Table 2

Pancreatic tissue concentration of islet hormones in male mice, 14–22 wk

HormoneGcgr+/+Gcgr−/−
Insulin8,387  ± 8146,391  ± 961
Somatostatin1,452  ± 4514,270  ± 1,021*
Glucagon + ProGlu542  ± 1254,933  ± 1,450**
GLP-l amide25  ± 2233  ± 35**
Total GLP-163  ± 81,633  ± 427**
  • Concentrations are in fmol/mg. Data are the mean ± SEM, n = 11–12. 

  • * , P < 0.05; 

  • ** , P < 0.01; 

  • ** , P < 0.001.