Table 1.

Spontaneous chromosomal aberrations are reduced in Brca2 mutant cells stably expressing BRC-RPA fusion proteins

Cell lineNo. of cellsAbnormal cells, %Breaks, %Chromatid exchanges, %Total breaks ± SEM, %
V791506707 ± 0.7
V-C8150731372141 ± 17
    +BRC3RPA1501723023 ± 5
    +BRC3ΔRPA150651282132 ± 21
    +BRC1-4RPA1502733033 ± 5