Table S1.

Clinical diagnostic characteristics of patient samples

Identifier codeDiagnosisAge, y (sex)Hb, g/dLPCV, %Fe, mg/dLLDH, U/lIg gene rearrangementCytogenetics (classical karyotype or FISH)Immunophenotype (immunohistochemistry and/or flow cytometry)Sites of involvementStage at diagnosis
P1MCL67 (M)13.939.5NDNDMonoclonal IgHCCND1-IgH+ (dual-fusion FISH)CD20+, CD79a+, CD3, CD5+, CD23, Cyclin D1+, BCL2+Peripheral bloodIV
Bone marrow
Left cervical lymph node
P2MCL68 (M)1237ND198Monoclonal IgHComplex translocation involving chr. 11 and chr. 14 CCND1-IgH+ (dual-fusion FISH)CD20+, CD79a+, CD3, CD5+, CD23, Cyclin D1+, CD43+, CD10Peripheral bloodIV
Bone marrow
Right supraclavicular lymph node
P3MCL75 (F)11.937ND301Monoclonal IgHNDCD20+, CD19+, CD3, CD5+, CD23, Cyclin D1+, CD10, FMC7+, Igκ-restrictedPeripheral bloodIV
Bone marrow
Right cervical lymph node
P4MCL55 (F)15.846.9ND301Monoclonal IgHCCND1-IgH+ (dual-fusion FISH)CD20+, CD3, CD2, CD5+, CD23, Cyclin D1+, CD10, CD43+, CD45ROPeripheral bloodIV
Bone marrow
Left axillary lymph node
Abdomen
P5FL62 (F)14.944.5NANAMonoclonal IgHBCL2-IgH+ (dual-fusion FISH)CD20+, CD3, CD10+, BCL2+Peripheral bloodIII
Left cervical lymph node
Abdomen
P6FL79 (M)10.330.730186Monoclonal IgHNDCD20+, CD19+, CD3−, CD4, CD5, CD7, CD10+, BCL2++, Igκ-restrictedPeripheral bloodIV
Bone marrow
Cervical lymph node
Axillary lymph node
P7FL63 (F)13.140.383NDNDBCL2-IgH+ (dual-fusion FISH)CD20+, CD79a+, CD3, CD5, CD45+, CD10+, BCL2+, BCL6+Right cervical lymph nodeIV
P8FL51 (M)NANANANANANACD20+, CD3, CD5, CD10+, BCL2+Left cervical lymph nodeNA
  • chr., chromosome; F, female; Hb, hemoglobin; LDH, lactate dehydrogenase; M, male; NA, not available; ND, not determined; PCV, packed cell volume.