Table 1.

Bactericidal activity of mice polyclonal antibodies

ImmunogensStrains
MC582996NZ98/254
FCAAl(OH)3FCAAl(OH)3FCAAl(OH)3
Antigens
    GNA213216,384* 51216,3841,02416,384512
    GNA1030<4<42,048<4<48
    GNA2091<4<4<4<4<4<4
    GNA187065,53616,38464<416,38464
    NadA5121,0244,0964,096<4<4
Fusions
    GNA2132–1030n.d.2,048n.d.2,048n.d.4,096
    GNA2091–1870n.d.32,768n.d.<4n.d.1,024
Vaccine
    5CVMB65,53632,7688,1924,09616,3844,096
  • *Bactericidal titers were expressed as the reciprocal of the serum dilution yelding ≥50% bactericidal killing. n.d., not determined.