Moran | Linear, independent of N | |||
---|---|---|---|---|
τ = 1 | ||||
r | N = 10 | N = 20 | τ_{0} = 1 | τ_{0} = 10 |
2 | 5.0 | 10.0 | 0.5 | 0.05 |
1.2 | 1.99 | 3.42 | 0.5 | 0.05 |
1 | 1 | 1 | 0.5 | 0.05 |
0.8 | 0.30 | 0.06 | 0.5 | 0.05 |
0.5 | 0.01 | 10 | 0.5 | 0.05 |
In the Moran process with random cell death, the probability that mutant cells have become fixed is P(t) = N ρut/τ. In the linear process, we have P(t) = ut/(2τ_{0}). We list the factor that multiplies ut. In the Moran process, advantageous mutants, r > 1, accumulate faster than neutral mutants, r = 1, which accumulate faster than deleterious mutants, r < 1. In the linear process, mutants accumulate independent of their selective value at a rate that is τ/(2τ_{0}) times the rate of neutral evolution in the Moran process.