Table 1. Summary of modifications detected in this study
Residue Modification H3 H3.3
K4 Monomethyl + +
Dimethyl + ++*
Trimethyl + ++*
K9 Monomethyl + +
Dimethyl ++* +
Trimethyl
Acetyl + ++*
K14 Monomethyl + +
Dimethyl + +
Trimethyl
Acetyl + ++*
K18 + K23 Acetyl + ++
K27 Monomethyl + +
Dimethyl + +
Trimethyl + +
K36 Monomethyl + +
Dimethyl + +
Trimethyl
K37 Monomethyl + +
Dimethyl + +
Trimethyl
K79 Monomethyl + ++* ,
Dimethyl + ++* ,
Trimethyl
  • +, observed; ++, relatively enriched.

  • * Quantified by ELISA

  • Quantified by MS

  • Axel Imhof, personal communication