Table 1. Surface reactivity of the 5B14 mAb on different cell types
Cells Histotype 5B14 mAb GD2 mAb
Resting NK cells - -
Activated NK cells - -
Resting T cells - -
PHA blasts - -
Resting B cells - -
Granulocytes - -
Monocytes +/- -
IDC ++ -
mDC ++ -
YT NK cell line - ++
NK92 NK cell line - -
CEMB T leukemia - -
Jurkat T leukemia - +/-
H9 T leukemia - +/-
HSB2 T leukemia
Raji Burkitt lymphoma - -
LCL 721.221 EBV cell line - -
EA Endothelial cells ++ -
K562 Erythroleukemia + -
MM6 Promyelocytic leukemia + -
U937 Myeloid leukemia + -
293T Embryonic fibroblasts ++ -
M14 Melanoma ++ -
FO-1 Melanoma ++ ++
Me 1074 Melanoma ++ ++
H460 Lung carcinoma ++ -
SMMC Hepatoma ++ -
HELA Cervical carcinoma ++ -
IGROV-1 Ovarian carcinoma ++ -
SKNEP Kidney carcinoma + -
A172 Glioblastoma ++ -
HT29 Colon carcinoma ++ -
CX2 Colon carcinoma ++ -
SKBr3 Breast carcinoma + -
MDAM B453 Breast carcinoma +/- -