Table 1. Metabolic parameters of 14-month-old FKOγ mice
Genotype Con FKOγ
Blood glucose, mg/dl
    Basal 137 ± 5.6 125 ± 5.4
    Clamp 148 ± 1.9 148 ± 0.96
Blood insulin, ng/ml
    Basal 0.87 ± 0.02 0.82 ± 0.25
    Clamp 9.4 ± 0.6 10.3 ± 0.6
FFA (mmol/l)
    Basal 0.82 ± 0.09 0.99 ± 0.05
    Clamp 0.43 ± 0.02* 0.58 ± 0.06*#
Blood triglyceride, mg/dl 122.8 ± 15 151 ± 19
Leptin, ng/ml 3.76 ± 1.0 1.5 ± 0.33#
Acrp30, mg/ml 20.9 ± 2.2 3.9 ± 0.72#
Muscular TG, μmol/g of tissue 5.7 ± 2.0 7.6 ± 3.1
Liver TG, μmol/g of tissue 6.3 ± 2.0 11.7 ± 4.2#
  • Data represent the mean ± SEM (n = 8). Blood was obtained from the Con and FKOγ mice before and during clamping study. *, P < 0.05, basal vs. clamping; #, P < 0.05, Con vs. FKOγ.