Table 1.

Example sequences displaying the immunochemical basis of neutralization found from survivor 5 libraries after H5N1 Vietnam panning

Table 1.
  • The 61 unique heavy chain sequences aligned with their germ-line variable regions from the 115 unique heavy and light chain combinations. Required mutations are highlighted in blue, and predominant mutations are highlighted in red. Heavy chain sequences also discovered in H1N1 New Caledonia panning are highlighted in gray. Antibody regions and Kabat numbering ranges are listed at the top of each sequence column.

  • *Paired with 2 unique light chains.

  • Paired with 4 unique light chains.

  • Paired with 3 unique light chains.

  • §Paired with 12 unique light chains.

  • Paired with 5 unique light chains.