Table 1.

Effect of transmission route on virulence of Pla Y. pestis

Y. pestis strainTransmission route
i.v.IDFleabite
Wild type<10468/10
Δpla <101.7 × 106 3/10
Δpla (complemented)<10178/10
  • LD50 values are given for i.v. and ID injection and disease incidence for fleabite transmission (no. of mice that developed terminal disease/no. of mice challenged).