Table 1.

Characteristics of type 1 diabetic patients studied

Patient no.Age, yrSexTime from diagnosisβ cell functionEnteroviral infection of β cellsβ cell destructionInsulitis
126F* ImpairedYesNoMinor; dominated by NK cells; no evidence for autoreactive T cells
219M9 monthsPartially lostYesNoMinor; dominated by NK cells; no evidence for autoreactive T cells
315F1 weekLostYesLimitedMinor; dominated by NK cells; no evidence for autoreactive T cells
414F8 monthsLostNoYesModerate T cell infiltrate; no NK cells
55M1 weekLostNoYesModerate T cell infiltrate; no NK cells
64F1 weekLostNoYesModerate T cell infiltrate; no NK cells
  • M, male; F, female.

  • *Patient 1 was a recipient of a whole pancreas graft, which was removed after 38 months because of recurrent urinary tract infections.