Table 1.

Ninety-seven percent OTUs enriched or depleted in IBD subset

Top Blast hit*Phylum ΔPrevalence, %
Depleted in IBD subset
    Bacterium mpn-isolate group 5 Bacteroidetes; Bacteroidales −42.3
    Bacterium mpn-isolate group 18 Firmicutes; Lachnospiraceae −37.7
    Butyrate-producing bacterium A2–A165 Firmicutes; Lachnospiraceae −34.0
    Butyrate-producing bacterium SR1/1 Firmicutes; Lachnospiraceae −32.5
     Bacteroides thetaiotaomicron Bacteroidetes; Bacteroidales −32.5
    Butyrate-producing bacterium L2—L7 Firmicutes; Lachnospiraceae −27.6
     Clostridium nexile Firmicutes; Lachnospiraceae −26.2
    Bacterium mpn-isolate group 19 Firmicutes; Lachnospiraceae −26.2
    Butyrate-producing bacterium SS2/1 Firmicutes; Lachnospiraceae −24.1
     Alistipes sp. WAL 8169 Bacteroidetes; Bacteroidales −24.0
Enriched in IBD subset
    Drinking-water bacterium Y7 Alphaproteobacteria 76.0
    Actinobacterium GWS-BW-H99 Actinobacteria 62.5
     Nocardioides sp. NS/27 Actinobacteria 61.8
     Novosphingobium sp. K39 Alphaproteobacteria 57.8
     Pseudomonas straminea Betaproteobacteria 53.7
    Gamma proteobacterium DD103 Gammaproteobacteria 50.9
     Bacillus licheniformis Firmicutes;Bacilli 49.7
     Sphingomonas sp. AO1 Alphaproteobacteria 49.6
     Actinomyces oxydans Actinobacteria 48.9
    Acidimicrobidae Ellin7143 Actinobacteria 47.6
  • *Identified by Blast search of database culled of environmental clones.

  • Determined by comparison to rRNA sequence database (49).

  • Difference in prevalence of an OTU between normal subset and IBD subset.