Table 4.

Difference in health status between genotype groups at baseline

Healthy at baseline,* %
P value for trend
Homo. MajorHeter.Homo. MinorUnadjustedAdj. for Case-Control Stat
FOXO3A157.4169.4875.510.010.065
FOXO3A257.3769.3577.080.010.035
FOXO3A357.8968.3475.000.020.097
  • *″Healthy″ is defined as absence of 6 major chronic diseases (CHD, stroke, cancer, PD, COPD and treated type 2 diabetes; high physical function (can walk one-half mile) and high cognitive function (CASI score > 74).