Table 1. Biodistribution of i.v. injected 99mTc-18B7 and 99mTc-MOPC21 antibodies at 24 h postinjection in mice intratracheally infected with CN and healthy BALB/c mice
Mice
Organ Infected with CN, 99mTc-18B7 injection Infected with CN, 99mTc-MOPC21 injection Infected with CN and pretreated with 1 mg of nonradioactive 18B7 before 99mTc-18B7 injection Healthy controls, 99mTc-18B7 injection
Blood 12.77 (1.22) 9.02 (2.13) 8.25 (0.22) 8.0 (0.70)
Liver 8.71 (1.22) 1.27 (0.34) 6.71 (0.52) 4.77 (0.32)
Kidney 9.88 (0.21) 3.07 (1.00) 7.26 (0.28) 4.47 (1.31)
Spleen 4.86 (0.14) 1.50 (0.09) 2.53 (0.54) 2.56 (0.62)
Stomach 2.43 (0.08) 1.04 (0.33) 5.39 (1.32) 1.57 (0.35)
Lungs 10.27 (1.02) 2.66 (0.50) 4.57 (0.33) 4.57 (0.59)
  • Results were obtained from n = 3 mice per time point and were tabulated as percent initial dose per g. Numbers in parentheses are SD.