Table 1. Vaccination with M. tuberculosis H37Rv ΔRD1 protects as well as M. bovis BCG (day 28 postvaccination)
3-month challenge (log10 cfu) 8-month challenge (log10 cfu)
Vaccination strain Lung Spleen Lung Spleen
4.77 ± 0.06 3.57 ± 0.21 6.61 ± 0.13 5.26 ± 0.11
BCG 3.96 ± 0.20** 2.18 ± 0.18*** 5.07 ± 0.10*** 3.85 ± 0.17**
H37RvΔRD1 3.97 ± 0.39** 2.12 ± 0.12*** 5.11 ± 0.14*** 4.00 ± 0.33**
  • ** , P < 0.01

  • *** , P < 0.001