Table 2. Kinetic rates and binding affinity of 80R antibody and ACE2 to S1-lg
Kon, M-1·s-1Koff, s-1Ka, M-1Kd, M
80R scFv 2.29 × 105 8.36 × 10-3 3.10 × 107 3.23 × 10-8
80R IgG1 3.88 × 105 6.18 × 10-4 6.28 × 108 1.59 × 10-9
ACE2 2.47 × 105 4.20 × 10-4 5.88 × 108 1.70 × 10-9
  • Kinetic rates and K a and K d were calculated using bia-evaluation software.