.07 0.08 1.11 1 0 0.0006 0.0000 NA 1.0000 0.23
AIRE AP001754 6,393 68.37 1.17 1.72 1.01 0.63 5 4 0.0047 0.0084 0.5601 0.7078 1.68
ATP5A AP001694 2,079 100.00 1.06 0.42 1.53 1.69 0 0 0.0000 0.0000 NA 1.0000 0.00
B3GALT5 AL163280 3,886 63.29 1.63 1.96 1.41 2.78 6 7 0.0092 0.0225 0.4085 0.9110 1.95
C210RF258 AP001745-C 5,402 49.44 0.82 NS 1.22 0.59 3 0 0.0036 0.0000 NA 1.0000 0.91
CBR1 AP001724 2,822 50.30 2.05 2.06 1.26 2.22 0 5 0.0000 0.0207 0.0000 0.9979 0.00
CCT8 AL163249 6,213 47.48 0.64 0.16 0.42 1.43 3 0 0.0062 0.0000 NA 1.0000 1.27
COL6A2 AP001759 2,628 73.48 0.21 0.00 0.35 0.00 4 0 0.0049 0.0000 NA 1.0000 1.06
CRYAA AP001748 3,235 36.75 1.43 1.75 0.48 0.83 1 0 0.0066 0.0000 NA 1.0000 1.43
DSCR2 AL163279-C 2,886 42.69 0.89 0.63 1.32 3.36 2 0 0.0014 0.0000 NA 1.0000 0.96
HSF2BP AP001752-C 4,793 37.03 0.73 0.78 0.96 0.51 1 0 0.0015 0.0000 NA 1.0000 2.88
IFNAR1 AP001716 5,421 37.63 0.88 1.24 0.69 0.41 3 1 0.0024 0.0019 1.2602 0.2459 1.54
IFNGR2 AP001717 3,856 41.57 0.69 NS 0.87 0.33 2 2 0.0062 0.0144 0.4322 0.6486 1.30
KCNE1 AP001720-C 2,506 67.32 1.36 1.03 2.51 NS 6 4 0.0221 0.0303 0.7278 0.5774 4.51
KIAA0539 AP001713-C 7,481 63.20 1.08 0.38 1.20 1.40 4 12 0.0033 0.0323 0.1031 0.3164 0.90
MX1 AL163285 8,143 66.66 0.94 0.84 0.93 1.05 6 7 0.0065 0.0146 0.4443 0.8844 1.28
MX2 AL163285 5,949 81.74 1.32 1.76 0.74 1.43 8 5 0.0071 0.0080 0.8797 0.4859 1.37
PCNT AP001760 22,136 76.29 0.73 0.00 0.92 0.62 35 37 0.0073 0.0137 0.5280 0.9953 1.33
PDXK AP001752 5,302 47.98 1.26 1.83 0.30 0.64 1 0 0.0036 0.0000 NA 1.0000 0.89
PRED14 AP001679 1,456 56.80 1.45 0.24 2.52 NS 4 0 0.0343 0.0000 NA 1.0000 7.55
PRED22 AP001693-C 5,031 74.18 0.75 0.37 0.39 1.05 2 0 0.0050 0.0000 NA 1.0000 1.18
PRSS7 AL163218-C 2,414 74.23 0.73 0.56 0.58 1.47 2 0 0.0009 0.0000 NA 1.0000 1.74
SAMSN-1 AL163206-C 4,916 67.05 1.06 2.38 0.47 0.51 3 1 0.0050 0.0065 0.7732 0.0625 1.05
SH3BGR AL163280 3,339 63.10 0.76 1.07 0.38 0.69 2 0 0.0029 0.0000 NA 1.0000 1.13
TFF3 AP001746-C 2,946 22.57 1.50 NS 0.60 0.98 1 0 0.0056 0.0000 NA 1.0000 1.80
TMPRSS2 AL163286-C 6,879 59.25 0.91 0.71 0.24 1.44 2 0 0.0036 0.0000 NA 1.0000 0.73
TRPC7 APP001754 15,120 74.79 1.03 0.83 1.10 0.96 17 19 0.0054 0.0139 0.3912 0.9958 1.56
TTC3 AP001728 18,213 84.85 0.67 0.70 0.36 0.88 14 6 0.0040 0.0029 1.3919 0.1820 0.76
USP16 AL163249 7,752 77.52 0.53 0.22 0.89 0.49 8 6 0.0046 0.0073 0.6245 0.7304 1.52
WDR4 AB039887 6,097 57.68 1.02 1.07 0.36 0.73 2 0 0.0039 0.0000 NA 1.0000 1.07
  • NS, no data available because the region was not sequenced; NA, not applicable for calculation

  • * P for Ka/Ks = 1 when Ka/Ks ≥ 1