Table 1. MLEs of demographic and selective parameters in the two-epoch population growth model, obtained by using different functional classes of human SNPs
Functional class No. of SNPs MLEs LRT statistic (df) P value
Demography
    Noncoding 36,337 Embedded Image 9512.2 (2) «10-10
Selection
    Nonsynonymous 880 Embedded Image 66.14 (1) «10-10
    Synonymous 892 Embedded Image 0.238 (1) 0.890
    Noncoding indel 2,710 Embedded Image 5.128 (1) 0.024
  • τ ≡ time back to population size change; ν ≡ ratio of ancestral to current population size (NA/Nc); γ ≡ selection size parameter (2Ncs).