Table 1. Mode of death and production of hyphae in morphological mutants of C. albicans after treatment with 40 mM acetic acid
Strain
Character Value efg1cph1rim101tec1 CaF-2
Necrotic Cells, % 22 28 10 28 20
t value 0.104 0.397 0.600 0.397 0.253
P 0.918 0.692 0.550 0.692 0.800
Significance NSD NSD NSD NSD NSD
Apoptotic Cells, % 35 13 32 24 36
t value 0.021 1.096 0.151 0.514 0.064
P 0.983 0.276 0.881 0.609 0.949
Significance NSD NSD NSD NSD NSD
Hyphae Hyphae, % 31 6 16 9 5
t value 3.841 0.789 2.248 1.298 0.521
P 0.0002 0.432 0.027 0.197 0.603
Significance *** NSD * NSD NSD
  • Data were compared against the population mean ± 1 SEM for the pooled control data collected for CaF-2 treated with 40 mM acetic acid (quadruplicate measures, each with n = 100). *, P<0.05; ***, P<0.001; NSD, not significantly different.

  • Critical tα(2),99 = 1.984 for P < 0.05; n = 100 for each mutant