Table 3.

Biochemical and ELISA studies of sera, obtained after a 4-hr fast, from 15-week-old GF and conventionalized Fiaf−/− mice and their wild-type littermates maintained on a low-fat diet

Serum levelsFiaf+/+ (n = 8)Fiaf−/− (n = 6)P value
Glucose, mM6.4 ± 1.66.8 ± 0.80.49
Insulin, ng/ml0.39 ± 0.050.54 ± 0.040.02
Leptin, ng/ml2.90 ± 0.514.93 ± 0.770.04
Triglycerides, mg/dl84.5 ± 16.354.7 ± 3.60.0005
Cholesterol, mg/dl184.4 ± 8.4137.8 ± 9.20.01
Free fatty acids0.95 ± 0.040.99 ± 0.070.65
  • Mean values ± SE are shown.