Table 1. Trp/Y(NO2) sites and extracted mean DA distances for α-syn
Solution rLLS,* Å χr2rgc, Å I′,§ Å χr2
W4-Y(NO2)19 (n = 15) pH 7.4 25 1.2 23 13 43
SDS 26 1.2 26 14 48
pH 4.4** 1.3 26 14 32
Y(NO2)19-W39 (n = 20) pH 7.4 30 1.1 29 13 7.6
SDS 1.4 26 10 12
pH 4.4 1.1 31 15 9.7
W4-Y(NO2)39 (n = 35) pH 7.4 34 1.4 43 16 1.4
SDS 34 1.2 43 17 2.9
pH 4.4 1.3 45 18 1.4
Y(NO2)74-W94 (n = 20) pH 7.4 1.2 31 15 28
SDS 1.4 26 11 39
pH 4.4 1.3 31 15 40
W94-Y(NO2)136 (n = 42) pH 7.4 33 1.2 43 14 1.7
SDS 1.1 52 20 5.4
pH 4.4 28 1.1 34 8.5 1.3
W4-Y(NO2)136 (n = 132) pH 7.4 1.6 62 8.9 3.8
SDS 2.1 72 12 4.5
pH 4.4 1.5 47 5.2 1.3
  • n, number of chain elements (residues); —, no entry.

  • * Mean DA distance obtained from LLS fits.

  • Reduced χ2.

  • Mean DA distance obtained from fits to a Gaussian chain model.

  • § Effective length for a chain element.

  • 20mM NaPi buffer.

  • 40 mM SDS in 20 mM NaPi buffer, pH 7.4.

  • ** 20 mM NaOAc buffer, pH 4.4.