Table 2. A selection of paralogous families in related genomes
Family no.
Occurrence, %
Function N. farcinicaM. tuberculosisS. avermitilis
1 ABC transporter ATP-binding protein 57 (1.00) 21 (0.53) 100 (1.32)
2 Short-chain dehydrogenase 87 (1.53) 44 (1.12) 68 (0.90)
3 TetR transcriptional regulator 75 (1.32) 25 (0.64) 51 (0.67)
4 Two-component response regulator 29 (0.51) 15 (0.38) 64 (0.84)
5 PE_PGRS/PPE 1 (0.02) 115 (2.93) 4 (0.05)
6 Acyl-CoA synthetase 37 (0.65) 21 (0.53) 34 (0.45)
7 Dehydrogenase 30 (0.53) 13 (0.33) 40 (0.53)
8 Acyl-CoA dehydrogenase 40 (0.70) 24 (0.61) 25 (0.33)
9 Transporter 26 (0.46) 7 (0.18) 44 (0.58)
10 ECF σ factor 17 (0.30) 9 (0.23) 38 (0.50)
11 Enoyl-CoA hydratase/isomerase 26 (0.46) 22 (0.56) 16 (0.21)
12 Aldehyde dehydrogenase 23 (0.41) 10 (0.25) 21 (0.28)
13 Cytochrome P450 21 (0.37) 12 (0.31) 27 (0.36)
14 LysR transcriptional regulator 20 (0.35) 3 (0.08) 27 (0.36)
15 Transporter 4 (0.07) 7 (0.18) 33 (0.44)
16 ABC transporter ATP-binding protein 15 (0.26) 5 (0.13) 19 (0.25)
17 Aminotransferase 14 (0.25) 7 (0.18) 19 (0.25)
18 Serine/threonine protein kinase 14 (0.25) 8 (0.20) 19 (0.25)
19 Oxidoreductase 19 (0.33) 12 (0.31) 11 (0.15)
20 Two-component sensor kinase 7 (0.12) 7 (0.18) 21 (0.28)
23 GntR transcriptional regulator 11 (0.19) 2 (0.05) 23 (0.30)
25 Glycosyltransferase 13 (0.23) 7 (0.18) 11 (0.15)
46 YrbE protein 12 (0.21) 8 (0.20) 2 (0.03)
53 Fibronectin-binding protein 12 (0.21) 4 (0.10) 0 (0.00)
58 MceB/C protein 10 (0.18) 8 (0.20) 2 (0.03)
62 Lipase/esterase 9 (0.16) 8 (0.20) 1 (0.01)
  • Numbers in parentheses indicate the percentage of the total population in that genome.