Table S2.

List of residues with net contact frequency (|Cij|0.5), positive value would indicate a contact between residue pairs i and j to be present exclusively in bound state and negative value states contact is predominantly formed in unbound state

ResIDResidues list with net contact frequency |Cij|0.5
G303S409 (−0.6)
E304S408 (−0.5)
E305R354 (−0.8), Y392 (−0.8), G410 (−0.7)
D306S409 (0.7), R411 (0.6)
I307P394 (−0.9), K393 (−0.9), V406 (−0.8), S409 (0.7), E395 (−0.6), R411 (0.9), R354 (0.9)
P308R354 (0.6), Q391 (−0.9)
R309Y392 (0.9), K393 (0.8), P394 (0.9), E395 (0.7), V406 (0.8), G410 (0.8)
E310Y392 (0.9)
E331G335 (0.7), A370 (−0.5)
D332N369 (−0.6)
G335E331 (0.7)
R354E305 (−0.8), I307 (0.9), P308 (0.6)
N369D332 (−0.6)
A370E331 (−0.5)
Q391P308 (−0.9)
Y392E305 (−0.8), R309 (0.9), E310 (0.9)
K393I307 (−0.9), R309 (0.8)
P394I307 (−0.9), R309 (0.9)
E395I307 (−0.6), R309 (0.7)
V406I307 (−0.8), R309 (0.8)
S408E304 (−0.5)
S409G303 (−0.6), D306 (0.7) I307 (0.7)
G410E305 (−0.7), R309 (0.8)
R411D306 (0.6), I307 (0.9)
K5I328 (0.8), G329 (0.7), H372 (0.8)
Q6N326 (1.0), I327 (0.9), I328 (0.9), S339 (0.8), F340 (0.7), H372 (0.7)
T7F325 (0.7), N326 (1.0), I327 (1.0), I328 (0.9), H372 (1.0), A376 (1.0)
S8F325 (1.0), N326 (1.0), I327 (1.0), L342 (0.7), K380 (0.6)
V9R318 (0.8), T321 (0.7), G322 (1.0), L323 (1.0), G324 (1.0), F325 (1.0), N326 (1.0), I327 (1.0), A376 (0.9), L379 (1.0), K380 (0.7)