Table 5.

Insulin sensitivity phenotypes according to FOXO3A genotype

FOXO3A Genotype (rs 2802292)
P*
TTTGGG
Fasting glucose, mg/dl
    Average-lived118.4 ± 34.0117.4 ± 38.0115.9 ± 40.10.80
    Long-lived108.3 ± 20.7109.1 ± 23.7110.5 ± 24.10.73
Fasting insulin, mIU/liter
    Average-lived23.7 ± 81.230.4 ± 91.913.2 ± 5.90.004
    Long-lived13.5 ± 9.014.1 ± 13.413.3 ± 9.30.77
Log fasting insulin, mIU/liter
    Average-lived2.68 ± 0.672.73 ± 0.852.47 ± 0.480.03
    Long-lived2.45 ± 0.552.43 ± 0.612.44 ± 0.520.99
HOMA IR Score
    Average-lived9.1 ± 53.010.0 ± 32.23.8 ± 2.40.03
    Long-lived3.7 ± 2.84.0 ± 4.33.6 ± 2.20.55
  • *P value for Student's t test comparing mean values between GG genotype and other groups within cases and controls.