Table 2.

Supporting capacity of Sertoli cells

Total GC/SCSpg/SCSpc/SCRspd/SCEspd/SC
WT (n = 4)15.5 ± 1.10.7 ± 0.16.2 ± 0.45.2 ± 0.63.3 ± 0.3
SPARKI (n = 5)12.6 ± 0.80.6 ± 0.16.1 ± 0.33.7 ± 0.42.1 ± 0.3
SP/WT (%)81%* 89%98%71%* 63%*
  • Values are the averages ± SEM of the nuclear volumes of each cell type per testis (in mm3 per testis) of n samples. SC, sertoli cell; GC, germ cell; Spg, spermatogonia; Spc, spermatocytes; Rspd, round spermatids; Espd, elongate spermatids.

  • *Ratios are significantly different (P < 0.07; Student's t test) between SPARKI and wild-type controls.