Table 1. Regional differences in cortical recruitment as a function of fitness
Study no./type Region Cluster size Max ZXYZ
Study 1, cross-sectional Right MFG1 2,045 3.75 32 52 27
SPL1 3,003 4.49 7.3 −70 56.7
VC1 247 2.55 −28 −92 8
ACC2 163 3.41 3.4 25.5 23.7
Study 2, randomized trial Right MFG1 368 3.28 27 63 19
SPL1 381 3.07 −8 −71 65.8
ACC1 60 2.87 2.3 30.1 18.8
  • This table describes the regions that differed in task-related activity as a function of fitness, including the size of the cluster, the maximum Z statistic for the cluster, and the location of the maximal Z statistic in Taliarach coordinates. In Study 1, (i) the large right MFG cluster had its peak in the right MFG and extended through the SFG, and (ii) the SPL cluster had its peak in the right SPL, and spread bilaterally to the left SPL. In Study 2, (i) the right MFG cluster showed peak activation close to the right MFG cluster in Study 1, but did not subsume the SFG, (ii) the SPL cluster peaked in the left SPL, and extended bilaterally into the right SPL. VC, visual cortex. Study 1: 1 = high fit > low fit; 2 = high fit < low fit. Study 2: 1 = exercise > control; 2 = exercise < control.