Table 1. Alleles of previously characterized genes
Mutant Phenotype Gene Mutation Nature of allele
bent body (bnb) Dorsalized spinal cord, left-right randomization, die at e9.0 Smo (19) Splice site Null
2A Dorsalized spinal cord, left-right randomization, die at e9.0 Kif3a Not determined Null
flexo (fxo) Abnormal diencephalon, no floor plate in caudal spinal cord, left-right randomization, polydactyly, die at e13-14 Polaris (13) Splice site Hypomorph
M1un Arrested unturned, variable cardia bifida; arrest at e9.0 Pten Missense (M134K) Hypomorph
DD1 Caudal paraxial mesoderm replaced by neural tubes Tbx6 Splice site Null