Table 1.

Expression profiles of prostate metastasis/invasion related genes in pelvic lymph node tumor (PLN) of pes-ARKO-TRAMP mice and PC3 xenograft tumors compared with PLN of Wt-TRAMP mice and PC-3AR9 xenograft tumors, respectively

Genespes-ARKO-TRAMP(PLN)PC3 (xenograft tumors)
NEPEmbedded Image−5.9± 0.2**Embedded Image−3.7± 0.3**
Cox-23.3± 0.2**6.2± 0.1*
P27Embedded Image−4.6± 0.3**Embedded Image−2.5± 0.4*
MMP-21.2± 0.1N.S.0.5± 0.5N.S.
MMP-96.8± 0.4*8.5± 0.2**
IGF-23.5± 0.3*8.1± 0.3**
IL-63.5± 0.1**3.9± 0.5**
TNFα3.6± 0.4*4.5± 0.9**
RKIPEmbedded Image−2.9± 0.4**Embedded Image−2.6± 0.4**
  • Data are presented as mean ± SD;

  • *, P < 0.05;

  • **, P < 0.01. N.S., no significant difference.