Table 1.

Cadherin-binding parameters

Cadherin pairDensity, cadherins per μm2 (×103)Distance, Å; F/R, mN/m; and bond energy, kBT
Inner bondMiddle bondOuter bond
C-CAD/C-CAD9.5 ± 1383 ± 6; 1.9 ± 0.4; 7.8455 ± 6; 1.7 ± 0.4; 6.9536 ± 3; 1.0 ± 0.3; 4.1
E-CAD/E-CAD10 ± 1388 ± 5; 1.6 ± 0.3; 6.2525 ± 5; 0.6 ± 0.1; 2.5
N-CAD/N-CAD7 ± 0.7391 ± 10; 0.35 ± 0.04; 2.1468 ± 12; 0.23 ± 0.03; 1.5543 ± 9; 0.14 ± 0.03; 1.0
E-CAD/C-CAD9/9384 ± 8; 1.34 ± 0.4; 5.8471 ± 5; 0.8 ± 0.2; 3.5541 ± 10; 0.45 ± 0.1; 2.2
N-CAD/E-CAD7/7386 ± 8; 1.2 ± 0.2; 6.6474 ± 8; 0.7 ± 0.1; 4.0535 ± 4; 0.34 ± 0.04; 2.1
N-CAD/C-CAD7/11389 ± 5; 1.43 ± 0.18; 7.8471 ± 6; 1.19 ± 0.07; 6.6536 ± 3; 0.69 ± 0.08; 3.9
  • —, not detected.