Table 1.

Incidences of lung cancer, dysplasia, and multiple lung cancers in nontransgenic control and transgenic mice

LineNCancers
Dysplasia
Multiple cancers
N (%)PN (%)PN (%)P
Tg 484 (8.3)2 (4.2)0 (0)
Line 1409 (22.5)0.0676 (15)0.0821 (2.5)0.37
Line 2169 (56.3)0.00021 (6.3)0.760 (0)1.0
Line 3427 (16.7)0.1984 (9.5)0.271 (2.4)0.35
Line 43417 (50)<0.000111 (32.3)0.0017 (20.6)0.0026
  • Summary of incidences (number, N, and percentage) of lung cancer, dysplasia, and multiple lung cancers in nontransgenic (Tg) control mice, WT cyclin E transgenic lines 1 and 2, and degradation-resistant cyclin E transgenic lines 3 and 4.